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Zackary Berger’s journal reviews, 28 August 2018
31 Aug, 2018 | 02:02h | UTCZackary Berger’s journal reviews, 28 August 2018 – The BMJ Opinion (free)
Randomized Trial: Cardiovascular Safety of Lorcaserin in Overweight or Obese Patients
31 Aug, 2018 | 01:58h | UTCCardiovascular Safety of Lorcaserin in Overweight or Obese Patients – New England Journal of Medicine (free for a limited period)
Editorial: Lorcaserin — Elixir or Liability? (free for a limited period)
Commentaries: CAMELLIA-TIMI 61: Weight Loss Drug Lorcaserin Did Not Increase CV Events – American College of Cardiology (free) AND Weight-Loss Drug Lorcaserin Clears Cardiovascular Safety Hurdle: CAMELLIA-TIMI 61 – TCTMD (free) AND Weight loss drug lorcaserin found safe in large study – Reuters (free)
Guiding Principles for the Care of People with or at Risk for Diabetes
31 Aug, 2018 | 02:00h | UTCCommentaries: NIDDK Updates ‘Guiding Principles’ for Diabetes, Prediabetes – Medscape (free registration required) AND NDEP revises principles for managing diabetes, prediabetes – Cardiovascular Business (free)
Related Book: Diabetes in America, 3rd Edition – National Institutes of Health (free reference book, just released)
Randomized Trial: Rivaroxaban for Thromboprophylaxis after Hospitalization for Medical Illness
31 Aug, 2018 | 01:57h | UTCRivaroxaban for Thromboprophylaxis after Hospitalization for Medical Illness – New England Journal of Medicine (free for a limited period)
Commentaries: VTE risk unchanged by rivaroxaban after discharge – The Hospitalist (free) AND MARINER: Rivaroxaban vs. Placebo Post-Discharge in Patients at High Risk For VTE – American College of Cardiology (free) AND MARINER: No Reduction in Death, VTE With Rivaroxaban After Discharge in Medically Ill Patients – Medscape (free registration required)
Review: Acute Clinical Care for Transgender Patients
31 Aug, 2018 | 01:59h | UTCAcute Clinical Care for Transgender Patients – JAMA Internal Medicine (free for a limited period) (via @CarlosdelRio7)
Randomized Trial: Tafamidis Treatment for Patients with Transthyretin Amyloid Cardiomyopathy
31 Aug, 2018 | 01:56h | UTCTafamidis Treatment for Patients with Transthyretin Amyloid Cardiomyopathy – New England Journal of Medicine (free for a limited period)
Editorial: Stabilizing Transthyretin to Treat ATTR Cardiomyopathy (free for a limited period)
Commentaries: Tafamidis, a Transthyretin Stabilizer, Offers Hope for Rare Cardiomyopathy – TCTMD (free) AND ATTR-ACT: Tafamidis Findings Offer Hope For Patients With ATTR-CM – American College of Cardiology (free) AND Drug reduces deaths and hospitalizations from underdiagnosed form of heart failure – Columbia University Irving Medical Center, via EurekAlert (free)
Overview of Cochrane Reviews: Assisted Reproductive Technology
31 Aug, 2018 | 01:51h | UTCAssisted reproductive technology: an overview of Cochrane Reviews – Cochrane Library (free for a limited period)
Study: Coronary CT Angiography and 5-Year Risk of Myocardial Infarction
31 Aug, 2018 | 01:55h | UTCCoronary CT Angiography and 5-Year Risk of Myocardial Infarction – New England Journal of Medicine (free for a limited period)
Commentary: Five Reasons I Don’t Believe an Imaging Test Improves Outcomes – by Dr. John Mandrola, in Medscape (free registration required)
See also an interesting Tweetorial by @AnilMakam, also suggesting caution before adopting this study results in clinical practice.
Perspective: Using a New EHR System to Increase Patient Engagement, Improve Efficiency, and Decrease Cost
31 Aug, 2018 | 01:49h | UTC“Another solution might be to capitalize on patients’ vested interest in their own health care by actively engaging them in the entry of their own medical history information into the EHR.”
Perspective: The Community Health Worker Boom
31 Aug, 2018 | 01:50h | UTCThe Community Health Worker Boom – NEJM Catalyst (free)
“The key question is not whether community health workers are effective, but how we can make them as effective as possible.”
Review: Treatment of Invasive Candidiasis
31 Aug, 2018 | 01:47h | UTCTreatment of Invasive Candidiasis: A Narrative Review – Journal of Fungi (free)
Source: Hospital Medicine Virtual Journal Club
Cochrane Review: Xpert® MTB/RIF Test for Diagnosing Extrapulmonary TB
31 Aug, 2018 | 01:48h | UTCXpert® MTB/RIF assay for extrapulmonary tuberculosis and rifampicin resistance – Cochrane Library (free for a limited period)
Summary: Xpert® MTB/RIF test for diagnosing extrapulmonary tuberculosis and rifampicin resistance – Cochrane Library (free)
Commentary: Cochrane review looks at the accuracy of Xpert® MTB/RIF for the diagnosis of extrapulmonary TB – Liverpool School of Tropical Medicine (free)
Viewpoint: Navigating the Ethical Boundaries of Grateful Patient Fundraising
31 Aug, 2018 | 01:46h | UTCNavigating the Ethical Boundaries of Grateful Patient Fundraising – JAMA (free for a limited period)
Opinion: Publish Peer Reviews
31 Aug, 2018 | 01:47h | UTCPublish peer reviews – Nature News (free)
“Jessica K. Polka and colleagues call on journals to sign a pledge to make reviewers’ anonymous comments part of the official scientific record.”
Study: Emergency Department Visits for Adverse Drug Events from Antibiotics in Children
31 Aug, 2018 | 01:44h | UTCCommentaries: Antibiotic side effects send 70,000 children to ER each year, study says – UPI (free) AND Antibiotic side-effects in kids lead to nearly 70,000 ER visits in the US each year – Pediatric Infectious Diseases Society, via ScienceDaily (free)
PURE Study: Redefined ‘High-Quality’ Diet Lowers Risk of All-Cause Mortality
31 Aug, 2018 | 01:43h | UTCRedefined ‘High-Quality’ Diet Lowers Risk of All-Cause Mortality: PURE – TCTMD (free)
Guideline: Intestinal Failure in Adults
31 Aug, 2018 | 01:41h | UTCIntestinal failure in adults: Recommendations from the ESPEN expert groups – Clinical Nutrition (free)
Source: Critical Care Reviews Newsletter
Review: Imaging in Trauma in Limited-Resource Settings
31 Aug, 2018 | 01:42h | UTCSource: Critical Care Reviews Newsletter
Systematic Review: Antibiotics for Prolonged Wet Cough in Children
31 Aug, 2018 | 01:40h | UTCAntibiotics for prolonged wet cough in children – Cochrane Library (link to abstract and plain language summary – $ for full-text)
Commentary: Antibiotics for pediatric chronic wet cough: Cochrane review – Univadis (free registration required)
Study: Combination Immunotherapy for Melanoma Brain Metastases
31 Aug, 2018 | 01:40h | UTCCombined Nivolumab and Ipilimumab in Melanoma Metastatic to the Brain – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: Combination immunotherapy shrinks melanoma brain metastases – University of Texas M. D. Anderson Cancer Center, via ScienceDaily (free) AND Immunotherapy Drugs Slow Skin Cancer That Has Spread to the Brain – The New York Times (free)
Report: Examining Special Nutritional Requirements in Disease States
31 Aug, 2018 | 01:38h | UTC
Perspective: Adolescents’ Use of “Pod Mod” E-Cigarettes — Urgent Concerns
23 Aug, 2018 | 23:51h | UTCAdolescents’ Use of “Pod Mod” E-Cigarettes — Urgent Concerns – New England Journal of Medicine (free)
NICE Draft Guidance: Antibiotics Should Not Be Issued as First Line of Treatment for a Cough
23 Aug, 2018 | 23:52h | UTCCommentaries: Promote honey rather than antibiotics for coughs, doctors told – The Guardian (free) AND Use honey first for a cough, new guidelines say – BBC (free)
Related: Honey for acute cough in children – Cochrane Library (free systematic review and commentary)
Study: Alcohol Use and Burden for 195 Countries and Territories
23 Aug, 2018 | 23:53h | UTCCommentaries: No level of alcohol consumption improves health – The Lancet (free) AND No amount of alcohol is good for your overall health, global study says – CNN (free) AND New scientific study: no safe level of alcohol – Institute for Health Metrics and Evaluation (free)
“Alcohol was responsible for nearly 3 million deaths in 2016, the study says. It was the leading risk factor for disease and premature death in men and women between the ages of 15 and 49 worldwide in 2016, accounting for nearly one in 10 deaths.” (from @cnni see Tweet)
Viewpoint: The Challenge of Reforming Nutritional Epidemiologic Research
23 Aug, 2018 | 23:48h | UTCThe Challenge of Reforming Nutritional Epidemiologic Research – JAMA (free for a limited period)
“…the emerging picture of nutritional epidemiology is difficult to reconcile with good scientific principles. The field needs radical reform.”


