Critical Care & Emergencies (all articles)
Small Observational Study Suggests Prophylactic LMWH Can Prevent COVID‐19 Disseminated Intravascular Coagulopathy
1 May, 2020 | 03:26h | UTCCOVID‐19 Coagulopathy in Caucasian patients – British Journal of Haematology
Treatment Considerations for COVID-19: A Critical Review of the Evidence
1 May, 2020 | 03:20h | UTC
COVID-19 and the Cardiovascular System: Implications for Risk Assessment, Diagnosis, and Treatment Options
1 May, 2020 | 03:18h | UTCRelated Guidelines: COVID-19 rapid guideline: acute myocardial injury – National Institute for Health and Care Excellence AND ESC Guidance for the Diagnosis and Management of CV Disease during the COVID-19 Pandemic – European Society of Cardiology AND Management of Acute Myocardial Infarction During the COVID-19 Pandemic – Journal of the American Academy of Cardiology
Perspective: Urging Caution on Remdesivir
1 May, 2020 | 03:07h | UTCUrging Caution On Remdesivir – Forbes
Related: About Remdesivir and About “Game-Changers” – Science Translational Medicine AND Conflicting Remdesivir Trial Results Released; Experts Urge More Research – Health Policy Watch AND Is remdesivir a miracle drug to cure coronavirus? Don’t get your hopes up yet – The Conversation AND PulmCrit- First placebo-controlled RCT on remdesivir for COVID-19 – PulmCrit AND Remdesivir: the antiviral drug is being touted as a possible coronavirus treatment – but will it work? – The Guardian
“While I have enormous respect for the Institutes and their leaders, releasing the preliminary news without sharing the data behind it is highly irresponsible.”
Review: Neurologic Comorbidities and Complications in Patients Hospitalized for COVID-19
1 May, 2020 | 03:03h | UTCRelated Studies: Neurologic Features in Severe SARS-CoV-2 Infection – New England Journal of Medicine AND Neurologic Manifestations Common in Hospitalized Patients with Covid-19 (study and commentaries)
COVID-19: ICU Delirium Management During SARS-CoV-2 Pandemic
1 May, 2020 | 02:54h | UTCCOVID-19: ICU delirium management during SARS-CoV-2 pandemic – Critical Care
Clinical Determinants for Fatality of 44,672 Patients with COVID-19
1 May, 2020 | 02:48h | UTCClinical determinants for fatality of 44,672 patients with COVID-19 – Critical Care
Randomized Trial: Remdesivir Not Beneficial for Adults with Severe COVID-19
30 Apr, 2020 | 04:31h | UTCCommentaries: First randomized trial of remdesivir suggests antiviral drug is not associated with significant clinical benefits, more research needed – The Lancet AND Expert reaction to trial of remdesivir in adults – Science Media Centre
See also: [Not Published Yet] NIH Study Shows Remdesivir Accelerates Recovery from Advanced COVID-19
Related Commentary on Twitter
With all the hype about Remdesivir today @TheLancet has decided to lift the embargo and release this placebo-controlled multicenter study done in China that showed no benefit https://t.co/ZdmKfnWLyw
— Carlos del Rio (@CarlosdelRio7) April 29, 2020
[Not Published Yet] NIH Study Shows Remdesivir Accelerates Recovery from Advanced COVID-19
30 Apr, 2020 | 04:28h | UTCCommentaries: Hopes rise on coronavirus drug remdesivir – Nature AND The COVID-19 research news rollercoaster is running again: STAT News + Gilead’s remdesivir – HealthNews Review
See also: Randomized Trial: Remdesivir Not Beneficial for Adults with Severe COVID-19
COVID-19 and Its Implications for Thrombosis and Anticoagulation
30 Apr, 2020 | 04:13h | UTCCOVID-19 and its implications for thrombosis and anticoagulation – Blood
Consensus Statement on Fundamental Concepts in Perioperative Fluid Management
30 Apr, 2020 | 03:51h | UTC
Large-Vessel Stroke as a Presenting Feature of Covid-19 in the Young
29 Apr, 2020 | 05:21h | UTC
Lung Pathology of COVID-19: Is AFOP in Play?
29 Apr, 2020 | 04:58h | UTCLung pathology of COVID-19: is AFOP in play? – PulmCrit
Why Don’t Some Coronavirus Patients Sense their Alarmingly Low Oxygen Levels?
29 Apr, 2020 | 05:11h | UTCWhy don’t some coronavirus patients sense their alarmingly low oxygen levels? – Science
Randomized Trial: Beta-Blocker Therapy Promising in Severe Traumatic Brain Injury
29 Apr, 2020 | 04:47h | UTCRelated Meta-Analysis: Beta-Blockers and Traumatic Brain Injury: A Systematic Review and Meta-Analysis – Annals of Surgery
“We recommend further high-quality trials to answer questions about the mechanisms of action, effectiveness on subgroups, dose-response, length of therapy, functional outcome, and quality of life after β-blocker use for TBI” (from the 2017 meta-analysis above)
Report: Diagnosis, Prevention, and Treatment of Thromboembolic Complications in COVID-19
28 Apr, 2020 | 04:45h | UTC
IDSA Guidelines on Infection Prevention in Patients with Suspected or Known COVID-19
28 Apr, 2020 | 04:47h | UTC
Study: COVID-19 and Risks Posed to Personnel During Endotracheal Intubation
28 Apr, 2020 | 04:40h | UTCEditorial: COVID-19 and Risks Posed to Personnel During Endotracheal Intubation – JAMA
Twitter-based Learning for Continuing Medical Education? A New Perspective for a Paradigm Shift in Medical Education, Accelerated by COVID-19
28 Apr, 2020 | 04:28h | UTCRelated: How Twitter is Changing Medical Research (texts on the subject)
Closely Watched Arthritis Drug Disappoints as a Covid-19 Treatment, Studies Show
28 Apr, 2020 | 04:18h | UTCClosely watched arthritis drug disappoints as a Covid-19 treatment, studies show – STAT
Clinical Practice: Mild or Moderate Covid-19
26 Apr, 2020 | 21:35h | UTCMild or Moderate Covid-19 – New England Journal of Medicine
Management of COVID-19 Respiratory Distress
26 Apr, 2020 | 21:36h | UTCManagement of COVID-19 Respiratory Distress – JAMA
Related Podcast: Coronavirus (COVID-19) Update: Ventilatory Management for COVID-Related Respiratory Failure – JAMA
Related Commentary on Twitter
Treatment guidelines for #ARDS still guide the care of critically ill #COVID19 patients, including conservative fluid strategies for patients without shock, lung-protective ventilation, prone positioning, and consideration of ECMO for refractory #hypoxemia https://t.co/7G0WoTiUQl
— JAMA (@JAMA_current) April 24, 2020
Transforming Operating Rooms into ICUs
26 Apr, 2020 | 21:34h | UTCTransforming ORs into ICUs – New England Journal of Medicine
Study: The QT Interval in Patients with COVID-19 Treated with Hydroxychloroquine and Azithromycin
26 Apr, 2020 | 21:18h | UTC
FDA Safety Alert: Risk of Heart Rhythm Problems with the use of Hydroxychloroquine or Chloroquine for COVID-19
26 Apr, 2020 | 21:20h | UTCNews Release: FDA warning for Hydroxychloroquine or Chloroquine for COVID-19: Risk of Heart Rhythm Problems – Outbreak News Today