All Posts
Randomized Trial: Letters with Peer Comparison May Reduce Overprescribing
17 Aug, 2018 | 02:34h | UTCEffect of Peer Comparison Letters for High-Volume Primary Care Prescribers of Quetiapine in Older and Disabled Adults: A Randomized Clinical Trial – JAMA Psychiatry (link to abstract – $ for full-text)
Commentaries: Behavioral nudges lead to striking drop in prescriptions of potent antipsychotic – Columbia University’s Mailman School of Public Health, via ScienceDaily (free) AND Study Reduces Over-prescription of Antipsychotics in Older Adults – Mad in America (free) AND ‘Dear Doctor’ Letters Use Peer Pressure, Government Warning To Stop Overprescribing – NPR (free) AND Peer Pressure Tactic Successfully Curbs Overprescribing – Medscape (free registration required)
Guideline: Prevention and Management of Pain, Agitation/Sedation, Delirium, Immobility, and Sleep Disruption in the ICU
17 Aug, 2018 | 02:32h | UTCClinical Practice Guidelines for the Prevention and Management of Pain, Agitation/Sedation, Delirium, Immobility, and Sleep Disruption in Adult Patients in the ICU – Critical Care Medicine (free) (via @Abraham_RMI)
Study: Association of Compensation to Physicians From Industry and Self-declared Conflict of Interest
17 Aug, 2018 | 02:30h | UTCAssociation of Compensation From the Surgical and Medical Device Industry to Physicians and Self-declared Conflict of Interest – JAMA Surgery (free for a limited period)
Author Interview: Association of Compensation to Physicians From Industry and Self-declared Conflict of Interest (free)
Commentaries: Safeguarding Against Conflicts of Interest in the Surgical Literature – JAMA Surgery (free for a limited period) AND Financial Ties That Bind: Studies Often Fall Short On Conflict-Of-Interest Disclosures – Kaiser Health News (free)
Study: Changes in Midlife Death Rates Across Racial and Ethnic Groups in the United States
17 Aug, 2018 | 02:29h | UTCInfographic: Why is US Life Expectancy Falling Behind? (free PDF)
Commentary: Life expectancy drops in the US and the UK, rises in Australia, a new study finds – CNN (free)
Study: Trends in Life Expectancy Across High Income Countries
17 Aug, 2018 | 02:29h | UTCEditorial: Reversals in life expectancy in high income countries? (free for a limited period)
Commentaries: Life Expectancy Declining Across High Income Countries – Eurasia Review (free) AND Australians living longer but life expectancy dips in US and UK – The Guardian (free) AND UK life expectancy drops while other western countries improve – NHS Choices (free)
Keeping Up With Cardiology: Old-School Learning Versus the Twittersphere
17 Aug, 2018 | 02:28h | UTCKeeping Up With Cardiology: Old-School Learning Versus the Twittersphere – TCTMD (free)
Related: Scientists on Twitter: Preaching to the choir or singing from the rooftops? – Facets (free) AND Rise of the Tweetorial – Precious Bodily Fluids (free) AND Social Medicine: Twitter in Healthcare – Journal of Clinical Medicine (free) AND University of Twitter? Scientists give impromptu lecture critiquing nutrition research – CBC (free) AND Twitter-Based Medicine: How Social Media is Changing the Public’s View of Medicine – The Health Care Blog (free) AND What’s your doctor reading? How social media is disrupting medical education – National Post (free)
Cohort Study: Risk Factors, Mortality, and Cardiovascular Outcomes in Patients with Type 2 Diabetes
17 Aug, 2018 | 02:26h | UTCRisk Factors, Mortality, and Cardiovascular Outcomes in Patients with Type 2 Diabetes – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: In Type 2 Diabetes, Five Risk Factor Targets Keep MI, Stroke, and Death in Check – TCTMD (free) AND How People With Type 2 Diabetes Can Lower Their Risk of Health Problems – TIME (free) AND T2D, Without Other Risks, Not Tied to Excess Mortality – MedPage Today (free registration required)
Cohort Study: Association of Maternal Insecticide Levels With Autism in Offspring
17 Aug, 2018 | 02:27h | UTCAssociation of Maternal Insecticide Levels With Autism in Offspring From a National Birth Cohort – The American Journal of Psychiatry (link to abstract – $ for full-text)
Commentaries: Autism and DDT: What one million pregnancies can — and can’t — reveal – Nature News (free) AND Epidemiologists Link DDT From The 1970s To Modern Autism Diagnoses – Science 2.0 (free – skeptical point of view on study results)
Meta-Analysis: Absolute Risk and Predictors of the Growth of Acute Spontaneous Intracerebral Hemorrhage
17 Aug, 2018 | 02:25h | UTCCommentary: Brain scan checklist set to boost care for stroke survivors – University of Edinburgh, via EurekAlert (free)
Editorial: Making Diagnostic Tests as Essential as Medicines
17 Aug, 2018 | 02:22h | UTCMaking diagnostic tests as essential as medicines – BMJ Global Health (free)
Related: Report: First-ever WHO List of Essential Diagnostic Tests (free report and news release) AND The WHO Essential Diagnostic List: A Tool for the Future (free commentaries)
Study: Trends in Use of Daily Chest Radiographs Among Patients Receiving Mechanical Ventilation
17 Aug, 2018 | 02:23h | UTCCommentaries: Daily Chest X-Rays Still Overused in Mechanically Ventilated Patients – MedicalResearch.com (free) AND Routine daily CXRs for ventilated patients: de-adoption is lagging – Univadis (free registration required) AND Chest x-rays overused on ventilation patients despite ACR guideline – HealthImaging (free)
Perspective: How Unpaywall is Transforming Open Science
17 Aug, 2018 | 02:21h | UTCHow Unpaywall is transforming open science – Nature News (free)
Related: Unlocking paywalled research papers (legally) (free commentaries) AND Half of papers searched for online are free to read (free)
We have been using the Unpaywall Extension for a while, and it is indeed a handy tool to find free versions (entirely legal) of paywalled articles.
International Registry: Long-Term Prognosis of Patients With Takotsubo Syndrome
17 Aug, 2018 | 02:19h | UTCLong-Term Prognosis of Patients With Takotsubo Syndrome – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Commentaries: Long-Term Prognosis of Takotsubo Syndrome – American College of Cardiology (free) AND How deadly is Takotsubo syndrome? It depends on the trigger – Cardiovascular Business (free)
Related: International Expert Consensus Document on Takotsubo Syndrome (free)
Perspective: Medical Students are Skipping Class in Droves — And Making Lectures Increasingly Obsolete
17 Aug, 2018 | 02:19h | UTCPerspective: Medical students are skipping class in droves — and making lectures increasingly obsolete – STAT (free)
Disease Outbreak News: Ebola virus disease in the Democratic Republic of the Congo
17 Aug, 2018 | 02:16h | UTCRelated: WHO chief calls for end to fighting in Congo to halt Ebola spread – The Guardian (free) AND Ebola cases mounting in DRC as region prepares for more – CIDRAP (free) AND Ebola outbreak shaping up as most dangerous test of world’s ability to respond since global crisis – STAT (free)
Study: Polygenic Scores for Common Diseases Identify Individuals with Risk Equivalent to Monogenic Mutations
17 Aug, 2018 | 02:09h | UTCGenome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations – Nature Genetics (link to abstract – $ for full-text)
Commentaries: Researchers predict risk for common deadly diseases from millions of genetic variants – Broad Institute of MIT and Harvard, ScienceDaily (free) AND Clues to Your Health Are Hidden at 6.6 Million Spots in Your DNA – The New York Times (10 articles per month are free) AND Multi-gene test may find risk for heart disease and more – Associated Press (free) AND A Harvard Scientist Thinks He Has a Gene Test for Heart Attack Risk. He Wants to Give It Away Free – Forbes (free)
Retrospective Cohort: Association Between Traumatic Brain Injury and Risk of Suicide
17 Aug, 2018 | 02:14h | UTCAssociation Between Traumatic Brain Injury and Risk of Suicide – JAMA (link to abstract – $ for full-text)
Commentaries: Traumatic brain injury tied to increased risk of suicide – Reuters (free) AND Risk of Suicide Increases After TBI, Study Finds – Psychiatric News Alert (free) AND Expert reaction to traumatic brain injury and suicide – Science Media Centre (free)
Review: Overdiagnosis in Primary Care
17 Aug, 2018 | 02:10h | UTCState of the Art Review: Overdiagnosis in primary care: framing the problem and finding solutions – The BMJ (free for two weeks)
Guideline: Cancer in People Living with HIV
17 Aug, 2018 | 02:04h | UTC
Research: Treatments for First-Episode Schizophrenia Compared
17 Aug, 2018 | 02:13h | UTCAmisulpride and olanzapine followed by open-label treatment with clozapine in first-episode schizophrenia and schizophreniform disorder (OPTiMiSE): a three-phase switching study – The Lancet Psychiatry (link to abstract – $ for full-text)
Commentaries: Switching Anti-Psychotic Medications Doesn’t Improve Outcomes in First-Episode Schizophrenia Patients – Mount Sinai (free) AND No Benefit of Switching Antipsychotics in Early Schizophrenia – Medscape (free registration required) AND No Gain with Antipsych Meds Switch in Schizophrenia – MedPage Today (free registration required)
Randomized Trial: Low-Dose Triple Combination Antihypertensive Medication vs Usual Care for Blood Pressure Control
17 Aug, 2018 | 02:06h | UTCFixed Low-Dose Triple Combination Antihypertensive Medication vs Usual Care for Blood Pressure Control in Patients With Mild to Moderate Hypertension in Sri Lanka: A Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
Video Summary: Fixed-Dose Combination Pill for Hypertension Treatment in Sri Lanka (free)
Commentaries: Three-in-one pill lowers blood pressure significantly, study says – UPI (free) AND Innovative triple pill significantly lowers blood pressure, study finds – George Institute for Global Health, via EurekAlert (free)
Perspective: The Polypill and the Long Journey to Major Impact
17 Aug, 2018 | 02:05h | UTCRichard Smith: The polypill and the long journey to major impact – The BMJ Opinion (free)
Related Reviews: Strengths and Limitations of Using the Polypill in Cardiovascular Prevention – Current Cardiology Reports (free) AND The polypill approach – An innovative strategy to improve cardiovascular health in Europe – BMC Pharmacology and Toxicology (free)
Perspective: 5 Steps to Unpack a Randomized Trial
17 Aug, 2018 | 02:03h | UTCYoga, Depression, & Clinical Trial Critique 101 – Hilda Bastian, in Absolutely Maybe Blog (free)
“5 steps to unpack a randomized trial!” (via @hildabast, see Tweet)
Lessons for Physicians from ‘The Bleeding Edge’: If You See Something, Say Something
17 Aug, 2018 | 02:04h | UTCOpinion: Lessons for physicians from ‘The Bleeding Edge’: If you see something, say something – STAT (free)
“…physicians must act decisively when they identify the rare outlier in their midst. To do anything less would risk our credibility. Worse still, it could risk the lives of the people we took an oath not to harm.”
Ebola Outbreak News: DRC Ebola Cases Surpass Earlier Outbreak Total, Virus Infects 4 More Health Workers
17 Aug, 2018 | 02:02h | UTCDRC Ebola cases surpass earlier outbreak total, virus infects 4 more health workers – CIDRAP (free)
Related: DRC may provide model for containing future Ebola outbreaks – The Conversation (free)