Cardiac Critical Care
ESC 0/1-hour algorithm unable to safely exclude 30-day cardiac death or MI in patients with known coronary artery disease, study finds
8 Mar, 2023 | 14:12h | UTCSummary:
The study aimed to determine if the European Society of Cardiology (ESC) 0/1-hour algorithm using high-sensitivity cardiac troponin T (hs-cTnT) could achieve a negative predictive value of 99% or higher for 30-day cardiac death or myocardial infarction (MI) among emergency department patients with chest pain and known coronary artery disease (CAD).
The study included 1430 adults, and the algorithm had a negative predictive value of 96.6% for 30-day cardiac death or MI among patients with known CAD, suggesting that the algorithm may not be able to safely exclude 30-day cardiac death or MI in these patients.
These findings suggest that clinicians should be cautious when using the ESC 0/1-hour hs-cTnT algorithm in patients with known CAD.
Article: Performance of the European Society of Cardiology 0/1-Hour Algorithm With High-Sensitivity Cardiac Troponin T Among Patients With Known Coronary Artery Disease – JAMA Cardiology (link to abstract – $ for full-text)
Related:
Performance of the European Society of Cardiology 0/1-Hour, 0/2-Hour, and 0/3-Hour Algorithms for Rapid Triage of Acute Myocardial Infarction: An International Collaborative Meta-analysis – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentary on Twitter
In this diagnostic study of 1430 adults, the high-sensitivity troponin T (hs-cTnT) ESC 0/1-hour algorithm had a negative predictive value of 96.6% for 30-day cardiac death or MI among patients with known coronary artery disease. https://t.co/FnILIazEnU
— JAMA Cardiology (@JAMACardio) March 1, 2023
M-A | Early vs. delayed coronary angiography after out-of-hospital cardiac arrest without ST-segment elevation
6 Mar, 2023 | 14:12h | UTCSummary:
This systematic review and meta-analysis of randomized controlled trials evaluated the efficacy and safety of early vs. delayed coronary angiography following an out-of-hospital cardiac arrest in patients without ST elevation on the ECG.
The review included six trials with 1,590 patients and found that early angiography probably has no effect on mortality, survival with good neurologic outcomes, and ICU length of stay, indicating that the procedure should not be routinely recommended for these patients.
Related:
Emergency vs Delayed Coronary Angiogram in Survivors of Out-of-Hospital Cardiac Arrest: Results of the Randomized, Multicentric EMERGE Trial – JAMA Cardiology (link to abstract – $ for full-text)
Guideline | Acute mechanical circulatory support
27 Feb, 2023 | 13:04h | UTC
RCT | Rivaroxaban shows promise compared to Enoxaparin in the acute phase of an acute coronary syndrome
16 Feb, 2023 | 15:20h | UTCInvited Commentary: Rivaroxaban for Patients With Acute Coronary Syndromes—Where Do We Stand? – JAMA Network Open
Commentary on Twitter
The H-REPLACE RCT: short-term rivaroxaban (5mg 2x/day) was noninferior to enoxaparin in safety + efficacy during 6-month follow-up among patients with acute coronary syndrome who missed the primary reperfusion window and before selective revascularization. https://t.co/TIHOwGSWjJ
— JAMA Network Open (@JAMANetworkOpen) February 10, 2023
Review | Indications, clinical impact, and complications of critical care transesophageal echocardiography
15 Feb, 2023 | 15:45h | UTC
Retrospective Study | Post-cardiac surgery fungal mediastinitis: clinical features, pathogens and outcome
15 Feb, 2023 | 15:40h | UTCPost-cardiac surgery fungal mediastinitis: clinical features, pathogens and outcome – Critical Care
Review | Liberation from mechanical ventilation in the cardiac intensive care unit
8 Feb, 2023 | 12:45h | UTCLiberation From Mechanical Ventilation in the Cardiac Intensive Care Unit – JACC: Advances
Cohort Study | Predictors of acute coronary occlusion in patients with out-of-hospital cardiac arrest without ST-segment elevation
3 Feb, 2023 | 14:20h | UTCAcute Coronary Occlusion in Patients With Non-ST-Segment Elevation Out-of-Hospital Cardiac Arrest – Journal of the American College of Cardiology (link to abstract – $ for full-text)
JACC Podcast: Acute Coronary Occlusion in Patients with Non-ST-segment Elevation Out-of-hospital Cardiac Arrest
Commentary: Coronary Occlusion in Patients With Non-ST Elevation Cardiac Arrest – American College of Cardiology
Related:
Emergency vs Delayed Coronary Angiogram in Survivors of Out-of-Hospital Cardiac Arrest: Results of the Randomized, Multicentric EMERGE Trial – JAMA Cardiology (link to abstract – $ for full-text)
M-A | Cardiovascular and renal effects of SGLT2 inhibitor initiation in acute heart failure
3 Feb, 2023 | 14:23h | UTC
Transfusion thresholds for acute coronary syndromes — insights from the TRICS‐III trial and meta‐analysis
3 Feb, 2023 | 13:58h | UTC
Deconstructing the dogma: meta-analysis of adjunctive gentamicin and rifampin in staphylococcal prosthetic valve endocarditis
2 Feb, 2023 | 15:00h | UTC
Commentary on Twitter
So excited to share an #IDTwitter collaborative article!
Together with @Cortes_Penfield @DrToddLee @syctong @DrEmilyMcD @JGPharmD and Irani Thevarajan, we did a systematic review & meta-analysis on gent & rifampin in Staph prosthetic valve endocarditis!https://t.co/XocwPvut3x
— Jonathan Ryder, MD (@JonathanRyderMD) October 31, 2022
RCT | Nighttime dexmedetomidine for delirium prevention in non-mechanically ventilated patients after cardiac surgery
1 Feb, 2023 | 12:58h | UTC
RCT | Early extracorporeal CPR did not improve outcomes in patients with refractory out-of-hospital cardiac arrest
30 Jan, 2023 | 01:18h | UTCEarly Extracorporeal CPR for Refractory Out-of-Hospital Cardiac Arrest – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Early Extracorporeal CPR for Out-of-Hospital Cardiac Arrest – American College of Cardiology
Commentary on Twitter
In a randomized trial, patients with out-of-hospital cardiac arrest who received extracorporeal CPR and those who received conventional CPR had similar results for survival and favorable neurologic outcomes. https://t.co/Irw8nrV8AA pic.twitter.com/lOPsBzhP3O
— NEJM (@NEJM) January 27, 2023
Perspective | Is it time to retire the diagnosis “hypertensive emergency”?
27 Jan, 2023 | 12:26h | UTC
M-A | Colchicine for prevention of post-operative atrial fibrillation
27 Jan, 2023 | 12:03h | UTC
Delayed QT prolongation: derivation of a novel risk factor for adverse cardiovascular events from acute drug overdose
26 Jan, 2023 | 12:10h | UTCCommentary: January 2023 Annals of Emergency Medicine Journal Club
Cardiogenic Shock | Emergency department-focused management
25 Jan, 2023 | 11:21h | UTCCardiogenic Shock: Emergency Department-Focused Management – emDocs
Related: The medical treatment of cardiogenic shock – Journal of Intensive Medicine
AHA Statement | Surgical management and mechanical circulatory support in high-risk pulmonary embolisms
24 Jan, 2023 | 14:40h | UTCNews Release: New statement suggests more patients may benefit from surgery for pulmonary embolism – American Heart Association
Commentary from one of the authors on Twitter (thread – click for more)
? New @AHAScience Statement on Surgical Management and Mechanical Circulatory Support in High Risk Acute PE!
Presented today #STS2023 by Writing Chair @GoldbergJBCTMD from @WestchesterMed & published in @CircAHA:https://t.co/YjeA8QbHOw
Endorsed by @STS_CTsurgery @ @AATSHQ pic.twitter.com/OhnRXnriq8
— Jay Giri (@jaygirimd) January 23, 2023
Retrospective Study | Serial troponin-T and long-term outcomes in suspected acute coronary syndrome
24 Jan, 2023 | 14:09h | UTC
Commentary on Twitter
Serial troponin-T and long-term outcomes in suspected acute coronary syndrome https://t.co/cTm1fJTuKl#AHA22 @ehj_ed @rladeiraslopes pic.twitter.com/0p8cO8zhzi
— European Society of Cardiology Journals (@ESC_Journals) November 7, 2022
Review | Wellens syndrome: an important consideration in patients with chest pain
23 Jan, 2023 | 13:26h | UTCWellens syndrome: An important consideration in patients with chest pain – JAAPA
Commentary: Wellens Syndrome Important to Consider if Chest Pain: Key Points – American College of Cardiology
AHA Scientific Statement | Diagnosis, workup, risk reduction of transient ischemic attack in the ED setting
20 Jan, 2023 | 14:56h | UTCNews Release: Stroke symptoms, even if they disappear within an hour, need emergency assessment – American Heart Association
Review | Getting ahead of the game: in-hospital initiation of HFrEF therapies
20 Jan, 2023 | 14:24h | UTC
Development and validation of a risk stratification tool for patients with Type 2 Myocardial Infarction
17 Jan, 2023 | 13:23h | UTCCommentary: Improving Risk Stratification for Patients With Type 2 MI – American College of Cardiology
Commentary on Twitter
T2-risk score was developed and validated to prognosticate outcomes (subsequent MI and death from any cause or death from CVD at 1 year) using clinical variables among patients w/ Type 2 MI. Get the study details: https://t.co/OqFdYj9bW6 #HeartFailure
— American College of Cardiology (@ACCinTouch) January 13, 2023
Nonconvulsive status epilepticus following cardiac arrest: overlooked, untreated and misjudged
12 Jan, 2023 | 12:43h | UTC
Ten rules for optimizing ventilatory settings and targets in post-cardiac arrest patients
11 Jan, 2023 | 14:13h | UTC