Chest Medicine
Systematic Review: Rapid, point‐of‐care antigen and molecular‐based tests for diagnosis of SARS‐CoV‐2 infection
27 Aug, 2020 | 09:55h | UTC
Commentary on Twitter (Thread – Click for more)
We have published our next Cochrane review of Covid-19 tests:
Rapid, point‐of‐care antigen and molecular‐based tests for diagnosis of SARS‐CoV‐2 infection – Dinnes, J – 2020 | Cochrane Library https://t.co/EhD0onSgH0
— Jon Deeks FMedSci (@deeksj) August 26, 2020
Too many COVID-19 patients get unneeded ‘just in case’ antibiotics
27 Aug, 2020 | 10:00h | UTCToo many COVID-19 patients get unneeded ‘just in case’ antibiotics – University of Michigan
[Abstract Only] Observational study: Therapeutic and prophylactic anticoagulation linked to lower in-hospital mortality in patients with Covid-19
27 Aug, 2020 | 09:51h | UTCCommentaries: Study provides more data on blood thinner efficacy for COVID-19 – The Mount Sinai Hospital AND Anticoagulants Associated With Better Survival, Lower Risk of Intubation in COVID-19 Patients
COVID-19 re-infection by a phylogenetically distinct SARS-coronavirus-2 strain confirmed by whole genome sequencing
26 Aug, 2020 | 04:13h | UTCSee also: First Covid-19 reinfection documented in Hong Kong
Duration of SARS-CoV-2 infectivity: When is it safe to discontinue isolation?
26 Aug, 2020 | 04:14h | UTC
BCG vaccination in infancy does not protect against COVID-19. Evidence from a natural experiment in Sweden
26 Aug, 2020 | 04:12h | UTC
Post-discharge persistent symptoms and health-related quality of life after hospitalization for COVID-19
26 Aug, 2020 | 04:09h | UTCCommentary: COVID-19 symptoms can persist for months after hospital stay – CIDRAP
Two meters or one: What is the evidence for physical distancing in Covid-19?
26 Aug, 2020 | 04:08h | UTCTwo metres or one: what is the evidence for physical distancing in covid-19? – The BMJ
Commentary: Rigid social distancing rules for COVID-19 based on outdated science – British Medical Journal
Systematic review: Effect of renin-angiotensin-aldosterone system inhibitors in patients with COVID-19
26 Aug, 2020 | 04:05h | UTCCommentaries: Expert reaction to study looking at blood pressure medicines and COVID-19 – Science Media Centre AND Coronavirus Treatment: Blood Pressure Medicines May Reduce COVID-19 Severity, Deaths: Study – International Business Times
Nosocomial COVID-19 infection: Examining the risk of mortality
26 Aug, 2020 | 04:04h | UTCCommentary: Expert reaction to a study looking at hospital-acquired COVID-19 infections – Science Media Centre
New drool-based tests are replacing the dreaded coronavirus nasal swab
26 Aug, 2020 | 03:59h | UTCNew drool-based tests are replacing the dreaded coronavirus nasal swab – Science
Observational study: Risk of hydroxychloroquine alone and in combination with azithromycin in the treatment of rheumatoid arthritis
26 Aug, 2020 | 03:57h | UTC
Randomized trial: Vitamin D Supplementation does not prevent severe asthma exacerbations in children with asthma and low vitamin D levels
26 Aug, 2020 | 03:52h | UTCEffect of Vitamin D3 Supplementation on Severe Asthma Exacerbations in Children With Asthma and Low Vitamin D Levels: The VDKA Randomized Clinical Trial – JAMA (free for a limited period)
Commentary: Compared to placebo, vitamin D has no benefit for severe asthma attacks, study finds – University of Pittsburgh School of Medicine AND Don’t count on vitamin D to ease childhood asthma – MedicalXpress
Commentary on Twitter
In this RCT, #vitaminD3 supplementation did not improve the time to a severe asthma exacerbation vs placebo in children with persistent asthma and low #vitaminD levels https://t.co/VfYXUrhyT7
— JAMA (@JAMA_current) August 25, 2020
First Covid-19 reinfection documented in Hong Kong
25 Aug, 2020 | 04:00h | UTCFirst Covid-19 reinfection documented in Hong Kong, researchers say – STAT
Commentaries: Some people can get the pandemic virus twice, a study suggests. That is no reason to panic – Science AND You can get reinfected with Covid-19 but still have immunity. Let’s explain – Vox AND Expert reaction to first reported case of COVID-19 re-infection in Hong Kong patient – Science Media Centre
Commentary on Twitter
In Hong Kong, researchers reported what appears to be the first confirmed case of Covid-19 reinfection in a 33-year-old man. The virus sequenced from his two infections didn't match, indicating the second one was not tied to the first. https://t.co/4GHd1lMRZ0
— STAT (@statnews) August 24, 2020
FDA issues emergency use authorization for convalescent plasma as potential COVID–19 treatment
25 Aug, 2020 | 03:58h | UTCCommentaries: Convalescent Plasma: The Science and the Politics – Science Translational Medicine AND Convalescent plasma: another controversial clash of politics & science – Health News Review AND Observational Study of Convalescent Plasma and FDA Response – datamethods AND FDA OKs use of convalescent plasma for COVID-1 – CIDRAP AND Is convalescent plasma safe and effective? We answer the major questions about the Covid-19 treatment – STAT
Anticipating and managing coagulopathy and thrombotic manifestations of severe COVID-19
25 Aug, 2020 | 03:53h | UTC
An inflammatory cytokine signature predicts COVID-19 severity and survival
25 Aug, 2020 | 03:57h | UTCAn inflammatory cytokine signature predicts COVID-19 severity and survival – Nature
Commentary: Researchers discover immune predictors of COVID-19 cases that fare the worst – The Mount Sinai Hospital
Commentary on Twitter
Elevated levels of serum IL-6 and TNF-α at the time of hospitalization are independent and significant predictors of clinical outcome in two cohorts of patients with #COVID19 #biomarker @IcahnMountSinai @SinaiImmunol @TischCancer @MiriamMerad https://t.co/syHWT6QaW0
— Nature Medicine (@NatureMedicine) August 24, 2020
Not just antibodies: B cells and T cells mediate immunity to COVID-19
25 Aug, 2020 | 03:54h | UTCNot just antibodies: B cells and T cells mediate immunity to COVID-19 – Nature Reviews Immunology
Commentary on Twitter
Concise and useful summary of the B and T cell response to #COVID19https://t.co/RQ2ABn8CYf@NatRevImmunol pic.twitter.com/Bk9IiJFfwQ
— Eric Topol (@EricTopol) August 24, 2020
Diagnostic and prognostic value of hematological and immunological markers in COVID-19 infection: A meta-analysis of 6320 patients
25 Aug, 2020 | 03:45h | UTC
Randomized trial: Remdesivir vs. standard care in patients with moderate COVID-19
24 Aug, 2020 | 00:53h | UTCEditorial: Efficacy of Remdesivir in COVID-19
Commentaries: Study: Remdesivir doesn’t boost outcomes in moderate pneumonia from COVID-19 – UPI AND New Remdesivir Study Shows the Trouble With Bad Science – The Wire
Commentary on Twitter
Remdesivir….good editorial, concludes we don't know who to give it to, nor for how long, nor if it improves outcomes, nor whether, if it does, it does that beyond what dexamethasone or other corticosteroids do. https://t.co/Qi1dTSPcYi
— Dr. Tom Frieden (@DrTomFrieden) August 21, 2020
COVID-19: Interim guidance on rehabilitation in the hospital and post-hospital phase
24 Aug, 2020 | 00:54h | UTC
Review: The interpretation of SARS-CoV-2 diagnostic tests
24 Aug, 2020 | 00:40h | UTCThe Interpretation of SARS-CoV-2 Diagnostic Tests – Med
Recurrence or relapse of COVID‐19 in older patients: A description of three cases
24 Aug, 2020 | 00:42h | UTC
Perspective by Dr. Tom Frieden: Coronavirus immunity offers perils and promise
24 Aug, 2020 | 00:37h | UTCCoronavirus immunity offers perils and promise – CNN
CDC Guideline: Prevention and control of seasonal influenza with vaccines
24 Aug, 2020 | 00:29h | UTC