Critical Care & Emergencies (all articles)
The Science Underlying COVID-19: Implications for the Cardiovascular System
20 Apr, 2020 | 00:19h | UTCThe Science Underlying COVID-19: Implications for the Cardiovascular System – Circulation
Editorial: COVID-19 Pneumonia: ARDS or Not? – Critical Care
20 Apr, 2020 | 00:09h | UTCEditorial: COVID-19 pneumonia: ARDS or not? – Critical Care
Related: COVID-19 pneumonia: different respiratory treatment for different phenotypes? – Intensive Care Medicine AND Covid-19 Does Not Lead to a “Typical” Acute Respiratory Distress Syndrome – American Journal of Respiratory and Critical Care Medicine
Disruptive Modifications to Cardiac Critical Care Delivery During the Covid-19 Pandemic
20 Apr, 2020 | 00:14h | UTC
What’s Happening with Remdesivir?
20 Apr, 2020 | 00:12h | UTCWhat’s Happening With Remdesivir? – Science Translational Medicine
See also: Slow down your giddyup on Gilead news – Health News Review
Defining ARDS & Recruitability, with Implications for COVID Treatment
20 Apr, 2020 | 00:06h | UTCDefining ARDS & recruitability, with implications for COVID treatment – PulmCrit
Hospital Preparedness for COVID-19: A Practical Guide from a Critical Care Perspective
20 Apr, 2020 | 00:07h | UTC
Observational Study: Inpatient Use of Angiotensin Converting Enzyme Inhibitors and Angiotensin II Receptor Blockers Seems Safe Among Patients with Hypertension Hospitalized With COVID-19
20 Apr, 2020 | 00:01h | UTC
Coronavirus: Nine in 10 Dying Have Existing Illness
17 Apr, 2020 | 02:20h | UTCCoronavirus: Nine in 10 dying have existing illness – BBC
Original Report: Deaths involving COVID-19, England and Wales: deaths occurring in March 2020 – Office for National Statistics
Study Commentary: Hydroxychloroquine Fails First Meaningful RCT
17 Apr, 2020 | 02:25h | UTCHydroxychloroquine fails first meaningful RCT – PulmCrit
Original Study: Hydroxychloroquine for Covid-19: No Benefit in New Open-label, Randomized Trial
Related Commentary: Hydroxychloroquine in the management of critically ill patients with COVID-19: the need for an evidence base – The Lancet Respiratory Medicine
Pathological Evidence of Pulmonary Thrombotic Phenomena in Severe COVID-19
17 Apr, 2020 | 02:24h | UTC* We congratulate the authors for this significant contribution to the understanding of this disease.
Meta-Analysis: Hematologic, Biochemical and Immune Biomarker Abnormalities Associated with Severe Illness and Mortality in COVID-19
17 Apr, 2020 | 02:22h | UTC“non-survivors compared to survivors had more significant increases in WBC count, total bilirubin, creatine kinase, serum ferritin, and interleukin 6 (IL-6), and more significant decreases in lymphocyte count and platelet count.”
Chest CT and Coronavirus Disease (COVID-19): A Critical Review of the Literature to Date
17 Apr, 2020 | 02:08h | UTC
Management of the Hospitalized COVID-19 Patient with Acute Cardiomyopathy or Heart Failure
17 Apr, 2020 | 02:05h | UTC
German Recommendations for Critically Ill Patients with COVID 19
17 Apr, 2020 | 02:02h | UTC
Neurologic Features in Severe SARS-CoV-2 Infection
16 Apr, 2020 | 02:56h | UTCNeurologic Features in Severe SARS-CoV-2 Infection – New England Journal of Medicine
Related Study: Neurologic Manifestations Common in Hospitalized Patients with Covid-19 (study and commentaries)
Review: Hematological Findings and Complications of COVID‐19
16 Apr, 2020 | 02:40h | UTCHematological findings and complications of COVID‐19 – American Journal of Hematology
Evidence Based Management Guideline for the COVID-19 Pandemic
16 Apr, 2020 | 02:48h | UTC
COVID-19 and Coagulopathy: Frequently Asked Questions
16 Apr, 2020 | 02:39h | UTCCOVID-19 and Coagulopathy: Frequently Asked Questions – American Society of Hematology
Related: Possible Algorithm to Empiric Anticoagulation in COVID-19 Based on D-Dimer (3 guidance papers with different approaches)
Review by Dr. Martin Tobin – Basing Respiratory Management of Coronavirus on Physiological Principles
15 Apr, 2020 | 03:36h | UTC
Related Commentary on Twitter (Thread – Click for More)
some pearls from an article by Martin Tobin about when to intubate patients with COVID (yep, the same one who edited Tobin's textbook on mechanical ventilation)… (#1/6)
(full article: https://t.co/YNeETU077D) pic.twitter.com/bpkEsJ6m2R— 𝙟𝙤𝙨𝙝 𝙛𝙖𝙧𝙠𝙖𝙨 💊 (@PulmCrit) April 14, 2020
Hydroxychloroquine for Covid-19: No Benefit in New Open-label, Randomized Trial
15 Apr, 2020 | 03:42h | UTC[Preprint] Hydroxychloroquine in patients with COVID-19: an open-label, randomized, controlled trial – medRxiv
See also just published observational study (Preprint): No evidence of clinical efficacy of hydroxychloroquine in patients hospitalized for COVID-19 infection with oxygen requirement: results of a study using routinely collected data to emulate a target trial – medRxiv
Related Commentary on Twitter
#COVID19 Here comes another dataset of #Hydroxychloroquine from an open-label randomized controlled trial in Chinahttps://t.co/qW93wMDILK
No difference in 28-day #coronavirus negative conversion rate for HCQ + SOC vs SOC
No difference in 28-day symptoms alleviation rate either pic.twitter.com/pOsBSQWeuO
— Andy Biotech (@AndyBiotech) April 14, 2020
FDA Issues Emergency Use Authorization to Decontaminate Millions of N95 Respirators
15 Apr, 2020 | 03:38h | UTCCommentary: FDA clears N95 decontamination process that could clean up to 4 million masks per day – Tech Crunch
Implementation Guide: Triage of Scarce Critical Care Resources in COVID-19
15 Apr, 2020 | 03:23h | UTC
Infective Endocarditis: A Contemporary Review
15 Apr, 2020 | 03:13h | UTCInfective Endocarditis: A Contemporary Review – Mayo Clinic Proceedings
Review: Diagnostic Testing for SARS-CoV-2
14 Apr, 2020 | 03:06h | UTC
Review: Pharmacologic Treatments for COVID-19
14 Apr, 2020 | 03:05h | UTCPharmacologic Treatments for Coronavirus Disease 2019 (COVID-19): A Review – JAMA