Cardiac Surgery
Clinical Update – Preventing Surgical Site Infections: Looking Beyond the Current Guidelines
23 Feb, 2020 | 22:21h | UTCPreventing Surgical Site Infections: Looking Beyond the Current Guidelines – JAMA (free for a limited period)
Related Guidelines: Centers for Disease Control and Prevention Guideline for the Prevention of Surgical Site Infection, 2017 – JAMA Surgery (free) AND Global guidelines on the prevention of surgical site infection – World Health Organization (free) AND Surgical site infections: prevention and treatment – National Institute for Health and Care Excellence (free) AND APSIC guidelines for the prevention of surgical site infections – Antimicrobial Resistance & Infection Control (free) AND Intraoperative surgical site infection control and prevention: a position paper and future addendum to WSES intra-abdominal infections guidelines – World Journal of Emergency Surgery (free)
Global, Regional, and National Burden of Congenital Heart Disease
23 Jan, 2020 | 09:36h | UTCInvited Commentary: Congenital heart disease: a global public health concern (free)
Related: Findings from the Global Burden of Disease Study 2017 – The Lancet / Institute for Health Metrics and Evaluation (free PDF)
Related Commentary on Twitter
Our latest study, "Global, regional, and national burden of congenital heart disease, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017," was published yesterday in @LancetChildAdol. Read the full study online: https://t.co/XEbz4aQFzr pic.twitter.com/SO6j7LX4V4
— Institute for Health Metrics and Evaluation (IHME) (@IHME_UW) January 22, 2020
Summary: Current AATS Guidelines on Surgical Treatment of Infective Endocarditis
23 Jan, 2020 | 01:54h | UTCOriginal Guideline: 2016 The American Association for Thoracic Surgery (AATS) consensus guidelines: Surgical treatment of infective endocarditis: Executive summary (free)
Related Guidelines: Infective Endocarditis in Adults: Diagnosis, Antimicrobial Therapy, and Management of Complications: A Scientific Statement for Healthcare Professionals From the American Heart Association (free) AND 2015 ESC Guidelines for the management of infective endocarditis (free)
Review: New‐onset Postoperative Atrial Fibrillation After Heart Surgery
21 Jan, 2020 | 01:04h | UTCRelated: Society of Cardiovascular Anesthesiologists/European Association of Cardiothoracic Anaesthetists Practice Advisory for the Management of Perioperative Atrial Fibrillation in Patients Undergoing Cardiac Surgery – Anesthesia & Analgesia (free) AND New-Onset Atrial Fibrillation in Adult Patients After Cardiac Surgery – Current Anesthesiology Reports (free)
ACC/AHA Appropriate Use Criteria for Multimodality Imaging During the Follow-Up Care of Patients With Congenital Heart Disease
12 Jan, 2020 | 21:29h | UTCCommentaries: Appropriate Use Criteria for Imaging of Congenital Heart Disease Patients: Key Points – American College of Cardiology (free) AND New AUC for Cardiac Imaging Follow-up in Congenital Heart Disease – TCTMD (free)
[Abstract Only] Study: Hepatitis C–positive Donors are a Viable Option for Heart Transplant
9 Jan, 2020 | 01:18h | UTCExpanding Heart Transplant in the Era of Direct-Acting Antiviral Therapy for Hepatitis C – JAMA Cardiology (link to abstract – $ for full-text)
Commentaries: Hepatitis C-positive donors a viable option to expand heart donor pool – Vanderbilt University Medical Center (free) AND Expanding heart transplant in the era of direct-acting antiviral therapy for hepatitis C – 2 Minute Medicine (free)
Related Studies: Transplant of Hepatitis C–Infected Kidneys Into Uninfected Recipients (link to abstract and commentaries) AND Heart and Lung Transplants from HCV-Infected Donors to Uninfected Recipients (link to abstract and commentaries) AND Direct-Acting Antiviral Prophylaxis in Kidney Transplantation From Hepatitis C Virus–Infected Donors to Noninfected Recipients (link to abstract and commentaries) AND Favorable 1-Year Outcomes with Transplantation of HCV-Viremic Kidneys (link to abstract and commentaries)
[Abstract Only] Randomized Trial: Angioplasty NOT Non-inferior to CABG for the Treatment of Unprotected Left Main Stenosis
5 Jan, 2020 | 14:19h | UTCPercutaneous coronary angioplasty versus coronary artery bypass grafting in the treatment of unprotected left main stenosis: updated 5-year outcomes from the randomised, non-inferiority NOBLE trial – The Lancet (link to abstract – $ for full-text)
Commentary: NOBLE at 5 Years: New Data Favor CABG for Left Main Disease – TCTMD (free)
Related: BBC Investigation on the Reporting of the EXCEL Trial Raises Concerns Over the Safety of Stents for Left Main Disease in Patients at Low Risk for Surgery (free investigation, video, and commentaries) AND EACTS Calls for Independent Left Main CAD Evidence Review, Urges ESC Input – TCTMD (free) AND Changing Evidence, Changing Practice – European Association of Cardio-Thoracic Surgery (free)
Related Commentary on Twitter
NEW: Percutaneous coronary angioplasty versus coronary artery bypass grafting in the treatment of unprotected left main stenosis: updated 5-year outcomes from the randomised, non-inferiority NOBLE trial https://t.co/T9a6n7CvFp pic.twitter.com/Mw2KdsBQfV
— The Lancet (@TheLancet) December 23, 2019
Randomized Trial: Angiotensin-II Receptor Blockade Reduces the Rate of Aortic Dilatation in Patients with Marfan Syndrome
12 Dec, 2019 | 08:24h | UTCInvited Commentary: Angiotensin-II receptor blockade in Marfan syndrome – The Lancet (free)
Related Commentary on Twitter
NEW—Irbesartan is associated with a reduction in the rate of aortic dilatation in children and young adults with #Marfansyndrome and could reduce the incidence of aortic complications: finding from AIMS, double-blind, placebo-controlled randomised trial https://t.co/uVUWOC062A pic.twitter.com/FPiph5RcJu
— The Lancet (@TheLancet) December 11, 2019
BBC Investigation on the Reporting of the EXCEL Trial Raises Concerns Over the Safety of Stents for Left Main Disease in Patients at Low Risk for Surgery
11 Dec, 2019 | 08:19h | UTCSurgeons withdraw support for heart disease advice – BBC (free)
YouTube Video: European guidelines on heart disease under review – BBC Newsnight (free)
See also: EACTS responds to BBC Newsnight’s investigation on the EXCEL trial – European Association for Cardio-Thoracic Surgery (free)
Commentary: EACTS Pulls Out of Left Main Guidelines After BBC Bombshell Alleging EXCEL Trial Cover-up – TCTMD (free)
Related Commentary on Twitter
Wow! Super 🔥🔥🔥🔥 breaking story!
Reanalysis of EXCEL using Universal Definition of MI would have changed results substantially.
Taggart may be vindicated.
H/t @MedCrisis @drjohnm https://t.co/Yu7qKuiBdV
— Venk Murthy MD PhD (@venkmurthy) December 9, 2019
ASH Guideline: Prevention of Venous Thromboembolism in Surgical Hospitalized Patients
5 Dec, 2019 | 11:29h | UTCRelated: European guidelines on perioperative venous thromboembolism prophylaxis – European Journal of Anaesthesiology (comprehensive resource on the subject) AND American Society of Hematology 2018 Guidelines for Management of Venous Thromboembolism: Prophylaxis for Hospitalized and Nonhospitalized Medical Patients (free)
Consensus Document: How to Prevent, Diagnose, and Treat Cardiac Implantable Electronic Device Infections
26 Nov, 2019 | 08:21h | UTC
#AHA19 – Randomized Trial: Phosphodiesterase 5 inhibitor Improves Exercise Capacity in Patients Who Have Undergone the Fontan Procedure
19 Nov, 2019 | 08:45h | UTCResults of the Fontan Udenafil Exercise Longitudinal (FUEL) Trial – Circulation (free for a limited period)
Commentaries: Teens with Heart Disease Improve Exercise Capacity in Large Clinical Trial – Children’s Hospital of Philadelphia (free) AND Pediatric drug trial finds benefit in teens with heart defect – NIH News Releases (free)
#AHA19 – Just Presented at the 2019 American Heart Association Annual Meeting
Related Commentary on Twitter
FUEL Trial- udenafil did not improve peak VO2, but did positively impact measures of exercise performance in pts w/FONTAN @PHNresearch @nih_nhlbi @HeartCare4Kids @ChildrensPhila #CircAHA19 #AHA19 #AHAJournals https://t.co/Kmt9GFASZR pic.twitter.com/WV0NITTg7y
— Circulation (@CircAHA) November 17, 2019
#AHA19 – [Not Published Yet] Landmark ISCHEMIA Trial: A Routine Invasive Strategy Does Not Reduce Cardiovascular Events in Patients with Stable Coronary Artery Disease
18 Nov, 2019 | 01:13h | UTCCommentaries: International Study of Comparative Health Effectiveness With Medical and Invasive Approaches – ISCHEMIA – American College of Cardiology (free) AND ISCHEMIA Trial Examines Invasive vs. Conservative Strategy in SIHD Patients – American College of Cardiology (free) AND ISCHEMIA: Invasive Strategy No Better Than Meds for CV Events – TCTMD (free) AND Surgery for Blocked Arteries Is Often Unwarranted, Researchers Find – The New York Times (free) AND ISCHEMIA Trial Finds No Evidence of Lower Cardiac Event Rates in Patients Treated with Heart Procedures, but Better Quality of Life – PR Newswire (free) AND Big study casts doubt on need for many heart procedures – Associated Press (free) AND Stents no better than drugs for many heart patients: U.S. study – Reuters (free) AND Stents, bypass surgery show no benefit in heart disease mortality rates among stable patients – Stanford Medicine (free)
#AHA19 – Just Presented at the 2019 American Heart Association Annual Meeting
#AHA19 – [Abstract Only] Randomized Trial: Early Surgery Improves Outcomes in Asymptomatic Patients with Very Severe Aortic Stenosis
18 Nov, 2019 | 01:09h | UTCEarly Surgery or Conservative Care for Asymptomatic Aortic Stenosis – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: RECOVERY Finds Early Surgery Beneficial For Asymptomatic Severe AS Patients – American College of Cardiology (free) AND Randomized Comparison of Early Surgery Versus Conventional Treatment in Very Severe Aortic Stenosis – RECOVERY – American College of Cardiology (free) AND Early Surgery Beats a Conservative Approach in Asymptomatic AS: RECOVERY – TCTMD (free)
#AHA19 – Just Presented at the 2019 American Heart Association Annual Meeting
Related Commentary on Twitter
At a median of 6 years of follow-up, operative mortality or CV death occurred less frequently in asymptomatic patients with very severe aortic stenosis who received early valve replacement surgery than in those conservatively managed. #AHA19 https://t.co/hcQeoRqseJ
— NEJM (@NEJM) November 16, 2019
Guidelines for the Diagnosis, Treatment and Prevention of Disseminated Mycobacterium chimaera Infection Following Cardiac Surgery with Cardiopulmonary Bypass
15 Nov, 2019 | 10:40h | UTC
Randomized Trial: Fibrinogen Concentrate vs. Cryoprecipitate for the Treatment of Bleeding in Cardiac Surgery
22 Oct, 2019 | 07:36h | UTCEffect of Fibrinogen Concentrate vs Cryoprecipitate on Blood Component Transfusion After Cardiac Surgery: The FIBRES Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Should Fibrinogen Concentrate Replace Cryoprecipitate in Cardiac Surgery? (free for a limited period)
Meta-Analysis: Antithrombotic Treatment after Coronary Artery Bypass Graft Surgery
11 Oct, 2019 | 09:43h | UTCCommentary: DAPT After CABG Better Than Aspirin Alone for Preventing Saphenous Graft Failure – NEJM Journal Watch (free)
Study: Cardiac Magnetic Resonance Stress Perfusion Imaging Offers Effective Cardiac Prognostication in Patients with Stable Chest Pain Syndromes
10 Oct, 2019 | 09:11h | UTC
2019 EACTS/EACTA/EBCP Guidelines on Cardiopulmonary Bypass in Adult Cardiac Surgery
4 Oct, 2019 | 08:11h | UTC
Enhanced Recovery After Cardiac Surgery (ERAS Cardiac) Recommendations: An Important First Step—But There Is Much Work to Be Done
4 Oct, 2019 | 08:01h | UTCOriginal Article: Enhanced Recovery After Surgery (ERAS) Guidelines for Perioperative Care in Cardiac Surgery (free guideline and commentary)
Systematic Review: Perioperative Beta‐blockers in Adults Undergoing Cardiac Surgery
24 Sep, 2019 | 08:12h | UTCPerioperative beta‐blockers for preventing surgery‐related mortality and morbidity in adults undergoing cardiac surgery – Cochrane Library (free)
Summary: Beta-blockers to prevent death or serious events after heart surgery – Cochrane Library (free)
Related: Perioperative beta‐blockers for preventing surgery‐related mortality and morbidity – Cochrane Library (free)
Prevention of Cardiac Surgery-Associated Acute Kidney Injury: A Review of Current Strategies
24 Sep, 2019 | 07:52h | UTC
Meta-Analysis: Transcatheter vs. Surgical Aortic Valve Replacement in Low-Risk Patients
20 Sep, 2019 | 08:07h | UTCTranscatheter Versus Surgical Aortic Valve Replacement in Low-Risk Patients – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Commentaries: Meta-Analysis of TAVR vs. SAVR in Low-Risk Patients – American College of Cardiology (free) AND TAVR Survival Surpasses SAVR in Low-Risk Patients: Meta-analysis – Medscape (free registration required)
“The one clear unknown that everyone points to is valve durability” (form Medscape)
“longer follow-up regarding valve degeneration will be needed to confirm TAVR as the preferred treatment for low-risk patients with severe AS.” (from American College of Cardiology)
[Abstract Only] Cohort Study: Complete vs. Staged Repair of Tetralogy of Fallot in Neonates
18 Sep, 2019 | 01:06h | UTCComplete vs. Staged Repair of Tetralogy of Fallot in Neonates – American College of Cardiology (free)
Original Study: 2-Year Outcomes After Complete or Staged Procedure for Tetralogy of Fallot in Neonates – Journal of the American College of Cardiology (link to abstract – $ for full-text)
#ESCCongress – [Abstract Only] Randomized Trial: PCI vs. CABG in Patients with Three-vessel or Left Main Coronary Artery Disease
3 Sep, 2019 | 01:24h | UTCPercutaneous coronary intervention versus coronary artery bypass grafting in patients with three-vessel or left main coronary artery disease: 10-year follow-up of the multicentre randomised controlled SYNTAX trial – The Lancet (link to abstract – $ for full-text)
Commentary: Bypass surgery and coronary stenting yield comparable 10-year survival – European Society of Cardiology (free)
Related Meta-Analysis: Mortality after coronary artery bypass grafting versus percutaneous coronary intervention with stenting for coronary artery disease (link to abstract) AND Percutaneous Coronary Intervention vs Coronary Artery Bypass Grafting in Patients With Left Main Coronary Artery Stenosis (free)
Related Commentary on Twitter
SYNTAX extended survival: 10yr all cause death PCI vs CABG:
❤️no significant difference in all cause death (24%CABG/27%PCI)
❤️CABG better than PCI for 3VD (21%CABG/28%PCI)
❤️no significant difference in LMS diseaseImpressive 94% FU.https://t.co/X4g9WgTBXI#ESCCongress pic.twitter.com/M7halGNnsv
— Sarah Hudson (@sarahhudsonuk) September 2, 2019