Chest Medicine (all articles)
Anticoagulation in COVID-19: A systematic review, meta-analysis and rapid guidance from the Mayo Clinic
1 Sep, 2020 | 06:26h | UTC
Cases of SARS-CoV-2 reinfection highlight the limitations — and the mysteries — of our immune system
1 Sep, 2020 | 06:18h | UTC
Asthma in COVID-19 hospitalizations: An overestimated risk factor?
1 Sep, 2020 | 06:22h | UTC
Commentary on Twitter
Happy to share our research letter showing that asthma is not a significant comorbidity for patients hospitalized with severe covid, and that it does not increase risk for mechanical ventilation. https://t.co/ylHjAis3Xl pic.twitter.com/Oy10kYKT6W
— fernando holguin (@holguinf01) August 31, 2020
Scientists are reporting several cases of Covid-19 reinfection — but the implications are complicated
1 Sep, 2020 | 06:20h | UTC
What Is the predictive value of a single nasopharyngeal SARS-CoV-2 PCR swab test in a patient with COVID-like symptoms and / or significant COVID-19 exposure?
1 Sep, 2020 | 06:12h | UTC
Commentary on Twitter
What Is the Predictive Value of a Single Nasopharyngeal SARS-CoV-2 PCR Swab Test in a Patient with COVID-like Symptoms and / or Significant #COVID19 Exposure?
The PCR-test was found to be 87% sensitive, 97% specific, a PPV of 0.98, and a NPV of 0.80 #ofid https://t.co/MGQdzDsd8k— Antibiotic Steward? Bassam Ghanem (@ABsteward) August 31, 2020
Choosing Wisely: Five low-value or harmful practices that should be avoided in pediatric pulmonology and sleep medicine
1 Sep, 2020 | 05:57h | UTCCommentary: Choosing Wisely: 5 Practices to Avoid in Pediatric Pulmonology and Sleep Medicine – NEJM Journal Watch
See complete lists of low-value practices: Choosing Wisely U.S. / Choosing Wisely UK / Choosing Wisely Australia AND Choosing Wisely Canada
Perspective: COVID-19 vaccine trials should seek worthwhile efficacy
31 Aug, 2020 | 01:45h | UTCCOVID-19 vaccine trials should seek worthwhile efficacy – The Lancet
Commentary: Covid vaccine rush could make pandemic worse, say scientists – The Guardian
Commentary on Twitter
"Although efficacy far greater than 50% would be better, efficacy of about 50% would represent substantial progress"
Philip Krause et al for the @WHO Solidarity Vaccines Trial Expert Group on why #COVID19 vaccine trials should seek worthwhile efficacy https://t.co/2VWas8YU7L pic.twitter.com/RjbeZkeAE0
— The Lancet (@TheLancet) August 28, 2020
Study: Saliva or nasopharyngeal swab specimens for detection of SARS-CoV-2
31 Aug, 2020 | 01:47h | UTCRelated study: Salivary Detection of COVID-19 – Annals of Internal Medicine
Commentary on Twitter
Just published @NEJM
Strong support for saliva as an alternative to nasopharyngeal swab samples to detect #SARSCoV2
by @awyllie13 @YaleSPH and team @YaleMed https://t.co/waF5ODmiV8 pic.twitter.com/zw1D2JqW0y— Eric Topol (@EricTopol) August 28, 2020
A national strategy to diagnose COVID-19 associated invasive fungal disease in the ICU
31 Aug, 2020 | 01:44h | UTC
Updated Covid-19 Reviews: Hydroxychloroquine or Chloroquine / Masks / ACE Inhibitors or ARBs
28 Aug, 2020 | 08:54h | UTC- Update Alert 2: Hydroxychloroquine or Chloroquine for the Treatment or Prophylaxis of COVID-19
- Update Alert 2: Masks for Prevention of Respiratory Virus Infections, Including SARS-CoV-2, in Health Care and Community Settings
- Update Alert 3: Risks and Impact of Angiotensin-Converting Enzyme Inhibitors or Angiotensin-Receptor Blockers on SARS-CoV-2 Infection in Adults
Pathophysiology of COVID-19-associated acute respiratory distress syndrome: A multicenter prospective observational study
28 Aug, 2020 | 08:50h | UTC
Individuals with obesity and COVID‐19: A global perspective on the epidemiology and biological relationships
27 Aug, 2020 | 09:57h | UTCCommentaries: Obesity increases risk of complications from Covid-19, damages vaccine efficacy, study finds – CNN AND Obesity increases risk of Covid-19 death by 48%, study finds – The Guardian AND Obesity linked with higher risk for COVID-19 complications – University of North Carolina at Chapel Hill
Systematic Review: Rapid, point‐of‐care antigen and molecular‐based tests for diagnosis of SARS‐CoV‐2 infection
27 Aug, 2020 | 09:55h | UTC
Commentary on Twitter (Thread – Click for more)
We have published our next Cochrane review of Covid-19 tests:
Rapid, point‐of‐care antigen and molecular‐based tests for diagnosis of SARS‐CoV‐2 infection – Dinnes, J – 2020 | Cochrane Library https://t.co/EhD0onSgH0
— Jon Deeks (@deeksj) August 26, 2020
Too many COVID-19 patients get unneeded ‘just in case’ antibiotics
27 Aug, 2020 | 10:00h | UTCToo many COVID-19 patients get unneeded ‘just in case’ antibiotics – University of Michigan
[Abstract Only] Observational study: Therapeutic and prophylactic anticoagulation linked to lower in-hospital mortality in patients with Covid-19
27 Aug, 2020 | 09:51h | UTCCommentaries: Study provides more data on blood thinner efficacy for COVID-19 – The Mount Sinai Hospital AND Anticoagulants Associated With Better Survival, Lower Risk of Intubation in COVID-19 Patients
COVID-19 re-infection by a phylogenetically distinct SARS-coronavirus-2 strain confirmed by whole genome sequencing
26 Aug, 2020 | 04:13h | UTCSee also: First Covid-19 reinfection documented in Hong Kong
Duration of SARS-CoV-2 infectivity: When is it safe to discontinue isolation?
26 Aug, 2020 | 04:14h | UTC
BCG vaccination in infancy does not protect against COVID-19. Evidence from a natural experiment in Sweden
26 Aug, 2020 | 04:12h | UTC
Post-discharge persistent symptoms and health-related quality of life after hospitalization for COVID-19
26 Aug, 2020 | 04:09h | UTCCommentary: COVID-19 symptoms can persist for months after hospital stay – CIDRAP
Two meters or one: What is the evidence for physical distancing in Covid-19?
26 Aug, 2020 | 04:08h | UTCTwo metres or one: what is the evidence for physical distancing in covid-19? – The BMJ
Commentary: Rigid social distancing rules for COVID-19 based on outdated science – British Medical Journal
Systematic review: Effect of renin-angiotensin-aldosterone system inhibitors in patients with COVID-19
26 Aug, 2020 | 04:05h | UTCCommentaries: Expert reaction to study looking at blood pressure medicines and COVID-19 – Science Media Centre AND Coronavirus Treatment: Blood Pressure Medicines May Reduce COVID-19 Severity, Deaths: Study – International Business Times
Nosocomial COVID-19 infection: Examining the risk of mortality
26 Aug, 2020 | 04:04h | UTCCommentary: Expert reaction to a study looking at hospital-acquired COVID-19 infections – Science Media Centre
New drool-based tests are replacing the dreaded coronavirus nasal swab
26 Aug, 2020 | 03:59h | UTCNew drool-based tests are replacing the dreaded coronavirus nasal swab – Science
Observational study: Risk of hydroxychloroquine alone and in combination with azithromycin in the treatment of rheumatoid arthritis
26 Aug, 2020 | 03:57h | UTC
Randomized trial: Vitamin D Supplementation does not prevent severe asthma exacerbations in children with asthma and low vitamin D levels
26 Aug, 2020 | 03:52h | UTCEffect of Vitamin D3 Supplementation on Severe Asthma Exacerbations in Children With Asthma and Low Vitamin D Levels: The VDKA Randomized Clinical Trial – JAMA (free for a limited period)
Commentary: Compared to placebo, vitamin D has no benefit for severe asthma attacks, study finds – University of Pittsburgh School of Medicine AND Don’t count on vitamin D to ease childhood asthma – MedicalXpress
Commentary on Twitter
In this RCT, #vitaminD3 supplementation did not improve the time to a severe asthma exacerbation vs placebo in children with persistent asthma and low #vitaminD levels https://t.co/VfYXUrhyT7
— JAMA (@JAMA_current) August 25, 2020