Chest Medicine
Meta-Analysis: Risk of Pneumonitis and Pneumonia Associated With Immune Checkpoint Inhibitors for Solid Tumors
16 Feb, 2019 | 19:52h | UTCRelated: Severe Toxicity from Checkpoint Protein Inhibitors (free guidelines and reviews on the subject)
Australian Guideline for the Diagnosis and Management of Venous Thromboembolism
12 Feb, 2019 | 00:31h | UTCNews Release: New Guidelines for Venous Thromboembolism (free)
Related Guidelines: BTS Guideline: Outpatient Management of Pulmonary Embolism (free) AND ACEP Clinical Policy: Evaluation and Management of Suspected Acute Venous Thromboembolism (free) AND Evaluation of Patients With Suspected Acute Pulmonary Embolism: Best Practice Advice From the Clinical Guidelines Committee of the American College of Physicians (free) AND 2014 ESC Guidelines on the diagnosis and management of acute pulmonary embolism: The Task Force for the Diagnosis and Management of Acute Pulmonary Embolism of the European Society of Cardiology (ESC) (free)
Related Commentary on Twitter
https://twitter.com/theMJA/status/1094873925543092224
Observational Study: Antibiotics Provide No Benefit for Hospitalized Asthma Patients, Linked to Longer Hospital Stay
12 Feb, 2019 | 00:04h | UTCAssociation of Antibiotic Treatment With Outcomes in Patients Hospitalized for an Asthma Exacerbation Treated With Systemic Corticosteroids – JAMA Internal Medicine (link to abstract – $ for full-text)
Commentaries: Should Hospitalized Asthma Patients Receive Antibiotics? – MedicalResearch.com (free) AND No benefit of antibiotic treatment for hospitalised asthma patients – medwire News (free) AND Antibiotic therapy for asthma exacerbation associated with longer hospital stay – 2 Minute Medicine (free) AND Antibiotics Provide No Added Benefit in Severe Asthma Flares – ACEPNow (free)
Related Commentary on Twitter
“…although guidelines do not recommend #antibiotics for patients hospitalized with an #asthma exacerbation (unless [there are] clear signs of infection) 41% of patients receive #abx on day 1 of hospitalization." #FOAMed
Full story here: https://t.co/cLvpFgcmMZ pic.twitter.com/1x01e2awIb
— ACEP Members (@ACEPNow) February 8, 2019
NICE Guideline: Antimicrobial Prescribing for Acute Cough
11 Feb, 2019 | 00:20h | UTCCough (acute): antimicrobial prescribing – National Institute for Health and Care Excellence (free)
Infographic: 2-page visual summary of the recommendations (free PDF)
See also: NICE Antimicrobial prescribing guidelines (resource covering many common conditions) AND NICE Summary of antimicrobial prescribing guidance – managing common infections (free PDF)
Clinical Practice Guidelines for Diagnosis and Management of Cough
10 Feb, 2019 | 14:35h | UTCRelated Guideline: KAAACI Evidence-Based Clinical Practice Guidelines for Chronic Cough in Adults and Children in Korea – Allergy, Asthma & Immunology Research (free)
See also recently published CHEST guidelines on the management of cough in specific populations: Classification of Cough as a Symptom in Adults and Management Algorithms (free) AND Adult Outpatients With Acute Cough Due to Suspected Pneumonia or Influenza – CHEST Guideline and Expert Panel Report (free) AND Clinically Diagnosing Pertussis-associated Cough in Adults and Children (free) AND Pharmacologic and Nonpharmacologic Treatment for Acute Cough Associated With the Common Cold (free) AND Cough Due to TB and Other Chronic Infections (free) AND Chronic Cough Due to Gastroesophageal Reflux in Adults (free) AND Symptomatic Treatment of Cough Among Adult Patients With Lung Cancer (free) AND Cough in the athlete (free) AND Occupational and Environmental Contributions to Chronic Cough in Adults (free) AND Treatment of Unexplained Chronic Cough (free) AND Use of Management Pathways or Algorithms in Children With Chronic Cough (free) AND Management of Children With Chronic Wet Cough and Protracted Bacterial Bronchitis (free)
Expert Consensus on Diagnosis and Management of Severe Asthma
10 Feb, 2019 | 14:34h | UTCChinese expert consensus on diagnosis and management of severe asthma – Journal of Thoracic Disease (free)
Related Guidelines: Recognition and management of severe asthma: A Canadian Thoracic Society position statement (free) AND International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma (free) AND Guidelines for Severe Uncontrolled Asthma – Spanish Society of Pulmonology and Thoracic Surgery (free) AND Nordic consensus statement on the systematic assessment and management of possible severe asthma in adults (free)
Guideline: Acute Exacerbation of Bronchiectasis (Non-cystic Fibrosis)
7 Feb, 2019 | 01:07h | UTCRelated: British Thoracic Society Guideline for bronchiectasis in adults – Thorax (free)
Position Statement: Comprehensive Management of Fibrotic Interstitial Lung Diseases
6 Feb, 2019 | 01:11h | UTCRelated: The interstitial lung disease multidisciplinary meeting: A position statement from the Thoracic Society of Australia and New Zealand and the Lung Foundation Australia (free) AND Interstitial Lung Disease and Pulmonary Fibrosis: A Practical Approach for General Medicine Physicians with Focus on the Medical History – Journal of Clinical Medicine (free) AND Pharmacological management of progressive-fibrosing interstitial lung diseases: a review of the current evidence – European Respiratory Review(free)
Meta-Analysis: Reviewing Inhaler Technique for Older People with COPD Can Improve Disease Control
6 Feb, 2019 | 00:46h | UTCReviewing inhaler technique for older people with COPD can improve disease control – NIHR Signal (free)
Original Study: Inhaler Technique Education and Exacerbation Risk in Older Adults with Asthma or Chronic Obstructive Pulmonary Disease: A Meta‐Analysis – Journal of the American Geriatrics Society (free)
Systematic Review: Phosphodiesterase 5 Inhibitors for Pulmonary Hypertension
4 Feb, 2019 | 21:48h | UTCPhosphodiesterase 5 inhibitors for pulmonary hypertension – Cochrane Library (free)
Summary: PDE5 inhibitors for pulmonary hypertension – Cochrane Library (free)
Review: Oral Appliances in the Management of Obstructive Sleep Apnea
4 Feb, 2019 | 22:00h | UTCOral Appliances in the Management of Obstructive Sleep Apnea – Sleep Medicine Clinics (free)
ATS Guideline: Home Oxygen Therapy for Children
3 Feb, 2019 | 15:48h | UTCNews Release: ATS Publishes New Clinical Guideline on Home Oxygen for Children (free)
Study: Association of Electronic Cigarette Use With Subsequent Initiation of Tobacco Cigarettes in Youths
3 Feb, 2019 | 12:14h | UTCCommentary: Teens who use e-cigarettes are FOUR TIMES more likely to take up tobacco smoking than teens who don’t, study says – The Daily Mail (free)
Related: Report: Public Health Consequences of E-Cigarettes (free report and commentaries) AND Simulation model: quantifying the health benefits and harms of e-cigarettes (free study and commentary) AND E-cigarettes: A win or loss for public health? – Knowable Magazine (free) AND FDA Takes New Steps to Address Epidemic of Youth E-Cigarette Use (free statement and commentaries)
Related Commentary on Twitter
E-cigs associated with risk for new cigarette use, even in low-risk youth. A fifth of new smoking in US youth may be attributable to prior e-cig use. https://t.co/2FEm0mmfEj #VisualAbstract #vaping pic.twitter.com/gtRwVH6BRp
— JAMA Network Open (@JAMANetworkOpen) February 2, 2019
Review: Benefits of Non‐invasive Ventilation in Acute Hypercapnic Respiratory Failure
3 Feb, 2019 | 11:30h | UTCBenefits of non‐invasive ventilation in acute hypercapnic respiratory failure – Respirology (free)
Related Guidelines: BTS/ICS guideline for the ventilatory management of acute hypercapnic respiratory failure in adults – Thorax (free) AND The Japanese Respiratory Society Noninvasive Positive Pressure Ventilation (NPPV) Guidelines – Respiratory Investigation (free) AND Management of COPD exacerbations: a European Respiratory Society/American Thoracic Society guideline – European Respiratory Journal (free)
Related Reviews: Non‐invasive ventilation for the management of acute hypercapnic respiratory failure due to exacerbation of chronic obstructive pulmonary disease – Cochrane Library (free) AND Noninvasive ventilation in acute respiratory failure: which recipe for success? – European Respiratory Review (free)
Review: Interstitial Lung Disease and Other Pulmonary Manifestations in Connective Tissue Diseases
1 Feb, 2019 | 02:40h | UTC
Randomized Trial: E-Cigarettes vs. Nicotine-Replacement Therapy
30 Jan, 2019 | 23:35h | UTCA Randomized Trial of E-Cigarettes versus Nicotine-Replacement Therapy – New England Journal of Medicine (link to abstract – $ for full-text)
Editorial: The Dangerous Flavors of E-Cigarettes (free)
Commentaries: E-cigarettes more effective than nicotine replacement therapies, finds major trial – Queen Mary University of London (free) AND UK study shows e-cigarettes help adult smokers quit, but US experts urge caution – CNN (free) AND E-Cigarettes Are Effective at Helping Smokers Quit, a Study Says – The New York times (10 articles per month are free) AND E-cigarettes ‘much better for quitting smoking’ – BBC (free) AND Study Found Vaping Beat Traditional Smoking-Cessation Options – NPR (free)
Related Commentary on Twitter
Trial finds e-cigarettes more effective than nicotine-replacement therapy with respect to the 1-year abstinence rate (18% vs. 10%). Throat or mouth irritation was more common with e-cigarettes, and nausea was more common with nicotine-replacement. https://t.co/cyEnDP630v pic.twitter.com/1je5vN87ru
— NEJM (@NEJM) January 30, 2019
Observational Study: β-Blocker Therapy Reduces the Risk for COPD Hospitalization
30 Jan, 2019 | 01:22h | UTCCommentary: Beta-Blocker Use Linked to Lower Risk for COPD Hospitalization – NEJM Journal Watch (free)
Related review and meta-analysis: Beta-blockers in patients with chronic obstructive disease and coexistent cardiac illnesses – COPD Research and Practice (free) AND Beta-blocker use and COPD mortality: a systematic review and meta-analysis – BMC Pulmonary Medicine (free)
Related observational studies: β-Blockers in COPD: A Cohort Study From the TONADO Research Program – CHEST (free) AND Effect of β blockers in treatment of chronic obstructive pulmonary disease: a retrospective cohort study – The BMJ (free)
Interstitial Lung Disease and Pulmonary Fibrosis: A Practical Approach for General Medicine Physicians with Focus on the Medical History
28 Jan, 2019 | 23:38h | UTC
CHEST Guideline: Therapy for Pulmonary Arterial Hypertension in Adults
24 Jan, 2019 | 00:23h | UTCRelated Guidelines: 2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension (free) AND Pediatric Pulmonary Hypertension: Guidelines From the American Heart Association and American Thoracic Society (free)
Study: Automated Triaging of Adult Chest Radiographs with Deep Artificial Neural Networks
23 Jan, 2019 | 01:15h | UTCAutomated Triaging of Adult Chest Radiographs with Deep Artificial Neural Networks – Radiology (free for a limited period)
Commentary: AI interprets chest x-rays, prioritizes critical findings – Radiology Business (free)
Related Commentary on Twitter
Deep learning #AI of over 470,000 Chest X-Rays to accurately triage and reduce the time to reporting from 11 to < 3 days for critical findings https://t.co/h7HSC8MrXv @radiology_rsna @MauroAnnarumma and colleagues @KingsCollegeLon pic.twitter.com/1v3Bk0yao3
— Eric Topol (@EricTopol) January 22, 2019
Pulmonary Hypertension in Congenital Heart Disease and Pregnancy: Summary of AHA/ACC ACHD and ESC Pregnancy Guidelines
23 Jan, 2019 | 00:50h | UTCOriginal Guidelines: 2018 ESC Guidelines for the management of cardiovascular diseases during pregnancy (free) AND 2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension (free) AND 2018 AHA/ACC Guideline for the Management of Adults With Congenital Heart Disease (free PDF)
Obstructive Sleep Apnea in Cardiovascular Disease: A Review of the Literature and Proposed Multidisciplinary Clinical Management Strategy
22 Jan, 2019 | 12:40h | UTCRelated Reviews: Sleep Apnea and Cardiovascular Disease: Lessons from Recent Trials and Need for Team Science – Circulation (free) AND Sleep Apnea: Types, Mechanisms, and Clinical Cardiovascular Consequences – Journal of the American College of Cardiology (free)
Weaning Failure of Cardiovascular Origin: How to Suspect, Detect and Treat
21 Jan, 2019 | 23:38h | UTC
Review: Interstitial Lung Disease Associated with Systemic Sclerosis
21 Jan, 2019 | 14:12h | UTCInterstitial lung disease associated with systemic sclerosis (SSc-ILD) – Respiratory Research (free)
Meta-Analysis: Vitamin D to Prevent Exacerbations of COPD
17 Jan, 2019 | 00:08h | UTCVitamin D to prevent exacerbations of COPD: systematic review and meta-analysis of individual participant data from randomised controlled trials – Thorax (link to abstract – $ for full-text)
Commentary: Treat vitamin D deficiency to prevent attacks of chronic obstructive pulmonary disease – The Conversation (free)