All Posts

BTS Guideline: Outpatient Management of Pulmonary Embolism

18 Jun, 2018 | 00:26h | UTC

British Thoracic Society Guideline for the initial outpatient management of pulmonary embolism (PE) – Thorax (free)

Randomized Trial: Fluid Infusion Rates for Pediatric Diabetic Ketoacidosis

18 Jun, 2018 | 00:24h | UTC

Clinical Trial of Fluid Infusion Rates for Pediatric Diabetic Ketoacidosis – New England Journal of Medicine (link to abstract – $ for full-text)

Quick Take Video Summary: Does Infusion Rate Affect Neurologic Outcomes in Pediatric DKA? (free)

Commentaries: PEM Practice Changing Paper: Clinical Trial of Fluid Infusion Rates for Pediatric DKA – Aliem (free) AND The Rate of Resuscitation in Pediatric DKA – Emergency Medicine Literature of Note (free) AND Infusion Type Doesn’t Affect Brain Outcomes in Pediatric DKA – Medscape (free)

Randomized Trial: Coronary CT Angiography vs Stress Echocardiography in Acute Chest Pain

18 Jun, 2018 | 00:22h | UTC

Coronary Computed Tomography Angiography Versus Stress Echocardiography in Acute Chest Pain: A Randomized Controlled Trial – JACC: Cardiovascular Imaging (link to abstract – $ for full-text)

Commentary: The Patient Presenting With Chest Pain: Stress Echo Gives Coronary CTA a Run for Its Money – TCTMD (free)

Guideline: Efficacy and Tolerability of the New Antiepileptic Drugs

18 Jun, 2018 | 00:21h | UTC

Practice guideline update summary: Efficacy and tolerability of the new antiepileptic drugs – American Academy of Neurology and the American Epilepsy Society

Part I: Treatment of new-onset epilepsy (free PDF)

Part II: Treatment-resistant epilepsy (free PDF)

Commentary: New Epilepsy Guidelines Shed Light on Explosion of New Drugs – MedPage Today (free registration required)

ASCO Resource-Stratified Practice Guideline: Palliative Care in the Global Setting

18 Jun, 2018 | 00:20h | UTC

Palliative Care in the Global Setting: ASCO Resource-Stratified Practice Guideline – Journal of Global Oncology (free)

Commentary: ASCO Guideline Addresses Palliative Care in the Global Setting – ASCO Daily News (free)

Guide: Age-attuned Hospice Care

18 Jun, 2018 | 00:19h | UTC

Age-attuned Hospice care: An opportunity to better end of life care for older people – StCristopher’s (free PDF) (via @hospicedoctor see tweet)

“Despite the evidence that more people will die of frailty and multiple long-term conditions than of cancer, our services for those moving towards the end of their life remain focussed on the needs of the latter group”

AMA Guide: Caring for the Caregiver

18 Jun, 2018 | 00:17h | UTC

Caring for the caregiver: A guide for physicians – American Medical Association (free PDF)

Commentary: AMA Releases New Physician Guide on Caring for the Caregiver – The ASCO Post (free)

Register-based Retrospective Cohort: Perioperative Red Blood Cell Transfusions Associated with Venous Thromboembolism

18 Jun, 2018 | 00:16h | UTC

Association of Perioperative Red Blood Cell Transfusions With Venous Thromboembolism in a North American Registry – JAMA Surgery (free for a limited period)

Commentary: Peri-Op RBC Transfusions Linked to Postoperative VTE – MPR (free) AND Risk for Clot Increases After Surgery With Transfusion – Medscape (free registration required) AND Post-Op VTE Risk Up After Intra-Op Blood Transfusion – MedPage Today (free registration required) AND VTE Risk Higher in Surgical Patients Who Get Transfusions – TCTMD (free)

Systematic Review: Noninvasive Nonpharmacological Treatment for Chronic Pain

15 Jun, 2018 | 02:28h | UTC

Noninvasive Nonpharmacological Treatment for Chronic Pain: A Systematic Review – Agency for Healthcare Research and Quality (free)

See also: Evidence Summary (free PDF) and Full Report (free PDF)

Controversy: Is there still a place for the Swan-Ganz catheter?

15 Jun, 2018 | 02:28h | UTC

Controversy: Is there still a place for the Swan-Ganz catheter? – Intensive Care Medicine

YES (free for a limited period) / NO (free for a limited period) WE ARE NOT SURE (free for a limited period)

USPSTF Draft Statement: Screening for Unhealthy Alcohol Use in Adolescents and Adults

15 Jun, 2018 | 02:27h | UTC

Unhealthy Alcohol Use in Adolescents and Adults: Screening and Behavioral Counseling Interventions – U.S. Preventive Services Task Force (free)

Commentary: USPSTF Again Recommends Screening for Unhealthy Alcohol Use in Adults – NEJM Physician’s First Watch (free)

Guideline Revisited: Diagnosis and Management of Primary Aldosteronism

15 Jun, 2018 | 02:25h | UTC

Diagnosis and management of primary aldosteronism: the Endocrine Society guideline 2016 revisited – European Journal of Endocrinology (free)

Research: IQ Scores Dropping Since the 1970s

15 Jun, 2018 | 02:26h | UTC

Flynn effect and its reversal are both environmentally caused – Proceedings of the National Academy of Sciences (link to abstract – $ for full-text)

Commentaries: Researchers find IQ scores dropping since the 1970s – MedicalXpress (free) AND IQ Scores Are Falling in “Worrying” Reversal of 20th Century Intelligence Boom – Science Alert (free) AND IQ Scores Are Falling Due to Environmental Factors, Study Finds – TIME (free)

Research: Invasive Procedures Associated With the Development of Infective Endocarditis

15 Jun, 2018 | 02:23h | UTC

Invasive Procedures Associated With the Development of Infective Endocarditis – Journal of the American College of Cardiology (link to abstract – $ for full-text)

Commentaries: Infective endocarditis risk increased after many types of medical procedures – ACP Hospitalist (free) AND Many Invasive Procedures, Including Cardiovascular, Up Risk of Infective Endocarditis – TCTMD (free) AND Invasive procedures—including cardiovascular—boost risk of endocarditis – Cardiovascular Business (free) AND Endocarditis: Any Invasive Procedure Is a Risk – MedPage Today (free registration required)

Review: Optimal Duration of Dual Antiplatelet Therapy for Coronary Artery Disease

15 Jun, 2018 | 02:24h | UTC

Optimal duration of dual antiplatelet therapy for coronary artery disease – Netherlands Heart Journal (free)

Randomized Trial: Increased Supervision of Medical Residents Not Associated with Reduced Medical Errors

15 Jun, 2018 | 02:23h | UTC

Effect of Increased Inpatient Attending Physician Supervision on Medical Errors, Patient Safety, and Resident Education: A Randomized Clinical Trial – JAMA Internal Medicine (link to abstract – $ for full-text)

Commentaries: Effect of increased inpatient attending physician supervision on medical errors, patient safety, and resident education: a randomized clinical trial – PSNet (free) AND Increased attending supervision on rounds didn’t significantly reduce medical errors – ACP Hospitalist (free) AND Additional physician resident supervision doesn’t improve patient safety – Modern Healthcare (free) AND Closer Resident Supervision Does Not Reduce Medical Errors – Medscape (free registration required) AND Is More Supervision of Medical Residents Always Better for Patient Care? – MedicalResearch.com (free)

The WHO Essential Diagnostic List: A Tool for the Future

15 Jun, 2018 | 02:22h | UTC

The WHO essential diagnostic list: a tool for the future – BMJ Global Health Blog (free)

See Original WHO Report: List of Essential In Vitro Diagnostics First edition (2018) – World Health Organization (free report and news release)

Cohort Study: Antifungal Drug in Pregnancy Not Associated with Increased Risk of Stillbirth and Neonatal Death

15 Jun, 2018 | 02:21h | UTC

Oral Fluconazole in Pregnancy and Risk of Stillbirth and Neonatal Death – JAMA (link to abstract – $ for full-text)

Commentaries: No link found between oral antifungal drug and stillbirth – Karolinska Institutet, via ScienceDaily (free) AND Antifungal Use During Pregnancy and Risk of Stillbirth: What’s the Link? – MPR (free) AND Study Finds No Link Between Fluconazole During Pregnancy and Stillbirth or Neonatal Death – MedicalResearch.com (free) AND Oral Fluconazole for Thrush in Pregnancy Doesn’t Up Stillbirth – Medscape (free registration required)

Retraction and Republication: PREDIMED Study on Mediterranean Diet

15 Jun, 2018 | 02:19h | UTC

Retraction and Republication: Primary Prevention of Cardiovascular Disease with a Mediterranean Diet Supplemented with Extra-Virgin Olive Oil or Nuts – New England Journal of Medicine (free)

Correspondence: Retraction and Republication: Primary Prevention of Cardiovascular Disease with a Mediterranean Diet. N Engl J Med 2013;368:1279-90 (free)

Commentaries: That Huge Mediterranean Diet Study Was Flawed. But Was It Wrong? – New York Times (free) AND Errors Trigger Retraction Of Study On Mediterranean Diet’s Heart Benefits – NPR (free) AND Expert reaction to retraction and republication of study looking at Mediterranean diet and heart disease – Science Media Centre (free)

Randomized Trial: Negative Pressure Wound Therapy No Better Than Regular Dressing in Severe Open Fracture of the Lower Limb

15 Jun, 2018 | 02:20h | UTC

Effect of Negative Pressure Wound Therapy vs Standard Wound Management on 12-Month Disability Among Adults With Severe Open Fracture of the Lower Limb: The WOLLF Randomized Clinical Trial – JAMA (free for a limited period)

Commentaries: High-tech treatment of open leg wounds no better than using regular dressings – University of Warwick (free) AND Negative-Pressure Therapy No Better for Open Fractures – Medscape (free registration required)

“Negative pressure wound therapy did not improve 12-month disability for patients with severe open fracture of the lower limb compared with standard wound dressing”

Case-cohort Study: Evidence of Higher Risk of Severe Dengue in Vaccinated Persons Not Previously Exposed to Dengue

15 Jun, 2018 | 02:16h | UTC

Effect of Dengue Serostatus on Dengue Vaccine Safety and Efficacy – New England Journal of Medicine (free)

Perspective: Trolleyology and the Dengue Vaccine Dilemma – New England Journal of Medicine (free)

Commentaries: Study confirms higher risk of dengue in kids who got Sanofi vaccine – Reuters (free) AND Sanofi’s new dengue challenge: find a diagnostic that will make its vaccine safe to use – STAT (free)