Chest Medicine
Short Review: Interpreting Pleural Fluid Results
29 May, 2019 | 10:40h | UTCInterpreting pleural fluid results – Clinical Medicine (free)
Source: Critical Care Reviews Newsletter
[Abstract Only] Cohort Study: Long‐term Risk of Recurrence in Patients with a First Unprovoked Venous Thromboembolism Managed According to D‐dimer Results
28 May, 2019 | 10:33h | UTCLong‐term risk of recurrence in patients with a first unprovoked venous thromboembolism managed according to d‐dimer results; A cohort study – Journal of Thrombosis and Haemostasis (link to abstract – $ for full-text)
Commentary: VTE Recurrence After Negative D-Dimer Testing – Journal Watch (free)
Guidelines on the Management of Acute Respiratory Distress Syndrome
28 May, 2019 | 01:26h | UTCGuidelines on the management of acute respiratory distress syndrome – BMJ Open Respiratory Research (free)
Related Reviews: Acute Respiratory Distress Syndrome – Nature Reviews Disease Primer (free PDF) AND Acute Respiratory Distress Syndrome – European Respiratory Review (free)
Related Guidelines: The clinical practice guideline for the management of ARDS in Japan – Journal of Intensive Care (free) AND An Official American Thoracic Society/European Society of Intensive Care Medicine/Society of Critical Care Medicine Clinical Practice Guideline: Mechanical Ventilation in Adult Patients with Acute Respiratory Distress Syndrome (free)
Source: Critical Care Reviews Newsletter
Systematic Review: Head‐to‐head Oral Prophylactic Antibiotics for COPD
28 May, 2019 | 01:14h | UTCHead‐to‐head oral prophylactic antibiotic therapy for chronic obstructive pulmonary disease – Cochrane Library (free)
Summary: Prophylactic antibiotic therapy for people with chronic obstructive lung disease (COPD) – Cochrane Library (free)
Related Cochrane Review: Prophylactic Antibiotic Therapy for COPD (free)
[Abstract Only] Meta-Analysis: Impact of the Pattern of Interstitial Lung Disease on Mortality in Rheumatoid Arthritis
25 May, 2019 | 18:33h | UTCImpact of the pattern of interstitial lung disease on mortality in rheumatoid arthritis: A systematic literature review and meta-analysis – Seminars in Arthritis and Rheumatism (link to abstract – $ for full-text)
Commentary: Lung Disease in RA: Which Factors are Linked With Mortality? – MedPage Today, via RheumNow (free)
NCCN Clinical Practice Guidelines in Oncology: 2019 Updates
25 May, 2019 | 18:30h | UTCNCCN Clinical Practice Guidelines in Oncology: 2019 Updates – The ASCO Post (free)
[Abstract Only] Randomized Trial: Patients with COPD Exacerbation and Low Eosinophil Count May be Treated with Shorter Corticosteroid Treatment
24 May, 2019 | 05:19h | UTCEosinophil-guided corticosteroid therapy in patients admitted to hospital with COPD exacerbation (CORTICO-COP): a multicentre, randomised, controlled, open-label, non-inferiority trial – The Lancet Respiratory Medicine (link to abstract – $ for full-text)
Commentary: 2 Minute Medicine Rewind May 20, 2019 (4th Summary)
See also: Video Summary – Medwire News (free audio)
Related Commentary on Twitter
Presenting now at #ATS2019 @atscommunity—Eosinophil-guided corticosteroid therapy in patients admitted to hospital with #COPD exacerbation (CORTICO-COP): a multicentre, randomised, controlled, open-label, non-inferiority trial https://t.co/YqUlX54gc5 pic.twitter.com/Bw1n9Tuink
— The Lancet Respiratory Medicine (@LancetRespirMed) May 20, 2019
Strategies to Relieve Dyspnea in Patients with Advanced Chronic Respiratory Diseases
24 May, 2019 | 05:16h | UTC
Systematic Review: Galactomannan Detection in Broncho‐alveolar Lavage Fluid for Invasive Aspergillosis in Immunocompromised Patients
22 May, 2019 | 06:11h | UTCGalactomannan detection in broncho‐alveolar lavage fluid for invasive aspergillosis in immunocompromised patients – Cochrane Library (free)
Summary: Measuring galactomannan in lung-washing fluid to diagnose invasive aspergillosis in patients with an impaired immune system – Cochrane Library (free)
Systematic Review: Mucolytic Agents for Chronic Bronchitis or Chronic Obstructive Pulmonary Disease
22 May, 2019 | 06:16h | UTCMucolytic agents versus placebo for chronic bronchitis or chronic obstructive pulmonary disease – Cochrane Library (free)
Summary: Mucolytic agents for chronic bronchitis or chronic obstructive pulmonary disease – Cochrane Library (free)
Editorial: What’s New in Oxygen therapy?
22 May, 2019 | 05:57h | UTCWhat’s new in oxygen therapy? – Intensive Care Medicine (free)
Related: Guideline: Oxygen Therapy for Acutely Ill Medical Patients (free) AND Review: Oxygen Treatment in Intensive Care and Emergency Medicine (free) AND Meta-Analysis: Liberal vs Conservative Oxygen Therapy in Acutely ill Adults (link to abstract and commentary)
Source: Critical Care Reviews Newsletter
#ATS2019 – Controlled Trial of Budesonide–Formoterol as Needed for Mild Asthma
21 May, 2019 | 06:16h | UTCControlled Trial of Budesonide–Formoterol as Needed for Mild Asthma – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Treatment Changes for Mild Asthma? – NEJM Journal Watch (free)
Just Presented at the 2019 Meeting of the American Thoracic Society.
#ATS2019 – Randomized Trial: Nintedanib for Systemic Sclerosis–Associated Interstitial Lung Disease
21 May, 2019 | 06:13h | UTCNintedanib for Systemic Sclerosis–Associated Interstitial Lung Disease – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Nintedanib slows lung function decline in SSc-associated interstitial lung disease – Medicine Matters (free)
Just Presented at the 2019 Meeting of the American Thoracic Society.
#ATS2019 – Randomized Trial: Early Neuromuscular Blockade Do Not Benefit Patients with Acute Respiratory Distress Syndrome
21 May, 2019 | 06:18h | UTCEarly Neuromuscular Blockade in the Acute Respiratory Distress Syndrome – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: Sedation and controlled paralysis do not improve survival of ICU patients with ARDS – University of Pittsburgh (free)
Just Presented at the 2019 Meeting of the American Thoracic Society.
Related Commentary on Twitter
This trial revisited research conducted about a decade ago that showed a survival benefit with early neuromuscular blockade in patients with acute respiratory distress syndrome (ARDS). See the results of the new trial: https://t.co/lcLOUirsOM #ATS2019
— NEJM (@NEJM) May 19, 2019
#ATS2019 – Randomized Trial: Patients with Mild Asma and Low Sputum Eosinophil Levels Do Not Benefit from Inhaled Corticosteroids
21 May, 2019 | 06:15h | UTCMometasone or Tiotropium in Mild Asthma with a Low Sputum Eosinophil Level – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Large portion of patients with mild persistent asthma and low sputum eosinophils respond equally well to inhaled corticosteroids as placebo – NIH News Releases (free)
Just Presented at the 2019 Meeting of the American Thoracic Society.
Google’s AI Improves Accuracy of Lung Cancer Diagnosis, Study Shows
21 May, 2019 | 06:10h | UTCGoogle’s AI improves accuracy of lung cancer diagnosis, study shows – STAT (free)
See also: A.I. Took a Test to Detect Lung Cancer. It Got an A. – The New York Times (10 articles per month are free)
Original Article: End-to-end lung cancer screening with three-dimensional deep learning on low-dose chest computed tomography – Nature Medicine (link to abstract – $ for full-text)
Evaluation of the Solitary Pulmonary Nodule
19 May, 2019 | 21:47h | UTCEvaluation of the Solitary Pulmonary Nodule – Internal Medicine Journal (free)
Related: Guidelines for Management of Incidental Pulmonary Nodules Detected on CT Images: From the Fleischner Society 2017 – Radiology (free) AND Diagnosis and Management of Lung Cancer, 3rd ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (free) AND British Thoracic Society guidelines for the investigation and management of pulmonary nodules (free) AND Management pathways for solitary pulmonary nodules – Journal of Thoracic Disease (free)
Unrecognized Severe Obstructive Sleep Apnea Associated with Increased Postoperative Cardiovascular Complications
15 May, 2019 | 06:53h | UTCAssociation of Unrecognized Obstructive Sleep Apnea With Postoperative Cardiovascular Events – JAMA (free for a limited period)
Editorial: Unrecognized Obstructive Sleep Apnea and Postoperative Cardiovascular Complications: A Wake-up Call – JAMA (free for a limited period)
Video Summary: Association of Undiagnosed Obstructive Sleep Apnea With Postoperative Cardiovascular Complications (free)
Commentary: Sleep apnea tied to heart problems after surgery – Reuters (free)
Related Guidelines: Society of Anesthesia and Sleep Medicine Guideline on Intraoperative Management of Adult Patients With Obstructive Sleep Apnea – Anesthesia & Analgesia (free) AND Practice Guidelines for the Perioperative Management of Patients with Obstructive Sleep Apnea: An Updated Report by the American Society of Anesthesiologists Task Force on Perioperative Management of Patients with Obstructive Sleep Apnea – Anesthesiology (free)
Study: Methotrexate Not Associated to Interstitial Lung Disease in RA
15 May, 2019 | 06:28h | UTCCommentary: Methotrexate Use Not Linked to Interstitial Lung Disease in RA – RheumNow (free)
Systematic Review: Impact of Non-drug Therapies on Asthma Control
13 May, 2019 | 01:05h | UTC
Randomized Trial: Acute Effects of Heat‐Not‐Burn, Electronic Vaping, and Traditional Tobacco Combustion Cigarettes
11 May, 2019 | 15:52h | UTC
Guideline: Diagnosis and Treatment of Pulmonary Arterial Hypertension
11 May, 2019 | 15:40h | UTC
Guideline: Lung Transplant Referral for Individuals with Cystic Fibrosis
11 May, 2019 | 15:38h | UTC
Indian Guidelines for Spirometry
9 May, 2019 | 18:23h | UTC
Randomized Trial: Azithromycin During Acute COPD Exacerbations Requiring Hospitalization
9 May, 2019 | 07:57h | UTCAzithromycin during Acute COPD Exacerbations Requiring Hospitalization (BACE): a Multicentre, Randomized, Double-blind, Placebo-controlled Trial – American Journal of Respiratory and Critical Care Medicine (link to abstract – $ for full-text)
Commentaries: Azithromycin appears to reduce treatment failure in severe, acute COPD exacerbations – American Thoracic Society (free) AND Azithromycin May Reduce Treatment Failure in Patients With Acute Exacerbation of COPD – AJMC (free)