Emergency Medicine
RCT | Rivaroxaban shows promise compared to Enoxaparin in the acute phase of an acute coronary syndrome
16 Feb, 2023 | 15:20h | UTCInvited Commentary: Rivaroxaban for Patients With Acute Coronary Syndromes—Where Do We Stand? – JAMA Network Open
Commentary on Twitter
The H-REPLACE RCT: short-term rivaroxaban (5mg 2x/day) was noninferior to enoxaparin in safety + efficacy during 6-month follow-up among patients with acute coronary syndrome who missed the primary reperfusion window and before selective revascularization. https://t.co/TIHOwGSWjJ
— JAMA Network Open (@JAMANetworkOpen) February 10, 2023
Guideline | Diagnosis and management of subarachnoid hemorrhage caused by a ruptured aneurysm
16 Feb, 2023 | 15:23h | UTC
M-A | Efficacy of endovascular therapy for basilar and vertebral artery occlusion
16 Feb, 2023 | 14:50h | UTCRelated:
M-A | Mechanical thrombectomy in acute basilar artery stroke.
Review | Indications, clinical impact, and complications of critical care transesophageal echocardiography
15 Feb, 2023 | 15:45h | UTC
SR | Predisposing and precipitating factors associated with delirium
15 Feb, 2023 | 15:38h | UTC
Consensus Paper | ED management of patients with alcohol intoxication, alcohol withdrawal, and alcohol use disorder
14 Feb, 2023 | 11:05h | UTC
Review | Anisocoria in the ED: pathophysiology, evaluation, and management
14 Feb, 2023 | 10:41h | UTCAnisocoria in the ED: Pathophysiology, Evaluation, and Management – emDocs
RCT | Tenecteplase noninferior to alteplase in acute ischemic cerebrovascular events
13 Feb, 2023 | 12:59h | UTCTenecteplase versus alteplase in acute ischaemic cerebrovascular events (TRACE-2): a phase 3, multicentre, open-label, randomised controlled, non-inferiority trial – The Lancet (link to abstract – $ for full-text)
RCTs | Endovascular therapy improves functional outcomes in large ischemic strokes, but increases bleeding and vascular complications
13 Feb, 2023 | 13:00h | UTCStudy 1: Trial of Endovascular Thrombectomy for Large Ischemic Strokes – New England Journal of Medicine (link to abstract – $ for full-text)
Study 2: Trial of Endovascular Therapy for Acute Ischemic Stroke with Large Infarct – New England Journal of Medicine (link to abstract – $ for full-text)
M-A | Tenecteplase vs. alteplase for treatment of acute ischemic stroke
13 Feb, 2023 | 12:57h | UTCRelated: Tenecteplase versus alteplase in acute ischaemic cerebrovascular events (TRACE-2): a phase 3, multicentre, open-label, randomised controlled, non-inferiority trial – The Lancet (link to abstract – $ for full-text)
Brief Review | Double sequential external defibrillation for refractory ventricular fibrillation
13 Feb, 2023 | 12:35h | UTC
Commentary on Twitter
?Refractory Vfib
⚡️ vector change defibrillation
⚡️ double sequential external defibrillation
exciting & innovative strategies that can improve survival for patients presenting with refractory VF: time will tell if will be broadly implemented/embraced
?️ https://t.co/uUktOHdGEl pic.twitter.com/aiOtMMX2nT— Intensive Care Medicine (@yourICM) February 9, 2023
Guideline for management of septic arthritis in native joints
10 Feb, 2023 | 14:00h | UTC
RCT | Argatroban plus Alteplase not better than Alteplase alone in patients with acute ischemic stroke
10 Feb, 2023 | 13:59h | UTCEffect of Argatroban Plus Intravenous Alteplase vs Intravenous Alteplase Alone on Neurologic Function in Patients With Acute Ischemic Stroke: The ARAIS Randomized Clinical Trial – JAMA (free for a limited period)
Commentary on Twitter
Among patients with acute ischemic #stroke who received intravenous alteplase, argatroban was not significantly associated with better neurologic function. https://t.co/s9BDEvRvFA pic.twitter.com/HIRnGmiWMU
— JAMA (@JAMA_current) February 9, 2023
Review | Management of adult patients with hematological malignancies in critical care
10 Feb, 2023 | 13:45h | UTCManagement of adult patients with haematological malignancies in critical care – Anaesthesia
[Not published yet] Dual blood thinners under prescribed after minor or warning stroke, especially in women
9 Feb, 2023 | 14:01h | UTCRelated:
How to use biomarkers of infection or sepsis at the bedside: guide to clinicians
9 Feb, 2023 | 13:26h | UTC
Commentary on Twitter
Infection or #sepsis at bedside:
? how to use biomarkers? Serial determinations & never as stand-alone test: do not miss clinical evaluation
? pathogen‑specific & host‑response biomarkers? useful to provide additional data to optimize care
? future
?️ https://t.co/Z3Hgb2I6o1 pic.twitter.com/bX4PanG2Et— Intensive Care Medicine (@yourICM) January 2, 2023
Brief Review | Acute kidney injury
9 Feb, 2023 | 13:25h | UTCAcute kidney injury – Intensive Care Medicine
Commentary on Twitter
Acute kidney injury
? contributing mechanisms
? emerging trends
Deeper understanding of complex pathophysiology offers opportunities for new therapies & reno-protective strategies, supported by tools to accurately measure kidney function in real time.
?️ https://t.co/9RdU5AFD68 pic.twitter.com/LYgt9d21EQ— Intensive Care Medicine (@yourICM) January 3, 2023
Guideline | Assessment and management of complex fractures
7 Feb, 2023 | 14:19h | UTCFractures (complex): assessment and management – National Institute for Health and Care Excellence
Guideline | Delirium: prevention, diagnosis and management in hospital and long-term care
7 Feb, 2023 | 14:21h | UTC
RCT | Paxlovid did not improve outcomes in hospitalized patients with Covid-19
7 Feb, 2023 | 14:08h | UTC
M-A | Heparin full-dose anticoagulation is beneficial for non-critically ill COVID-19 patients
7 Feb, 2023 | 14:06h | UTCRelated:
Anticoagulants for people hospitalised with COVID‐19 – Cochrane Library
Complications of diagnostic upper gastrointestinal endoscopy: recognition, assessment and management
7 Feb, 2023 | 13:41h | UTC
Cohort Study | Predictors of acute coronary occlusion in patients with out-of-hospital cardiac arrest without ST-segment elevation
3 Feb, 2023 | 14:20h | UTCAcute Coronary Occlusion in Patients With Non-ST-Segment Elevation Out-of-Hospital Cardiac Arrest – Journal of the American College of Cardiology (link to abstract – $ for full-text)
JACC Podcast: Acute Coronary Occlusion in Patients with Non-ST-segment Elevation Out-of-hospital Cardiac Arrest
Commentary: Coronary Occlusion in Patients With Non-ST Elevation Cardiac Arrest – American College of Cardiology
Related:
Emergency vs Delayed Coronary Angiogram in Survivors of Out-of-Hospital Cardiac Arrest: Results of the Randomized, Multicentric EMERGE Trial – JAMA Cardiology (link to abstract – $ for full-text)
Transfusion thresholds for acute coronary syndromes — insights from the TRICS‐III trial and meta‐analysis
3 Feb, 2023 | 13:58h | UTC
RCT | Remifentanil vs. neuromuscular blockers during rapid sequence intubation in patients at risk of aspiration
2 Feb, 2023 | 15:01h | UTCEffect of Remifentanil vs Neuromuscular Blockers During Rapid Sequence Intubation on Successful Intubation Without Major Complications Among Patients at Risk of Aspiration: A Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
Commentary on Twitter
Among adults at risk of aspiration during rapid sequence intubation in the operating room, remifentanil, vs neuromuscular blockers, did not meet the criterion for noninferiority w regard to successful intubation on first attempt w/o major complications. https://t.co/ENvKxI7Oef
— JAMA (@JAMA_current) January 3, 2023