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Meta-analysis: Fluoroquinolones and the Risk of Aortopathy
30 Nov, 2018 | 03:06h | UTC“…current fluoroquinolone use was significantly associated with increased risk of aortic aneurysm and dissection.”
Perspective: We’re Living Longer … But A Medical Journal Sees Many Causes For Alarm
30 Nov, 2018 | 03:02h | UTCWe’re Living Longer … But A Medical Journal Sees Many Causes For Alarm – NPR (free)
Related Editorial: GBD 2017: a fragile world – The Lancet (free)
Ebola Outbreak News – Democratic Republic of the Congo
30 Nov, 2018 | 03:02h | UTCDisease Outbreak News: Ebola virus disease – Democratic Republic of the Congo – World Health Organization (free)
Commentaries: DRC’s 426-case Ebola outbreak now 2nd largest ever – CIDRAP (free) AND Ebola and War in the Democratic Republic of Congo: Avoiding Failure and Thinking Ahead – JAMA (free) AND Ramping Up the Response to Ebola – New England Journal of Medicine (free) AND Ebola outbreak in east Congo now world’s second biggest – Reuters (free)
Meta-Analysis: Incidental Findings on MRI of Apparently Asymptomatic Adults
30 Nov, 2018 | 02:58h | UTCCommentary: Many incidental findings spotted on MRIs, few turn out to be cancer – Reuters (free)
Related: Prevalence and outcomes of incidental imaging findings: umbrella review (free)
Randomized Trial: Low-Dose Imipramine for Refractory Functional Dyspepsia
30 Nov, 2018 | 02:57h | UTCLow-dose imipramine for refractory functional dyspepsia: a randomised, double-blind, placebo-controlled trial – The Lancet Gastroenterology & Hepatology (link to abstract – $ for full-text)
Commentary: Low-Dose Imipramine Alternative Treatment for Refractory Functional Dyspepsia – Clinical Advisor (free)
Study: Cardiovascular Toxicities Associated with Immune Checkpoint Inhibitors
30 Nov, 2018 | 02:56h | UTCCardiovascular toxicities associated with immune checkpoint inhibitors: an observational, retrospective, pharmacovigilance study – The Lancet Oncology (link to abstract – $ for full-text)
Commentary: Cardiovascular Toxicities Associated With Immune Checkpoint Inhibitor Treatment – The ASCO Post (free)
Related Guidelines: Management of Immune-Related Adverse Events in Patients Treated With Immune Checkpoint Inhibitor Therapy: American Society of Clinical Oncology Clinical Practice Guideline (free) AND Managing toxicities associated with immune checkpoint inhibitors: consensus recommendations from the Society for Immunotherapy of Cancer (SITC) Toxicity Management Working Group (free)
Related Review: New drugs, new toxicities: severe side effects of modern targeted and immunotherapy of cancer and their management – Critical Care (free)
Guideline: Diagnosis and Management of Polycythaemia Vera
30 Nov, 2018 | 02:51h | UTC
New ASH Clinical Practice Guidelines on Venous Thromboembolism
30 Nov, 2018 | 02:53h | UTCASH Clinical Practice Guidelines on Venous Thromboembolism – American Society of Hematology (free)
News Release: New clinical practice guidelines for venous thromboembolism (free)
Systematic Review: Prolonged Thromboprophylaxis for Abdominal or Pelvic Surgery
30 Nov, 2018 | 02:48h | UTCProlonged thromboprophylaxis with low molecular weight heparin for abdominal or pelvic surgery – Cochrane Library (free)
ACP Position Statement: Principles for Patient and Family Partnership in Care
30 Nov, 2018 | 02:52h | UTCNews Release: American College of Physicians releases principles to guide patient partnership in health care (free)
Randomized Trial: Alirocumab and Cardiovascular Outcomes after Acute Coronary Syndrome
30 Nov, 2018 | 02:49h | UTCAlirocumab and Cardiovascular Outcomes after Acute Coronary Syndrome – New England Journal of Medicine (link to abstract – $ for full-text)
Video Summary: Alirocumab and CV Events after Acute Coronary Syndrome (free)
Study: Youngest in Class More Likely to be Diagnosed with ADHD
30 Nov, 2018 | 02:50h | UTCAttention Deficit–Hyperactivity Disorder and Month of School Enrollment – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: When starting school, younger children are more likely to be diagnosed with ADHD – Harvard Medical School (free) AND Youngest Children In A Class Are Most Likely To Get ADHD Diagnosis – NPR (free) AND Younger school entry could set stage for ADHD diagnosis – Associated Press (free)
Related: Systematic Review: Youngest in Class More Likely to be Diagnosed with ADHD (free study and commentaries)
Perspective: Is Our Constant Use of Digital Technologies Affecting our Brain Health?
30 Nov, 2018 | 02:46h | UTCIs our constant use of digital technologies affecting our brain health? We asked 11 experts – VOX (free)
Global Burden of Pneumonia in Children Younger than 5 Years
30 Nov, 2018 | 02:44h | UTCInvited Commentary: Global childhood pneumonia: the good news, the bad news, and the way ahead (free)
Europe’s Bold Open-Access Plan Detailed
30 Nov, 2018 | 02:47h | UTCPlan S: From Principles to Implementation. cOAlition S Releases Implementation Guidance on Plan S (free)
Commentary: Funders flesh out details of Europe’s bold open-access plan (free)
Related: In Win for Open Access, Two Major Funders Won’t Cover Publishing in Hybrid Journals (free commentaries) AND cOAlition S: Making Open Access a Reality by 2020 (free Statement and commentaries)
WHO Housing and Health Guidelines
30 Nov, 2018 | 02:45h | UTCWHO Housing and health guidelines – World Health Organization (free)
Survey Snapshot: What Would Accelerate the Adoption of Value-Based Care?
30 Nov, 2018 | 02:36h | UTCSurvey Snapshot: What Would Accelerate the Adoption of Value-Based Care? – NEJM Catalyst (free)
Study: Screenning for Colorectal Cancer with FOBT Only Effective in Men
30 Nov, 2018 | 02:41h | UTCCommentaries: Screening for colorectal cancer spares male patients from intense treatments – University of Helsinki (free) AND FOBT Colorectal Cancer Screening Only Effective in Men – Medscape (free registration required)
Global Burden of Alzheimer’s Disease and Other Dementias
30 Nov, 2018 | 02:43h | UTCInvited Commentary: Statistics on the burden of dementia: need for stronger data – The Lancet (free)
“In 2016, globally, 43·8 million individuals lived with dementia, increased from 20.2 million in 1990; dementia was the fifth leading cause of death globally (2·4 million) and more women than men had dementia” (via @TheLancet see Tweet with infographic)
Review: Therapy and Management of Pneumocystis Jirovecii
30 Nov, 2018 | 02:39h | UTCTherapy and Management of Pneumocystis jirovecii – Infection – Journal of Fungi (free)
This article belongs to the Special Issue Treatments for Fungal Infections (free reviews)
Review: Arterial Thrombosis in Unusual Sites
30 Nov, 2018 | 02:38h | UTCArterial thrombosis in unusual sites: A practical review – European Journal of Haematology (free)
Study: Some Research May be Encouraging Ineffective Prescriptions
30 Nov, 2018 | 02:32h | UTCAssessment of Pregabalin Postapproval Trials and the Suggestion of Efficacy for New Indications: A Systematic Review – JAMA Internal Medicine (link to abstract – $ for full-text)
Commentary: Some research may be encouraging ineffective prescriptions, says new study – McGill University (free)
“Our point is not to condemn these individual trials. Instead, we are saying that—when you zoom out and look at what’s happening at the level of the forest—the trees begin to look less healthy.” (from McGill University)
Viewpoint: A Global Public Health Victory for Tobacco Plain-Packaging Laws in Australia
30 Nov, 2018 | 02:29h | UTCA Global Public Health Victory for Tobacco Plain-Packaging Laws in Australia – JAMA Internal Medicine (free for a limited period)
Ten Simple Rules for Collaboratively Writing a Multi-Authored Paper
30 Nov, 2018 | 02:35h | UTCTen simple rules for collaboratively writing a multi-authored paper – PLOS Computational Biology (free) (via @Abraham_RMI)
Genome-Edited Baby Provokes International Outcry
30 Nov, 2018 | 02:02h | UTCGenome-edited baby claim provokes international outcry – Nature (free)
See also: A Reckless and Needless Use of Gene-Editing on Human Embryos – The Atlantic (free) AND Chinese researcher claims first gene-edited babies – Associated Press (free) AND EXCLUSIVE: Chinese scientists are creating CRISPR babies – MIT Technology Review (free) AND Expert reaction to reports of the first genome edited baby – Science Media Centre (free) AND What we know — and what we don’t — about the claim of world’s first gene-edited babies – STAT (free)