Critical Care | Page 23 of 78 | Links Medicus Content Curation & Alerts in Medicine

RCT | NIV is superior to high-flow nasal cannula to prevent reintubation in patients at high risk for extubation failure.

21 Nov, 2022 | 14:41h | UTC

Effect of postextubation noninvasive ventilation with active humidification vs high-flow nasal cannula on reintubation in patients at very high risk for extubation failure: a randomized trial – Intensive Care Medicine (free for a limited period)

Commentary on Twitter

NIV + active humidification vs HFNC in adult critically ill pts at very high-risk for extubation failure, RCT in ?? ICUs: noninvasive ventilation superior to high-flow nasal cannula O2
➡️ reintubation required in 23.3% pts receiving NIV vs 38.8% if HFNC
? https://t.co/2mNTf3PYEF pic.twitter.com/Fp2GtZpcLx

— Intensive Care Medicine (@yourICM) November 19, 2022

International guidelines and consensus on the use of lung ultrasound.

21 Nov, 2022 | 14:30h | UTC

New International Guidelines and Consensus on the Use of Lung Ultrasound – Journal of Ultrasound Medicine

Review | Penetrating brain injury: ethical quandaries in the trauma bay and beyond.

21 Nov, 2022 | 14:25h | UTC

Review Paper on Penetrating Brain Injury: Ethical Quandaries in the Trauma Bay and Beyond – Annals of Surgery (free for a limited period)

Portopulmonary hypertension: current developments and future perspectives.

21 Nov, 2022 | 14:20h | UTC

Portopulmonary hypertension: Current developments and future perspectives – Liver Research

Pulmonary complications of hepatic diseases – World Journal of Gastroenterology 

Pulmonary Vascular Complications of Liver Disease – American Journal of Respiratory and Critical Care Medicine

M-A | Lower vs. higher exposure to vasopressor therapy in vasodilatory hypotension.

21 Nov, 2022 | 14:16h | UTC

Lower Versus Higher Exposure to Vasopressor Therapy in Vasodilatory Hypotension: A Systematic Review With Meta-Analysis – Critical Care Medicine

Epidemiology of ICU-onset bloodstream infection: prevalence, pathogens, and risk factors among 150,948 ICU patients.

21 Nov, 2022 | 14:14h | UTC

Epidemiology of ICU-Onset Bloodstream Infection: Prevalence, Pathogens, and Risk Factors Among 150,948 ICU Patients at 85 U.S. Hospitals* – Critical Care Medicine

Review | Complications associated with venovenous extracorporeal membrane oxygenation—what can go wrong?

21 Nov, 2022 | 14:12h | UTC

Complications Associated With Venovenous Extracorporeal Membrane Oxygenation—What Can Go Wrong? – Critical Care Medicine

M-A | Prophylactic platelet transfusions vs. no prophylaxis in hospitalized patients with thrombocytopenia.

21 Nov, 2022 | 13:59h | UTC

Prophylactic platelet transfusions versus no prophylaxis in hospitalized patients with thrombocytopenia: A systematic review with meta-analysis – Transfusion

ISPD peritonitis guideline recommendations: 2022 update on prevention and treatment.

18 Nov, 2022 | 13:23h | UTC

ISPD peritonitis guideline recommendations: 2022 update on prevention and treatment – Peritoneal Dialysis International

M-A | High-flow nasal cannula vs. non-invasive ventilation for acute hypercapnic respiratory failure in adults.

17 Nov, 2022 | 12:25h | UTC

High-flow nasal cannula versus non-invasive ventilation for acute hypercapnic respiratory failure in adults: a systematic review and meta-analysis of randomized trials – Critical Care

M-A | Mechanical thrombectomy in acute basilar artery stroke.

17 Nov, 2022 | 12:13h | UTC

Mechanical thrombectomy in acute basilar artery stroke: a systematic review and Meta-analysis of randomized controlled trials – BMC Neurology

RCTs | Thrombectomy improved recovery in basilar artery stroke but increased procedural complications and hemorrhages.

Registry-based cohort study: Endovascular treatment vs. best medical management in acute basilar artery occlusion strokes.

RCT: Endovascular therapy for stroke due to basilar-artery occlusion – “endovascular therapy and medical therapy did not differ significantly with respect to a favorable functional outcome”.

Commentary on Twitter

https://twitter.com/drjkwan/status/1590403041840467969

M-A | Comparative accuracy of biomarkers for predicting hospital-acquired acute kidney injury.

17 Nov, 2022 | 12:09h | UTC

Comparative accuracy of biomarkers for the prediction of hospital-acquired acute kidney injury: a systematic review and meta-analysis – Critical Care

Review | POCUS for aortic dissection in the clinical presentation of ischemic stroke.

17 Nov, 2022 | 12:08h | UTC

POCUS for aortic dissection in the clinical presentation of ischemic stroke – emDocs

Editorial | Agitated patients in the intensive care unit: guidelines for causal rather than symptomatic treatment are warranted.

16 Nov, 2022 | 13:37h | UTC

Agitated Patients in the Intensive Care Unit: Guidelines for Causal Rather Than Symptomatic Treatment are Warranted – Journal of Intensive Care Medicine

Mineralocorticoid dysfunction during critical illness: a review of the evidence.

16 Nov, 2022 | 13:36h | UTC

Mineralocorticoid Dysfunction during Critical Illness: A Review of the Evidence – Anesthesiology

Commentary on Twitter

https://twitter.com/_Anesthesiology/status/1559925866892779520

Guideline | Peri-operative management of neuromuscular blockade.

16 Nov, 2022 | 13:38h | UTC

Peri-operative management of neuromuscular blockade: A guideline from the European Society of Anaesthesiology and Intensive Care – European Journal of Anaesthesiology

Guideline | Management of hyperosmolar hyperglycemic state in adults.

15 Nov, 2022 | 13:03h | UTC

Management of Hyperosmolar Hyperglycaemic State (HHS) in Adults: An updated guideline from the Joint British Diabetes Societies (JBDS) for Inpatient Care Group – Diabetic Medicine

RCT | Early routine use of ECMO fails to improve outcomes in patients with cardiogenic shock.

11 Nov, 2022 | 14:01h | UTC

Extracorporeal Membrane Oxygenation in the Therapy of Cardiogenic Shock: Results of the ECMO-CS Randomized Clinical Trial – Circulation

Commentaries:

Early use of ECMO devices to support adults with cardiogenic shock did not improve clinical outcomes – News Medical/American Heart Association

Early ECMO No Better Than Watch-and-Wait Approach in Cardiogenic Shock – TCTMD

Immediate Use of ECMO Did Not Improve Outcomes in Patients with Cardiogenic Shock – HCP Live

Commentary on Twitter

#OriginalResearch simpub #AHA2022: In this #RCT immediate implementation of VA-ECMO in patients with cardiogenic shock did not improve clinical outcomes compared with an early conservative strategy which allowed downstream use of… #CIRCAHA22 #AHAJournals https://t.co/03qVyC0Vgl pic.twitter.com/WRNDsAZfpD

— Circulation (@CircAHA) November 6, 2022

SR | Not enough evidence for routine use of antifibrinolytic therapy (e.g., tranexamic acid) in aneurysmal subarachnoid hemorrhage.

11 Nov, 2022 | 13:50h | UTC

Antifibrinolytic therapy for aneurysmal subarachnoid haemorrhage – Cochrane Library

RCT | No benefit from a model-informed precision dosing of beta-lactam antibiotics and ciprofloxacin in critically ill patients.

11 Nov, 2022 | 13:46h | UTC

Model-informed precision dosing of beta-lactam antibiotics and ciprofloxacin in critically ill patients: a multicentre randomised clinical trial – Intensive Care Medicine

Commentary on Twitter

Individualising beta-lactam ABTs/ciprofoxacin therapy in #ICU using model-informed precision dosing vs standard dosing, multicentre ?? RCT
No evidence for clinical effect of MIPD on LOS or other secondary outcomes in critically ill pts#FOAMcc @yourICM
?️https://t.co/6HzLBBnFdU pic.twitter.com/uErsHNAV5p

— Intensive Care Medicine (@yourICM) November 9, 2022

Review | Diagnosis of cardiac surgery-associated acute kidney injury.

10 Nov, 2022 | 13:27h | UTC

Diagnosis of Cardiac Surgery-Associated Acute Kidney Injury: State of the Art and Perspectives – Journal of Clinical Medicine

Clinical practice update for management of acute kidney injury associated with cardiac surgery.

CSA-AKI: Incidence, Epidemiology, Clinical Outcomes, and Economic Impact – Journal of Clinical Medicine

M-A | Strategies for post–cardiac surgery acute kidney injury prevention.

9 Nov, 2022 | 12:19h | UTC

Strategies for post–cardiac surgery acute kidney injury prevention: A network meta-analysis of randomized controlled trials – Frontiers in Cardiovascular Medicine

M-A | Point-of-care ultrasound evaluation for patients with acute onset dyspnea.

9 Nov, 2022 | 12:14h | UTC

Point-of-care ultrasound improves clinical outcomes in patients with acute onset dyspnea: a systematic review and meta-analysis – Internal and Emergency Medicine

RCT | New defibrillation strategies increased the rates of survival to hospital discharge in patients with refractory ventricular fibrillation.

8 Nov, 2022 | 12:27h | UTC

Defibrillation Strategies for Refractory Ventricular Fibrillation – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: “Double shock” from two defibrillators could save more lives – Heart & Stroke

Commentary on Twitter

In a trial involving patients with refractory ventricular fibrillation, double sequential external defibrillation or vector-change defibrillation improved survival as compared with standard defibrillation. #AHA22 https://t.co/2l2t9iGnwq pic.twitter.com/SzVU93OsrX

— NEJM (@NEJM) November 6, 2022