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Chest Medicine

Meta-Analysis: Interventions for the Management of Malignant Pleural Effusions

23 Apr, 2020 | 09:22h | UTC

Interventions for the management of malignant pleural effusions: a network meta‐analysis – Cochrane Library

 


NIH COVID-19 Treatment Guidelines

22 Apr, 2020 | 09:02h | UTC

NIH Coronavirus Disease 2019 (COVID-19) Treatment Guidelines – National Institutes of Health

News Release: Expert U.S. panel develops NIH treatment guidelines for COVID-19

Commentary: New U.S. Treatment Guidelines for Covid-19 Don’t See Much Progress – The New York Times

 


[Preprint] Observational Study: No Benefit from Hydroxychloroquine in Patients Hospitalized with Covid-19

22 Apr, 2020 | 08:58h | UTC

Outcomes of hydroxychloroquine usage in United States veterans hospitalized with Covid-19 – medRxiv

Commentaries: Study finds no benefit, higher death rate in patients taking hydroxychloroquine for Covid-19 – CNN AND More deaths, no benefit from malaria drug in VA virus study – Associated Press

 


Evidence Review: Tests for Screening, Diagnosis and Monitoring of COVID-19

22 Apr, 2020 | 08:55h | UTC

What tests could potentially be used for the screening, diagnosis and monitoring of COVID-19 and what are their advantages and disadvantages? – CEBM University of Oxford

 


Study: SARS-CoV-2 Persists Longer in Stool and in Patients with Severe Disease

22 Apr, 2020 | 08:53h | UTC

Viral load dynamics and disease severity in patients infected with SARS-CoV-2 in Zhejiang province, China, January-March 2020: retrospective cohort study – The BMJ

 


Richard Lehman’s Covid-19 Reviews—20 April 2020

22 Apr, 2020 | 08:50h | UTC

Richard Lehman’s covid-19 reviews, 20 April 2020 – The BMJ Opinion

“In this weekly round-up, Richard Lehman looks at a personal selection of articles of relevance to clinicians dealing with covid-19”.

 


Video: Perspectives on the Pandemic | Dr. John Ioannidis Update

21 Apr, 2020 | 08:12h | UTC

Perspectives on the Pandemic | Dr. John Ioannidis Update: 4.17.20

Related (from Dr. John Ioannidis): Antibody Tests Suggest that Coronavirus Infections Vastly Exceed Official Counts AND Study: Population-level COVID-19 Mortality Risk

 


Therapeutic Strategies for Critically Ill Patients with COVID-19

21 Apr, 2020 | 08:14h | UTC

Therapeutic strategies for critically ill patients with COVID-19 – Annals of Intensive Care

 


Opinion – Timed & Titrated use of Steroids in COVID-19?

21 Apr, 2020 | 08:11h | UTC

Timed & titrated use of steroid in COVID-19? – PulmCrit

 


FDA Letter Warns About the Limitations of Antibody Tests for COVID-19

21 Apr, 2020 | 08:08h | UTC

Important Information on the Use of Serological (Antibody) Tests for COVID-19 – Letter to Health Care Providers – U.S. Food & Drug Administration

See also: Coronavirus (COVID-19) Update: Serological Test Validation and Education Efforts – U.S. Food & Drug Administration

Commentary: FDA Warns Providers About Limits of SARS-CoV-2 Antibody Tests – NEJM Journal Watch

 


D‐dimer Levels on Admission to Predict In‐hospital Mortality in Patients with Covid‐19

21 Apr, 2020 | 08:06h | UTC

D‐dimer levels on admission to predict in‐hospital mortality in patients with Covid‐19 – Journal of Thrombosis and Haemostasis

Related: D-dimer is Associated with Severity of Coronavirus Disease 2019: A Pooled Analysis – Thrombosis and Haemostasis

 


Thrombocytopenia and Its Association with Mortality in Patients with COVID‐19

21 Apr, 2020 | 08:04h | UTC

Thrombocytopenia and Its Association with Mortality in Patients with COVID‐19 – Journal of Thrombosis and Haemostasis

Related: Thrombocytopenia is associated with severe coronavirus disease 2019 (COVID-19) infections: A meta-analysis – Clinica Chimica Acta

 


[Preprint] Meta-Analysis: Smoking is Associated with COVID-19 Progression

21 Apr, 2020 | 08:02h | UTC

Smoking is Associated with COVID-19 Progression: A Meta-Analysis – medRxiv

Commentary: Smoking doubles risk of severe COVID-19 disease – News Medical

 


ATS Guideline: Diagnosis and Detection of Sarcoidosis

21 Apr, 2020 | 08:00h | UTC

Diagnosis and Detection of Sarcoidosis. An Official American Thoracic Society Clinical Practice Guideline – American Journal of Respiratory and Critical Care Medicine

News Release: First official ATS practice guidelines for Sarcoidosis cover diagnosis and detection – American Thoracic Society

 


Antibody Tests Suggest that Coronavirus Infections Vastly Exceed Official Counts

20 Apr, 2020 | 00:25h | UTC

Antibody tests suggest that coronavirus infections vastly exceed official counts – Nature

See original preprint study: COVID-19 Antibody Seroprevalence in Santa Clara County, California – medRxiv

Author interview: Dr. John Ioannidis Announces Results of COVID-19 Serology Study (video)

Other commentaries: Far more people may have been infected by coronavirus in one California county, study estimates – CNN AND The number of coronavirus infections in Santa Clara, California may be up to 85 times higher than testing shows, according to new research – Business Insider AND Up to 4% of Silicon Valley is already infected with coronavirus – MIT Technology Review

 


The Promise and Peril of Antibody Testing for COVID-19

20 Apr, 2020 | 00:23h | UTC

The Promise and Peril of Antibody Testing for COVID-19 – JAMA

See also: Will antibody tests for the coronavirus really change everything? – Nature AND Antibody Test, Seen as Key to Reopening Country, Does Not Yet Deliver – The New York Times AND With Broad, Random Tests for Antibodies, Germany Seeks Path out of Lockdown

 


How Does Coronavirus Kill?

20 Apr, 2020 | 00:21h | UTC

How does coronavirus kill? Clinicians trace a ferocious rampage through the body, from brain to toes – Science

 


Review: COVID-19 and Thrombotic or Thromboembolic Disease

20 Apr, 2020 | 00:18h | UTC

COVID-19 and Thrombotic or Thromboembolic Disease: Implications for Prevention, Antithrombotic Therapy, and Follow-up – Journal of the American College of Cardiology

Commentary: JACC Paper Outlines Implications, Considerations For Thrombotic Disease Patients During COVID-19 Pandemic – American College of Cardiology

 


The Science Underlying COVID-19: Implications for the Cardiovascular System

20 Apr, 2020 | 00:19h | UTC

The Science Underlying COVID-19: Implications for the Cardiovascular System – Circulation

 


Editorial: COVID-19 Pneumonia: ARDS or Not? – Critical Care

20 Apr, 2020 | 00:09h | UTC

Editorial: COVID-19 pneumonia: ARDS or not? – Critical Care

Related: COVID-19 pneumonia: different respiratory treatment for different phenotypes? – Intensive Care Medicine AND Covid-19 Does Not Lead to a “Typical” Acute Respiratory Distress Syndrome – American Journal of Respiratory and Critical Care Medicine

 


What’s Happening with Remdesivir?

20 Apr, 2020 | 00:12h | UTC

What’s Happening With Remdesivir? – Science Translational Medicine

See also: Slow down your giddyup on Gilead news – Health News Review

 


Defining ARDS & Recruitability, with Implications for COVID Treatment

20 Apr, 2020 | 00:06h | UTC

Defining ARDS & recruitability, with implications for COVID treatment – PulmCrit

 


Hospital Preparedness for COVID-19: A Practical Guide from a Critical Care Perspective

20 Apr, 2020 | 00:07h | UTC

Hospital Preparedness for COVID-19: A Practical Guide from a Critical Care Perspective – American Journal of Respiratory and Critical Care Medicine

 


Observational Study: Inpatient Use of Angiotensin Converting Enzyme Inhibitors and Angiotensin II Receptor Blockers Seems Safe Among Patients with Hypertension Hospitalized With COVID-19

20 Apr, 2020 | 00:01h | UTC

Association of Inpatient Use of Angiotensin Converting Enzyme Inhibitors and Angiotensin II Receptor Blockers with Mortality Among Patients With Hypertension Hospitalized With COVID-19 – Circulation Research

 


Systematic Review: Prophylactic Role of Chloroquine and Hydroxychloroquine in COVID‐19

19 Apr, 2020 | 23:57h | UTC

A systematic review of the prophylactic role of chloroquine and hydroxychloroquine in Coronavirus Disease‐19 (COVID‐19) – International Journal of Rheumatic Diseases

Commentary: ‘Dearth of evidence’ to support prophylactic chloroquine, hydroxychloroquine use for COVID-19 – Medicine Matters

 


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