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Chest Medicine (all articles)

CDC releases new ventilation guidelines for indoor environments to reduce Covid-19 risk

9 Dec, 2020 | 08:23h | UTC

CDC Releases New Ventilation Guidelines For Indoor Environments To Reduce Covid-19 Risk – Forbes

CDC Guideline: Ventilation

Related podcast: Air Handling Standards for Increasing the Safety of Indoor Spaces During the COVID-19 Pandemic – JAMA

 


Just published: AstraZeneca-Oxford Covid-19 vaccine shows moderate efficacy, but questions remain about the most effective dosing regimen

9 Dec, 2020 | 08:25h | UTC

Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK – The Lancet

Commentaries: Oxford COVID vaccine paper highlights lingering unknowns about results – Nature AND Detailed data on AstraZeneca-Oxford Covid-19 vaccine show it has moderate efficacy – STAT AND Oxford–AstraZeneca COVID-19 vaccine efficacy – The Lancet AND Oxford COVID-19 vaccine is safe and protects against disease, first published results from phase 3 trials – The Lancet AND Expert reaction to a study on the results of phase 3 human trials of the Oxford/AZ COVID-19 vaccine – Science Media Centre

 


“COVID-19: when are you most infectious?” This commentary from the authors of a recent meta-analysis highlights the findings that infectiousness peaks within the first 5 days of symptom onset

10 Dec, 2020 | 08:38h | UTC

COVID-19: when are you most infectious? – The Conversation

Original study and commentaries: Meta-analysis: SARSCoV2 most contagious within the first 5 days of symptom onset

 


Another randomized trial shows hydroxychloroquine is not effective as postexposure prophylaxis to prevent Covid-19

9 Dec, 2020 | 08:19h | UTC

Hydroxychloroquine as Postexposure Prophylaxis to Prevent Severe Acute Respiratory Syndrome Coronavirus 2 Infection: A Randomized Trial – Annals of Internal Medicine

Summary for patients: Summary for Patients: Postexposure Hydroxychloroquine Prophylaxis to Prevent SARS-CoV-2 Infection

 


If exposed to Covid-19, how long before you have symptoms? Median incubation is 5.1 days, and 97.5% of those who develop symptoms do so within 11.5 days of being exposed to the virus

8 Dec, 2020 | 08:06h | UTC

If Exposed To Covid-19 Coronavirus, How Long Before You Have Symptoms – Forbes

 


Opinion: “Get ready for vaccine false side effects”. When millions of people are vaccinated, naturally occurring health problems could be wrongly attributed to vaccines

8 Dec, 2020 | 07:55h | UTC

Get Ready for False Side Effects – Science Translational Medicine

 


First-of-its-kind African trial tests common drugs to prevent severe COVID-19. “Could cheap, widely available drugs prevent patients with mild illness from becoming severely sick?”

8 Dec, 2020 | 07:46h | UTC

First-of-its-kind African trial tests common drugs to prevent severe COVID-19 – Science

 


New CDC Guidance with 10 public health strategies to address high levels of community transmission of SARS-Cov-2, including universal use of face masks

7 Dec, 2020 | 01:10h | UTC

Summary of Guidance for Public Health Strategies to Address High Levels of Community Transmission of SARS-CoV-2 and Related Deaths, December 2020 – CDC Morbidity and Mortality Weekly Report

Commentaries: Masks are critical to stopping coronavirus spread, even at home, CDC says – CNN AND CDC recommends ‘universal’ use of face masks to prevent COVID-19 spread – UPI

 

Commentary on Twitter

 


Meta-analysis: Respiratory function post-infection by COVID-19. Altered diffusion capacity, restrictive pattern, and obstructive pattern were found in 39%, 15% and 7% of patients, respectively

7 Dec, 2020 | 01:04h | UTC

Respiratory function in patients post-infection by COVID-19: a systematic review and meta-analysis – Pulmonology

 

Commentary on Twitter

 


Myocardial injury in severe COVID-19 is similar to traditional ARDS. It is a function of baseline comorbidities, advanced age, and multisystem organ dysfunction

7 Dec, 2020 | 00:59h | UTC

Myocardial Injury in Severe COVID-19 Compared to Non-COVID Acute Respiratory Distress Syndrome – Circulation

Commentary: Myocardial Injury in Severe COVID-19 vs. ARDS – American College of Cardiology

 

Commentary on Twitter

 


The UK has approved a COVID vaccine — but scientists still have many questions. One of them is if the vaccines will prevent the transmission of the disease

7 Dec, 2020 | 00:52h | UTC

The UK has approved a COVID vaccine — here’s what scientists now want to know – Nature

 


Study in Germany comparing regions with vs. without mask mandates concluded that 20 d after becoming mandatory, face masks reduced new Covid-19 infections by around 45%

7 Dec, 2020 | 00:46h | UTC

Face masks considerably reduce COVID-19 cases in Germany – Proceedings of the National Academy of Sciences

 


Randomized trial: High-dose influenza vaccine shows no additional benefit for heart disease patients

7 Dec, 2020 | 00:44h | UTC

Effect of High-Dose Trivalent vs Standard-Dose Quadrivalent Influenza Vaccine on Mortality or Cardiopulmonary Hospitalization in Patients With High-risk Cardiovascular Disease: A Randomized Clinical Trial – JAMA

Editorial: Influenza Vaccine for Patients With High-risk Cardiovascular Disease

Commentary: High-dose influenza vaccine shows no additional benefit for heart disease patients – NIH News Releases

 

Commentary on Twitter

 


Meta-analysis reinforces the safety of betablockers in patients with COPD and cardiovascular disease

6 Dec, 2020 | 23:30h | UTC

Association of β-blocker use with survival and pulmonary function in patients with chronic obstructive pulmonary and cardiovascular disease: a systematic review and meta-analysis – European Heart Journal

Commentary: Beta-Blockers in Patients With COPD and CVD – American College of Cardiology

 


Managing Asthma in Adolescents and Adults: 2020 Asthma Guideline Update From the National Asthma Education and Prevention Program

4 Dec, 2020 | 08:33h | UTC

Managing Asthma in Adolescents and Adults2020 Asthma Guideline Update From the National Asthma Education and Prevention Program – JAMA

Full guideline: 2020 Focused Updates to the Asthma Management Guidelines: A Report from the National Asthma Education and Prevention Program Coordinating Committee Expert Panel Working Group – The Journal of Allergy & Clinical Immunology

Editorial: Evolving Strategies for Long-term Asthma Management – JAMA

Commentaries: New Asthma Guidelines Published in The Journal of Allergy and Clinical Immunology, an Official Journal of the AAAAI – American Academy of Allergy, Asthma & Immunology AND New updates to federal guidelines revamp asthma management – NHLBI News

 


New WHO Guidance on masks for the public and health workers in the context of COVID-19

4 Dec, 2020 | 08:24h | UTC

Mask use in the context of COVID-19 – World Health Organization

Commentaries: WHO fine-tunes advice on COVID masks for public, health workers – Reuters AND WHO updates mask advice, recommending they be worn in indoor, poorly ventilated areas – CBC

 

Commentary on Twitter

 


Why the CDC changed its Covid-19 quarantine guidelines

4 Dec, 2020 | 08:18h | UTC

Why the CDC changed its Covid-19 quarantine guidelines – Vox

CDC Guideline: Duration of Isolation and Precautions for Adults with COVID-19 – Centers for Disease Control and Prevention

 


Moderna vaccine: Antibody levels persist for at least 4 months

4 Dec, 2020 | 08:16h | UTC

Durability of Responses after SARS-CoV-2 mRNA-1273 Vaccination – New England Journal of Medicine

 


UK becomes first country to authorize Pfizer/BioNTech’s Covid-19 vaccine, first shots roll out next week

3 Dec, 2020 | 08:44h | UTC

UK becomes first country to authorize Pfizer/BioNTech’s Covid-19 vaccine, first shots roll out next week – CNN

Press release: UK medicines regulator gives approval for first UK COVID-19 vaccine – Medicines and Healthcare products Regulatory Agency

See also: Covid-19: Pfizer/BioNTech vaccine judged safe for use in UK – BBC AND Expert reaction to news that the MHRA has approved the Pfizer/BioNTech COVID-19 vaccine for mass UK roll out – Science Media Centre AND UK approves Pfizer/BioNTech Covid vaccine for rollout next week – The Guardian

 


WHO Solidarity Trial: Remdesivir, hydroxychloroquine, lopinavir, and interferon regimens had little or no effect on hospitalized patients with Covid-19

3 Dec, 2020 | 08:47h | UTC

Repurposed Antiviral Drugs for Covid-19 — Interim WHO Solidarity Trial Results – New England Journal of Medicine

Audio Interview: Caring for Hospitalized Patients with Covid-19

 

Commentary on Twitter (thread – click for more)

 


Review: Cytokine Storm

3 Dec, 2020 | 08:46h | UTC

Cytokine Storm – New England Journal of Medicine

 

Commentary on Twitter

 


CDC to shorten COVID-19 quarantine to 10 days, 7 with test

3 Dec, 2020 | 08:40h | UTC

CDC to shorten COVID-19 quarantine to 10 days, 7 with test – Associated Press

Commentary: CDC Shortens Its COVID-19 Quarantine Recommendations – NPR

 


Case series: Shedding of viable SARS-CoV-2 after immunosuppressive therapy for cancer

2 Dec, 2020 | 07:31h | UTC

Shedding of Viable SARS-CoV-2 after Immunosuppressive Therapy for Cancer – New England Journal of Medicine

 


What’s the difference between viral shedding and reinfection with COVID-19?

2 Dec, 2020 | 07:29h | UTC

What’s the difference between viral shedding and reinfection with COVID-19? – The Conversation

 


Systematic review: Outdoor transmission of SARS-CoV-2 and other respiratory viruses. “The odds of indoor transmission was very high compared to outdoors (18.7 times)”

2 Dec, 2020 | 07:19h | UTC

Outdoor Transmission of SARS-CoV-2 and Other Respiratory Viruses, a Systematic Review – The Journal of Infectious Diseases

 

Commentary on Twitter

 


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