All Posts
Deprescribing Recommendations: An Essential Consideration for Clinical Guideline Developers
28 Sep, 2018 | 01:11h | UTCRelated: Position Statement: Reducing Inappropriate Medication Use & Polypharmacy (several articles and commentaries on the subject)
““Clinical guidelines often do not accommodate frailty or patients with multiple comorbid conditions. This can give rise to complex medication regimens and risk of medication harm.” Paper discusses the need to include deprescribing in clinical guidelines” (via @Deprescribing see Tweet)
Opinion: No More First Authors, no More Last Authors
28 Sep, 2018 | 01:09h | UTCNo more first authors, no more last authors – Nature (free)
“The controversial suggestion that we “blow up” authorship conventions to foster team, collaborative science” (via @EricTopol see Tweet)
Perspective: No One Knows Exactly What Would Happen If Mosquitoes Were to Disappear
28 Sep, 2018 | 01:08h | UTCNo One Knows Exactly What Would Happen If Mosquitoes Were to Disappear – The Atlantic (free)
Related: Mosquitoes Genetically Modified To Crash Species That Spreads Malaria – NPR (free) AND Scientists use gene drive to eradicate lab mosquitoes for the first time – STAT (free) AND Malaria mosquitoes wiped out in lab trials of gene drive technique – Reuters (free)
Scientific Advocacy and Biases of the Ideological and Industry Kinds
28 Sep, 2018 | 01:07h | UTCScientific Advocacy and Biases of the Ideological and Industry Kinds – Absolutely Maybe Blog (free)
Study: Ethanol Locks in Catheters for Dialysis May Prevent Sepsis
28 Sep, 2018 | 01:08h | UTCEthanol lock is effective on reducing the incidence of tunneled catheter-related bloodstream infections in hemodialysis patients: a systematic review and meta-analysis – International Urology and Nephrology (link to abstract – $ for full-text)
Commentary: Ethanol locks in catheters for dialysis may prevent sepsis – NIHR Signal (free)
Migrant and Refugee Populations: A Public Health and Policy Perspective on a Continuing Global Crisis
28 Sep, 2018 | 01:05h | UTCMigrant and refugee populations: a public health and policy perspective on a continuing global crisis – Antimicrobial Resistance & Infection Control (free) (via @equitylist)
AHA Guideline: Cardiovascular Health in Turner Syndrome
28 Sep, 2018 | 01:05h | UTCCommentary: Cardiovascular Health in Turner Syndrome – No Small Task (free)
Top Ten Things to Know: Cardiovascular Health in Turner Syndrome (free PDF)
The Global Burden of Sepsis: Barriers and Potential Solutions
28 Sep, 2018 | 01:06h | UTCThe global burden of sepsis: barriers and potential solutions – Critical Care (free)
Randomized Trial: Laparoscopic Lavage vs. Resection as Treatment for Perforated Diverticulitis
28 Sep, 2018 | 01:03h | UTCCommentary: Comparing Laparoscopic Lavage vs Resection for Perforated Diverticulitis – Medscape (free registration required)
Randomized Trial: Vaccine Against TB May Help Individuals with Latent Infection
28 Sep, 2018 | 01:04h | UTCEditorial: New Promise for Vaccines against Tuberculosis (free)
Commentaries: New TB vaccine protects half of people with latent infection – NBC Health News (free) AND Experimental vaccine shows promise in preventing TB – MedicalXpress (free)
Systematic Review of Observational Studies: Could Aspirin Play a Role in Treating Some Cancers?
28 Sep, 2018 | 01:04h | UTCCommentaries: Aspirin could play key role in treating some cancers – UPI (free) AND Could aspirin play role in treatment of cancer? – Cardiff University (free)
Study: Temporal Trends in Muscular Fitness of 10-year-olds 1998–2014
28 Sep, 2018 | 01:02h | UTCTemporal trends in muscular fitness of English 10-year-olds 1998–2014: An allometric approach – Journal of Science and Medicine in Sport (link to abstract – $ for full-text)
Commentary: Fall in strength and fitness of 10-year-olds, study shows – BBC (free) AND Ten-Year-Olds Are Weaker Today Than They Were 16 Years Ago – HuffPost (free) AND British study reveals fall in muscle strength of 10-year-olds – The Guardian (free)
Opinion: STAT’s Cheerleading Coverage of Prescription Fish Oil Capsule Lacks Crucial Context
28 Sep, 2018 | 01:01h | UTCOriginal Commentary: Amarin fish oil capsule shows dramatic benefit for cardiovascular patients, potentially upending market – STAT (free)
Randomized Trial: Insomnia Symptoms Iimprove with Online Insomnia Program
28 Sep, 2018 | 00:59h | UTCEffect of Digital Cognitive Behavioral Therapy for Insomnia on Health, Psychological Well-being, and Sleep-Related Quality of Life: A Randomized Clinical Trial – JAMA Psychiatry (free for a limited period) (via @EricTopol)
Commentary: Insomnia symptoms, overall health improve with online insomnia program – Northwestern University (free)
Study: Conventional Autopsy vs. Minimally Invasive Autopsy with Postmortem MRI, CT, and CT-guided Biopsy
28 Sep, 2018 | 01:00h | UTCConventional Autopsy versus Minimally Invasive Autopsy with Postmortem MRI, CT, and CT-guided Biopsy: Comparison of Diagnostic Performance – Radiology (free for a limited period) (via @EricTopol)
Commentary: Minimally invasive autopsy improves postmortem diagnoses – Radiology Society of North America (free)
Related Systematic Review: Non-invasive or minimally invasive autopsy compared to conventional autopsy of suspected natural deaths in adults – European Radiology (free)
Study: Association Between Physician Medical School Ranking and Patient Outcomes and Costs of Care
28 Sep, 2018 | 00:58h | UTC“Overall, little or no relation was found between the USNWR ranking of the medical school from which a physician graduated and subsequent patient mortality or readmission rates.”
Systematic Review: Modifying the Consistency of Food and Fluids for Swallowing Difficulties in Dementia
28 Sep, 2018 | 00:57h | UTCModifying the consistency of food and fluids for swallowing difficulties in dementia – Cochrane Library (free for a limited period)
Summary: Modifying the consistency of food and fluids for swallowing difficulties in dementia (free)
“We are uncertain about the immediate and long-term effects of modifying the consistency of fluid for swallowing difficulties in dementia”
Randomized Trial: Antibiotic Therapy Alone Seems Reasonable for Uncomplicated Appendicitis
28 Sep, 2018 | 00:55h | UTCFive-Year Follow-up of Antibiotic Therapy for Uncomplicated Acute Appendicitis in the APPAC Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
Podcast: Treating Appendicitis Without Surgery – 5-Year Follow-up from a Randomized Clinical Trial of Antibiotic Treatment (free)
Video Summary: Five-Year Follow-up of Patients Given Antibiotic Therapy for Uncomplicated Acute Appendicitis (free)
Commentaries: Pills for appendicitis? Surgery often not needed, study says – STAT (free) AND Antibiotics Alone Seem Reasonable for Uncomplicated Appendicitis in Adults – Physician’s First Watch (free) AND Appendicitis? Antibiotics May Be All You Need – The New York Times (10 articles per month are free)
Related: Randomized clinical trial of antibiotic therapy for uncomplicated appendicitis (link to abstract and commentaries) AND Antibiotics Versus Surgical Therapy for Uncomplicated Appendicitis (link to abstract and commentaries) AND Antibiotic Therapy versus Appendectomy for Acute Uncomplicated Appendicitis (free study and commentaries) AND New appendicitis guideline incorporates the possibility of non-operative treatment for uncomplicated disease (free guideline)
Meta-Analysis of Observational Studies: Healthy Diets May Help in Depression Prevention
28 Sep, 2018 | 00:56h | UTCHealthy dietary indices and risk of depressive outcomes: a systematic review and meta-analysis of observational studies – Molecular Psychiatry (link to abstract – $ for full-text)
Commentaries: Plant-rich diets may help prevent depression – new evidence – The Conversation (free) AND Eating a Mediterranean diet ‘may lower your risk of depression’ – NHS Choices (free) AND Expert reaction to observational studies on diet and depression – Science Media Centre (free) AND Mediterranean diet could prevent depression, new study finds – CNN (free)
“The current evidence is not sufficient to prove plant-rich diets can prevent depression as most of the evidence so far simply shows that those with poorer mental health eat worse, so it may be that those more prone to depression also choose less health” (from CNN)
Study: Recovery of Walking after Complete Spinal Cord Injury
27 Sep, 2018 | 23:06h | UTCCommentaries: Technology and therapy help individuals with chronic spinal cord injuries take steps – University of Louisville (free) AND Epidural Stimulation Helps Patients Walk After Total Paralysis – MedPage Today (free registration required) AND Paralyzed Patients Able to Walk Following Epidural Stimulation, Intense Rehab – Physician’s First Watch (free)
Study: Deep Learning Algorithm for Detection of Malignant Pulmonary Nodules on Chest Radiographs
27 Sep, 2018 | 23:04h | UTCDevelopment and Validation of Deep Learning–based Automatic Detection Algorithm for Malignant Pulmonary Nodules on Chest Radiographs – Radiology (link to abstract – $ for full-text)
Commentary: Deep learning algorithm detects malignant pulmonary nodules better than radiologists – Radiology Business (free)
Related Studies: Deep Learning for the Diagnosis of Fibrotic Lung Disease (link to abstract and commentaries) AND Can Artificial Intelligence Reliably Report Chest X-Rays? (free study and commentaries) AND Artificial Intelligence Can Determine Lung Cancer Type (link to abstract and commentaries)
ADA Guideline: Type 1 Diabetes in Children and Adolescents
28 Sep, 2018 | 00:54h | UTC
Study: Drug–herb and Drug–supplement Interactions in Older Adults
27 Sep, 2018 | 23:05h | UTCCommentaries: New study finds concurrent use of prescription drugs and dietary supplements could pose health risks – University of Hertfordshire (free) AND Concerns raised about older adults mixing prescription drugs and herbal remedies – NHS Choices (free)
Measuring Human Capital: A Systematic Analysis of 195 Countries and Territories, 1990–2016
27 Sep, 2018 | 23:03h | UTCCommentary: Unprecedented study finds nations failing to invest in education and health care at risk of slow economic growth – Institute for Health Metrics and Evaluation (free)
Infographic: What is human capital and why is it relevant? – Institute for Health Metrics and Evaluation (free)
“The first-ever study ranking countries by human capital has been published in @TheLancet. This novel approach looks at nations’ investments in health and education and their relation to GDP growth” (via @IHME_UW see Tweet)
Review: Pharmacokinetics–Pharmacodynamics Issues Relevant for the Clinical use of Beta-lactams in Critically Ill Patients
27 Sep, 2018 | 23:02h | UTCRelated: Extended Antibiotic Infusions Could Save Lives: Here’s How to Do It (free commentary) AND Mortality lower with prolonged vs. short-term IV infusion of antipseudomonal beta-lactams (link to abstract and free commentary)