Clinical Pathology
Perspective | Should ‘daily labs’ be a quality priority in hospital medicine?
5 Dec, 2022 | 00:07h | UTCEditorial: Laboratory stewardship should be a priority in every hospital – Cleveland Clinic Journal of Medicine
Study | In hypertensive disorders of pregnancy, the levels of angiogenic factors may stratify the risk of severe preeclampsia.
10 Nov, 2022 | 14:11h | UTCCirculating Angiogenic Factor Levels in Hypertensive Disorders of Pregnancy – NEJM Evidence
Commentary on Twitter
This study measured the ratio of serum soluble fms-like tyrosine kinase (sFlt-1) to placental growth factor (PIGF) in pregnant pts hospitalized with HTN. An sFLT-1:PIGF ratio ≥ 40 stratified the risk of progressing to severe pre-eclampsia within 2 wks. https://t.co/H0uSHT2bN7 pic.twitter.com/ZKRvHsqLA4
— NEJM Evidence (@NEJMEvidence) November 9, 2022
Recommendations for laboratory testing of patients with acute myeloid leukemia.
25 Oct, 2022 | 13:21h | UTC
Position Statement | Use of biomarkers for the management of heart failure and acute coronary syndrome.
17 Oct, 2022 | 12:34h | UTC
Cohort Study | Analysis of clinical features, diagnostic tests, and biomarkers in patients with suspected Creutzfeldt-Jakob Disease.
15 Aug, 2022 | 11:47h | UTC
Commentary on Twitter
In patients with suspected Creutzfeldt-Jakob disease, CSF RT-QuIC, CSF T-tau, and stereotyped MRI anomalies were associated with diagnosis; myoclonus, stereotyped EEG anomalies, and CSF protein 14-3-3 were less helpful. #CohortStudy https://t.co/w3iaHMj3co
— JAMA Network Open (@JAMANetworkOpen) August 3, 2022
M-A | Diagnostic accuracy of urinary antigen tests for pneumococcal pneumonia among patients with acute respiratory failure suspected pneumonia.
12 Aug, 2022 | 14:28h | UTC
Real-time monitoring of blood parameters in the intensive care unit: state-of-the-art and perspectives.
12 Aug, 2022 | 14:14h | UTC
Diagnostic Test Interpretation | Serum Cystatin C for estimation of glomerular filtration rate.
9 Aug, 2022 | 12:52h | UTCSerum Cystatin C for Estimation of GFR – JAMA (free for a limited period)
Commentary on Twitter
An 80-year-old man with #type2diabetes and #hypertension was referred to the nephrology clinic for assessment of persistent hyperkalemia despite discontinuation of his ACE inhibitor. #JAMADiagnosticTestInterpretation https://t.co/kxg0yHeGUr
— JAMA (@JAMA_current) August 8, 2022
Systematic Review | Rapid, point‐of‐care antigen tests for diagnosis of SARS‐CoV‐2 infection.
29 Jul, 2022 | 12:39h | UTCRapid, point‐of‐care antigen tests for diagnosis of SARS‐CoV‐2 infection – Cochrane Library
Summary: How accurate are rapid antigen tests for diagnosing COVID-19? – Cochrane Library
Development and validation of a decision support tool for the diagnosis of acute heart failure: systematic review, meta-analysis, and modelling study.
22 Jul, 2022 | 11:18h | UTC
Commentary from the author on Twitter
In an international collaborative analysis, we developed a decision-support tool (CoDE-HF) that rules-in and rules-out acute heart failure more accurately than any approach using NT-proBNP thresholds alone- published today @bmj_latest https://t.co/JtPBEzcGqu pic.twitter.com/bCo9Xlzt5b
— Ken Lee (@KuanKenLee) June 13, 2022
Under a http://creativecommons.org/licenses/by/4.0/ license
High-sensitivity cardiac troponin and the 2021 AHA/ACC Guidelines for the evaluation and diagnosis of acute chest pain.
20 Jul, 2022 | 12:29h | UTCHigh-Sensitivity Cardiac Troponin and the 2021 AHA/ACC/ASE/CHEST/SAEM/SCCT/SCMR Guidelines for the Evaluation and Diagnosis of Acute Chest Pain – Circulation (free for a limited period)
Commentary on Twitter
#Primer HS Cardiac Troponin & Guidelines for Evaluation and Diagnosis of Acute Check Pain #AHAJournals https://t.co/avcm6LEbgb pic.twitter.com/zs8yRe6u1y
— Circulation (@CircAHA) July 13, 2022
Using circulating tumor DNA in colorectal cancer: current and evolving practices.
18 Jul, 2022 | 10:51h | UTC
Guidelines on germline testing for urologic tumor syndromes.
15 Jul, 2022 | 12:49h | UTCGuidelines on Germline Testing for Urologic Tumor Syndromes – European Urology Focus
ESMO recommendations on the use of circulating tumor DNA assays for patients with cancer.
13 Jul, 2022 | 11:38h | UTC
Genetic testing in prostate cancer management: considerations informing primary care.
13 Jul, 2022 | 11:25h | UTC
Modern developments in germline pharmacogenomics for oncology prescribing.
13 Jul, 2022 | 11:21h | UTC
Review | The promise of precision medicine in rheumatology.
12 Jul, 2022 | 12:38h | UTCThe promise of precision medicine in rheumatology – Nature Reviews Rheumatology
Commentary on Twitter
A Review in @NatureMedicine discusses recent efforts to dissect cellular and molecular heterogeneity across multiple systemic autoimmune rheumatic diseases and future directions for implementing stratification approaches for SARD treatment. https://t.co/5EGTkQjasR pic.twitter.com/NAgbnyU96O
— Nature Portfolio (@NaturePortfolio) July 8, 2022
Guideline Synopsis | Evaluation and diagnosis of chest pain.
4 Jul, 2022 | 12:49h | UTCEvaluation and Diagnosis of Chest Pain – JAMA (free for a limited period)
Original Guideline:
News Release: First-Ever Guideline Focused Solely on Chest Pain Evaluation, Diagnosis Released
Guideline Hub: Guideline for the Evaluation and Diagnosis of Chest Pain
Key Points: 2021 AHA/ACC Chest Pain Guideline – American College of Cardiology
Commentary: New Chest Pain Guidelines Out at Last: Most Tests Have a Role – TCTMD
Editorial | Circulating tumor cell burden as a component of staging in multiple myeloma: ready for prime time?
4 Jul, 2022 | 11:48h | UTCOriginal Studies:
Cohort Study: B‐Type Natriuretic Peptide and long‐term cardiovascular mortality in patients with coronary heart disease.
1 Jul, 2022 | 11:04h | UTC
ASCO Guideline Update: Biomarkers for systemic therapy in metastatic breast cancer.
29 Jun, 2022 | 11:40h | UTC
Commentary on Twitter
‼️ ? @ASCO guideline update published in #JCO by @lynnhenrymd et al: Biomarkers for #SystemicTherapy in Metastatic #BreastCancer ➡️ https://t.co/qAzT9WNKTF #bcsm #biomarkers @AngieDemichele pic.twitter.com/3WtAt8TK5w
— Journal of Clinical Oncology (@JCO_ASCO) June 27, 2022
Cohort Study: Association of gamma-glutamyltransferase levels with total mortality, liver-related and cardiovascular outcomes.
20 Jun, 2022 | 10:36h | UTC
Commentary on Twitter
Still remember working on this in 2019 but it's out today!
Gamma-GT level has a strong association with mortality outcomes and could add to the prediction of CV mortality
https://t.co/0lzqGfgiGc pic.twitter.com/C8tSZLWlI2— Fred Ho (@fredho42) May 13, 2022
Under a CC BY-NC-ND 4.0 license