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Perspective: Why All Randomized Controlled Trials Produce Biased Results

29 May, 2018 | 17:48h | UTC

Why all randomised controlled trials produce biased results – Annals of Medicine (free)

 


Meta-Analysis: Pharmacological Therapies for the Treatment of Opioid-induced Constipation

29 May, 2018 | 17:50h | UTC

Efficacy of pharmacological therapies for the treatment of opioid-induced constipation: systematic review and network meta-analysis – Gut (link to abstract – $ for full-text)

Commentary: Naloxone, naldemedine appear best for opioid-induced constipation after laxatives – ACP Gastroenterology (free)

 


Perspective: Nine Pitfalls of Research Misconduct

29 May, 2018 | 17:48h | UTC

Nine pitfalls of research misconduct – Nature News (free)

 


Research: New Type of Vertigo Identified

29 May, 2018 | 17:40h | UTC

Recurrent spontaneous vertigo with interictal headshaking nystagmus – Neurology (link to abstract – $ for full-text)

Commentaries: New Type of Vertigo Identified – American Academy of Neurology (free) AND Neurologists Identify New Type of Vertigo – MPR (free) AND New Type of Treatable Vertigo Identified – Medscape (free registration required) AND New Type of Spontaneous Vertigo Identified in Korea – MedPage Today (free registration required)

 


IDSA & AASLD Hepatitis C Guidance Updates

28 May, 2018 | 12:56h | UTC

HCV Guidance: Recommendations for Testing, Managing, and Treating Hepatitis C – American Association for the Study of Liver Diseases (AASLD) and the Infectious Diseases Society of America (IDSA) (free)

News Release: HCV Guidance Updates Recommendations for Screening and Treating Key Populations (free)

Related Guideline: EASL Recommendations on Treatment of Hepatitis C 2018 – Journal of Hepatology (free)

 


Perspective: Reimagining the Future of Electronic Health Records

28 May, 2018 | 13:40h | UTC

Subscribing to Your Patients — Reimagining the Future of Electronic Health Records – New England Journal of Medicine (free)

 


Editorial: A1C Targets Should Be Personalized to Maximize Benefits While Limiting Risks

28 May, 2018 | 12:54h | UTC

A1C Targets Should Be Personalized to Maximize Benefits While Limiting Risks – Diabetes Care (free) (via @Abraham_RMI)

Related guideline: Hemoglobin A1c Targets for Glycemic Control With Pharmacologic Therapy for Nonpregnant Adults With Type 2 Diabetes Mellitus: A Guidance Statement Update From the American College of Physicians (free)

“Clinicians should aim to achieve an HbA1c level between 7% and 8% in most patients with type 2 diabetes” (from ACP Guideline, prompting the Editorial)

 


Review: Principles of Fluid Management and Stewardship in Septic Shock

28 May, 2018 | 12:50h | UTC

Principles of fluid management and stewardship in septic shock: it is time to consider the four D’s and the four phases of fluid therapy – Annals of Intensive Care (free) (via @Fluid_Academy)

Related Review: Expert statement for the management of hypovolemia in sepsis – Intensive Care Medicine (free)

 


Latest Developments on the Ebola Outbreak in DRC

28 May, 2018 | 12:52h | UTC

Vaccinations set to begin in Ebola outbreak epicenter – STAT (free) AND Research during Ebola vaccine trial: It’s complicated – Science (free) AND New Ebola Tactics Raise Hope but May Sow Confusion – The New York Times (10 articles per month are free) AND Ebola outbreak in DRC on ‘epidemiological knife-edge,’ says WHO official – Devex (free) AND The success of the new Ebola vaccine will hinge on trust – VOX (free)

 


Perspective: QALYs in 2018—Advantages and Concerns

28 May, 2018 | 12:48h | UTC

QALYs in 2018—Advantages and Concerns – JAMA (free for a limited period)

 


AHA Scientific Statement: Epidemiology, Risk Factors, and Treatments for CVD in South Asians in the U.S.

28 May, 2018 | 12:46h | UTC

Atherosclerotic Cardiovascular Disease in South Asians in the United States: Epidemiology, Risk Factors, and Treatments: A Scientific Statement From the American Heart Association (free PDF)

Commentary: Appreciating Cardiovascular Disease Risk in South Asians: The Time is Now (free)

Top Ten Things to Know: Atherosclerotic Cardiovascular Disease in South Asians in the United States: Epidemiology, Risk Factors, and Treatments (free PDF)

AHA News: South Asians’ high risk of cardiovascular disease has been hidden by a lack of data (free)

News Release: South Asian Americans are at high risk for heart disease and stroke (free)

 


Cohort Study: Vascular Risk Interacts with β-Amyloid Burden in the Progression of Cognitive Decline

28 May, 2018 | 12:44h | UTC

Interactive Associations of Vascular Risk and β-Amyloid Burden With Cognitive Decline in Clinically Normal Elderly Individuals: Findings From the Harvard Aging Brain Study – JAMA Neurology (free for a limited period)

Commentaries: Vascular risk interacts with amyloid levels to increase age-related cognitive decline – Massachusetts General Hospital, via ScienceDaily (free) AND Bad Synergy—Together, Vascular Problems and Aβ Hasten Memory Slippage – AlzForum (free) AND Combo of vascular risk, brain amyloid could quicken mental decline – Cardiovascular Business (free)

 


Cohort Study: Weight Gain with Antidepressant Utilization

28 May, 2018 | 12:38h | UTC

Antidepressant utilisation and incidence of weight gain during 10 years’ follow-up: population based cohort study – The BMJ (free)

Editorial: Antidepressant induced weight gain (free)

Commentaries: Antidepressant therapy and risk of weight gain – The BMJ Opinion (free) AND Taking antidepressants could be linked to weight gain, according to a new study — and some drugs heighten the risk more than others – Business Insider (free) AND Antidepressants linked to risk of weight gain, study shows – OnMedica (free) AND Antidepressant use linked with weight gain – NHS Choices (free)

 


ACOG Committee Opinion: Gynecologic Care for Adolescents and Young Women With Eating Disorders

28 May, 2018 | 12:34h | UTC

Committee Opinion: Gynecologic Care for Adolescents and Young Women With Eating Disorders – American College of Obstetricians and Gynecologists (free)

News Release: Ob-Gyns Have Important Role on Care Team for Women with Eating Disorders – ACOG (free)

Commentary: OB/GYN Group Offers Advice on Caring for Teens, Young Women with Eating Disorders – Physician’s First Watch (free)

 


Randomized Trial: Low-fat Diet Associated with Better Outcomes in Breast Cancer

28 May, 2018 | 12:42h | UTC

Association of Low-Fat Dietary Pattern With Breast Cancer Overall Survival: A Secondary Analysis of the Women’s Health Initiative Randomized Clinical Trial – JAMA Oncology (free)

Commentaries: Low-fat Diet May Improve Overall Survival in Newly Diagnosed Breast Cancer – Oncology Nurse Advisor (free) AND Low-fat diet reduces risk of breast cancer death – NHS Choices (free)

 


Perspective: Ten Years of the Surgical Safety Checklist

28 May, 2018 | 12:30h | UTC

Ten years of the Surgical Safety Checklist – British Journal of Surgery (free)

 


Systematic Review: Burden of Allergic Rhinitis and Allergic Rhinoconjunctivitis on Adolescents

28 May, 2018 | 12:32h | UTC

The burden of allergic rhinitis and allergic rhinoconjunctivitis on adolescents: a literature review – Annals of Allergy, Asthma and Immunology (free)

Commentary: Impact of Allergic Rhinitis, Rhinoconjunctivitis on Adolescents “Far-Reaching” – MPR (free)

 


Cohort Study: The Role of Job Strain in the Onset of Mental Disorders

28 May, 2018 | 12:24h | UTC

The role of job strain in understanding midlife common mental disorder: a national birth cohort study – The Lancet Psychiatry (link to abstract – $ for full-text)

Commentaries: How job strain may impair mental health – Medical News Today (free) AND Job strain linked to onset of common mental illness – Black Dog Institute, via MedicalXpress (free) AND Job Stress May Be a ‘Substantial Contributor’ to Mental Illness – Medscape (free registration required)

 


Systematic Analysis: Measuring Performance on the Healthcare Access and Quality Index Worldwide

28 May, 2018 | 12:19h | UTC

Measuring performance on the Healthcare Access and Quality Index for 195 countries and territories and selected subnational locations: a systematic analysis from the Global Burden of Disease Study 2016 – The Lancet (free)

Invited Commentary: Going further to measure improvements in health-care access and quality (free)

 


Perspective: Can Genetic Counselors Keep Up With 23andMe?

28 May, 2018 | 12:29h | UTC

Can Genetic Counselors Keep Up With 23andMe? – The Atlantic (free)

 


Pre-Post Intervention Study: Decreased Surgical Site Infection Rate in Hysterectomy

28 May, 2018 | 12:21h | UTC

Decreased Surgical Site Infection Rate in Hysterectomy: Effect of a Gynecology-Specific Bundle – Obstetrics & Gynecology (link to abstract – $ for full-text)

Commentaries: Surgical site infection rate can be reduced in hysterectomy – MedicalXpress (free) AND Prevention Bundle Halves Rate of Surgical Site Infections, Study Suggests – Medscape (free registration required)

 


Cohort Study: Pre-pregnancy Maternal BMI and Optimal Weight Gain During Pregnancy

28 May, 2018 | 12:17h | UTC

Relationship between pre-pregnancy maternal BMI and optimal weight gain in singleton pregnancies – Heliyon (free)

Commentaries: Very obese women should lose weight during pregnancy for a healthy baby – Elsevier, via ScienceDaily (free) AND Very Obese Women: Lose Weight in Pregnancy for Healthy Baby – Medscape (free registration required)

 


Pragmatic Trial: E-Cigarettes, Incentives, and Drugs for Smoking Cessation

24 May, 2018 | 23:42h | UTC

A Pragmatic Trial of E-Cigarettes, Incentives, and Drugs for Smoking Cessation – New England Journal of Medicine (free)

Commentaries: Money a better motivator to stop smoking than free e-cigs or quit aids – Reuters (free) AND E-cigarettes aren’t better at helping smokers quit than other strategies – Journalist’s Resource (free) AND For Smoking Cessation, Money Whispers Louder than Nicotine Replacement – MedPage Today (free registration required)

“Trial finds financial incentives most effective – but nothing very effective” (from MedPage Today)

 


Randomized Trials: Renal Denervation to Treat Hypertension

24 May, 2018 | 23:40h | UTC

Endovascular ultrasound renal denervation to treat hypertension (RADIANCE-HTN SOLO): a multicentre, international, single-blind, randomised, sham-controlled trial – The Lancet (link to abstract – $ for full-text)

Related Article: Effect of renal denervation on blood pressure in the presence of antihypertensive drugs: 6-month efficacy and safety results from the SPYRAL HTN-ON MED proof-of-concept randomised trial (free)

Commentaries: Two Sham-Controlled Renal Denervation Studies Offer Hope in Hypertension – TCTMD (free) AND Renal denervation linked to significant drops in blood pressure – Cardiovascular Business (free) AND Novel Renal Denervation Catheters Showing Modest BP Reductions – MedPage Today (free registration required)

 


Review: Management of Complications Associated with Intravascular Devices in the Critically Ill

24 May, 2018 | 23:41h | UTC

A state of the art review on optimal practices to prevent, recognize, and manage complications associated with intravascular devices in the critically ill – Critical Care Medicine (free for a limited period)

Source: Critical Care Reviews Newsletter

 


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