Critical Care & Emergencies (all articles)
LDH, Lymphocyte Count, and C-reactive protein can Predict Mortality in Covid-19
18 May, 2020 | 01:58h | UTCAn interpretable mortality prediction model for COVID-19 patients – Nature Machine Learning
Related Commentary on Twitter
The importance of 3 blood test results for predicting mortality from #COVID19: LDH, lymphocyte count, and C-reactive protein https://t.co/BpbgLkm6Hs just published @NatMachIntell, a nice example of machine learning deconvoluting risk markers pic.twitter.com/JtBofSdwsM
— Eric Topol (@EricTopol) May 14, 2020
Guidance for Tracheostomy in the COVID-19 Era
18 May, 2020 | 02:05h | UTCCommentary: Walking the line between benefit and harm from tracheostomy in COVID-19 – The Lancet Respiratory Medicine
Clinical and Chest Radiography Features Determine Patient Outcomes In COVID-19
18 May, 2020 | 01:59h | UTC
Use of Prone Positioning in Nonintubated Patients With COVID-19 and Hypoxemic Acute Respiratory Failure
18 May, 2020 | 01:52h | UTCEditorial: Is the Prone Position Helpful During Spontaneous Breathing in Patients With COVID-19?
Randomized Trial: Graduated Compression Stockings in Elective Surgical Patients
18 May, 2020 | 01:41h | UTCCommentaries: Graduated compression stockings on trial – The BMJ Opinion AND Compression stockings might not be needed to prevent blood clots after surgery – The British Medical Journal
[Preprint] Early Safety Indicators of COVID-19 Convalescent Plasma in 5,000 Patients
15 May, 2020 | 03:50h | UTCEarly Safety Indicators of COVID-19 Convalescent Plasma in 5,000 Patients – medRxiv
Commentary: Convalescent plasma is safe to treat COVID-19: nationwide study – NBC News
Systematic Review: Plasma from People who Have Recovered from COVID-19 to Treat Individuals with COVID-19
15 May, 2020 | 03:48h | UTC
ACP Systematic Review: Chloroquine or Hydroxychloroquine Alone or in Combination with Azithromycin for the Prophylaxis or Treatment of COVID-19
15 May, 2020 | 03:32h | UTC
Guideline: Management of the Neurologically Deceased Organ Donor
15 May, 2020 | 03:20h | UTC
Study Commentary: Before/after Study of Short-Course Steroid in COVID-19
14 May, 2020 | 10:09h | UTCBefore/after study of short-course steroid in COVID-19 – PulmCrit
Original Study (Preprint): Early Short Course Corticosteroids in Hospitalized Patients with COVID-19 – medRxiv
Meta-Analysis: Manifestations and Prognosis of Gastrointestinal and Liver Involvement in COVID-19
14 May, 2020 | 10:16h | UTCRelated: Gastrointestinal, Hepatobiliary, and Pancreatic Manifestations of COVID-19 (review and guideline) AND Abdominal Imaging Findings in COVID-19: Preliminary Observations – Radiology
Review: Pulmonary Complications Associated with Veno-arterial ECMO
14 May, 2020 | 02:22h | UTC
New Clinical Risk Score to Predict the Occurrence of Critical Illness in Hospitalized Patients With COVID-19
13 May, 2020 | 02:14h | UTCSee also: Calculation Tool For Predicting Critical-ill COVID-19 At Admission
Related Preprint Study (just published): Development and validation of the COVID-19 severity index (CSI): a prognostic tool for early respiratory decompensation – medRxiv AND Calculation Tool: https://covidseverityindex.org/
Study Commentary – Virus Wars: Return of Lopinavir/Ritonavir (Along with Ribavirin and Interferon)
13 May, 2020 | 02:12h | UTCVirus Wars: Return of Lopinavir/Ritonavir (along with ribavirin and interferon) – PulmCrit
Original Article: Triple Therapy Antiviral Combination Seems Promising for COVID-19 in Open-label, Randomized, Phase 2 Trial (study and commentaries)
Hydroxychloroquine in Patients with COVID-19: A Systematic Review and Meta-analysis
13 May, 2020 | 01:53h | UTC“While initial studies with hydroxychloroquine showed some ray of hope, recent studies that have emerged found either no benefit or a possible harm in COVID-19.”
Remdesivir in COVID-19: A Critical Review of Pharmacology, Pre-clinical and Clinical Studies
13 May, 2020 | 01:50h | UTC“While the first double-blind, randomized-controlled trial (DBRCT) found no significant benefit with remdesivir compared to placebo, preliminary reports from another DBRCT showed a significant faster recovery, without any difference in mortality.”
Observational Study: Hydroxychloroquine, Azithromycin, or Both Not Associated with Lower In-hospital Mortality
12 May, 2020 | 03:39h | UTC
Abdominal Imaging Findings in COVID-19: Preliminary Observations
12 May, 2020 | 03:28h | UTCAbdominal Imaging Findings in COVID-19: Preliminary Observations – Radiology
News Release: Imaging reveals bowel abnormalities in patients with COVID-19 – Radiological Society of North America
Coagulation Abnormalities and Thrombosis in Patients with COVID-19
12 May, 2020 | 03:16h | UTCCoagulation abnormalities and thrombosis in patients with COVID-19 – The Lancet
Related Commentary on Twitter
Good to see these welcome recommendations today for diagnosis of clotting and its prevention in patients with severe #COVID19 @TheLancetHaem https://t.co/RrtXSIu2Ne by @MarcelLevi @JerroldLevy and colleagues pic.twitter.com/dU17RIj1f2
— Eric Topol (@EricTopol) May 11, 2020
Perspective: Which COVID-19 Antivirals Actually Work?
12 May, 2020 | 03:18h | UTCPerspective: Which COVID-19 Antivirals Actually Work? – Forbes
Related: Hong Kong Doctors See Progress In Treatment Of COVID-19 – Forbes
Triple Therapy Antiviral Combination Seems Promising for COVID-19 in Open-label, Randomized, Phase 2 Trial
11 May, 2020 | 00:42h | UTCCommentaries: Interferon beta-1b for COVID-19 – The Lancet AND New triple antiviral drug combination shows early promise for treating COVID-19 in phase 2 randomized trial – The Lancet AND A Drug Cocktail Hastens Recovery in Some Coronavirus Patients – The New York Times AND Triple drug therapy helps coronavirus patients recover more quickly, study finds – CNN AND Triple antiviral drug shows early promise in COVID-19 trial – Reuters AND Expert reaction to a study about a phase 2 trial of a triple antiviral drug combination treatment for COVID-19 – Science Media Centre
Preliminary Study Evaluates Interleukin-1 Blockade for Patients with Severe Covid-19
11 May, 2020 | 00:34h | UTCCommentaries: Expert reaction to study looking at use of arthritis drug anakinra in hospitalised patients with severe COVID-19 – Science Media Centre AND Small study of patients with severe COVID-19 treated with the arthritis drug anakinra finds clinical improvements – The Lancet
Revisited: Therapeutic and Toxic Blood Concentrations of More than 1100 drugs and Other Xenobiotics
11 May, 2020 | 00:15h | UTC
Meta-Analysis: Furosemide Stress Test as a Predictive Marker of Acute Kidney Injury Progression or Renal Replacement Therapy
11 May, 2020 | 00:12h | UTC
Position Paper: Antimicrobial Therapeutic Drug Monitoring in Critically Ill Adult Patients
11 May, 2020 | 00:19h | UTCCommentary: New antibiotic guidelines could save more lives in intensive care units – News Medical