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NICE Antimicrobial Prescribing Guidelines

2 Nov, 2018 | 03:51h | UTC

Antimicrobial prescribing guidelines – National Institute for Health and Care Excellence (free resources)

Just Published Guidelines: Urinary tract infection (lower): antimicrobial prescribing (free) AND Urinary tract infection (recurrent): antimicrobial prescribing (free) AND Pyelonephritis (acute): antimicrobial prescribing (free) AND Prostatitis (acute): antimicrobial prescribing (free)

See also: Summary of antimicrobial prescribing guidance – managing common infections – National Institute for Health and Care Excellence (free PDF)

 


A Brief History of Evolving Diagnostics and Therapy for Gonorrhea

5 Nov, 2018 | 11:42h | UTC

A Brief History of Evolving Diagnostics and Therapy for Gonorrhea: Lessons Learned – Clinical Infectious Diseases (free)

 


Randomized Trial: Minimally Invasive versus Abdominal Radical Hysterectomy for Cervical Cancer

2 Nov, 2018 | 03:50h | UTC

Minimally Invasive versus Abdominal Radical Hysterectomy for Cervical Cancer – New England Journal of Medicine (free)

Related Study: Survival after Minimally Invasive Radical Hysterectomy for Early-Stage Cervical Cancer – New England Journal of Medicine (free)

Editorial: Surgery in Cervical Cancer – New England Journal of Medicine (free)

Commentaries: Studies Warn Against Minimally Invasive Surgery for Cervical Cancer – The New York Times (10 articles per month are free) AND More deaths seen for less invasive cervical cancer surgery – STAT (free) AND For Cervical Cancer Patients, Less Invasive Surgery Is Worse For Survival – NPR (free)

 


Review: Hypoglycemia After Gastric Bypass Surgery

2 Nov, 2018 | 03:46h | UTC

Hypoglycemia After Gastric Bypass Surgery: Current Concepts and Controversies – The Journal of Clinical Endocrinology & Metabolism (free)

 


Meta-Analysis: Association of Sodium Intake and Major Cardiovascular Outcomes

2 Nov, 2018 | 03:49h | UTC

Association of sodium intake and major cardiovascular outcomes: a dose-response meta-analysis of prospective cohort studies – BMC Cardiovascular Disorders (free)

Related: Effects of Sodium and Potassium Intake on Chronic Disease Outcomes and Risks (free report and summary) AND Urinary Sodium Excretion, Blood Pressure, Cardiovascular Disease, and Mortality (link to abstract and commentaries) AND Salt intake and Cardiovascular Disease (free report and commentary)

 


Report: Cell Phone Radio Frequency Radiation and Risk of Cancer

2 Nov, 2018 | 03:48h | UTC

Cell Phone Radio Frequency Radiation – National Toxicology Program (free)

Commentaries: High exposure to radio frequency radiation associated with cancer in male rats – NIH News Releases (free) AND Expert reaction to study on mobile phones and rats – Science Media Centre (free) AND Study of Cellphone Risks Finds ‘Some Evidence’ of Link to Cancer, at Least in Male Rats – The New York Times (10 articles per month are free)

 


Guidelines for the Safe Practice of Total Intravenous Anesthesia

2 Nov, 2018 | 03:47h | UTC

Guidelines for the safe practice of total intravenous anaesthesia (TIVA) – Anaesthesia (free)

 


Randomized Trial: Mirtazapine Added to SSRIs or SNRIs for Treatment Resistant Depression

2 Nov, 2018 | 03:43h | UTC

Mirtazapine added to SSRIs or SNRIs for treatment resistant depression in primary care: phase III randomised placebo controlled trial (MIR) – The BMJ (free)

Commentary: Popular drug combination for treatment resistant depression is not more effective than a single antidepressant in primary care – University of Bristol (free)

 


Perspective: Current and Future Landscape of Nutritional Epidemiologic Research

2 Nov, 2018 | 03:41h | UTC

Current and Future Landscape of Nutritional Epidemiologic Research – JAMA (free for a limited period)

 


The Emperor’s New Clothes: A Critical Appraisal of Evidence-based Medicine

2 Nov, 2018 | 03:44h | UTC

The Emperor’s New Clothes: a Critical Appraisal of Evidence-based Medicine – International Journal of Medical Sciences (free)

 


Guideline: Pediatric Readiness in the Emergency Department

2 Nov, 2018 | 03:42h | UTC

Pediatric Readiness in the Emergency Department – Pediatrics (free)

News Release: Groups update joint guidance on pediatric emergency care (free)

 


Myocarditis in Adults: ED Presentations, Evaluation, and Management

2 Nov, 2018 | 03:40h | UTC

Myocarditis in Adults: ED Presentations, Evaluation, and Management – emDocs (free)

 


Review: Side Effects of Long‐Term Proton Pump Inhibitor Use

2 Nov, 2018 | 03:40h | UTC

Side Effects of Long‐Term Proton Pump Inhibitor Use: A Review – Basic & Clinical Pharmacology & Toxicology (free)

 


Systematic Review: Prophylactic Antibiotic Therapy for COPD

2 Nov, 2018 | 03:36h | UTC

Prophylactic antibiotic therapy for chronic obstructive pulmonary disease (COPD) – Cochrane Library (free)

Summary: Preventative antibiotic therapy for people with COPD – Cochrane Library (free)

“Use of continuous and intermittent prophylactic antibiotics results in a clinically significant benefit in reducing exacerbations in COPD patients.”

 


Cohort Study: BMI of 21-25kg/m2 Linked to Lowest Risk of Dying

2 Nov, 2018 | 03:38h | UTC

Association of BMI with overall and cause-specific mortality: a population-based cohort study of 3·6 million adults in the UK – The Lancet Diabetes & Endocrinology (free)

Commentaries: The association between BMI and mortality: implications for obesity prevention – The Lancet Diabetes & Endocrinology (free) AND BMI of 21-25kg/m2 linked to lowest risk of dying from cancer and heart disease – London School of Hygiene & Tropical Medicine (free) AND Being too fat or too thin ‘can cost four years of life’ – BBC (free)

 


Review: Management of Cancer-Therapy-Induced LV Dysfunction

2 Nov, 2018 | 03:34h | UTC

Management of Cancer-Therapy-Induced LV Dysfunction: Can the Guidelines Help? – American College of Cardiology (free) (via @md_arianemacedo)

Related: Cardio-Onco-Hematology in Clinical Practice (series of reviews and guidelines on the subject)

 


Systematic Review: Effectiveness of Plant-Based Diets in the Management of Type 2 Diabetes

2 Nov, 2018 | 03:37h | UTC

Effectiveness of plant-based diets in promoting well-being in the management of type 2 diabetes: a systematic review – BMJ Open Diabetes Research & Care (free)

Commentaries: Expert reaction to study looking at plant based or vegan diets and type 2 diabetes – Science Media Centre (free) AND Vegan diet linked to better diabetes control and wellbeing – OnMedica (free)

 


Study: Targeted Neurotechnology Restores Walking in Humans with Spinal Cord Injury

2 Nov, 2018 | 03:35h | UTC

Targeted neurotechnology restores walking in humans with spinal cord injury – Nature (free)

Editorial: Paralysed people walk again after spinal-cord stimulation (free)

Commentaries: Spinal implant helps three paralysed men walk again – BBC (free) AND Once Paralyzed, Three Men Take Steps Again With Spinal Implant – The New York Times (10 articles per month are free)

 


Payment Designed for People: Introducing the Primary Care Outcomes Model

2 Nov, 2018 | 03:32h | UTC

Payment Designed for People: Introducing the Primary Care Outcomes Model – NEJM Catalyst (free)

 


Study: Antibiotic and Acid-Suppression Medications During Early Childhood are Associated with Obesity

2 Nov, 2018 | 03:32h | UTC

Antibiotic and acid-suppression medications during early childhood are associated with obesity – Gut (free)

Related Study: Early Antibiotic Exposure and Weight Outcomes in Young Children – Pediatrics (free)

Commentaries: Expert reaction to antibiotic and antacid use in early childhood and risk of obesity – Science Media Centre (free) AND Antibiotic Exposure in Early Life Tied to Slightly Higher Obesity Risk – NEJM Journal Watch (free) AND Antibiotics, H2RAs and PPIs linked to child obesity – OnMedica (free) AND Two studies tie early antibiotic exposure to increased obesity risk – CIDRAP (free)

 


Study: Short Interpregnancy Intervals are Associated with Increased Risks for Adverse Pregnancy Outcomes

2 Nov, 2018 | 03:31h | UTC

Association of Short Interpregnancy Interval With Pregnancy Outcomes According to Maternal Age – JAMA Internal Medicine (free for a limited period)

Commentaries: Balancing the Risks and Desires for Pregnancy in Older Mothers: Increasing Morbidity, Declining Fertility – JAMA Internal Medicine (free for a limited period) AND Women ‘should leave at least a year between pregnancies’ – NHS Choices (free) AND Waiting a year between pregnancies lowers health risks, study says – CNN (free) AND Study: Do Even Older Moms Have To Wait 18 Months Between Pregnancies? – CommonHealth (free)

 


Study: Financial Conflicts of Interest Among Authors of Clinical Guidelines

2 Nov, 2018 | 03:28h | UTC

Prevalence of Financial Conflicts of Interest Among Authors of Clinical Guidelines Related to High-Revenue Medications – JAMA Internal Medicine (link to abstract – $ for full-text)

Commentaries: More Than Half of Physician Guideline Authors for Expensive Medications Have Undeclared Conflicts of Interest – MedicalResearch.com (free) AND Many Clinical Guideline Authors Have Undeclared Payments – Medical Health News (free)

 


Perspective: Unpublished Medical Research ‘a threat to public health’

2 Nov, 2018 | 03:23h | UTC

Unpublished medical research ‘a threat to public health’ – BBC (free)

 


Meta-Analysis: Cannabinoids for the Treatment of Chronic Noncancer Pain Conditions

2 Nov, 2018 | 03:29h | UTC

Cannabis and cannabinoids for the treatment of people with chronic noncancer pain conditions: a systematic review and meta-analysis of controlled and observational studies – Pain (free)

“It seems unlikely that cannabinoids are highly effective medicines for chronic noncancer pain conditions.”

 


Guidelines for Blunt Cerebrovascular Injury

2 Nov, 2018 | 03:21h | UTC

Best practice guidelines for blunt cerebrovascular injury (BCVI) – Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine (free)

 


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