Critical Care & Emergencies (all articles)
A Compendium Answering 150 Questions on COVID‐19 and SARS‐CoV‐2
23 Jun, 2020 | 08:38h | UTCA compendium answering 150 questions on COVID‐19 and SARS‐CoV‐2 – Allergy
Position Paper for the State-of-the-Art Application of Respiratory Support in Patients with COVID-19
23 Jun, 2020 | 08:40h | UTC
Drug Dosing in the Critically ill Obese Patient—A Focus on Sedation, Analgesia, and Delirium
23 Jun, 2020 | 08:15h | UTC
Related Commentary on Twitter
#CritCare #OpenAccess https://t.co/AXi5FOLBAC#Drug_dosing recommendations are often based on patients with normal body habitus. What about #pharmacokinetics of critically ill #obese patients?#FOAMed #FOAMcc #BMC #ICU @jlvincen @ISICEM #obesity #pain #agitation #delirium pic.twitter.com/QMWEmeyDpX
— Critical Care (@Crit_Care) June 23, 2020
NIH Halts Clinical Trial of Hydroxychloroquine
21 Jun, 2020 | 23:44h | UTCNIH halts clinical trial of hydroxychloroquine – NIH News Releases
Characteristics Associated with Out-of-Hospital Cardiac Arrests and Resuscitations During the Covid-19 Pandemic in New York City
21 Jun, 2020 | 23:33h | UTCEditorial: Heroism in the Face of the COVID-19 Pandemic
Related Commentary on Twitter
A doubling (and >4X at peak) of out-of-hospital cardiac arrests, with 90% of leading to deaths, in New York City during its #COVID19 outbreak @JAMACardio https://t.co/PbtzAvCoNY likely reflects collateral damage—fear of medical attention (covid & cardiac) + direct heart impact pic.twitter.com/jJwF1hF61T
— Eric Topol (@EricTopol) June 19, 2020
Feasibility and Physiological Effects of Prone Positioning in Non-intubated Patients with Acute Respiratory Failure due to COVID-19
21 Jun, 2020 | 23:34h | UTCCommentaries: Prone positioning in non-intubated patients with COVID-19: raising the bar – The Lancet Respiratory Medicine AND Prone position ups oxygenation in patients with severe COVID-19 – MedicalXpress
Related: Prone Positioning in Awake, Nonintubated Patients With COVID-19 Hypoxemic Respiratory Failure (related study and guideline) AND Awake prone positioning in COVID-19 – Thorax
Procedural Sedation in the COVID-19 Era
21 Jun, 2020 | 23:30h | UTCProcedural sedation in the COVID-19 era – Cleveland Clinic Journal of Medicine
ACP: Advice on Use of N95, Surgical, and Cloth Masks to Prevent COVID-19
19 Jun, 2020 | 09:47h | UTC
[Preprint] Limited Role for Antibiotics in COVID-19: Scarce Evidence of Bacterial Coinfection
19 Jun, 2020 | 09:36h | UTCLimited Role for Antibiotics in COVID-19: Scarce Evidence of Bacterial Coinfection – medRxiv
Related Commentary on Twitter
Limited Role for Antibiotics in COVID-19: Scarce Evidence of Bacterial Coinfection | pre-peer review in @medrxivpreprint colleagues from @UTSWInfDis remind us that bacterial co-infections are UNCOMMON in #Covid_19 so don’t use antibiotics! https://t.co/dpNLRZiOZn
— Carlos del Rio (@CarlosdelRio7) June 18, 2020
Ethical Dilemmas Due to the Covid-19 Pandemic
19 Jun, 2020 | 09:33h | UTCEthical dilemmas due to the Covid-19 pandemic – Annals of Intensive Care
Randomized Trial: Tranexamic Acid Does Not Reduce Death from Gastrointestinal Bleeding
19 Jun, 2020 | 09:32h | UTCInvited Commentary: Tranexamic acid for severe gastrointestinal bleeding – The Lancet
Blood Type Linked to Outcomes in Covid-19 Patients: Type O May Be Protective and Type A May Increase Risk
18 Jun, 2020 | 09:12h | UTCCommentary: Study ties blood type to COVID-19 risk; O may help, A hurt – Associated Press
Prone Positioning in Awake, Nonintubated Patients With COVID-19 Hypoxemic Respiratory Failure
18 Jun, 2020 | 09:07h | UTCInvited Commentary: Prone Positioning in Awake, Nonintubated Patients With COVID-19: Necessity Is the Mother of Invention – JAMA Internal Medicine
ACP Update Alert: Should Clinicians Use Chloroquine or Hydroxychloroquine Alone or in Combination with Azithromycin for the Prophylaxis or Treatment of COVID-19?
18 Jun, 2020 | 08:59h | UTC
WHO To Include Dexamethasone in Updated COVID-19 Care Guidelines; Drops Hydroxychloroquine from Massive Solidarity Trial
18 Jun, 2020 | 09:02h | UTCSee also: WHO drops hydroxychloroquine from Covid-19 clinical trial – STAT AND WHO halts malaria drug study, eyes steroid for COVID-19 – CIDRAP AND Steroid should be kept for serious coronavirus cases, WHO says – Reuters
Position Paper: Guidance on Diagnosis, Prevention and Treatment of Thromboembolic Complications in COVID-19
18 Jun, 2020 | 09:03h | UTC
Study Commentary: Haloperidol for Headache – THE HA Study RCT
18 Jun, 2020 | 08:44h | UTCHaloperidol for Headache – THE HA Study RCT – Journal Feed
Original Study: Treatment of Headache in the Emergency Department: Haloperidol in the Acute Setting (THE-HA Study): A Randomized Clinical Trial – The Journal of Emergency Medicine (link to abstract – $ for full-text)
Randomized Trial: Dexamethasone Reduces Death by Up to One Third in Patients with Severe COVID-19
17 Jun, 2020 | 02:49h | UTCCommentaries: Coronavirus breakthrough: dexamethasone is first drug shown to save lives – Nature AND WHO welcomes preliminary results about dexamethasone use in treating critically ill COVID-19 patients – World Health Organization AND Major study finds common steroid reduces deaths among patients with severe Covid-19 – STAT AND Dexamethasone reduces death in hospitalised patients with severe respiratory complications of COVID-19 – University of Oxford AND Coronavirus: Dexamethasone proves first life-saving drug – BBC
Related Commentary on Twitter
Dexamethasone reduced deaths by 1/3rd in ventilated patients (rate ratio 0.65 [95% CI 0.48 to 0.88]; p=0.0003) and by 1/5th in patients receiving oxygen only (0.80 [0.67 to 0.96]; p=0.0021). No benefit in patients not requiring respiratory support (1.22 [0.86 to 1.75; p=0.14).
— Peter Horby (@PeterHorby) June 16, 2020
CDC Report: Hospitalizations for Covid-19 Six Times Higher and Deaths 12 times Higher Among Those with Underlying Conditions
16 Jun, 2020 | 08:19h | UTCCommentary: COVID-19 patients with underlying health conditions are 12 times more likely to die: CDC – The Hill
COVID-19 Update: FDA Revokes Emergency Use Authorization for Chloroquine and Hydroxychloroquine
16 Jun, 2020 | 08:10h | UTCCommentaries: FDA Withdraws Emergency Use Authorization For Hydroxychloroquine – NPR AND FDA revokes authorization of drug Trump touted – CNN
Thromboelastographic Results and Hypercoagulability Syndrome in Patients with Coronavirus Disease 2019 Who Are Critically Ill
16 Jun, 2020 | 07:58h | UTC
Randomized Trial: Ruxolitinib for the Treatment of Severe COVID-19
16 Jun, 2020 | 07:55h | UTCCommentary: Multicenter RCT evaluating ruxolitinib (a JAK inhibitor) for COVID-19 – PulmCrit
Editorial: How I Approach Weaning from Venoarterial ECMO
16 Jun, 2020 | 07:49h | UTCHow I approach weaning from venoarterial ECMO – Critical Care
Neuropathological Features of Covid-19
15 Jun, 2020 | 03:35h | UTCNeuropathological Features of Covid-19 – New England Journal of Medicine
Review: Acute Kidney Injury in Critically ill Patients with COVID-19
15 Jun, 2020 | 03:41h | UTCAcute kidney injury in critically ill patients with COVID-19 – Intensive Care Medicine