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Chest Medicine

Study: Smoking is associated with a higher risk of hospitalization and mortality from COVID-19 in a dose-dependent manner

4 Mar, 2021 | 08:41h | UTC

Association of Smoking and Cumulative Pack-Year Exposure With COVID-19 Outcomes in the Cleveland Clinic COVID-19 Registry – JAMA Internal Medicine

Commentary: Heavy smokers have DOUBLE the risk of dying of COVID-19 – Daily Mail

 

RCT: Inspiratory muscle training with an electronic resistive loading device improves prolonged weaning outcomes

4 Mar, 2021 | 08:10h | UTC

Inspiratory Muscle Training With an Electronic Resistive Loading Device Improves Prolonged Weaning Outcomes in a Randomized Controlled Trial – Critical Care Medicine (link to abstract – $ for full-text)

 

Commentaries on Twitter

 

RCT: Following high-risk surgery, automated closed-loop oxygen administration promotes a higher time within range as compared to standard manual administration

4 Mar, 2021 | 08:05h | UTC

Automated closed-loop versus standard manual oxygen administration after major abdominal or thoracic surgery: an international multicentre randomised controlled study – European Heart Journal (link to abstract – $ for full-text)

 

NIH halts trial of COVID-19 convalescent plasma in emergency department patients with mild symptoms

3 Mar, 2021 | 08:55h | UTC

NIH halts trial of COVID-19 convalescent plasma in emergency department patients with mild symptoms – National Institutes of Health

 

WHO Guideline recommends against Hydroxychloroquine to prevent Covid-19

3 Mar, 2021 | 08:56h | UTC

A living WHO guideline on drugs to prevent covid-19 – The BMJ

See also: WHO Living guideline: Drugs to prevent COVID-19 – World Health Organization

Commentaries: WHO advises against hydroxychloroquine to curb COVID-19 – CIDRAP AND WHO panel issues strong advice against hydroxychloroquine for COVID-19 – Reuters

 

Commentary on Twitter

 

More transmissible and evasive SARS-CoV-2 variant growing rapidly in Brazil

3 Mar, 2021 | 08:53h | UTC

More transmissible and evasive SARS-CoV-2 variant growing rapidly in Brazil – Imperial College London

Original study (preprint): Genomics and epidemiology of a novel SARS-CoV-2 lineage in Manaus, Brazil

Commentaries: Covid Brazil variant ‘may spread more easily’ – BBC AND Brazil coronavirus variant: what is it and why is it a concern? An expert explains – The Conversation

 

Covid-19: Single dose of Pfizer and Oxford vaccines cuts risk of hospital admission by 80% in over 80s, data suggest

3 Mar, 2021 | 08:51h | UTC

Covid-19: Single dose of Pfizer and Oxford vaccines cuts risk of hospital admission by 80% in over 80s, data suggest – The BMJ

 

Commentary on Twitter

 

M-A: Global burden of influenza-associated lower respiratory tract infections and hospitalizations among adults

3 Mar, 2021 | 08:30h | UTC

Global burden of influenza-associated lower respiratory tract infections and hospitalizations among adults: A systematic review and meta-analysis – PLOS Medicine

 

The predicative clinical features associated with chronic cough that has a single underlying cause

3 Mar, 2021 | 08:14h | UTC

The Predicative Clinical Features Associated with Chronic Cough That Has a Single Underlying Cause – The Journal of Allergy and Clinical Immunology: In Practice

News release: Clinical features for indicating causes of chronic cough – American Academy of Allergy, Asthma & Immunology

 

Another study shows higher antibody titer responses to a single dose of mRNA vaccine among patients with previous COVID-19 infection

2 Mar, 2021 | 02:13h | UTC

Binding and Neutralization Antibody Titers After a Single Vaccine Dose in Health Care Workers Previously Infected With SARS-CoV-2 – JAMA

Related: Studies: Single dose of vaccine acts as ‘booster’ in those with prior COVID-19 infection (studies and commentary)

 

WHO: Roadmap to improve and ensure good indoor ventilation in the context of COVID-19

2 Mar, 2021 | 02:15h | UTC

Roadmap to improve and ensure good indoor ventilation in the context of COVID-19 – World Health Organization

 

Commentary on Twitter

 

Studies: Secondary infections in patients with severe COVID-19

2 Mar, 2021 | 02:05h | UTC

Secondary Infections in Patients with Severe COVID-19 – NEJM Journal Watch

Study 1: Nosocomial infections associated to COVID-19 in the intensive care unit: clinical characteristics and outcome – Intensive Care Medicine

Study 2: COVID-19 increased the risk of ICU-acquired bloodstream infections: a case–cohort study from the multicentric OUTCOMEREA network – Intensive Care Medicine

 

Scaling up COVID-19 rapid antigen tests: promises and challenges

2 Mar, 2021 | 02:09h | UTC

Scaling up COVID-19 rapid antigen tests: promises and challenges – The Lancet Infectious Diseases

 

Review: Cardiovascular biomarkers in patients with COVID-19

2 Mar, 2021 | 02:07h | UTC

Cardiovascular biomarkers in patients with COVID-19 – European Heart Journal. Acute Cardiovascular Care

 

Commentary on Twitter

 

Serious bradycardia and Remdesivir for COVID-19: a new safety concern

2 Mar, 2021 | 02:06h | UTC

Serious bradycardia and remdesivir for coronavirus 2019 (COVID-19): a new safety concerns – Clinical Microbiology and Infection

 

Commentary on Twitter

 

Systematic Review: Signs and symptoms to determine if a patient presenting in primary care or hospital outpatient settings has COVID‐19

2 Mar, 2021 | 01:54h | UTC

Signs and symptoms to determine if a patient presenting in primary care or hospital outpatient settings has COVID‐19 – Cochrane Library

Summary: Can symptoms and medical examination accurately diagnose COVID-19? – Cochrane Library

 

 

M-A: Treatment with convalescent plasma is not associated with better outcomes in patients with Covid-19

28 Feb, 2021 | 21:51h | UTC

Association of Convalescent Plasma Treatment With Clinical Outcomes in Patients With COVID-19: A Systematic Review and Meta-analysis – JAMA

Editorial: Emerging Lessons From COVID-19 for the US Clinical Research Enterprise

 

Commentary on Twitter

 

CDC Study: Suspected SARS-CoV-2 reinfections in a skilled nursing facility

28 Feb, 2021 | 21:55h | UTC

Suspected Recurrent SARS-CoV-2 Infections Among Residents of a Skilled Nursing Facility During a Second COVID-19 Outbreak — Kentucky, July–November 2020 – CDC Morbidity and Mortality Weekly Report

Commentaries: Possible SARS-CoV-2 Reinfection Described at Skilled Nursing Facility – HealthDay AND Reinfections could be more likely among those with a mild first case of COVID-19: case study – CTV News

 

Commentary on Twitter (thread – Click for more)

 

Short Review: SARS-CoV-2 Vaccines

28 Feb, 2021 | 21:52h | UTC

SARS-CoV-2 Vaccines – JAMA

Author interview: Coronavirus Vaccines—An Overview

 

 

Studies: Single dose of vaccine acts as ‘booster’ in those with prior COVID-19 infection

28 Feb, 2021 | 21:49h | UTC

Single dose of vaccine acts as ‘booster’ in those with prior COVID-19 infection – Imperial College London

Study 1: Antibody response to first BNT162b2 dose in previously SARS-CoV-2-infected individuals – The Lancet

Study 2: Effect of previous SARS-CoV-2 infection on humoral and T-cell responses to single-dose BNT162b2 vaccine – The Lancet

 

Commentary on Twitter (thread – click for more)

 

Identification of 3 clinical phenotypes with prognostic implications in patients admitted to hospital with COVID-19

28 Feb, 2021 | 21:45h | UTC

Identification and validation of clinical phenotypes with prognostic implications in patients admitted to hospital with COVID-19: a multicentre cohort study – The Lancet Infectious Diseases

Invited Commentary: Anticipating outcomes for patients with COVID-19 and identifying prognosis patterns

 

Commentary on Twitter

 

Spain to give just one vaccine dose to under 55-year olds who had COVID-19

28 Feb, 2021 | 21:47h | UTC

Spain to give just one vaccine dose to under 55-year olds who had COVID-19 – Reuters

Related: Is One Vaccine Dose Enough After COVID-19 Infection? – NIH Director’s Blog AND France’s health authority recommends single vaccine shot for people who have had COVID-19

 

Editorial | Twenty Lessons from 2020: With a Focus on the ICU Perspective

28 Feb, 2021 | 21:44h | UTC

Twenty Lessons from 2020: With a Focus on the ICU Perspective – ICU Management & Practice

 

2 Case Series and Guidance| Lymphadenopathy in COVID-19 Vaccine Recipients

28 Feb, 2021 | 21:42h | UTC

Case series: Lymphadenopathy in COVID-19 Vaccine Recipients: Diagnostic Dilemma in Oncology Patients – Radiology

Related case series in women without cancer: Coronavirus Disease (COVID-19) Vaccination Associated Axillary Adenopathy: Imaging Findings and Follow-Up Recommendations in 23 Women – American Journal of Roentgenology

Related guidance 1: Multidisciplinary Recommendations Regarding Post-Vaccine Adenopathy and Radiologic Imaging: Radiology Scientific Expert Panel – Radiology

Related guidance 2: Mitigating the Impact of Coronavirus Disease (COVID-19) Vaccinations on Patients Undergoing Breast Imaging Examinations: A Pragmatic Approach – American Journal of Roentgenology AND Commentary: What to do when a mammogram shows swollen lymph nodes in women just vaccinated for COVID – Massachusetts General Hospital

Commentary: COVID-19 vaccine affects imaging results, researchers warn – AuntMinnie (free registration required)

 

Improving lung health in low-income and middle-income countries: from challenges to solutions

28 Feb, 2021 | 21:23h | UTC

Improving lung health in low-income and middle-income countries: from challenges to solutions – The Lancet (free registration required)

 

Commentary on Twitter

 

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