Cardiology (all articles)
Meta-analysis: Drugs in heart failure with preserved ejection fraction
31 Aug, 2017 | 20:33h | UTCCommentary: Heart Failure with Preserved Ejection Fraction: Treatments Compared – MPR (free)
Source: ACP Journal Wise ($)
This study suggests a reduction in all-cause mortality with beta-blocker therapy in patients with heart failure with preserved ejection fraction. The authors recommend further trials to confirm the benefits of beta-blockers in this patient group.
Review: Acute aortic dissection: pathogenesis, risk factors and diagnosis
31 Aug, 2017 | 20:28h | UTCAcute aortic dissection: pathogenesis, risk factors and diagnosis – Swiss Medical Weekly (free)
Study: Impact of Obesity on Intensive Care Unit Resource Utilization After Cardiac Operations
31 Aug, 2017 | 16:31h | UTCImpact of Obesity on Intensive Care Unit Resource Utilization After Cardiac Operations – The Annals of Thoracic Surgery (link to abstract – $ for full-text)
Commentaries: Obese cardiac patients a drain on ICU resources – Cardiovascular Business (free) AND Obese Cardiac Surgery Patients a Burden on ICU Resources – TCTMD (free) AND Post–Cardiac Surgery ICU Usage Rises With Increasing Obesity – Medscape (free registration required)
Systematic Review: Complete versus culprit-only revascularisation in ST elevation myocardial infarction with multi-vessel disease
31 Aug, 2017 | 16:11h | UTCOriginal article: Complete versus culprit-only revascularisation in ST elevation myocardial infarction with multi-vessel disease – Cochrane Library (link to abstract – $ for full-text)
Study: Cognitive Function in a Randomized Trial of Evolocumab
31 Aug, 2017 | 15:35h | UTCCognitive Function in a Randomized Trial of Evolocumab – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Cholesterol-Lowering Drug Evolocumab Doesn’t Seem to Impair Cognition – Physician’s First Watch (free)
“The authors caution that most people take cholesterol-lowering medications for decades, and this was a much shorter follow-up period” (from Physician’s First Watch).
Study: Medical Students Fall Short on Blood Pressure Check Challenge
30 Aug, 2017 | 20:20h | UTCMedical News & Perspectives: Medical Students Fall Short on Blood Pressure Check Challenge – JAMA (free)
Original Article: Medical students and measuring blood pressure: Results from the American Medical Association Blood Pressure Check Challenge – The Journal of Clinical Hypertension (free)
“Only 1 out of 159 medical students correctly performed all 11 elements in a BP check challenge w simulated patients” (RT @JAMA_current see Tweet)
#ESCCongress – Observational Study: Clopidogrel or ticagrelor in acute coronary syndrome patients treated with newer-generation drug-eluting stents
30 Aug, 2017 | 19:01h | UTC#ESCCongress – Clopidogrel or ticagrelor in acute coronary syndrome patients treated with newer-generation drug-eluting stents: CHANGE DAPT – EuroIntervention (link to abstract – $ for full-text)
Commentaries: Rethinking dual antiplatelet guidelines in acute coronary syndrome? (CHANGE-DAPT) – ESC Press Releases (free) AND Ticagrelor for DAPT Again Questioned in Current Era of PCI for ACS: CHANGE DAPT – Medscape (free registration required)
CHANGE DAPT: Study Contests Benefit of Ticagrelor Over Clopidogrel After PCI in ACS – TCTMD (free)
#ESCCongress – Cohort Study: Fruit, vegetable, and legume intake, and cardiovascular disease and deaths
30 Aug, 2017 | 18:32h | UTC#ESCCongress – Fruit, vegetable, and legume intake, and cardiovascular disease and deaths in 18 countries (PURE): a prospective cohort study – The Lancet (link to abstract – $ for full-text)
Commentaries: Reassessing the benefits of plant-based eating (PURE) – ESC Press Release (free) Fruit, Vegetable, Legume Intake and CVD Events – American College of Cardiology, Latest in Cardiology (free) AND Life-saving fruit and vegetable diet need only be three portions – study – The Guardian (free) AND Less Is More? Health Benefits of Fruits, Vegetables, and Legumes Seen at Lower Intake Levels – TCTMD (free)
#ESCCongress – Study: Underweight associated with highest mortality and costs after cardiac catheterization
30 Aug, 2017 | 18:30h | UTCUnderweight associated with highest mortality and costs after cardiac catheterization (free) (the results have not been published yet)
Commentaries: Underweight and Overlooked: Low BMI Patients May Be Highest-Risk Post-PCI – TCTMD (free) AND Underweight Patients Fare Worse After Heart Catheterization – Medscape (free registration required) AND ESC 2017: Underweight Is Associated With Highest Mortality and Costs After Cardiac Catheterization – PracticeUpdate (free registration required)
#ESCCongress – Study confirms safety of rapid algorithm to rule-out and rule-in myocardial infarction
30 Aug, 2017 | 18:31h | UTCStudy confirms safety of rapid algorithm to rule-out and rule-in myocardial infarction – ESC Press Release (free) (the results have not been published yet)
Commentary: ESC Rapid Rule-In, Rule-Out Algorithm for NSTEMI Safe, Accurate – Medscape (free registration required)
Related guideline: 2015 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation (free) AND Other Resources (free)
#ESCCongress – Cohort Study: Associations of fats and carbohydrate intake with cardiovascular disease and mortality
30 Aug, 2017 | 18:33h | UTC#ESCCongress – Associations of fats and carbohydrate intake with cardiovascular disease and mortality in 18 countries from five continents (PURE): a prospective cohort study – The Lancet (link to abstract – $ for full-text)
Commentaries: Revisiting dietary fat guidelines? (PURE) – ESC Press Release (free) AND PURE Investigators: Rethink Diet Guidance to Plug More Fats, Fewer Carbs – TCTMD (free) AND International study shows moderate consumption of fats and carbohydrates best for health – McMaster University, via EurekAlert (free) AND PURE: Findings Could Have Implications For Global Dietary Guidelines – ACC News Story (free) AND Huge Diet Study Questions Conventional Wisdom About Carbs And Fats – Cardiobrief (free)
#ESCCongress – Study: Effects of Anacetrapib in Patients with Atherosclerotic Vascular Disease
30 Aug, 2017 | 18:29h | UTCCommentaries: Anacetrapib REVEALs ‘Modest’ Effect on Cardiovascular Outcomes – Medscape (free registration required) AND Anacetrapib Finds (Modest) Success Where All Other CETP Inhibitors Failed – TCTMD (free) AND REVEAL Revealed: A Slightly Positive CETP Inhibitor Trial – Cardiobrief (free)
Interesting new drug, but with modest benefits. During the median follow-up period of 4.1 years, the primary outcome occurred in fewer patients in the anacetrapib group than in the placebo group (10.8% vs. 11.8% / absolute risk difference = 1%, meaning 100 patients would have to be treated for 4.1 years to benefit 1 patient)
#ESCCongress – Study: Automatic external defibrillators save lives in amateur sports and fitness centres
30 Aug, 2017 | 18:28h | UTCAutomatic external defibrillators save lives in amateur sports and fitness centres (free) (the results have not been published yet)
“Neurologically intact survival was 93% for patients treated with an onsite Automatic external defibrillator (AED) compared to 9% without an AED”
Review: Pulmonary Hypertension
30 Aug, 2017 | 18:05h | UTCPulmonary Hypertension – Deutsches Ärzteblatt international (free)
Source: Critical Care Reviews Topic of The Week
Study: Comparison of Coronary CT Angiography, SPECT, PET, and Hybrid Imaging for Diagnosis of Ischemic Heart Disease Determined by Fractional Flow Reserve
30 Aug, 2017 | 18:02h | UTCCommentaries: SPECT, PET, and CTA—Acronyms or Better Imaging? – JAMA Cardiology (free) PET More Accurate for Diagnosing CAD Than SPECT and CT Angiography: PACIFIC Study – TCTMD (free) PET Dominates in Non-invasive CAD Detection Accuracy – MedPage Today (free)
#ESCCongress – Study: Oxygen Therapy in Suspected Acute Myocardial Infarction
29 Aug, 2017 | 15:15h | UTCOxygen Therapy in Suspected Acute Myocardial Infarction – New England Journal of Medicine (free)
Editorial: Is Oxygen Therapy Beneficial in Acute Myocardial Infarction? Simple Question, Complicated Mechanism, Simple Answer (free)
Commentaries: Oxygen therapy does not improve survival in patients with heart attack symptoms (DETO2X-AMI) – ESC Press Releases (free) AND Supplemental Oxygen Provides No Benefit to Patients With Suspected MI: DETO2X-AMI – TCTMD (free) AND Suspected MI and Normal Oxygen Saturation? Don’t Bother with Supplemental Oxygen – Physician’s First Watch (free)
#ESCCongress – Study: Screening for vascular disease saves one life for every 169 patients assessed
29 Aug, 2017 | 15:14h | UTCPopulation screening and intervention for vascular disease in Danish men (VIVA): a randomised controlled trial – The Lancet (link to abstract – $ for full-text)
Commentaries: Screening for vascular disease saves one life for every 169 patients assessed (VIVA) – ESC Press Releases (free) AND VIVA: Could Population-Wide Screening Trial for AAA, PAD, and Hypertension Save Lives at Low Cost? – TCTMD (free) AND VIVA: Overall Mortality Significantly Reduced Among Older Men Receiving Triple Vascular Screening – American College of Cardiology, Latest in Cardiology (free)
#ESCCongress – Study: drug-resistant hypertension – old drugs work best
29 Aug, 2017 | 15:13h | UTCPATHWAY-2 uncovers main cause of drug-resistant hypertension, finds old drugs work best – ESC Press Releases (free) (the results have not been published yet)
Commentary: Prevention And Treatment of Hypertension With Algorithm based therapY-2 – PATHWAY-2 – American College of Cardiology, Latest in Cardiology (free)
#ESCCongress – Study: Bag-mask ventilation fails to improve on endotracheal intubation in cardiac arrest
29 Aug, 2017 | 15:11h | UTCBag-mask ventilation fails to improve on endotracheal intubation in cardiac arrest (CAAM) – ESC Press Releases (free) (the results have not been published yet)
Commentary: CAAM: Is Bag-Mask Ventilation Superior to ETI During CPR? – American College of Cardiology, Latest in Cardiology (free)
#ESCCongress – Study: Risk factor driven upstream atrial fibrillation therapy improves sinus rhythm maintenance
29 Aug, 2017 | 15:08h | UTCRisk factor driven upstream atrial fibrillation therapy improves sinus rhythm maintenance (RACE 3) – ESC Press Releases (free) (the results have not been published yet)
Commentaries: Broad, Early AF Risk-Factor Intervention Preserves Sinus Rhythm: RACE-3 – Medscape (free registration required) AND Routine vs. Aggressive upstream rhythm Control for prevention of Early persistent atrial fibrillation in heart failure study – RACE 3 – American College of Cardiology, Latest in Cardiology (free)
#ESCCongress – Study: The Prognostic Value of Coronary Artery Calcium
29 Aug, 2017 | 15:07h | UTCThe Prognostic Value of Coronary Artery Calcium in the PROMISE Study – Circulation (free PDF)
Editorial: Computed Tomography or Functional Stress Testing for the Prediction of Risk: Can I Have My Cake and Eat It? (free PDF)
Commentary: Prospective Multicenter Imaging Study for Evaluation of Chest Pain – PROMISE – American College of Cardiology, Latest in Cardiology (free)
#ESCCongress – Study: Closure of left atrial appendage during heart surgery protects the brain
29 Aug, 2017 | 15:09h | UTCClosure of left atrial appendage during heart surgery protects the brain (LAACS) – ESC Press Releases (free) (the results have not been published yet)
Commentary: LAACS: LAA Closure May Protect Against Long-Term Cerebral Ischemic Events – American College of Cardiology, Latest in Cardiology (free)
#ESCCongress – 2017 ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation
27 Aug, 2017 | 20:11h | UTC2017 ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation: The Task Force for the management of acute myocardial infarction in patients presenting with ST-segment elevation of the European Society of Cardiology (ESC) (free) (RT @rafavidalperez see Tweet)
Commentary: ESC Updates Guidelines for Treating STEMI Patients – TCTMD (free)
See also: #ESCCongress Slides (free PPT file)
#ESCCongress – 2017 ESC/EACTS Guidelines for the management of valvular heart disease
27 Aug, 2017 | 20:12h | UTC2017 ESC/EACTS Guidelines for the management of valvular heart disease (free) (RT @rafavidalperez see Tweet)
Commentary: European Societies Issue New Valvular Heart Disease Guidelines, With Important Shifts – TCTMD (free)
See also: #ESCCongress Slides (free PPT file)
#ESCCongress – Dual Antithrombotic Therapy with Dabigatran after PCI in Atrial Fibrillation
27 Aug, 2017 | 20:07h | UTCCommentaries: Randomized Evaluation of Dual Antithrombotic Therapy With Dabigatran vs. Triple Therapy With Warfarin in Patients With Nonvalvular Atrial Fibrillation Undergoing Percutaneous Coronary Intervention – RE-DUAL PCI – American College of Cardiology, Latest in Cardiology (free) Dual Antithrombotic Therapy Is Safe for Patients with AF and a New Stent – Physician’s First Watch (free) AND When two is better than three: Dual antithrombotic therapy cuts bleeding risk – Brigham and Women’s Hospital, via ScienceDaily (free)
“In summary, several lines of evidence now suggest that it is safe to treat atrial fibrillation patients who undergo coronary revascularization with anticoagulation (warfarin studied in WOEST, rivaroxaban studied in PIONEER AF-PCI, dabigatran studied in RE-DUAL PCI) and clopidogrel monotherapy” (from American College of Cardiology, Latest in Cardiology).