Cardiology (all articles)
Randomized Trial: Preoperative Angiotensin-Converting Enzyme Inhibition and Outcomes
3 Aug, 2018 | 11:42h | UTCCommentary: Omitting ACE inhibitor before surgery reduced intraoperative hypotension, study finds – ACP Hospitalist (free)
Meta-Analysis: Efficacy and Safety of Further Lowering of LDL Cholesterol in Patients Starting With Very Low Levels
3 Aug, 2018 | 11:38h | UTCEfficacy and Safety of Further Lowering of Low-Density Lipoprotein Cholesterol in Patients Starting With Very Low Levels: A Meta-analysis – JAMA Cardiology (free for a limited period)
Author Interview: Efficacy and Safety of Further Lowering of LDL Cholesterol in Patients Starting With Very Low Levels (free)
Evidence Synopsis: Aspirin Plus Clopidogrel vs Aspirin Alone for Patients at High Risk for Cardiovascular Events
3 Aug, 2018 | 11:36h | UTCAspirin Plus Clopidogrel vs Aspirin Alone for Preventing Cardiovascular Events Among Patients at High Risk for Cardiovascular Events – JAMA (free for a limited period)
“Clopidogrel+ASA: Reduced risk for MI and ischemic stroke – Increased risk for major bleeding compared with aspirin alone. Combined therapy is NOT associated with lower mortality.” (via @ehlJAMA see Tweet)
Consensus Statement: Antithrombotic Therapy in Patients With Atrial Fibrillation Treated With Oral Anticoagulation Undergoing PCI
3 Aug, 2018 | 11:30h | UTCCommentary: New Consensus Statement: NOAC and Clopidogrel for Most A-fib Patients Treated With PCI – TCTMD (free)
Study: Association of Statin Exposure With Idiopathic Inflammatory Myositis
3 Aug, 2018 | 11:29h | UTCAssociation of Statin Exposure With Histologically Confirmed Idiopathic Inflammatory Myositis in an Australian Population – JAMA Internal Medicine (link to abstract – $ for full-text)
Commentaries: Rare Inflammatory Muscle Inflammation Increased With Statin Exposure – MedicalResearch.com (free) AND Statin Associated with an Increase in Inflammatory Myopathy – RheumNow (free) AND Statin use may increase risk for idiopathic inflammatory myositis – Healio (free registration required)
AHA Scientific Advisory: Limit Low-calorie Sodas and Drinks
3 Aug, 2018 | 04:09h | UTCNews Release: Limit low-calorie sodas and drinks, and stick to water instead, researchers advise (free)
Randomized Trial: Magnesium for the Management of Rapid Atrial Fibrillation
3 Aug, 2018 | 03:59h | UTCLOw dose MAGnesium sulfate versus HIgh dose in the early management of rapid atrial fibrillation: randomised controlled double blind study – Academic Emergency Medicine (link to abstract – $ for full-text)
Commentaries: Low-dose vs. High-dose Magnesium in Rapid Afib – The PharmERToxGuy (free) AND Magnesium to treat rapid Afib in the ED – Univadis (free registration required)
Randomized Trial: Effects of Treating Depression on Outcomes in Patients With Acute Coronary Syndrome
3 Aug, 2018 | 02:59h | UTCEffect of Escitalopram vs Placebo Treatment for Depression on Long-term Cardiac Outcomes in Patients With Acute Coronary Syndrome: A Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
Commentaries: Treating Depression May Improve Cardiac Outcomes, Research Finds – AJMC (free) AND Treating depression may prevent repeat heart attack, study says – UPI (free)
Study: Protease Inhibitors and Cardiovascular Outcomes in Patients With HIV and Heart Failure
3 Aug, 2018 | 02:56h | UTCProtease Inhibitors and Cardiovascular Outcomes in Patients With HIV and Heart Failure – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Commentaries: Protease inhibitors may increase risk of death in people with HIV and heart failure – OnMedica (free) AND Protease inhibitors may increase risk of death in people with HIV and heart failure – Massachusetts General Hospital, via EurekAlert (free)
Review: Timing of Intervention in Aortic Stenosis
26 Jul, 2018 | 20:24h | UTCTiming of intervention in aortic stenosis: a review of current and future strategies – Heart (free)
Opinion: Intensive Blood pressure Control and ‘Dementia’
26 Jul, 2018 | 20:23h | UTCSee also: No, A Big NIH Trial Did Not Show That Lowering Blood Pressure Will Prevent Dementia – Cardiobrief (free)
Guideline: PFO closure vs. Antiplatelet Therapy vs. Anticoagulation for Management of Cryptogenic stroke
26 Jul, 2018 | 18:40h | UTCRapid Recommendations: Patent foramen ovale closure, antiplatelet therapy or anticoagulation therapy alone for management of cryptogenic stroke? A clinical practice guideline – The BMJ (free)
Position Statement: Participation in Leisure Time or Competitive Sports in Athletes-Patients with Coronary Artery Disease
26 Jul, 2018 | 18:22h | UTC
Clinician’s Guide for Trending Cardiovascular Nutrition Controversies
26 Jul, 2018 | 18:21h | UTCRelated – Part I: Trending Cardiovascular Nutrition Controversies – Journal of the American College of Cardiology (free)
Commentary: Chew on This: Review Tackles Controversies in Nutrition for CV Health – TCTMD (free) AND Separating health from hype for a diet that’s kind on your heart – ABC News (free)
Study: Development and Validation of a Cardiovascular Disease Risk-Prediction Model
26 Jul, 2018 | 18:17h | UTCSee also: Heart Attack & Stroke Calculator (free tool)
Commentaries: New health calculator can help predict heart disease risk, estimate heart age – CMAJ, via ScienceDaily (free) AND Calculator can predict heart age, risk for heart disease – UPI (free) AND Algorithm Allows Patients To Calculate Their Risk of Stroke and Heart Disease – MedicalResearch.com (free)
Related Calculators: ACC/AHA CV Risk Calculator (free) AND QRISK3-2017 Cardiovascular Disease Risk Calculator (free)
Consensus Recommendations: The 10 Fundamental Principles of Lay Resuscitation
26 Jul, 2018 | 18:03h | UTC
Opinion: Epinephrine Harms/Helps in Out of Hospital Cardiac Arrest
26 Jul, 2018 | 17:55h | UTCParamedic 2: Epinephrine harms/helps in out of hospital cardiac arrest – First10EM (free)
See Also: Original Article (free study and editorial) AND Expert Reaction (free commentaries)
“Paramedic 2 quick summary:
If 1000 people treated with epinephrine:
– 246 extra ROSC (return of spontaneous circulation)
– 158 extra admissions
– 8 extra survivors (5 with bad neuro outcomes, 3 with good neuro outcomes)
– What those numbers mean is a value question, not a science question.” (via @First10EM see Tweet)
Systematic Review: Blood Pressure Targets in People with Cardiovascular Disease
26 Jul, 2018 | 17:56h | UTCSummary: Blood pressure targets in people with cardiovascular disease – Cochrane Library (free)
“Insufficient evidence to justify lower than standard blood pressure targets in ppl w hypertension + CVD” (via @CochraneHTN see Tweet)
Expert Consensus: Operator and Institutional Recommendations and Requirements for TAVR
26 Jul, 2018 | 17:32h | UTC
Expert Reaction to Trial Looking at Adrenaline for Cardiac Arrests
20 Jul, 2018 | 03:32h | UTCExpert reaction to trial looking at adrenaline for cardiac arrests – Science Media Centre (free)
See original article in yesterday’s issue: A Randomized Trial of Epinephrine in Out-of-Hospital Cardiac Arrest (see #1)
Related Review: The role of adrenaline in cardiopulmonary resuscitation – Critical Care (free)
Systematic Review: To Continue Taking or To Stop Taking Antiplatelet Drugs Before Non-Cardiac Surgery
20 Jul, 2018 | 03:31h | UTCTo continue taking or to stop taking antiplatelet drugs for a few days before non-cardiac surgery in adults – Cochrane Library (link to abstract – $ for full-text)
Summary: To continue taking or to stop taking antiplatelet drugs for a few days before non-cardiac surgery in adults – Cochrane Library (free)
“We found low-certainty evidence that either continuation or discontinuation of antiplatelet therapy before non-cardiac surgery may make little or no difference to mortality, bleeding requiring surgical intervention, or ischaemic events”.
Systematic Review: Omega-6 fats for the Primary and Secondary Prevention of Cardiovascular Disease
20 Jul, 2018 | 03:22h | UTCOmega-6 fats for the primary and secondary prevention of cardiovascular disease – Cochrane Library (link to abstract – $ for full-text)
Summary: Omega-6 fats to prevent and treat heart and circulatory diseases – Cochrane Library (free)
Systematic Review: Polyunsaturated Fatty Acids for the Primary and Secondary Prevention of Cardiovascular Disease
20 Jul, 2018 | 03:22h | UTCPolyunsaturated fatty acids for the primary and secondary prevention of cardiovascular disease – Cochrane Library (link to abstract – $ for full-text)
Summary: Polyunsaturated fatty acids for prevention and treatment of diseases of the heart and circulation – Cochrane Library (free)
Cohort Study: Metformin and Risk of Hypertension
20 Jul, 2018 | 03:20h | UTC“A reduced risk of hypertension is observed in metformin users in a dose‐response pattern”.
Randomized Trial: E-Counseling for Hypertension
20 Jul, 2018 | 03:07h | UTCCommentaries: Virtual counseling helps lower blood pressure – AHA News (free) AND E-counseling can lower blood pressure, heart disease risk – Medical News Today (free)