Cardiology (all articles) | Page 168 of 178 | Links Medicus Content Curation & Alerts in Medicine

#ESCCongress – 2017 ESC Guidelines on the Diagnosis and Treatment of Peripheral Arterial Diseases

27 Aug, 2017 | 20:10h | UTC

2017 ESC Guidelines on the Diagnosis and Treatment of Peripheral Arterial Diseases, in collaboration with the European Society for Vascular Surgery (ESVS): Document covering atherosclerotic disease of extracranial carotid and vertebral, mesenteric, renal, upper and lower extremity arteries (free) (RT @rafavidalperez see Tweet)

See also: #ESCCongress Slides (free PPT file)

#ESCCongress – Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease

27 Aug, 2017 | 20:06h | UTC

Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease – New England Journal of Medicine (free)

Editorial: Targeting Inflammation in Coronary Artery Disease (free)

Commentaries: Anti-Inflammatory Therapy for Atherosclerotic Disease: A Step Closer? – Physician’s First Watch (free) AND CANTOS: Anti-inflammatory Agent Canakinumab Modestly Reduces Major CVD Events – TCTMD (free) AND CANTOS Validates Role Of Inflammation In Heart Disease – Cardiobrief (free)

“This widely anticipated study delivered some modestly positive results (fewer nonfatal MIs), some worrisome results (increased fatal infections), and some unexpected results (fewer cancer deaths)” (from Physician’s First Watch).

#ESCCongress – 2017 ESC focused update on dual antiplatelet therapy in coronary artery disease

27 Aug, 2017 | 20:09h | UTC

2017 ESC focused update on dual antiplatelet therapy in coronary artery disease developed in collaboration with EACTS (free) (RT @rafavidalperez see Tweet)

See also: #ESCCongress Slides (free PPT file)

#ESCCongress – Rivaroxaban with or without Aspirin in Stable Cardiovascular Disease

27 Aug, 2017 | 20:08h | UTC

Rivaroxaban with or without Aspirin in Stable Cardiovascular Disease – New England Journal of Medicine (free)

Editorial by Dr. Eugene Braunwald: An Important Step for Thrombocardiology (free)

Commentaries: Cardiovascular Outcomes for People Using Anticoagulation Strategies – COMPASS – American College of Cardiology, Latest in Cardiology (free) AND COMPASS: Does Rivaroxaban Plus Aspirin Improve CV Outcomes in Patients With Stable Atherosclerotic Vascular Disease or PAD? – ACC News Story (free) AND Rivaroxaban, Aspirin, or Both in Stable Coronary Disease – Physician’s First Watch (free)

The primary outcome (composite of cardiovascular death, stroke, or myocardial infarction) occurred in fewer patients in the rivaroxaban-plus-aspirin group than in the aspirin-alone group (4.1% vs. 5.4% / Absolute risk difference = 1.3% / NNT = 76), but major bleeding events occurred in more patients in the rivaroxaban-plus-aspirin group (3.1% vs. 1.9% / Absolute risk difference = 1.2 / NNH = 83).

#ESCCongress – Incidence of Previously Undiagnosed Atrial Fibrillation Using Insertable Cardiac Monitors in a High-Risk Population

27 Aug, 2017 | 20:03h | UTC

Incidence of Previously Undiagnosed Atrial Fibrillation Using Insertable Cardiac Monitors in a High-Risk Population: The REVEAL AF Study (free)

Commentaries: What Do Implanted Cardiac Monitors Reveal About Atrial Fibrillation? – JAMA Cardiology (free) AND REVEAL AF: Incidence of AFib Could Be Substantial in Older Patients With Stroke Risk Factors – American College of Cardiology, Latest in Cardiology (free) AND Detection of Undiagnosed AF Using Insertable Cardiac Monitors – American College of Cardiology, Latest in Cardiology (free)

Implanted Cardiac Monitors showed the incidence of intermittent atrial fibrillation is extremely common among older individuals with stroke risk factors, but the clinical significance of these findings (do they need to be anticoagulated??) remains to be determined by further trials.

“Previous long-term monitoring studies have suggested that patients with short episodes of subclinical AF have a lower risk of stroke compared with traditional clinical AF, which raises important questions about the risk-benefit ratio of anticoagulation in this setting” (from Latest in Cardiology).

#ESCCongress – Catheter ablation improves outcomes in patients with heart failure and atrial fibrillation

27 Aug, 2017 | 20:03h | UTC

Catheter ablation improves outcomes in patients with heart failure and atrial fibrillation (CASTLE-AF) (free)

Commentary: CASTLE-AF: Catheter Ablation vs. Conventional Therapy For Patients With AFib and LV Dysfunction – American College of Cardiology, Latest in Cardiology (free)

The study has not been published yet, but the results suggest that patients with symptomatic paroxysmal or persistent AF and heart failure with ejection fraction less than 35% may have a better outcome with catheter ablation.

#ESCCongress – CI Versus CABG in Patients With Type 1 Diabetes and Multivessel Disease

27 Aug, 2017 | 20:02h | UTC

CI Versus CABG in Patients With Type 1 Diabetes and Multivessel Disease – Journal of The American College of Cardiology (link to abstract – $ for full-text)

Commentaries: Patients With Type 1 Diabetes and Multivessel Disease Have Greater Benefit From CABG Than PCI – American College of Cardiology, Latest in Cardiology (free) AND Revascularization in Patients With Type 1 Diabetes – American College of Cardiology, Latest in Cardiology (free)

CABG Appears Superior to PCI for Patients With Type 1 Diabetes, Multivessel Disease – TCTMD (free)

“The observational findings support existing recommendations favoring surgical revascularization in patients with diabetes” (from TCTMD).

Study: Gastrointestinal Safety of Direct Oral Anticoagulants

26 Aug, 2017 | 16:46h | UTC

Gastrointestinal Safety of Direct Oral Anticoagulants: A Large Population-Based Study – Gastroenterology (free)

Commentary: Which NOACS are riskiest for gastrointestinal bleeding? – Pharmacy News (free)

Source: ACP Journal Club ($)

Observational study suggests Apixaban may be associated with a more favorable gastrointestinal safety profile. Further randomized trials are needed to confirm these findings.

Review: Light-chain cardiac amyloidosis

26 Aug, 2017 | 16:08h | UTC

Light-chain cardiac amyloidosis: strategies to promote early diagnosis and cardiac response – Heart (free)

Review: Hybrid repair of aortic arch aneurysms

26 Aug, 2017 | 15:43h | UTC

Hybrid repair of aortic arch aneurysms: a comprehensive review – Journal of Thoracic Disease (free)

Guideline: treatment of hypertension in people with diabetes

24 Aug, 2017 | 23:17h | UTC

Diabetes and Hypertension: A Position Statement by the American Diabetes Association (free) (RT @Abraham_RMI and @ADA_Journals see Tweet)

Commentary: ADA Offers Position Statement on Diabetes and Hypertension – AJMC (free)

“the guideline continues the advice that most patients with diabetes should be treated to a blood pressure goal of <140/90 mm Hg; a goal of <130/80 can be considered for patients who have other cardiovascular risk factors” (from AJMC)

Report: Global Burden of Rheumatic Heart Disease

24 Aug, 2017 | 23:16h | UTC

Global, Regional, and National Burden of Rheumatic Heart Disease, 1990–2015 – New England Journal of Medicine (free)

Editorial: Rheumatic Heart Disease — An Iceberg in Tropical Waters (free) (RT @NEJM see Tweet with interesting table)

Quick Take Video Summary: What is the Global Burden of Rheumatic Heart Disease? (free)

Commentary: Death rates from rheumatic heart disease falling since 1990 – Institute for Health Metrics and Evaluation (free)

NT-proBNP not helpful for heart failure drug titration

24 Aug, 2017 | 20:34h | UTC

Effect of Natriuretic Peptide–Guided Therapy on Hospitalization or Cardiovascular Mortality in High-Risk Patients With Heart Failure and Reduced Ejection Fraction: A Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)

Commentaries: Natriuretic Peptide-Guided Therapy No Better Than Usual Care in Heart Failure Patients – Physician’s First Watch (free) AND NT-proBNP Tx Disappoints for HF Drug Titration – MedPage Today (free registration required)

Review: Cost-Effectiveness of Cardiotoxicity Monitoring

22 Aug, 2017 | 19:01h | UTC

Cost-Effectiveness of Cardiotoxicity Monitoring – American College of Cardiology, Latest in Cardiology (free)

Study: Particulate Matter Exposure and Stress Hormone Levels

22 Aug, 2017 | 18:36h | UTC

Particulate Matter Exposure and Stress Hormone Levels: A Randomized, Double-Blind, Crossover Trial of Air Purification – Circulation (free)

Commentaries: Air pollution ups stress hormones, alters metabolismo – Reuters (free) AND AND Novel Study Shows How Air Pollution Increases CVD Risk – MedPage Today (free registration required) AND Air pollution linked to cardiovascular disease; air purifiers may lessen impact – American Heart Association, via Science Daily (free)

Study: Gastrointestinal safety of celecoxib versus naproxen in patients with cardiothrombotic diseases and arthritis after upper gastrointestinal bleeding

22 Aug, 2017 | 15:19h | UTC

Gastrointestinal safety of celecoxib versus naproxen in patients with cardiothrombotic diseases and arthritis after upper gastrointestinal bleeding (CONCERN): an industry-independent, double-blind, double-dummy, randomised trial – The Lancet (link to abstract – $ for full-text)

Source: ACP Journal Club

In this study, patients at high risk of both cardiovascular and gastrointestinal events who required concomitant aspirin and NSAID, celecoxib associated with a proton pump inhibitor led to less recurrent gastrointestinal bleeding when compared to naproxen associated with a proton pump inhibitor (5.6% vs 12.3%).