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Cluster Randomized Trial: Management of Multimorbidity Using a Patient-Centered Care Model

6 Jul, 2018 | 03:23h | UTC

Management of multimorbidity using a patient-centred care model: a pragmatic cluster-randomised trial of the 3D approach – The Lancet (free)

Commentaries: Patient-centred care for multimorbidity: an end in itself? – The Lancet (free) AND Results of the largest ever multimorbidity trial in primary care challenge current thinking -NIHR News (free)

Related: Designing a High-Performing Health Care System for Patients with Complex Needs: Ten Recommendations for Policymakers (series of free articles on the topic) AND Multimorbidity: A Priority for Global Health Research (free report and commentaries)

“In the largest ever trial of an intervention to treat people with multiple long-term conditions (multimorbidity) in primary care, NIHR-researchers found that the patient-centred approach taken improved patients’ experience of their care but did not improve their health-related quality of life. This is a challenge to current thinking on which UK and international guidelines are based”. (from NIHR News)

Richard Lehman’s journal review – 2 July 2018

6 Jul, 2018 | 03:28h | UTC

Richard Lehman’s journal review, 2 July 2018 – The BMJ Opinion (free)

Richard Lehman reviews the latest research in the top medical journals.

Cohort Study: Coffee Drinking and Mortality

6 Jul, 2018 | 03:22h | UTC

Association of Coffee Drinking With Mortality by Genetic Variation in Caffeine Metabolism: Findings From the UK Biobank – JAMA Internal Medicine (link to abstract – $ for full-text)

Commentaries: Expert reaction to research association between coffee and lower risk of death – Science Media Centre (free) AND Fresh grounds for coffee: Study shows it may boost longevity – Associated Press (free) AND Coffee Drinkers Are More Likely To Live Longer. Decaf May Do The Trick, Too – NPR (free)

Related Studies: Meta-Analysis: Coffee consumption and health (free research and commentaries) AND Coffee Drinking and Mortality Studies (link to abstract and commentaries)

Another observational study showing possible benefits from drinking coffee.

Cohort Study: Endocrine Late Effects in Survivors of Cancer in Adolescence and Young Adulthood

6 Jul, 2018 | 03:21h | UTC

Endocrine Late Effects in Survivors of Cancer in Adolescence and Young Adulthood: A Danish Population-Based Cohort Study – JAMA Network Open (free)

Invited Commentary: Unmet Survivorship Care Needs of Adolescent and Young Adult Cancer Survivors (free)

Review: Cardiovascular Toxicity in Cancer Survivors

6 Jul, 2018 | 03:20h | UTC

Cardiovascular Toxicity in Cancer Survivors: Current Guidelines and Future Directions – American College of Cardiology (free)

Opinion: Why Do-It-Yourself Blood Tests are a Bad Idea

6 Jul, 2018 | 03:16h | UTC

Why do-it-yourself blood tests are a bad idea – Common Sense Family Doctor (free)

“Routine blood testing in healthy people has numerous downsides that Holmes never mentioned, including poor predictive value, false positives, and overdiagnosis” (from Common Sense Family Doctor)

“When you go about testing everyone for everything, you don’t create a world of healthy people….you create a nightmare where everyone is sick” (from The BMJ Opinion)

Perspective: Four Principles to Make Evidence Synthesis More Useful for Policy

6 Jul, 2018 | 03:14h | UTC

Four principles to make evidence synthesis more useful for policy – Nature (free)

“Reward the creation of analyses for policymakers that are inclusive, rigorous, transparent and accessible, urge Christl A. Donnelly and colleagues”.

Systematic Review: Continuity of Care and Mortality

6 Jul, 2018 | 03:17h | UTC

Continuity of care with doctors—a matter of life and death? A systematic review of continuity of care and mortality – BMJ Open (free)

Commentaries: Seeing same doctor every time ‘reduces risk of death’ – NHS Choices (free) AND Sticking with 1 doctor could have health benefits: Study – UPI (free)

Review: Management of Irritable Bowel Syndrome

6 Jul, 2018 | 03:13h | UTC

American College of Gastroenterology Monograph on Management of Irritable Bowel Syndrome – American Journal of Gastroenterology (free for a limited period)

Clinical Practice Guidelines for Irritable Bowel Syndrome in Korea, 2017 Revised Edition – Journal of Neurogastroenterology and Motility (free) AND Evidence-based clinical practice guidelines for irritable bowel syndrome – Journal of Gastroenterology (free)

Source: NewsWise

CDC Guideline: Use of Once-Weekly Isoniazid-Rifapentine Regimen to Treat Latent TB Infection

6 Jul, 2018 | 03:12h | UTC

Update of Recommendations for Use of Once-Weekly Isoniazid-Rifapentine Regimen to Treat Latent Mycobacterium tuberculosis Infection – Centers for Disease Control and Prevention (free)

Commentary: CDC Updates Guidelines on Weekly Therapy for Latent TB Infection – Physician’s First Watch (free)

Related WHO Guideline: Latent TB Infection (free guideline and news release)

Perspective: Scientists on Twitter

6 Jul, 2018 | 03:15h | UTC

Scientists on Twitter: Preaching to the choir or singing from the rooftops? – Facets (free)

“Great new study about science outreach via Twitter: Initially, scientists mostly tweet to each other. But after accumulating about 1000 followers, scientists reach an increasing number of journalists, policy makers, and other members of the public”. (via @JSheltzer see Tweet)

Study: The Plateau of Human Mortality

6 Jul, 2018 | 03:11h | UTC

The plateau of human mortality: Demography of longevity pioneers – Science (link to abstract – $ for full-text)

Commentaries: There’s no limit to longevity, says study that revives human lifespan debate – Nature News (free) AND Italian study suggests human lifespan could continue increasing – NHS Choices (free) AND Age 105? Then you’ve a better chance of living even longer – The Guardian (free) AND How Long Can We Live? The Limit Hasn’t Been Reached, Study Finds – The New York Times (free)

Study: Global Burden of Diabetes Attributable to Air Pollution

6 Jul, 2018 | 03:07h | UTC

The 2016 global and national burden of diabetes mellitus attributable to PM_2·5 air pollution – The Lancet Planetary Health (free)

Commentaries: Air pollution and diabetes: it’s time to get active! – The Lancet Planetary Health (free) AND Air pollution linked to 3.2 million new diabetes cases in one year – CNN (free) AND Air pollution contributes significantly to diabetes globally – Washington University School of Medicine (free)

Related: WHO Report: 9 out of 10 People Worldwide Breathe Polluted Air (free report and commentaries) AND Ambient Air Pollution in Relation to Diabetes (free research) AND The Lancet Commission on pollution and health (free resources) AND Air Pollution and Mortality (free research and commentaries) AND Global burden of disease attributable to ambient air pollution (free report and commentaries) AND 5.5 million lives were lost in 2013 to diseases associated with Air Pollution (free report and infographic)

Systematic Review: Treatments for Heart Failure with Preserved Ejection Fraction

6 Jul, 2018 | 03:08h | UTC

Beta-blockers and inhibitors of the renin-angiotensin aldosterone system for chronic heart failure with preserved ejection fraction – Cochrane Library (free)

Summary: Beta-blockers and inhibitors of the renin-angiotensin aldosterone system for chronic heart failure with preserved ejection fraction – Cochrane Library (free)

This Cochrane review suggests mineralocorticoid receptor antagonists may be of benefit to reduce hospitalizations, while the meta-analysis in Heart suggests beta-blockers may improve all-cause and cardiovascular mortality…