Heart Failure/Transplantation | Page 3 of 7 | Links Medicus Content Curation & Alerts in Medicine

Summary: The study aimed to assess the effectiveness of opioids in treating breathlessness in patients with heart failure and to evaluate their adverse effects. The authors conducted a systematic review of randomized controlled trials (RCTs) and included eight studies with 271 patients.

The results showed that opioids did not provide significant benefits in managing breathlessness in advanced HF and significantly increased the risk of adverse events such as nausea, vomiting, and constipation.

The authors suggest that opioids should be considered only as a last resort when other interventions have failed or in emergency situations.

Article: Effect of opioids for breathlessness in heart failure: a systematic review and meta-analysis – Heart

#ACC23 – RCT | Five-year follow-up after transcatheter repair of secondary mitral regurgitation

6 Mar, 2023 | 14:28h | UTC

Five-Year Follow-up after Transcatheter Repair of Secondary Mitral Regurgitation – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries:

COAPT at 5 Years: MitraClip Still Ahead, but Deaths and Crossovers Cast Shadows – TCTMD

Minimally Invasive Mitral Valve Repair Reduces Hospitalizations and Deaths – American College of Cardiology

Commentary on Twitter

Transcatheter repair of secondary mitral regurgitation for heart failure was associated with a lower rate of hospitalization for heart failure and lower all-cause mortality than medical therapy at 5 years of follow-up.

Full COAPT trial: https://t.co/rcJ6RQEMAX #ACC23/#WCCardio pic.twitter.com/sM8R50oaBq

— NEJM (@NEJM) March 5, 2023

Guideline | Acute mechanical circulatory support

27 Feb, 2023 | 13:04h | UTC

The International Society for Heart and Lung Transplantation/Heart Failure Society of America Guideline on Acute Mechanical Circulatory Support – The Journal of Heart and Lung Transplantation

Commentary: New guideline on mechanical circulatory support tackles device selection, ethical dilemmas and more – Cardiovascular Business

[Not published yet] M-A | Too little sodium can be harmful to heart failure patients

24 Feb, 2023 | 13:59h | UTC

Summary: New research presented at the American College of Cardiology’s annual scientific session suggests that heart failure patients restricting their dietary sodium intake to levels below the standard recommended maximum of 2.3 grams per day do not have additional benefits and may be at increased risk of death. The study analyzed nine randomized controlled trials that assessed different levels of sodium restriction and found that patients following a diet with a sodium intake target below 2.5 grams per day were 80% more likely to die than those following a diet with a target of 2.5 grams per day or more. The researchers recommend establishing a safe level of sodium consumption instead of overly restricting sodium.

News release: Too Little Sodium Can be Harmful to Heart Failure Patients – American College of Cardiology

Worsening heart failure: nomenclature, epidemiology, and future directions

15 Feb, 2023 | 16:06h | UTC

Worsening Heart Failure: Nomenclature, Epidemiology, and Future Directions: JACC Review Topic of the Week – Journal of the American College of Cardiology

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