Cardiology (all articles)
Fast and accurate view classification of echocardiograms using deep learning
30 Mar, 2018 | 04:30h | UTCFast and accurate view classification of echocardiograms using deep learning – npj Digital Medicine (free)
Commentaries: AI is Quicker, More Effective Than Humans in Analyzing Heart Scans – University of California San Francisco (free) AND Study: AI faster, more accurate than humans at analyzing heart scans – UPI (free) AND AI model 98% accurate in ECG classification—outperforming cardiologists – Health Imaging (free)
Meta-Analysis: Patent foramen ovale closure vs. medical therapy for cryptogenic stroke
30 Mar, 2018 | 04:27h | UTC“5-study EHJ meta analysis confirms value of PFO closure after cryptogenic stroke. “Number Needed to Close”: 178 pts to prevent one stroke over 1 year. Size matters (no effect for small shunts, “NNC” 96 for large shunts)” (via @Steph_Achenbach see Tweet)
The Effect of Door-to-Diuretic Time on Clinical Outcomes in Patients With Acute Heart Failure
30 Mar, 2018 | 04:09h | UTCCommentaries: Quicker Diuretics Not Associated With Better Outcomes in Acute Heart Failure – TCTMD (free) AND Door-to-Diuretic Time in Acute Heart Failure – American College of Cardiology, Latest in Cardiology (free) AND Door-to-diuretic time didn’t affect mortality from heart failure in Korean registry – ACP Hospitalist (free)
“Overall, there isn’t strong evidence of benefit from early use of diuretics and “the overriding consideration should remain ‘get it right’ rather than ‘do it fast,’” the editorial concluded”. (from ACP)
Long-term Thromboembolic Risk in Patients With Postoperative Atrial Fibrillation After Coronary Artery Bypass Graft Surgery and Patients With Nonvalvular Atrial Fibrillation
30 Mar, 2018 | 04:05h | UTCLong-term Thromboembolic Risk in Patients With Postoperative Atrial Fibrillation After Coronary Artery Bypass Graft Surgery and Patients With Nonvalvular Atrial Fibrillation – JAMA Cardiology (free for a limited period)
Commentaries: Postoperative A-fib Not as Bad as Nonsurgical A-fib for Thromboembolism – TCTMD (free) AND Fib after CABG linked to minimal long-term stroke risk – Cardiovascular Business (free)
Viewpoint: Individualizing Blood Pressure Targets for People With Diabetes and Hypertension
30 Mar, 2018 | 03:48h | UTCViewpoint: Individualizing Blood Pressure Targets for People With Diabetes and Hypertension: Comparing the ADA and the ACC/AHA Recommendations – JAMA (free for a limited period)
Association of Placebo, Indomethacin, Ibuprofen, and Acetaminophen With Closure of Hemodynamically Significant Patent Ductus Arteriosus in Preterm Infants
30 Mar, 2018 | 03:34h | UTCAssociation of Placebo, Indomethacin, Ibuprofen, and Acetaminophen With Closure of Hemodynamically Significant Patent Ductus Arteriosus in Preterm Infants: A Systematic Review and Meta-analysis – JAMA (link to abstract – $ for full-text)
Commentaries: Meta-Analysis: High-Dose Ibuprofen Tops for Closing Preemie PDA – MedPage Today (free registration required)
Social isolation and loneliness as risk factors for myocardial infarction, stroke and mortality
30 Mar, 2018 | 03:30h | UTCCommentaries: Loneliness itself appears not to raise risk of heart attack/stroke – OnMedica (free) AND Association Between Loneliness, CV Events Often Explained by Conventional Risk Factors – Physician’s First Watch (free)
Guideline: Arrhythmias in congenital heart disease
30 Mar, 2018 | 03:07h | UTC
For hypertension and diabetes, lower treatment targets not necessarily better
23 Mar, 2018 | 02:47h | UTCRelated: AAFP Decides to Not Endorse AHA/ACC Hypertension Guideline (free) AND ACC/AHA Hypertension Guideline: What Is New? What Do We Do? – American Family Physician (free) AND Hemoglobin A1c Targets for Glycemic Control With Pharmacologic Therapy for Nonpregnant Adults With Type 2 Diabetes Mellitus: A Guidance Statement Update From the American College of Physicians (free)
Cardiology World Erupts Into Controversy Over Change In Major Clinical Trial
23 Mar, 2018 | 02:49h | UTCCardiology World Erupts Into Controversy Over Change In Major Clinical Trial – Cardiobrief (free)
Related Article: Moving the Goalposts Into Unblinded Territory – Circulation: Cardiovascular Quality and Outcomes (free)
Practical Guide on the use of non-vitamin K antagonist oral anticoagulants in patients with atrial fibrillation
23 Mar, 2018 | 02:46h | UTCThe 2018 European Heart Rhythm Association Practical Guide on the use of non-vitamin K antagonist oral anticoagulants in patients with atrial fibrillation – European Heart Journal (free for a limited period)
News release: New EHRA Practical Guide on non-vitamin K antagonist oral anticoagulants launched (free)
Associations of Monounsaturated Fatty Acids From Plant and Animal Sources With Total and Cardiovascular Mortality Risk
23 Mar, 2018 | 02:44h | UTCAssociations of Monounsaturated Fatty Acids From Plant and Animal Sources With Total and Cardiovascular Mortality Risk – Circulation (link to abstract – presented at the American Heart Association’s Epidemiology and Prevention | Lifestyle and Cardiometabolic Health Scientific Sessions 2018)
Commentaries: Mono-unsaturated fats from plants, not animals may reduce risk of death from heart disease and other causes – AHA / ASA Newsroom (free) AND These plant-based fats could help you live longer – Medical News Today (free)
Expert consensus on arrhythmias and cognitive function
23 Mar, 2018 | 02:36h | UTCCommentary: New Expert Statement on Arrhythmias and Cognitive Function – Medscape (free registration required)
Diastolic blood pressure and adverse outcomes in patients with heart failure with preserved ejection fraction who are treated for hypertension
23 Mar, 2018 | 02:34h | UTCDiastolic Blood Pressure and Adverse Outcomes in the TOPCAT (Treatment of Preserved Cardiac Function Heart Failure With an Aldosterone Antagonist) Trial – Journal of the American Heart Association (free for a limited period)
“DBP values ≥90 and <60 mm Hg are associated with a significant risk of adverse outcomes in patients with heart failure with preserved ejection fraction who are treated for hypertension”.
Meta-Analysis: Blood pressure-lowering treatment strategies based on cardiovascular risk versus blood pressure
23 Mar, 2018 | 01:57h | UTCRelated study with similar conclusions: Impact of Cardiovascular Risk on the Relative Benefit and Harm of Intensive Treatment of Hypertension – Journal of the American College of Cardiology (link to abstract – $ for full-text)
“An intelligent approach towards blood pressure management: by the individual’s risk instead of just their measurements” (via @EricTopol see Tweet)
Research: Burden of cardiovascular risk factors and cardiovascular disease in childhood cancer survivors
23 Mar, 2018 | 01:56h | UTCCommentaries: Survivors of childhood cancer are at great risk of heart problems in adulthood – eCancerNews (free) AND Higher heart risk for survivors of childhood cancer – OnMedica (free)
Related study: The cumulative burden of surviving childhood cancer: an initial report from the St Jude Lifetime Cohort Study (SJLIFE) – The Lancet (link to abstract – $ for full-text)
Related Guidelines and Reviews: Prevention and Monitoring of Cardiac Dysfunction in Survivors of Adult Cancers: American Society of Clinical Oncology Clinical Practice Guideline (free) AND 2016 ESC Position Paper on cancer treatments and cardiovascular toxicity developed under the auspices of the ESC Committee for Practice Guidelines (free) AND Canadian Cardiovascular Society Guidelines for Evaluation and Management of Cardiovascular Complications of Cancer Therapy (free) AND Cardiotoxicity of anticancer treatments: Epidemiology, detection, and management – CA: A Cancer Journal for Clinicians (free)
Research: associations of different adiposity measures with the incidence of cardiovascular disease
23 Mar, 2018 | 01:48h | UTCCommentaries: New study casts further doubt on the idea that you can be ‘fat and fit’ – NHS Choices (free) AND A ‘Sweet Spot’ for Heart Health – The New York Times (10 articles per month are free)
Viewpoint: Individualizing Blood Pressure Targets for People With Diabetes and Hypertension
22 Mar, 2018 | 23:43h | UTCViewpoint: Individualizing Blood Pressure Targets for People With Diabetes and Hypertension: Comparing the ADA and the ACC/AHA Recommendations – JAMA (free for a limited period)
2018 ESC Guidelines for the diagnosis and management of syncope
19 Mar, 2018 | 13:12h | UTC2018 ESC Guidelines for the diagnosis and management of syncope – European Heart Journal (free for a limited period)
Related guideline: 2017 ACC/AHA/HRS Guideline for the Evaluation and Management of Patients With Syncope: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines, and the Heart Rhythm Society (free)
Cluster-Randomized Trial of Blood-Pressure Reduction in Black Barbershops
16 Mar, 2018 | 03:37h | UTC#ACC18 – Cluster-Randomized Trial of Blood-Pressure Reduction in Black Barbershops – New England Journal of Medicine (free for a limited period)
Commentaries: Barbershop-Based Intervention Leads to Blood Pressure Reductions in African-American Men – American College of Cardiology (free) AND Mixing Haircuts and Hypertension Rx a ‘Home Run’ for Blood Pressure Control – TCTMD (free)
“Among black male barbershop patrons with uncontrolled hypertension, health promotion by barbers resulted in larger blood-pressure reduction when coupled with medication management in barbershops by specialty-trained pharmacists”.
Research: Carvedilol for Prevention of Chemotherapy Related Cardiotoxicity
16 Mar, 2018 | 03:38h | UTC#ACC18 – Carvedilol for Prevention of Chemotherapy Related Cardiotoxicity – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Commentaries: Beta Blocker Shows Mixed Results in Protecting Against Chemo-Induced Heart Damage – American College of Cardiology (free) AND Carvedilol Effect in Preventing Chemotherapy Induced CardiotoxicitY – CECCY – American College of Cardiology (free)
Related study from #ACC18: Heart Drugs Prevented Cardiotoxicity in Breast Cancer Treated With Anthracycline and Trastuzumab – American College of Cardiology (free)
“According to the CECCY trial, carvedilol had no effect on left ventricular function in breast cancer patients treated w/ doxorubicin, but did result in a reduction in troponin I levels & diastolic dysfunction”. (via @ACCinTouch see Tweet)
Research: Low-Dose ‘Triple Pill’ Lowers Blood Pressure More Than Usual Care
16 Mar, 2018 | 03:36h | UTC#ACC18 – Low-Dose ‘Triple Pill’ Lowers Blood Pressure More Than Usual Care – American College of Cardiology (free) AND Low-Dose, Three-Drug Polypill TRIUMPHs for Blood Pressure – TCTMD (free)
Did a pricey cholesterol-lowering drug really reduce deaths, as headlines claim?
16 Mar, 2018 | 03:33h | UTCSee original article and commentaries in our March 12th issue (see #2)
The ODYSSEY Trial Ends Well— But Will It Be Enough?
16 Mar, 2018 | 03:32h | UTC#ACC18 – The ODYSSEY Trial Ends Well— But Will It Be Enough? – Cardiobrief (free) AND Ten Quick Thoughts on ODYSSEY – John Mandrola, via Medscape (free registration required)
“An absolute risk reduction of 1.6% in the primary endpoint translates to a number needed to treat of 64. Using the current price of $14,500 per year, Kaul calculated that preventing one event over the trial period of almost 3 years would cost about $2.6 million” (via John Mandrola). This study was presented at #ACC18 and has not been published yet. Among the many commentaries, these two were selected for a balanced point of view.
Research: Effect of Loading Dose of Atorvastatin Prior to Planned Percutaneous Coronary Intervention
16 Mar, 2018 | 03:22h | UTC#ACC18 – Effect of Loading Dose of Atorvastatin Prior to Planned Percutaneous Coronary Intervention on Major Adverse Cardiovascular Events in Acute Coronary Syndrome: The SECURE-PCI Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Lipid Lowering in Acute Coronary Syndrome: Is Treatment Early Enough? (free for a limited period)
Commentaries: Statins Evaluation in Coronary Procedures and Revascularization – SECURE-PCI – American College of Cardiology (free) AND No Benefits Likely with Very Early Statins in ACS Patients – MedPage Today (free registration required) AND SECURE-PCI Comes Up Short for Statin Preloading in ACS Patients – TCTMD (free)