Chest Medicine
The UK has approved a COVID vaccine — but scientists still have many questions. One of them is if the vaccines will prevent the transmission of the disease
7 Dec, 2020 | 00:52h | UTCThe UK has approved a COVID vaccine — here’s what scientists now want to know – Nature
Study in Germany comparing regions with vs. without mask mandates concluded that 20 d after becoming mandatory, face masks reduced new Covid-19 infections by around 45%
7 Dec, 2020 | 00:46h | UTC
Randomized trial: High-dose influenza vaccine shows no additional benefit for heart disease patients
7 Dec, 2020 | 00:44h | UTCEditorial: Influenza Vaccine for Patients With High-risk Cardiovascular Disease
Commentary: High-dose influenza vaccine shows no additional benefit for heart disease patients – NIH News Releases
Commentary on Twitter
In patients w high-risk CVD, high-dose trivalent influenza vaccine, vs standard-dose quadrivalent vaccine, did not significantly reduce all-cause mortality or cardiopulmonary hospitalizations https://t.co/I3XygBajQL
— JAMA (@JAMA_current) December 4, 2020
Meta-analysis reinforces the safety of betablockers in patients with COPD and cardiovascular disease
6 Dec, 2020 | 23:30h | UTCCommentary: Beta-Blockers in Patients With COPD and CVD – American College of Cardiology
Managing Asthma in Adolescents and Adults: 2020 Asthma Guideline Update From the National Asthma Education and Prevention Program
4 Dec, 2020 | 08:33h | UTCEditorial: Evolving Strategies for Long-term Asthma Management – JAMA
Commentaries: New Asthma Guidelines Published in The Journal of Allergy and Clinical Immunology, an Official Journal of the AAAAI – American Academy of Allergy, Asthma & Immunology AND New updates to federal guidelines revamp asthma management – NHLBI News
New WHO Guidance on masks for the public and health workers in the context of COVID-19
4 Dec, 2020 | 08:24h | UTCMask use in the context of COVID-19 – World Health Organization
Commentaries: WHO fine-tunes advice on COVID masks for public, health workers – Reuters AND WHO updates mask advice, recommending they be worn in indoor, poorly ventilated areas – CBC
Commentary on Twitter
.@WHO has tightened its guidance on face masks, recommending that where COVID-19 is spreading, masks be worn by everyone in healthcare settings, indoor low ventilated areas & outdoors when a distance of 3 ft from others cannot be maintained. #MaskUpAmerica https://t.co/dJUJ2syDMN
— IDSA (@IDSAInfo) December 3, 2020
Why the CDC changed its Covid-19 quarantine guidelines
4 Dec, 2020 | 08:18h | UTCWhy the CDC changed its Covid-19 quarantine guidelines – Vox
CDC Guideline: Duration of Isolation and Precautions for Adults with COVID-19 – Centers for Disease Control and Prevention
Moderna vaccine: Antibody levels persist for at least 4 months
4 Dec, 2020 | 08:16h | UTCDurability of Responses after SARS-CoV-2 mRNA-1273 Vaccination – New England Journal of Medicine
UK becomes first country to authorize Pfizer/BioNTech’s Covid-19 vaccine, first shots roll out next week
3 Dec, 2020 | 08:44h | UTCPress release: UK medicines regulator gives approval for first UK COVID-19 vaccine – Medicines and Healthcare products Regulatory Agency
See also: Covid-19: Pfizer/BioNTech vaccine judged safe for use in UK – BBC AND Expert reaction to news that the MHRA has approved the Pfizer/BioNTech COVID-19 vaccine for mass UK roll out – Science Media Centre AND UK approves Pfizer/BioNTech Covid vaccine for rollout next week – The Guardian
WHO Solidarity Trial: Remdesivir, hydroxychloroquine, lopinavir, and interferon regimens had little or no effect on hospitalized patients with Covid-19
3 Dec, 2020 | 08:47h | UTCAudio Interview: Caring for Hospitalized Patients with Covid-19
Commentary on Twitter (thread – click for more)
The biggest multinational pandemic randomised trial #SOLIDARITYtrial published in the New England Journal of Medicine. https://t.co/VbpbpziFwm
WHO, trial leaders, numerous countries, hospitals, doctors, nurses, patients & many others are to be congratulated!
Key results 👇🏾 1/5 pic.twitter.com/Xe9K6EfUpc
— Kari Tikkinen (@KariTikkinen) December 2, 2020
Review: Cytokine Storm
3 Dec, 2020 | 08:46h | UTCCytokine Storm – New England Journal of Medicine
Commentary on Twitter
Cytokine storm is a prominent feature in severe #COVID19. This new @NEJM review on it is as good as it gets. By @DavidFajgenbaum @carlhjune @PennMedicine https://t.co/a4qE7xGR58 pic.twitter.com/Ul1HrnL8Ve
— Eric Topol (@EricTopol) December 2, 2020
CDC to shorten COVID-19 quarantine to 10 days, 7 with test
3 Dec, 2020 | 08:40h | UTCCDC to shorten COVID-19 quarantine to 10 days, 7 with test – Associated Press
Commentary: CDC Shortens Its COVID-19 Quarantine Recommendations – NPR
Case series: Shedding of viable SARS-CoV-2 after immunosuppressive therapy for cancer
2 Dec, 2020 | 07:31h | UTC
What’s the difference between viral shedding and reinfection with COVID-19?
2 Dec, 2020 | 07:29h | UTCWhat’s the difference between viral shedding and reinfection with COVID-19? – The Conversation
Systematic review: Outdoor transmission of SARS-CoV-2 and other respiratory viruses. “The odds of indoor transmission was very high compared to outdoors (18.7 times)”
2 Dec, 2020 | 07:19h | UTC
Commentary on Twitter
Outdoor Transmission of SARS-CoV-2 and Other Respiratory Viruses, a Systematic Review https://t.co/lmWQNgpIfd Existing evidence supports the wide-held belief that the the risk of #SARSCoV2 transmission is lower outdoors (< 10%).
— Carlos del Rio (@CarlosdelRio7) December 1, 2020
NICE COVID-19 guideline: Prevention of thromboembolism in patients with COVID-19. “For patients who are having advanced respiratory support: consider increasing pharmacological VTE prophylaxis to an intermediate dose”
1 Dec, 2020 | 08:19h | UTC
Moderna released more Covid-19 vaccine results. They’re very encouraging.
1 Dec, 2020 | 08:15h | UTCModerna released more Covid-19 vaccine results. They’re very encouraging. – Vox
Commentaries: ‘Absolutely remarkable’: No one who got Moderna’s vaccine in trial developed severe COVID-19 – Science AND Moderna to submit Covid-19 vaccine to FDA as full results show 94% efficacy – STAT AND More Good News For Moderna’s COVID-19 Vaccine Candidate – NPR AND Moderna to seek emergency authorization for COVID-19 vaccine – CIDRAP
Commentary on Twitter
Moderna has announced the final results of the 30,000-person efficacy trial for its #COVID19 vaccine candidate, reporting that the vaccine had 100% efficacy against severe disease. https://t.co/Cgg0I5nv9r
— News from Science (@NewsfromScience) November 30, 2020
Opinion: Pfizer and Moderna’s “95% effective” vaccines—let’s be cautious and first see the full data
1 Dec, 2020 | 08:13h | UTC
Colchicine to be investigated as a possible treatment for COVID-19 in the RECOVERY trial
1 Dec, 2020 | 08:08h | UTCCommentary: Gout drug Colchicine to be tested as COVID-19 treatment in UK trial – Reuters
Critically ill patients with COVID-19: A narrative review on prone position
1 Dec, 2020 | 08:07h | UTCCritically Ill Patients with COVID-19: A Narrative Review on Prone Position – Pulmonary Therapy
Report: SARS-CoV-2 setting-specific transmission rates. Households showed the highest transmission rates (21.1%). Asymptomatic infections do occur but much less efficiently than symptomatic infection.
30 Nov, 2020 | 01:01h | UTCFull report: SARS-CoV-2 setting-specific transmission rates: a systematic review and meta-analysis – Imperial College London
No evidence for increased transmissibility from mutations in SARS-CoV-2
30 Nov, 2020 | 01:06h | UTCCommentaries: Mutations not making coronavirus able to spread more rapidly -study – Reuters AND Covid-19 has NOT become more infectious: Study identifies almost 13,000 coronavirus mutations but none – including the dominant D614G strain – made it better at spreading – Daily Mail
Infection fatality rate of SARS-CoV2 in a super-spreading event in Germany estimated at 0.36%
30 Nov, 2020 | 01:02h | UTCInfection fatality rate of SARS-CoV2 in a super-spreading event in Germany – Nature Communications
Long Covid: Comprehensive health assessment three months after recovery from acute COVID-19 revealed problems in several health domains in a substantial number of patients
27 Nov, 2020 | 08:33h | UTC
An artificial intelligence algorithm can detect COVID-19 on chest radiographs with accuracy and speed
27 Nov, 2020 | 08:31h | UTCCommentaries: AI system bests radiologists in spotting COVID-19 in lungs – CIDRAP AND AI detects COVID-19 on chest x-rays with accuracy and speed – Northwestern University