Critical Care & Emergencies (all articles)
Editorial: How I use Transcranial Doppler
6 Jan, 2020 | 23:09h | UTCHow I use Transcranial Doppler – Critical Care (free)
[Abstract Only] Randomized Trial: Angioplasty NOT Non-inferior to CABG for the Treatment of Unprotected Left Main Stenosis
5 Jan, 2020 | 14:19h | UTCPercutaneous coronary angioplasty versus coronary artery bypass grafting in the treatment of unprotected left main stenosis: updated 5-year outcomes from the randomised, non-inferiority NOBLE trial – The Lancet (link to abstract – $ for full-text)
Commentary: NOBLE at 5 Years: New Data Favor CABG for Left Main Disease – TCTMD (free)
Related: BBC Investigation on the Reporting of the EXCEL Trial Raises Concerns Over the Safety of Stents for Left Main Disease in Patients at Low Risk for Surgery (free investigation, video, and commentaries) AND EACTS Calls for Independent Left Main CAD Evidence Review, Urges ESC Input – TCTMD (free) AND Changing Evidence, Changing Practice – European Association of Cardio-Thoracic Surgery (free)
Related Commentary on Twitter
NEW: Percutaneous coronary angioplasty versus coronary artery bypass grafting in the treatment of unprotected left main stenosis: updated 5-year outcomes from the randomised, non-inferiority NOBLE trial https://t.co/T9a6n7CvFp pic.twitter.com/Mw2KdsBQfV
— The Lancet (@TheLancet) December 23, 2019
NICE Guideline: Acute Kidney Injury
5 Jan, 2020 | 14:22h | UTCRelated: Series: Acute Kidney Injury in the Intensive Care Unit – Intensive Care Medicine (free articles) AND Practical approach to detection and management of acute kidney injury in critically ill patient – Journal of Intensive Care (free) AND Sepsis associated acute kidney injury – The BMJ (free) AND Acute kidney injury from sepsis: current concepts, epidemiology, pathophysiology, prevention and treatment – Kidney International (free) AND Drug-induced acute kidney injury diverse mechanisms of tubular injury – Current Opinion in Critical Care (free)
Systematic Review: Decompressive Craniectomy for the Treatment of High Intracranial Pressure in Closed Traumatic Brain Injury
5 Jan, 2020 | 13:36h | UTCDecompressive craniectomy for the treatment of high intracranial pressure in closed traumatic brain injury – Cochrane Library (free)
Related: Consensus statement from the International Consensus Meeting on the Role of Decompressive Craniectomy in the Management of Traumatic Brain Injury – Acta Neurochirurgica (free) AND The Current Status of Decompressive Craniectomy in Traumatic Brain Injury – Current Trauma Reports (free) AND Trial of Decompressive Craniectomy for Traumatic Intracranial Hypertension – New England Journal of Medicine (free)
Review: Perioperative Acute Kidney Injury
5 Jan, 2020 | 13:33h | UTCPerioperative Acute Kidney Injury – Anesthesiology (free)
Related Review: Acute Kidney Injury: A frequently underestimated problem in perioperative medicine – Deutsches Ärzteblatt international (free)
[Abstract Only] Randomized Trial: Rocuronium NOT Non-inferior to Succinylcholine for Endotracheal Intubation Success Rate Among Patients Undergoing Out-of-Hospital Rapid Sequence Intubation
5 Jan, 2020 | 12:57h | UTCEffect of Rocuronium vs Succinylcholine on Endotracheal Intubation Success Rate Among Patients Undergoing Out-of-Hospital Rapid Sequence Intubation: A Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
Commentary: Newer Drug Falls Short for Quick Prehospital Intubation – MedPage Today (free registration required)
Related Commentary on Twitter
In this RCT, #rocuronium did not demonstrate noninferiority vs #succinylcholine in first-attempt intubation success rate in patients undergoing endotracheal intubation in out-of-hospital emergency settings. #rapidsequenceintubation https://t.co/rgw7oVVp3v
— JAMA (@JAMA_current) December 18, 2019
[Abstract Only] Randomized Trial: Aggressive Vasodilation Does Not Improve Outcomes Among Patients with Acute Heart Failure
5 Jan, 2020 | 12:53h | UTCEffect of a Strategy of Comprehensive Vasodilation vs Usual Care on Mortality and Heart Failure Rehospitalization Among Patients With Acute Heart Failure: The GALACTIC Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
Commentary: No Survival Gain From Aggressive Vasodilator Strategy in Acute HF: GALACTIC – Medscape (free registration required)
Related Commentary on Twitter
In this RCT, aggressive sustained vasodilation (nitrates, hydralazine, RAI inhibitors) didn't improve 180-d all-cause mortality or acute rehospitalizations vs usual care in patients w acute heart failure https://t.co/yzLxZAoWBx
— JAMA (@JAMA_current) December 17, 2019
Review: Selective Decontamination of the Digestive Tract in Critically Ill Patients
13 Dec, 2019 | 10:17h | UTC
Guideline: Duodeno-pancreatic and Extrahepatic Biliary Tree Trauma
12 Dec, 2019 | 08:30h | UTC
ASA Practice Guidelines for Central Venous Access 2020
12 Dec, 2019 | 08:31h | UTC
[Abstract Only] Randomized Trial: Vitamin D Not Beneficial for Critically Ill Patients
12 Dec, 2019 | 08:25h | UTCCommentaryy High doses of vitamin D for critically ill patients yield minimal benefit – CU Anschutz Medical Campus (free)
BBC Investigation on the Reporting of the EXCEL Trial Raises Concerns Over the Safety of Stents for Left Main Disease in Patients at Low Risk for Surgery
11 Dec, 2019 | 08:19h | UTCSurgeons withdraw support for heart disease advice – BBC (free)
YouTube Video: European guidelines on heart disease under review – BBC Newsnight (free)
See also: EACTS responds to BBC Newsnight’s investigation on the EXCEL trial – European Association for Cardio-Thoracic Surgery (free)
Commentary: EACTS Pulls Out of Left Main Guidelines After BBC Bombshell Alleging EXCEL Trial Cover-up – TCTMD (free)
Related Commentary on Twitter
Wow! Super ???? breaking story!
Reanalysis of EXCEL using Universal Definition of MI would have changed results substantially.
Taggart may be vindicated.
H/t @MedCrisis @drjohnm https://t.co/Yu7qKuiBdV
— Venk Murthy (@venkmurthy) December 9, 2019
Hyperkalemia: Pathophysiology, Risk Factors and Consequence
11 Dec, 2019 | 08:14h | UTCHyperkalemia: pathophysiology, risk factors and consequences – Nephrology Dialysis Transplantation (free)
Related: Management of hyperkalemia in the acutely ill patient – Annals of Intensive Care (free) AND Acute Management of Hyperkalemia – Current Heart Failure Reports (free) AND Diagnosis and treatment of hyperkalemia – Cleveland Clinic Journal of Medicine (free) AND Potassium Disorders: Hypokalemia and Hyperkalemia – American Family Physician (free) AND Management of hyperkalemia in patients with kidney disease: a position paper endorsed by the Italian Society of Nephrology – Journal of Nephrology (free)
Source: Critical Care Reviews
AHA Scientific Statement: Managing Older Adults in the Cardiac Intensive Care Unit
10 Dec, 2019 | 08:41h | UTCNews Release: Treating more than just the heart is critical for geriatric patients – American Heart Association (free)
Infographics and Summaries of the New ACLS and PALS Updates
10 Dec, 2019 | 08:39h | UTCHomepage: CPR Guidelines (free summaries and infographics)
– 2019 Highlights – Guidelines Update for CPR & ECC
– 2019 FAQ – Guidelines Update for CPR & ECC
– 2019 Infographic – ACLS Guidelines Update
– 2019 Infographic – PALS Guidelines Update
Original Guidelines: AHA Updates on Advanced Cardiovascular Life Support (ACLS) (free) AND AHA Updates in Pediatric Life Support (free)
Related Commentary on Twitter
Have you seen the 2019 @American_Heart guidelines update? @sparsh717, @atolm6, @AylC1989 and @comilla_s have created #infographics to summarize the update! Here is the #ACLS update graphic!
AHA Update: https://t.co/Yo0kdKfZJM
ACLS Update infographic: https://t.co/Vb7R0LgAJI pic.twitter.com/tNadnBC2x5— CanadiEM (@WeAreCanadiEM) December 8, 2019
ESC Position Statement: Imaging in Patients with Suspected Acute Heart Failure
10 Dec, 2019 | 08:37h | UTC
Consensus Report: Lung–kidney Interactions in Critically Ill Patients
10 Dec, 2019 | 08:36h | UTC
Review: Missed Vaccinations and Critical Care Admission
10 Dec, 2019 | 08:35h | UTC
Clinical Update: Mild Traumatic Brain Injury in 2019-2020
10 Dec, 2019 | 08:32h | UTCMild Traumatic Brain Injury in 2019-2020 – JAMA (free for a limited period)
Related: Monitoring and Management of Severe Adult Traumatic Brain Injury Patients with Polytrauma (several guidelines on the subject)
Editorial: Is Tranexamic Acid Going to CRASH the Management of Traumatic Brain Injury?
10 Dec, 2019 | 08:34h | UTCOriginal Study: Effects of tranexamic acid on death, disability, vascular occlusive events and other morbidities in patients with acute traumatic brain injury (CRASH-3): a randomised, placebo-controlled trial – The Lancet (free study and commentaries)
Systematic Review: Corticosteroids for Treating Sepsis in Children and Adults
9 Dec, 2019 | 01:36h | UTCCorticosteroids for treating sepsis in children and adults – Cochrane Library (free)
Summary: Corticosteroids for treating sepsis – Cochrane Library (free)
Related: Adjunctive Corticosteroid Treatment in Septic Shock (review, guideline and meta-analysis on the subject)
ASH Guideline: Prevention of Venous Thromboembolism in Surgical Hospitalized Patients
5 Dec, 2019 | 11:29h | UTCRelated: European guidelines on perioperative venous thromboembolism prophylaxis – European Journal of Anaesthesiology (comprehensive resource on the subject) AND American Society of Hematology 2018 Guidelines for Management of Venous Thromboembolism: Prophylaxis for Hospitalized and Nonhospitalized Medical Patients (free)
Consensus Statement on Fasting Before Procedural Sedation in Adults and Children
5 Dec, 2019 | 11:31h | UTCSee also (preoperative fasting guidelines): Practice Guidelines for Preoperative Fasting and the Use of Pharmacologic Agents to Reduce the Risk of Pulmonary Aspiration: Application to Healthy Patients Undergoing Elective Procedures: An Updated Report by the American Society of Anesthesiologists Task Force on Preoperative Fasting and the Use of Pharmacologic Agents to Reduce the Risk of Pulmonary Aspiration (free) AND Perioperative fasting in adults and children: guidelines from the European Society of Anaesthesiology (free) AND Clear fluids fasting for elective paediatric anaesthesia: The European Society of Anaesthesiology consensus statement – European Journal of Anaesthesiology (free) AND Canadian Pediatric Anesthesia Society statement on clear fluid fasting for elective pediatric anesthesia – Canadian Journal of Anesthesia (free)
Related Commentary on Twitter
?We are delighted to publish the first fasting and aspiration prevention recommendations specific to procedural sedation!
Join us for tonight's TweetChat at 7pm GMT!@SteveGreenMD @mgirwin @gandolfattoNV @LucyOsoyoos @RobackMark @dougcarlson1
?https://t.co/dTBLoCMU0A pic.twitter.com/XTDN98Fy9g
— Anaesthesia (@Anaes_Journal) December 3, 2019
Randomized Trial: Remote Ischemic Preconditioning May Have a Role in Reducing Myocardial Injury in Emergency Hip Fracture Surgery
5 Dec, 2019 | 11:07h | UTCRelated Perspective: Remote ischaemic preconditioning: an intervention for anaesthetists? – British Journal of Anaesthesia (free)
Related Commentary on Twitter
Remote ischaemic preconditioning reduced the risk of myocardial injury and infarction after emergency hip fracture surgery, finds new #BMJresearch https://t.co/Gb45BBpDEB
— The BMJ (@bmj_latest) December 4, 2019
Guidelines for the Management of Paracetamol Poisoning
3 Dec, 2019 | 08:11h | UTCUpdated guidelines for the management of paracetamol poisoning in Australia and New Zealand – The Medical Journal of Australia (free for a limited period)