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Meta-Analysis: Comparative Benefits and Harms of Basal Insulin Analogues for Type 2 Diabetes

13 Jul, 2018 | 02:46h | UTC

Comparative Benefits and Harms of Basal Insulin Analogues for Type 2 Diabetes: A Systematic Review and Network Meta-analysis – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries: Newer, older insulin formulations may offer similar glucose-lowering effects – ACP Internist (free) AND HbA1c Reduction Similar in Old, New Basal Insulin Analogues – MedPage Today (free registration required)

USPSTF Statement: Risk Assessment for Cardiovascular Disease With Nontraditional Risk Factors

13 Jul, 2018 | 02:48h | UTC

Risk Assessment for Cardiovascular Disease With Nontraditional Risk Factors: US Preventive Services Task Force Recommendation Statement – JAMA (free)

Editorial: USPSTF Recommendations for Assessment of Cardiovascular Risk With Nontraditional Risk Factors: Finding the Right Tests for the Right Patients (free)

“The USPSTF concludes that the current evidence is insufficient to assess the balance of benefits and harms of adding the ankle-brachial index (ABI), high-sensitivity C-reactive protein (hsCRP) level, or coronary artery calcium (CAC) score to traditional risk assessment for cardiovascular disease (CVD) in asymptomatic adults to prevent CVD events”.

Meta-Analysis: Multivitamins Do Not Reduce Cardiovascular Disease and Mortality

13 Jul, 2018 | 02:47h | UTC

Association of Multivitamin and Mineral Supplementation and Risk of Cardiovascular Disease: A Systematic Review and Meta-Analysis – Circulation: Cardiovascular Quality and Outcomes (free for a limited period)

Editorial: Multivitamins Do Not Reduce Cardiovascular Disease and Mortality and Should Not Be Taken for This Purpose: How Do We Know That? (free)

Commentaries: Study: Multivitamins Do Not Prevent Strokes, Heart Attacks or Cardiovascular Disease Deaths – University of Alabama at Birmingham, via NewsWise (free) AND Multivitamin-mineral supplements do not reduce heart disease, deaths – Reuters (free)

Related: Supplements Not Effective for CVD Prevention and Treatment (link to abstract and commentaries) AND Multivitamins are probably a waste of money (free commentaries)

Review: Optimal Pain Management for Patients with Cancer in the Modern Era

13 Jul, 2018 | 02:42h | UTC

Optimal pain management for patients with cancer in the modern era – CA: A Cancer Journal of Clinicians (free)

Study: Association of Early Introduction of Solids with Infant Sleep

13 Jul, 2018 | 02:45h | UTC

Association of Early Introduction of Solids With Infant Sleep: A Secondary Analysis of a Randomized Clinical Trial – JAMA Pediatrics (free)

Author Interview: Effects of Early Solid Food Introduction on Infant Sleep (free audio)

Commentaries: Babies fed solids earlier ‘sleep better’ – NHS Choices (free) AND Feeding your baby solids early may help them sleep, study suggests – The Guardian (free) AND Giving your baby solid food early won’t help them sleep better – The Conversation (free)

Review: Update on Infection Control Practices in Cancer Hospitals

13 Jul, 2018 | 02:43h | UTC

Update on infection control practices in cancer hospitals – CA: A Cancer Journal of Clinicians (free)

Randomized Trial: Effect of a Continuous ECG Monitoring Patch on Detection of Undiagnosed Atrial Fibrillation

13 Jul, 2018 | 02:44h | UTC

Effect of a Home-Based Wearable Continuous ECG Monitoring Patch on Detection of Undiagnosed Atrial Fibrillation: The mSToPS Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)

Video: Effect of a Home-Based Wearable ECG Patch Monitor on Detection of Undiagnosed Atrial Fibrillation in Individuals at Increased Risk of Atrial Fibrillation (free)

Commentary: If You Look For Atrial Fibrillation You Will Find Atrial Fibrillation – Cardiobrief (free)

Cohort Study: Periconception Glycemic Control in Women with Type 1 Diabetes and Risk of Major birth defects

13 Jul, 2018 | 02:41h | UTC

Periconception glycaemic control in women with type 1 diabetes and risk of major birth defects: population based cohort study in Sweden – The BMJ (free)

Commentary: Higher risk of heart defects in babies of mothers with type 1 diabetes – Karolinska Institutet, via EurekAlert (free)

Review: Public Health Implications of Overscreening for Carotid Artery Stenosis, Prediabetes, and Thyroid Cancer

13 Jul, 2018 | 02:40h | UTC

Public health implications of overscreening for carotid artery stenosis, prediabetes, and thyroid cancer – Public Health Reviews (free)

Consensus Report: Returning Individual Research Results to Participants

13 Jul, 2018 | 02:38h | UTC

Returning Individual Research Results to Participants: Guidance for a New Research Paradigm (2018) – National Academies of Sciences, Engineering, and Medicine (free PDF)

Commentaries: National Academies panel urges researchers to routinely share test results with study participants – STAT (free) AND If you give your DNA and tissues to science, should you get a peek at what they might contain? – Science (free) AND New report says individual research results should be shared with participants more often – National Academies of Sciences, Engineering, and Medicine, via EurekAlert (free)

Related Viewpoint: Return of Research Results to Study Participants: Uncharted and Untested – JAMA (free for a limited period)

Summary of the International Guidelines for the Management of Hospital-acquired and Ventilator-acquired Pneumonia

13 Jul, 2018 | 02:38h | UTC

Summary of the international clinical guidelines for the management of hospital-acquired and ventilator-acquired pneumonia – ERJ Open Research (free)

Editorial: Treating nosocomial pneumonia: what’s new (free)

Source: Critical Care Reviews Newsletter

Guideline: Recommendations on Screening for Asymptomatic Bacteriuria in Pregnancy

13 Jul, 2018 | 02:37h | UTC

Recommendations on screening for asymptomatic bacteriuria in pregnancy – Canadian Task Force on Preventive Health Care (free)

NICE Draft Guidance: Antibiotics Should be Restricted for COPD

13 Jul, 2018 | 02:36h | UTC

Antibiotics should be restricted for COPD – National Institute for Health and Care Excellence (free)

Commentaries: Antibiotics should be restricted for COPD, says NICE – OnMedica (free) AND UK officials recommend limits on antibiotics for COPD – CIDRAP (free)

“The draft antimicrobial guidance recommends that antibiotics should be offered to people who have a severe flare up of symptoms, also known as a severe acute exacerbation”

Richard Lehman’s journal review – 9 July 2018

13 Jul, 2018 | 02:34h | UTC

Richard Lehman’s journal review, 9 July 2018 – The BMJ Opinion (free)

Richard Lehman reviews the latest research in the top medical journals

Authors’ Reply: Percutaneous Coronary Intervention for Stable Angina in ORBITA

13 Jul, 2018 | 02:33h | UTC

Percutaneous coronary intervention for stable angina in ORBITA – Authors’ reply – The Lancet (free)

Original study: Percutaneous coronary intervention in stable angina (ORBITA) (link to abstract and commentaries)

Related research: Research: Physiology-Stratified Analysis of ORBITA (free research and commentaries)

Oposition to Breast-Feeding Resolution by U.S. Stuns World Health Officials

13 Jul, 2018 | 02:35h | UTC

Oposition to Breast-Feeding Resolution by U.S. Stuns World Health Officials – The New York Times (10 articles per month are free)

Randomized Trial: Cabozantinib in Patients with Advanced and Progressing Hepatocellular Carcinoma

13 Jul, 2018 | 02:33h | UTC

Cabozantinib in Patients with Advanced and Progressing Hepatocellular Carcinoma – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Cabozantinib in Hepatocellular Carcinoma – NEJM Resident 360 (free)

Median overall survival was 10.2 months with cabozantinib and 8.0 months with placebo, but the rate of high-grade adverse events in the cabozantinib group was approximately twice that observed in the placebo group.