Chest Medicine | Page 139 of 170 | Links Medicus Content Curation & Alerts in Medicine

Randomized Trial: Postextubation High-Flow Nasal Oxygen + Noninvasive Ventilation vs. High-Flow Nasal Oxygen Alone to Prevent Reintubation

3 Oct, 2019 | 08:04h | UTC

Effect of Postextubation High-Flow Nasal Oxygen With Noninvasive Ventilation vs High-Flow Nasal Oxygen Alone on Reintubation Among Patients at High Risk of Extubation Failure: A Randomized Clinical Trial – JAMA (free for a limited period)

Editorial: Added Benefit of Noninvasive Ventilation to High-Flow Nasal Oxygen to Prevent Reintubation in Higher-Risk Patients (free for a limited period)

In this RCT involving mechanically ventilated patients at high risk of extubation failure, high-flow nasal oxygen with NIV immediately after extubation decreased risk of reintubation compared with high-flow nasal oxygen alone https://t.co/YJD2yOU5Hw #LIVES2019

— JAMA (@JAMA_current) October 3, 2019

Study: Vaping-Associated Lung Injury Represents a Form of Airway-centered Chemical Pneumonitis

3 Oct, 2019 | 01:15h | UTC

Pathology of Vaping-Associated Lung Injury – New England Journal of Medicine (free)

Commentaries: Vaping-related lung injuries resemble chemical burns, study finds – STAT (free) AND U.S. doctors rule out pneumonia due to inhaled oil as cause of vaping injuries – Reuters (free) AND Lung Damage From Vaping Resembles Chemical Burns, Report Says – The New York Times (10 articles per month are free)

Related Commentary on Twitter

New letter describes 17 patients, all of whom vaped, who had lung biopsies after presenting with symptoms and bilateral pulmonary opacities that led to a clinical diagnosis of #vaping-associated lung injury. https://t.co/n5rF2OOOwq

— NEJM (@NEJM) October 2, 2019

ATS/IDSA Guideline: Diagnosis and Treatment of Adults with Community-acquired Pneumonia

2 Oct, 2019 | 02:14h | UTC

Diagnosis and Treatment of Adults with Community-acquired Pneumonia. An Official Clinical Practice Guideline of the American Thoracic Society and Infectious Diseases Society of America – American Journal of Respiratory and Critical Care Medicine (free)

News Release: ATS/IDSA publishes clinical guideline on community acquired pneumonia – American Thoracic Society (free)

Systematic Review: Can People Stop Smoking by Cutting Down the Amount they Smoke First?

2 Oct, 2019 | 01:51h | UTC

Smoking reduction interventions for smoking cessation – Cochrane Library (free)

Summary: Can people stop smoking by cutting down the amount they smoke first? – Cochrane Library (free)

Guidelines for Diagnostic Flexible Bronchoscopy in Adults

2 Oct, 2019 | 01:33h | UTC

Guidelines for Diagnostic Flexible Bronchoscopy in Adults: Joint Indian Chest Society/National College of Chest Physicians (I)/Indian Association for Bronchology Recommendations – Lung India (free)

[Abstract Only] Randomized Trial: Triple Therapy Inhaler for Uncontrolled Asthma

2 Oct, 2019 | 01:45h | UTC

Single inhaler extrafine triple therapy in uncontrolled asthma (TRIMARAN and TRIGGER): two double-blind, parallel-group, randomised, controlled phase 3 trials – The Lancet (link to abstract – $ for full-text)

Commentaries: Asthma 3-in-1 Therapy May Improve Lung Function, Study Shows – The New York Times (10 articles per month are free) AND Triple-Therapy Inhaler Tied to Better Lung Function in Asthma – NEJM Journal Watch (free)

Study Review: C-reactive Protein Testing in General Practice Safely Reduces Antibiotic use for COPD Flare-ups

2 Oct, 2019 | 01:43h | UTC

C-reactive protein testing in general practice safely reduces antibiotic use for COPD flare-ups – NIHR Signal (free)

Original Study: Randomized Trial: C-Reactive Protein Can Guide Antibiotics for COPD Exacerbations (link to abstract and commentaries)

High-altitude Illness: Management Approach

24 Sep, 2019 | 07:43h | UTC

High-altitude illness: Management approach – Turkish Journal of Emergency Medicine (free)

State of the Art Review: What are the Respiratory Effects of e-Cigarettes?

1 Oct, 2019 | 00:58h | UTC

What are the respiratory effects of e-cigarettes? – The BMJ (free for a limited period)

Related Commentary on Twitter

What are the respiratory effects of e-cigarettes? This review summarises the rapidly expanding evidence from cell culture, animal, and human studies on the potential pulmonary health effects of e-cigarettes https://t.co/MbEU8wlh6p @sejordt @bmj_company pic.twitter.com/7PKF4dldLM

— The BMJ (@bmj_latest) September 30, 2019

FDA Issues Drug Safety Alert on Severe Lung Inflammation Due to Treatment with CDK4/6 Inhibitors for Breast Cancer

1 Oct, 2019 | 00:36h | UTC

FDA warns about rare but severe lung inflammation with Ibrance, Kisqali, and Verzenio for breast cancer – U.S. Food & Drug Administration (free)

Commentary: FDA Issues Drug Safety Communication on Lung Inflammation Due to Treatment With CDK4/6 Inhibitors – The ASCO Post (free)

CDC Report: 76.9% of Patients with Vaping-related Lung Illnesses Used a THC-Containing Product

30 Sep, 2019 | 00:56h | UTC

Characteristics of a Multistate Outbreak of Lung Injury Associated with E-cigarette Use, or Vaping — United States, 2019 – Centers for Diseases Control and Prevention (free)

Commentaries: Many patients with vaping-related illnesses used THC, CDC reports – STAT (free) AND THC vape products may be the main culprit in the mysterious lung illness outbreak – Vox (free) AND U.S. CDC recommends against using vapes with marijuana ingredient – Reuters (free)

#ESMO19 – [Abstract Only] Randomized Trial: Improved Overall Survival with Combined Immunotherapy for Advanced Non–Small-Cell Lung Cancer

30 Sep, 2019 | 00:35h | UTC

Nivolumab plus Ipilimumab in Advanced Non–Small-Cell Lung Cancer – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: Two immunotherapy drug combination offers chemotherapy-free option for advanced NSCLC – European Society for Medical Oncology (free) AND Nivolumab/Low-dose Ipilimumab: A Potential Chemotherapy-Sparing Option in Advanced NSCLC – Pharmacy Times (free)

#ESMO19 – Just presented at the European Society of Medical Oncology Congress 2019 in Barcelona

Related Commentary on Twitter

Chemo-naïve patients with adv #NSCLC with PD-L1 expression assigned to nivolumab + ipilimumab, nivolumab alone, or chemo. Patients receiving nivolumab + ipilimumab had better clin outcomes. See the CheckMate 227 trial. #ESMO19 https://t.co/jU9S62qZLa

— NEJM (@NEJM) September 28, 2019

Randomized Trial: Protocolized Non-invasive vs. Invasive Weaning from Mechanical Ventilation for Adults in Intensive Care

30 Sep, 2019 | 00:16h | UTC

Protocolised non-invasive compared with invasive weaning from mechanical ventilation for adults in intensive care – Health Technology Assessment (free)

Source: Critical Care Reviews Newsletter

“A protocolized non-invasive weaning strategy did not reduce time to liberation from ventilation. However, patients who underwent non-invasive weaning had fewer days requiring IMV and required fewer antibiotics for respiratory infections.”