Allergy & Immunology
EULAR/ACR points to consider for diagnosis, management and monitoring of the interleukin-1 mediated autoinflammatory diseases.
24 Jun, 2022 | 11:23h | UTC
M-A: Reproducibility of food challenge to cow’s milk.
15 Jun, 2022 | 10:42h | UTC
Position Paper: Diagnostic therapeutic care pathway for pediatric food allergies and intolerances.
14 Jun, 2022 | 11:05h | UTC
Host-directed immunotherapy of viral and bacterial infections: past, present and future.
13 Jun, 2022 | 07:41h | UTCHost-directed immunotherapy of viral and bacterial infections: past, present and future – Nature Reviews Immunology (if the link is paywalled, try this one in PMC)
Commentary on Twitter
A Perspective in @NatRevImmunol reflects on the historical development of host-directed immunotherapeutic interventions for infections and how historical insights can be used in the therapy of SARS-CoV-2 and Mycobacterium tuberculosis infections. https://t.co/5WOXzePpFS pic.twitter.com/dpj1XNi2me
— Nature Portfolio (@NaturePortfolio) June 11, 2022
Another study suggests the Omicron variant is associated with a reduced risk of Multisystem Inflammatory Syndrome in Children compared to previous SARS-CoV-2 variants.
10 Jun, 2022 | 12:38h | UTCRelated study: Severity and Incidence of Multisystem Inflammatory Syndrome in Children During 3 SARS-CoV-2 Pandemic Waves in Israel – JAMA AND Commentary: Kids’ COVID syndrome—MIS-C—less severe in Omicron – CIDRAP
Commentary on Twitter
Study found that the risk of multisystem inflammatory syndrome in children (MIS-C) following SARS-CoV-2 infection during the #Omicron wave substantially lower compared to previous #SARSCoV2 variants. https://t.co/GYrz9XA72Z
— JAMA Pediatrics (@JAMAPediatrics) June 8, 2022
Drug-related hypersensitivity reactions leading to emergency department: original data and systematic review.
10 Jun, 2022 | 10:46h | UTC
M-A: Oral Janus kinase inhibitors in the treatment of atopic dermatitis.
3 Jun, 2022 | 10:49h | UTCCommentary: Systematic Review Suggests Oral JAK Inhibitors Effective in AD – HCP Live
Consensus on the diagnosis and treatment of cow’s milk protein allergy.
2 Jun, 2022 | 10:56h | UTC
Cohort Study: Risk of hematologic cancer in patients with undifferentiated pruritus.
30 May, 2022 | 10:35h | UTCRisk of Hematologic Cancer in Patients With Undifferentiated Pruritus – JAMA Dermatology (link to abstract – $ for full-text)
Commentary: Undifferentiated Pruritus Associated with Increased Risk of Hematologic Cancer – HCP Live
Cohort Study: Most egg allergy and nearly one-third of peanut allergy resolves naturally by age 6 years.
27 May, 2022 | 11:46h | UTCThe natural history of peanut and egg allergy in children up to age 6 years in the HealthNuts population-based longitudinal study – The Journal of Allergy & Clinical Immunology (link to abstract – $ for full-text)
Joint consensus guidelines on the diagnosis and management of eosinophilic esophagitis in children and adults.
25 May, 2022 | 11:32h | UTC
Cohort Study: Analysis of neuropsychiatric diagnoses after montelukast initiation.
25 May, 2022 | 11:05h | UTCAnalysis of Neuropsychiatric Diagnoses After Montelukast Initiation – JAMA Network Open
Related:
Adverse drug reactions of montelukast in children and adults – Pharmacology Research & Perspectives
Commentary on Twitter
This cohort study of patients with asthma or allergic rhinitis found montelukast use is associated with higher odds of neuropsychiatric outcomes, including anxiety and insomnia. https://t.co/HAzcADsHZc
— JAMA Network Open (@JAMANetworkOpen) May 24, 2022
Review: Allergic asthma is a risk factor for human cardiovascular diseases.
23 May, 2022 | 00:48h | UTCAllergic asthma is a risk factor for human cardiovascular diseases – Nature Cardiovascular Research
Commentary on Twitter
A Review in @NatureCVR discusses how asthma and allied allergic conditions may contribute to the prevalence, incidence and progression of cardiovascular diseases and vice versa. https://t.co/6kRj9LvOfa pic.twitter.com/Ydq8X2k1rY
— Nature Portfolio (@NaturePortfolio) May 18, 2022
Review: Unexplained post-acute infection syndromes.
19 May, 2022 | 10:58h | UTCUnexplained post-acute infection syndromes – Nature Medicine (if the link is paywalled, try this one)
Commentary on Twitter
A @NatureMedicine tour de force review of the unexplained post-acute infectious syndromes, which includes #LongCovid and many others https://t.co/5RnyY9l0eQ
by @jan_choutka @mhornig @VirusesImmunity pic.twitter.com/dhYeZYnM1U— Eric Topol (@EricTopol) May 18, 2022
Antibiotics given shortly before cesarean birth not linked to asthma and eczema in young children.
19 May, 2022 | 10:46h | UTCNews Release: Antibiotics given shortly before cesarean birth not linked to asthma and eczema in young children – University of Birmingham
Review | Disorders of ubiquitylation: unchained inflammation.
18 May, 2022 | 10:36h | UTCDisorders of ubiquitylation: unchained inflammation – Nature Reviews Rheumatology (if the link is paywalled, try this one in PMC)
Commentary on Twitter
New content online! Disorders of ubiquitylation: unchained inflammation https://t.co/L8dbPDcA6T pic.twitter.com/LlbRreOQzc
— NatRevRheumatol (@NatRevRheumatol) May 6, 2022
New versions of Omicron are masters of immune evasion.
13 May, 2022 | 11:37h | UTCNew versions of Omicron are masters of immune evasion – Science
Commentary on Twitter
"Based on its immunological profile, it [Omicron & its subvariants] should be called SARS-3"https://t.co/zxV3T2SKIB@gretchenvogel @NewsfromScience
w/ @K_G_Andersen @Tuliodna @linfa_wang pic.twitter.com/ToKDqNGH74— Eric Topol (@EricTopol) May 12, 2022
Guideline: Contact dermatitis.
10 May, 2022 | 10:54h | UTCGerman S1 guideline: Contact dermatitis – Journal of the German Society of Dermatology
Translating research into practice: What’s new in the 2021 EAACI food allergy prevention guidelines?
8 Apr, 2022 | 10:00h | UTCOriginal Guideline: EAACI guideline: Preventing the development of food allergy in infants and young children – Pediatric Allergy and Immunology
Related:
Study: Early Introduction of Allergenic Foods Can Prevent Food Allergies in High Risk Infants
AAP Updated Recommendations for Dietary Interventions to Prevent Atopic Disease
Timing of introduction of allergenic solids for infants at high risk – Canadian Paediatric Society (free)
Short Review: Food Allergy Prevention with Early Food Introduction
Review: Predicting the course of asthma from childhood until early adulthood.
1 Apr, 2022 | 08:32h | UTC
[Preprint] Retrospective cohort study: second booster vaccine and Covid-19 mortality in adults 60 to 100 years old.
30 Mar, 2022 | 10:44h | UTCSecond Booster Vaccine and Covid-19 Mortality in Adults 60 to 100 Years Old – Research Square
Commentaries:
Huge Study Finds Second COVID-19 Booster is ‘Life-saving’ for Over 60s – Health Policy Watch
Fourth COVID-19 vaccine dose substantially reduces mortality in the elderly – News Medical
U.S. approves second Covid-19 booster for people 50 and older and immunocompromised individuals.
30 Mar, 2022 | 10:42h | UTCU.S. approves second Covid-19 booster for people 50 and older – STAT
FDA OKs second COVID booster shot for older Americans – CIDRAP
Retrospective Cohort Study: Risks for anaphylaxis with intravenous iron formulations.
30 Mar, 2022 | 10:16h | UTCRisks for Anaphylaxis With Intravenous Iron Formulations: A Retrospective Cohort Study – Annals of Internal Medicine (link to abstract – $ for full-text)
News Release: Risk of Severe Allergic Reaction Higher with Two Intravenous Iron-Boosting Products – Rutgers University
Commentary: Risks for Anaphylaxis Compared Among IV Iron Products – HealthDay
Cohort Study: Prenatal occupational disinfectant exposure linked to increased risk of childhood allergies.
30 Mar, 2022 | 08:48h | UTCCommentary: Disinfectant use by pregnant women may increase risk for asthma and eczema in children – BMJ/News Medical
Commentary on Twitter
Disinfectant use during pregnancy linked to childhood asthma and eczema, suggests @OEM_BMJ research https://t.co/90JYoTFHpo pic.twitter.com/zlqouZWQSM
— BMJ (@bmj_company) March 29, 2022
The prevalence of penicillin allergy labeling ranged from 0.9% to 10.2% across practices in a large pediatric cohort, raising questions regarding the validity of those labels and the unnecessary use of second-line antibiotics that may follow.
28 Mar, 2022 | 09:48h | UTCM-A: Most patients with allergy to Penicillin can be given Cefazolin
Podcast: A Clinical Pharmacologist’s Perspective on Penicillin Allergy
Study: Development and Validation of a Penicillin Allergy Clinical Decision Rule
Consensus Recommendations: Management of a Surgical Patient with a Label of Penicillin Allergy
Practical Guide for Pharmacists to Successfully Implement Penicillin Allergy Skin Testing
NICE: Double Check Patients with ‘Penicillin Allergy’ to Avoid Increased MRSA Risk
Commentary on Twitter
In this cohort study of more than 330,000 children, less than 5% were labeled with penicillin allergy with wide variation across practices, with 8% of those labeled despite not receiving any penicillin prescription. https://t.co/kvXcm1RKRd
— JAMA Network Open (@JAMANetworkOpen) March 15, 2022