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Randomized Trial: Epinephrine in Out-of-Hospital Cardiac Arrest
20 Jul, 2018 | 03:19h | UTCEditorial: Testing Epinephrine for Out-of-Hospital Cardiac Arrest (free)
Commentary: Using adrenaline in cardiac arrests results in less than 1 percent more people leaving hospital alive – University of Warwick, via EurekAlert (free)
See also: Infographic detailing result findings (free)
“A clinical trial of the use of adrenaline in cardiac arrests has found that its use results in less than 1% more people leaving hospital alive – but almost doubles the risk of severe brain damage for survivors of cardiac arrest” (from University of Warwick).
Meta-Analysis: Global Burden of CV Disease in People Living with HIV
20 Jul, 2018 | 03:04h | UTCCommentaries: HIV infection doubles risk of heart disease – University of Edinburgh, via ScienceDaily (free) AND Global Burden of HIV-Related CVD Has Tripled Over Two Decades – TCTMD (free)
Systematic Review: Association Between Nurse Staffing and Omissions in Nursing Care
20 Jul, 2018 | 03:05h | UTCCommentary: Nurse staffing levels linked to reports of missed care in adult wards – NIHR Signal (free)
ESMO Guideline: Management of Constipation in Advanced Cancer
20 Jul, 2018 | 03:06h | UTC
Perspective: Contrary to Common Belief, Randomized Controlled Trials Inevitably Produce Biased Results
20 Jul, 2018 | 03:02h | UTCOriginal Article: Why all randomised controlled trials produce biased results – Annals of Medicine (free)
Source: Nature Briefing Newsletter
Meta-Analysis: Cognitive Behavioral Therapy for Anxiety and Related Disorders
20 Jul, 2018 | 03:00h | UTCCommentary: CBT for anxiety: new meta-analysis confirms significant improvements to target symptoms – The Mental Elf (free) (via @AllenFrancesMD)
Report: Feeding in the First Year of Life
20 Jul, 2018 | 03:03h | UTCFeeding in the first year of life – Scientific Advisory Committee on Nutrition (SACN) (free)
Commentaries: SACN publishes ‘Feeding in the first year of life’ report – Public Health England (free) AND Too many babies overfed, experts fear – BBC (free)
Guideline: Treatment of Chronic Lymphocytic Leukemia
20 Jul, 2018 | 02:52h | UTC
Cohort Study: Are Electronic Nicotine Delivery Systems Helping Cigarette Smokers Quit?
20 Jul, 2018 | 02:59h | UTCCommentaries: More Than 90 Percent Of Smokers Using E-cigarettes Still Smoking A Year Later – Georgia State University (free) AND Study casts doubt on effectiveness of e-cigs for smoking cessation – National Institutes of Health (free) AND Vaping May Not Help Smokers Kick the Habit – MedPage Today (free registration required)
Study: Association of Digital Media Use with ADHD Among Adolescents
20 Jul, 2018 | 02:54h | UTCAssociation of Digital Media Use With Subsequent Symptoms of Attention-Deficit/Hyperactivity Disorder Among Adolescents – JAMA (link to abstract – $ for full-text)
Commentaries: More Screen Time For Teens Linked To ADHD Symptoms – NPR (free) AND Digital media use linked to behavioral problems in kids – University of Southern California, via ScienceDaily (free) AND Screen time linked to ADHD symptoms in teens – Reuters (free) AND ADHD study links teens’ symptoms with digital media use – CNN (free) AND Expert reaction to association of digital media use and ADHD symptoms among teenagers – Science Media Centre (free)
Perspective: “Is There a Doctor on the Plane?”
20 Jul, 2018 | 02:53h | UTC“Is There a Doctor on the Plane?” – JAMA (free for a limited period)
Interview: “Is There a Doctor on the Plane?” (free)
Study: Clinical Trial Evidence Supporting FDA Approval of Drugs Granted Breakthrough Therapy Designation
20 Jul, 2018 | 02:50h | UTCClinical Trial Evidence Supporting FDA Approval of Drugs Granted Breakthrough Therapy Designation – JAMA (link to abstract – $ for full-text)
Commentaries: Are ‘breakthrough’ drugs as safe as other FDA-approved medicines? – CNN (free) AND Evidence to support ‘breakthrough’ drugs often very limited: study – Reuters (free)
Report – Open Science by Design: Realizing a Vision for 21st Century Research
20 Jul, 2018 | 02:51h | UTCNews Release: Report Proposes Recommendations and New Framework to Speed Progress Toward Open Science (free)
Review: Auscultation for Bowel Sounds in Patients with Ileus
20 Jul, 2018 | 02:46h | UTCEditorial: It’s not a gut feeling: don’t listen to the bowels (free PDF)
Source: Critical Care Reviews Newsletter
Head To Head: Does Evidence Based Medicine Adversely Affect Clinical Judgment?
20 Jul, 2018 | 02:49h | UTCDoes evidence based medicine adversely affect clinical judgment? – The BMJ (free) (via @michelaccad)
Systematic Review: Harms Reporting in Trials with Probiotics
20 Jul, 2018 | 02:48h | UTCHarms Reporting in Randomized Controlled Trials of Interventions Aimed at Modifying Microbiota: A Systematic Review – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Reporting on risks often inadequate for prebiotics, probiotics, synbiotics – ACP Internist (free) AND Probiotics studies often don’t disclose safety data or risks, report finds – STAT (free) AND Safety of Probiotic Supplements Is Not Guaranteed, Study Says – Consumer Reports (free)
“How to make an intervention safe? Don’t report the adverse events”. (via @EricTopol see Tweet)
Review: Noninvasive Ventilation in Acute Respiratory Failure
20 Jul, 2018 | 02:47h | UTCSource: Critical Care Reviews Newsletter
Systematic Review: Nurses as Substitutes for Doctors in Primary Care
20 Jul, 2018 | 02:44h | UTCNurses as substitutes for doctors in primary care – Cochrane Library (free)
Summary: Nurses as substitutes for doctors in primary care – Cochrane Library (free)
“This updated Cochrane Review indicates that nurses can effectively expand the capacity of the primary care workforce”.
Cohort Study: Occult Blood in Feces is Associated with All-cause and Non-colorectal Cancer Mortality
20 Jul, 2018 | 02:46h | UTCOccult blood in faeces is associated with all-cause and non-colorectal cancer mortality – Gut (free)
Commentaries: FOB associated with rise in all-cause mortality – OnMedica (free) AND 3 key findings from Gut study on all-cause mortality associated with occult blood in stool – GI & Endoscopy (free) AND Fecal Occult Blood Flags Risks Beyond Colon Cancer – MedPage Today (free)
WHO: 9 in 10 Infants Worldwide Received Vaccinations in 2017
20 Jul, 2018 | 02:29h | UTC9 in 10 infants worldwide received vaccinations in 2017 – World Health Organization (free)
Clinical Review: Novel Therapies for Diabetes Mellitus in Pregnancy
20 Jul, 2018 | 02:42h | UTCNovel therapies for diabetes mellitus in pregnancy – The BMJ (free for a limited period)
Study: Overprescription of Antibiotics in Urgent Care Clinics
20 Jul, 2018 | 02:43h | UTCComparison of Antibiotic Prescribing in Retail Clinics, Urgent Care Centers, Emergency Departments, and Traditional Ambulatory Care Settings in the United States – JAMA Internal Medicine (free for a limited period)
Commentaries: Overprescription in Urgent Care Clinics—The Fast and the Spurious – JAMA Internal Medicine (free for a limited period) AND Urgent care centers often prescribe unnecessary antibiotics – Reuters (free) AND Study spotlights inappropriate prescribing in urgent care – CIDRAP (free)
Report: Integrating Responses at the Intersection of Opioid Use Disorder and Infectious Disease Epidemics
20 Jul, 2018 | 02:29h | UTCCommentaries: National Academies target opioid abuse and infectious disease consequences – Emory Health Sciences (free) AND Within opioid abuse epidemic, infectious disease epidemic emerges – Reuters (free)
Perspective: Is Your Cellphone Giving you Cancer?
20 Jul, 2018 | 02:26h | UTCIs your cellphone giving you cancer? A comprehensive guide to the messy, frustrating research – VOX (free)
Richard Lehman’s Journal Review – 16 July 2018
20 Jul, 2018 | 02:28h | UTCRichard Lehman’s journal review, 16 July 2018 – The BMJ Opinion (free)
Richard Lehman reviews the latest research in the top medical journals.