Critical Care
Case series of 18 male adults aged 50 years or younger with acute ischemic stroke during the convalescent phase of asymptomatic Covid-19
23 Apr, 2021 | 08:39h | UTC
Commentary on Twitter
A 💥🆕 case series highlights that adults 50 years or younger with asymptomatic COVID-19 infection diagnosed by positive SARS-CoV-2 serological test result may present with ischemic stroke during the convalescent phase of the infection
https://t.co/BVlo7Z1hgn @JAMANetworkOpen— Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 (@ABsteward) April 22, 2021
Covid-19: More data on the increased risks to pregnant women and their newborn infants
23 Apr, 2021 | 08:44h | UTCEditorial: COVID-19 in Pregnant Women and Their Newborn Infants
Commentaries: Pregnant women with COVID-19 face high mortality rate – University of Washington School of Medicine AND Covid-19 raises risks for expectant mothers and babies, study says – CNN
Commentary on Twitter
18 country study in >2000 pregnant women with and without #COVID19 shows higher complication and death rates in symptomatic, but not asymptomatic, women with COVID-19. Their babies were at greater risk of neonatal complications, mainly due to preterm birth https://t.co/mRl8OOIMsz
— JAMA Pediatrics (@JAMAPediatrics) April 22, 2021
Perioperative hemodynamic optimization: from guidelines to implementation—an experts’ opinion paper
23 Apr, 2021 | 08:21h | UTC
New-Generation Antibiotics for Treatment of Gram-Positive Infections: A Review with Focus on Endocarditis and Osteomyelitis
23 Apr, 2021 | 08:06h | UTC
An Update on Eight “New” Antibiotics against Multidrug-Resistant Gram-Negative Bacteria
23 Apr, 2021 | 08:05h | UTC
Review: Oral Antiplatelet Therapy After Acute Coronary Syndrome
22 Apr, 2021 | 08:22h | UTCOral Antiplatelet Therapy After Acute Coronary Syndrome: A Review – JAMA (free for a limited period)
Audio Clinical Review: Dual Antiplatelet Therapy After Acute Coronary Syndrome – JAMA
Systematic review: Venoarterial Extracorporeal Membrane Oxygenation in Massive Pulmonary Embolism-Related Cardiac Arrest
22 Apr, 2021 | 08:18h | UTCSummary: VA ECMO for Massive PE + Cardiac Arrest – Journal Feed
ISTH Interim Guidance for the Diagnosis and Treatment on Vaccine Induced Immune Thrombotic Thrombocytopenia
21 Apr, 2021 | 07:11h | UTCSee also: Diagnostic Flow Chart
Commentary on Twitter
The ISTH has released interim guidance on vaccine-induced immune thrombotic thrombocytopenia (#VITT) to inform the management of suspected thrombosis in subjects who have recently received the AstraZeneca or Johnson & Johnson vaccine. https://t.co/qqtQtpywaf pic.twitter.com/wNmjNNDs4z
— ISTH (@isth) April 20, 2021
Systematic review: Thrombolytic therapy for acute massive or submassive pulmonary embolism
21 Apr, 2021 | 06:20h | UTCThrombolytic therapy for pulmonary embolism – Cochrane Library
Summary: Drugs to dissolve pulmonary embolism (blood clot in the lungs) – Cochrane Library
Review: Dosing Fluids in Early Septic Shock
21 Apr, 2021 | 06:19h | UTCDosing Fluids in Early Septic Shock – CHEST
COVID-19 Vaccine Janssen: EMA finds possible link to very rare cases of unusual blood clots with low blood platelets
21 Apr, 2021 | 07:07h | UTCCommentary: Johnson & Johnson vaccine: EU regulator says blood clot very rare side effect – BBC
Commentary on Twitter
https://twitter.com/hildabast/status/1384535676482297865
Vaccine-induced Immune Thrombotic Thrombocytopenia: Frequently Asked Questions
21 Apr, 2021 | 07:09h | UTC
M-A: Corticosteroids in COVID-19 and non-COVID-19 ARDS
20 Apr, 2021 | 06:11h | UTC
Guideline Synopsis: Management of Acute Coronary Syndromes in Patients Without Persistent ST-Segment Elevation
21 Apr, 2021 | 06:41h | UTCManagement of Acute Coronary Syndromes in Patients Without Persistent ST-Segment Elevation – JAMA (free for a limited period)
Original guideline: #ESCCongress – 2020 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation AND Summary: The ‘Ten Commandments’ for the 2020 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation – European Heart Journal
Outcome of acute kidney injury: how to make a difference?
20 Apr, 2021 | 05:26h | UTCOutcome of acute kidney injury: how to make a difference? – Annals of Intensive Care
RCT: No benefit from second intravenous immunoglobulin dose in patients with Guillain-Barré syndrome with poor prognosis
18 Apr, 2021 | 21:21h | UTCSecond intravenous immunoglobulin dose in patients with Guillain-Barré syndrome with poor prognosis (SID-GBS): a double-blind, randomised, placebo-controlled trial – The Lancet Neurology (link to abstract – $ for full-text)
Hemodialysis Emergencies: Core Curriculum 2021
16 Apr, 2021 | 06:13h | UTCHemodialysis Emergencies: Core Curriculum 2021 – American Journal of Kidney Diseases
Commentary on Twitter
Hemodialysis Emergencies: Core Curriculum 2021https://t.co/BOQrsABOU3 (FREE)@KeikoGNeph @Mike_J_Choi @MedStarGUH #Hemodialysis pic.twitter.com/KYZRCqm5OA
— AJKD (@AJKDonline) March 26, 2021
Advances in Clinical Cardiology 2020: A Summary of Key Clinical Trials
16 Apr, 2021 | 06:14h | UTCAdvances in Clinical Cardiology 2020: A Summary of Key Clinical Trials – Advances in Therapy
Evolving changes in mortality of 13,301 critically ill adult patients with COVID-19 over 8 months
16 Apr, 2021 | 06:35h | UTC
Commentary on Twitter
Our paper on covid-19 pandemic trends in the first 8 months in the pandemic at @yourICM. Patients are getting younger, less frail, and mortality decreased over time. Very poor outcomes for elder frail patients. https://t.co/DHJvr22zFl
— Fernando Zampieri (@f_g_zampieri) April 14, 2021
M-A: Treatment with hydroxychloroquine is associated with increased mortality in COVID-19 patients
16 Apr, 2021 | 06:30h | UTC
Commentaries on Twitter
The use of hydroxychloroquine in COVID19 will be remembered as one of the worst examples of medicine going against its core principle:
First Do No Harm. https://t.co/PGq4D5pJ1H— Maurizio Cecconi (@DrMCecconi) April 15, 2021
What collaboration can achieve
Just out in @NatureComms our meta-analysis of 14 unpublished & 14 published RCTs on Hydroxychloroquine/ Choloroquine
Thanks so much to the great team – and special thanks for rapidly sharing the data of unpublished trials!https://t.co/Dg1DmAx1Kq
— Lars G. Hemkens (@LGHemkens) April 15, 2021
Were pregnant women more affected by COVID-19 in the second wave of the pandemic?
16 Apr, 2021 | 06:24h | UTCWere pregnant women more affected by COVID-19 in the second wave of the pandemic? – The Lancet
Case Report: Thrombotic Thrombocytopenia after Johnson & Johnson Vaccine
15 Apr, 2021 | 07:02h | UTCThrombotic Thrombocytopenia after Ad26.COV2.S Vaccination – New England Journal of Medicine
Related: U.S. regulators pause Johnson & Johnson vaccine rollout over rare (1 in a million) cases of blood clots AND 4 Things to Know About the J&J Covid Vaccine Pause – Kaiser Health News AND Why Johnson & Johnson shots were paused — and why that’s so confusing – Vox AND Is it the adenovirus vaccine technology, used by AstraZeneca and Johnson & Johnson, causing blood clots? There’s no evidence yet – The Conversation
New studies suggest SARS-CoV-2 variant B.1.1.7 is not more deadly, just more transmissible
14 Apr, 2021 | 02:12h | UTCCommentaries: Expert reaction to two papers looking at the transmissibility and severity of the B.1.1.7 variant – Science Media Centre AND UK coronavirus variant not more deadly, just spreads more easily, studies find – LiveScience
Study: Protocoled time-limited trials among critically ill patients with advanced medical illnesses were associated with reduction of nonbeneficial ICU treatments
13 Apr, 2021 | 05:16h | UTCEvaluation of Time-Limited Trials Among Critically Ill Patients With Advanced Medical Illnesses and Reduction of Nonbeneficial ICU Treatments – JAMA Internal Medicine (free for a limited period)
Commentary: Time-Limited Trials and Potentially Nonbeneficial Treatment in the ICU—Willing to Wait for It – JAMA Internal Medicine AND Time-limited trials may decrease the length of stay of critically ill patients in the intensive care unit – 2 Minute Medicine
Author interview: Time-Limited Trials Among Patients With Advanced Illness to Reduce Nonbeneficial ICU Treatments
Related review: Time-limited trial of intensive care treatment: an overview of current literature – Intensive Care Medicine
IDSA Guidance on the Treatment of ESBL Enterobacterales, Carbapenem-Resistant Enterobacterales, and Pseudomonas
13 Apr, 2021 | 05:11h | UTC