All Posts
Case Report: Patient with Breast Cancer Treated by T cell Immunotherapy
18 Jun, 2018 | 12:53h | UTCImmune recognition of somatic mutations leading to complete durable regression in metastatic breast cancer – Nature Medicine (free for a limited period)
Commentaries: New approach to immunotherapy leads to complete response in breast cancer patient unresponsive to other treatments – eCancer News (free) AND Therapy Made From Patient’s Immune System Shows Promise For Advanced Breast Cancer – NPR (free) AND Expert reaction to paper reporting a case of breast cancer being treated by T cell immunotherapy, published in Nature Medicine – NPR (free)
NCCN Guideline: Neuroendocrine and Adrenal Tumors
18 Jun, 2018 | 15:37h | UTCNCCN Guidelines Insights: Neuroendocrine and Adrenal Tumors, Version 2.2018 (free)
Guideline: Conservative Treatment on Lower Limb Muscle Injuries in Athlete
18 Jun, 2018 | 14:05h | UTC
Meta-Analysis: Effectiveness of Medical Treatment for Cushing’s Syndrome
18 Jun, 2018 | 13:44h | UTCCommentary: Medical therapy ‘reasonable option’ vs. surgery in Cushing’s disease – Healio (free registration required)
Randomized Trial: Impact of Intensive Care Management on High-Risk Patients’ Costs and Utilization
18 Jun, 2018 | 11:23h | UTCImpact of Primary Care Intensive Management on High-Risk Veterans’ Costs and Utilization: A Randomized Quality Improvement Trial – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Intensive care management for high-risk VA patients didn’t affect overall costs – ACP Hospitalist (free) AND Intensive management for sicker patients increases outpatient care but not costs – 2 Minute Medicine (free)
Cross-Sectional Study: Water Fluoridation and Dental Caries in Children and Adolescents
18 Jun, 2018 | 11:10h | UTCWater Fluoridation and Dental Caries in U.S. Children and Adolescents – Journal of Dental Research (link to abstract – $ for full-text)
Commentaries: Study: Better fluoridated water access leads to less tooth decay – UPI (free) AND Water fluoridation confirmed to prevent dental decay in US children and adolescents – International & American Associations for Dental Research, via ScienceDaily (free)
Report: Current Endovascular Strategies for Cerebral Venous Thrombosis
18 Jun, 2018 | 09:15h | UTC
Meta-Analysis: Effects of Restrictive Red Blood Cell Transfusion on the Prognoses of Adult Patients Undergoing Cardiac Surgery
18 Jun, 2018 | 06:32h | UTC
Randomized Trial: Duloxetine in Patients with Knee Osteoarthritis
18 Jun, 2018 | 10:08h | UTC
Randomized Trial: Ethanol Lock Therapy Not Effective for Central Line-associated Bloodstream Infection in Pediatric Cancer
18 Jun, 2018 | 08:34h | UTCTreatment and secondary prophylaxis with ethanol lock therapy for central line-associated bloodstream infection in paediatric cancer: a randomised, double-blind, controlled trial – The Lancet Infectious Diseases (link to abstract – $ for full-text)
Commentaries: Rigorous study finds widely used treatment for infection fails young cancer patients – eCancer News (free) AND Study: Catheter infection treatment ineffective for young cancer patients – UPI (free)
Guideline: Molecular Testing for Colorectal Cancer Treatment
18 Jun, 2018 | 05:50h | UTC
Cohort Study: Screening Men for Abdominal Aortic Aneurysm Questioned
18 Jun, 2018 | 00:25h | UTCBenefits and harms of screening men for abdominal aortic aneurysm in Sweden: a registry-based cohort study – The Lancet (free to abstract – $ for full-text)
Commentaries: Screening Programs for Abdominal Aortic Aneurysm Need a Rethink, Swedish Study Contends – TCTMD (free) AND Screening for aortic aneurysms in older men questioned – University of Gothemburg, via EurekAlert (free) AND Screening for Abdominal Aortic Aneurysm Questioned – NEJM Physician’s First Watch (free) AND Routine Aortic Aneurysm Screening Questioned – MedPage Today (free registration required)
Expert Analysis: Acute Coronary Syndrome Management in a Patient in Need of Noncardiac Surgery
18 Jun, 2018 | 00:23h | UTCACS Management in a Patient in Need of Noncardiac Surgery – American College of Cardiology (free)
BTS Guideline: Outpatient Management of Pulmonary Embolism
18 Jun, 2018 | 00:26h | UTC
Randomized Trial: Fluid Infusion Rates for Pediatric Diabetic Ketoacidosis
18 Jun, 2018 | 00:24h | UTCClinical Trial of Fluid Infusion Rates for Pediatric Diabetic Ketoacidosis – New England Journal of Medicine (link to abstract – $ for full-text)
Quick Take Video Summary: Does Infusion Rate Affect Neurologic Outcomes in Pediatric DKA? (free)
Commentaries: PEM Practice Changing Paper: Clinical Trial of Fluid Infusion Rates for Pediatric DKA – Aliem (free) AND The Rate of Resuscitation in Pediatric DKA – Emergency Medicine Literature of Note (free) AND Infusion Type Doesn’t Affect Brain Outcomes in Pediatric DKA – Medscape (free)
Randomized Trial: Coronary CT Angiography vs Stress Echocardiography in Acute Chest Pain
18 Jun, 2018 | 00:22h | UTCCoronary Computed Tomography Angiography Versus Stress Echocardiography in Acute Chest Pain: A Randomized Controlled Trial – JACC: Cardiovascular Imaging (link to abstract – $ for full-text)
Commentary: The Patient Presenting With Chest Pain: Stress Echo Gives Coronary CTA a Run for Its Money – TCTMD (free)
Guideline: Efficacy and Tolerability of the New Antiepileptic Drugs
18 Jun, 2018 | 00:21h | UTCPractice guideline update summary: Efficacy and tolerability of the new antiepileptic drugs – American Academy of Neurology and the American Epilepsy Society
Part I: Treatment of new-onset epilepsy (free PDF)
Part II: Treatment-resistant epilepsy (free PDF)
Commentary: New Epilepsy Guidelines Shed Light on Explosion of New Drugs – MedPage Today (free registration required)
ASCO Resource-Stratified Practice Guideline: Palliative Care in the Global Setting
18 Jun, 2018 | 00:20h | UTCCommentary: ASCO Guideline Addresses Palliative Care in the Global Setting – ASCO Daily News (free)
Guide: Age-attuned Hospice Care
18 Jun, 2018 | 00:19h | UTCAge-attuned Hospice care: An opportunity to better end of life care for older people – StCristopher’s (free PDF) (via @hospicedoctor see tweet)
“Despite the evidence that more people will die of frailty and multiple long-term conditions than of cancer, our services for those moving towards the end of their life remain focussed on the needs of the latter group”
AMA Guide: Caring for the Caregiver
18 Jun, 2018 | 00:17h | UTCCaring for the caregiver: A guide for physicians – American Medical Association (free PDF)
Commentary: AMA Releases New Physician Guide on Caring for the Caregiver – The ASCO Post (free)
Register-based Retrospective Cohort: Perioperative Red Blood Cell Transfusions Associated with Venous Thromboembolism
18 Jun, 2018 | 00:16h | UTCAssociation of Perioperative Red Blood Cell Transfusions With Venous Thromboembolism in a North American Registry – JAMA Surgery (free for a limited period)
Commentary: Peri-Op RBC Transfusions Linked to Postoperative VTE – MPR (free) AND Risk for Clot Increases After Surgery With Transfusion – Medscape (free registration required) AND Post-Op VTE Risk Up After Intra-Op Blood Transfusion – MedPage Today (free registration required) AND VTE Risk Higher in Surgical Patients Who Get Transfusions – TCTMD (free)
Systematic Review: Noninvasive Nonpharmacological Treatment for Chronic Pain
15 Jun, 2018 | 02:28h | UTCSee also: Evidence Summary (free PDF) and Full Report (free PDF)
Controversy: Is there still a place for the Swan-Ganz catheter?
15 Jun, 2018 | 02:28h | UTCControversy: Is there still a place for the Swan-Ganz catheter? – Intensive Care Medicine
YES (free for a limited period) / NO (free for a limited period) WE ARE NOT SURE (free for a limited period)
USPSTF Draft Statement: Screening for Unhealthy Alcohol Use in Adolescents and Adults
15 Jun, 2018 | 02:27h | UTCCommentary: USPSTF Again Recommends Screening for Unhealthy Alcohol Use in Adults – NEJM Physician’s First Watch (free)
Guideline Revisited: Diagnosis and Management of Primary Aldosteronism
15 Jun, 2018 | 02:25h | UTCRelated Guideline: The Management of Primary Aldosteronism: Case Detection, Diagnosis, and Treatment: An Endocrine Society Clinical Practice Guideline – The Journal of Clinical Endocrinology & Metabolism (free)