Allergy & Immunology
SARS-CoV-2 immunity: Review and applications to phase 3 vaccine candidates
22 Oct, 2020 | 09:36h | UTCSARS-CoV-2 immunity: review and applications to phase 3 vaccine candidates – The Lancet
Commentary: The COVID-19 vaccine pipeline – News Medical
Commentary on Twitter
NEW Review—G Poland, I Ovsyannikova & R Kennedy @MayoClinic discuss what is currently known about human humoral & cellular immune responses to SARS-CoV-2 & relate this knowledge to the #COVID19 vaccines currently in phase 3 clinical trials https://t.co/eDkFq4WStA pic.twitter.com/hfw6yjviym
— The Lancet (@TheLancet) October 14, 2020
Perspective: Immunity and Re-Infection
22 Oct, 2020 | 09:34h | UTCImmunity and Re-Infection – Science Translational Medicine
‘Super antigens’ tied to mysterious COVID-19 syndrome in children
21 Oct, 2020 | 09:21h | UTC‘Super antigens’ tied to mysterious COVID-19 syndrome in children – National Geographic
Answering key questions about COVID-19 vaccines
18 Oct, 2020 | 23:10h | UTCAnswering Key Questions About COVID-19 Vaccines – JAMA
Commentary on Twitter
Many individuals are hesitant about receiving #COVID19 vaccines. It is critical that clinicians stay well informed about emerging data so that they can help patients make sound decisions https://t.co/1QDwOKuDqc @JesseGoodmanMD @ImmunizeOrg @pharmacists
— JAMA (@JAMA_current) October 16, 2020
Review: Why and how vaccines work
16 Oct, 2020 | 09:32h | UTCWhy and How Vaccines Work – Cell
Commentary on Twitter
Why and how vaccines work, including how the covid-19 vaccines are positioned, new adjuvants
New @CellCellPress by @VirusesImmunity and @SaadOmer3 https://t.co/ydGfLJh0Uv pic.twitter.com/8niIaMVlAQ— Eric Topol (@EricTopol) October 15, 2020
Pediatric inflammatory multisystem syndrome temporally-associated with SARS-CoV-2 infection: An overview
15 Oct, 2020 | 09:21h | UTC
Coronavirus vaccine: What we know so far – a comprehensive guide by academic experts
15 Oct, 2020 | 09:17h | UTC
Podcast: Ten things every new doctor should know about drug reactions
15 Oct, 2020 | 09:02h | UTCTen Things Every New Doctor Should Know About Drug Reactions – JAMA
Genomic evidence for reinfection with SARS-CoV-2: A case study
14 Oct, 2020 | 09:39h | UTCGenomic evidence for reinfection with SARS-CoV-2: a case study – The Lancet Infectious Diseases
Commentaries: First Case Of COVID-19 Reinfection In The US Confirmed; Exposure to Virus May Not Guarantee Protective Immunity, Says New Lancet Study – Health Policy Watch AND What reinfections mean for COVID-19 – The Lancet Infectious Diseases AND You can get reinfected with Covid-19 but still have immunity. Let’s explain. – Vox AND A 25-Year-Old Nevada Man Got COVID-19 Twice. Here’s What We Know—and Don’t Know—About Reinfection – TIME
Related: Dutch woman dies after catching Covid-19 twice, the first reported reinfection death – CNN
Johnson & Johnson Covid-19 vaccine study paused due to unexplained illness in participant
14 Oct, 2020 | 09:31h | UTCJohnson & Johnson Covid-19 vaccine study paused due to unexplained illness in participant – STAT
News Release: Johnson & Johnson Temporarily Pauses All Dosing in Our Janssen COVID-19 Vaccine Candidate Clinical Trials
Commentaries: Johnson & Johnson ‘Pauses’ COVID-19 Vaccine Trial Due To Unexplained Illness In Participant; Eli Lilly Reportedly Suspending Trial Of Antibody Treatment – Health Policy Watch AND Johnson & Johnson pauses Covid-19 vaccine trial after ‘unexplained illness’ – CNN
Non-respiratory presentations of COVID-19, a clinical review
14 Oct, 2020 | 09:33h | UTC
Monoclonal antibody trial halted for safety concern
14 Oct, 2020 | 09:30h | UTCMonoclonal Antibody Trial Halted for Safety Concern – Brief19
[Abstract Only] Randomized trials: Efficacy and safety of a plant-derived influenza vaccine in adults
14 Oct, 2020 | 09:23h | UTCEfficacy, immunogenicity, and safety of a plant-derived, quadrivalent, virus-like particle influenza vaccine in adults (18–64 years) and older adults (≥65 years): two multicentre, randomised phase 3 trials – The Lancet (link to abstract – $ for full-text)
Commentary on Twitter
NEW—First large-scale studies of plant-derived, quadrivalent, virus-like particle influenza vaccine show substantial protection against respiratory illness & influenza-like illness caused by influenza viruses in adults: two randomised phase 3 trials https://t.co/oQbs2uJTXY pic.twitter.com/C6b6Qi6qZ7
— The Lancet (@TheLancet) October 13, 2020
[News release – not published yet] Eli Lilly says its monoclonal antibody cocktail is effective in treating Covid-19
9 Oct, 2020 | 09:09h | UTCEli Lilly says its monoclonal antibody cocktail is effective in treating Covid-19 – STAT
5 things to know about a COVID vaccine: It won’t be a ‘magic wand’
8 Oct, 2020 | 09:05h | UTC5 Things to Know About a COVID Vaccine: It Won’t Be a ‘Magic Wand’ – Kaiser Health News
How the leading coronavirus vaccines work
8 Oct, 2020 | 09:06h | UTCHow the leading coronavirus vaccines work – The Conversation
Related: SARS-CoV-2 Vaccine Development: Current Status – Mayo Clinic Proceedings
Long-term health consequences of COVID-19
6 Oct, 2020 | 00:58h | UTCLong-term Health Consequences of COVID-19 – JAMA
Commentary on Twitter
Persistent post-COVID symptoms could be the from direct tissue invasion by the virus, profound inflammation & cytokine storm, related immune system damage, hypercoagulable state, or some combination https://t.co/G8tI9U3TaL @CarlosdelRio7 lfcollins_md @PreetiNMalani
— JAMA (@JAMA_current) October 5, 2020
Systematic review: Sublingual immunotherapy for asthma
6 Oct, 2020 | 00:11h | UTCSublingual immunotherapy for asthma – Cochrane Library
Summary: Sublingual immunotherapy for asthma – Cochrane Library
Case series of multisystem inflammatory syndrome in adults associated with SARS-CoV-2 infection
4 Oct, 2020 | 23:36h | UTCCommentary: Mysterious inflammatory syndrome tied to COVID-19 strikes adults as well as kids – Live Science
Commentary on Twitter
A new @CDCMMWR finds that adults who had #COVID19 can develop a condition similar to multisystem inflammatory syndrome in children and have severe outcomes including requiring intensive care. Learn more: https://t.co/dU1tS85Sj3. pic.twitter.com/RitCzJsLTL
— CDC (@CDCgov) October 2, 2020
Systemic treatments for eczema: A network meta‐analysis
4 Oct, 2020 | 22:45h | UTCSystemic treatments for eczema: a network meta‐analysis – Cochrane Library
What does it mean if a vaccine is ‘successful’?
2 Oct, 2020 | 09:25h | UTCWhat Does It Mean If a Vaccine Is ‘Successful’? – Wired
‘Provocative results’ boost hopes of antibody treatment for COVID-19
2 Oct, 2020 | 09:21h | UTC‘Provocative results’ boost hopes of antibody treatment for COVID-19 – Science
Proposed clinical criteria for COVID-19-associated hyperinflammatory syndrome
30 Sep, 2020 | 09:50h | UTC
Commentary on Twitter
Defining and grading the clinical hyperinflammatory syndrome with #COVID19 and how this cytokine storm relates to outcomes https://t.co/6Ngp3OHZJx @TheLancetRheum @Intermountain pic.twitter.com/bDGwKpjOI4
— Eric Topol (@EricTopol) September 29, 2020
Investigational COVID-19 vaccine well-tolerated and generates immune response in older adults
30 Sep, 2020 | 09:36h | UTCOriginal Article: Safety and Immunogenicity of SARS-CoV-2 mRNA-1273 Vaccine in Older Adults – New England Journal of Medicine
Commentary on Twitter
The Moderna mRNA vaccine, which elicited antibodies and T cells specific for the Covid-19 virus in adults 55 years of age or younger, elicited similarly high levels of neutralizing-antibody and CD4 T-cell responses in older adults. #COVID19 #SARSCoV2
— NEJM (@NEJM) September 29, 2020
Less than 10% of US population has COVID-19 antibodies, data show
29 Sep, 2020 | 10:12h | UTCLess than 10% of US population has COVID-19 antibodies, data show – CIDRAP
Original Study: Prevalence of SARS-CoV-2 antibodies in a large nationwide sample of patients on dialysis in the USA: a cross-sectional study – The Lancet
Commentary on Twitter
NEW Research—Nationwide cross-sectional analysis of US patients receiving dialysis finds fewer than 10% of people had #COVID19 antibodies by July 2020, and fewer than 10% of those with antibodies had been diagnosed by antigen or PCR testing https://t.co/QWPMO0gCr3 pic.twitter.com/v2K66uLLID
— The Lancet (@TheLancet) September 26, 2020