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Alex Nowbar’s weekly research reviews – 22 January 2019
23 Jan, 2019 | 00:20h | UTCAlex Nowbar’s weekly research reviews, 22 January 2019 – The BMJ Opinion (free)
Alex Nowbar reviews the latest research from the top medical journals.
Meta-Analysis: Association of Aspirin Use for Primary Prevention with Cardiovascular Events and Bleeding Events
22 Jan, 2019 | 22:18h | UTCAssociation of Aspirin Use for Primary Prevention With Cardiovascular Events and Bleeding Events: A Systematic Review and Meta-analysis – JAMA (link to abstract – $ for full-text)
Commentaries: Expert reaction to study looking at aspirin use in healthy people, and cardiovascular events and bleeding – Science Media Centre (free) AND Aspirin Modest at Best in Primary CV Prevention – MedPage Today (free registration required) AND When to take (or not take) aspirin to prevent heart trouble – CNN (free)
Related: Meta-Analysis: Efficacy and Safety of Aspirin for Primary Prevention of Cardiovascular Events (link to abstract and commentaries) AND Aspirin Did Not Prevent Deaths or Disability in Healthy Older Adults (free study and commentaries)
DRC Ebola Total Hits 699 Amid More Resistance, Insecurity
22 Jan, 2019 | 22:42h | UTCDRC Ebola total hits 699 amid more resistance, insecurity – CIDRAP (free)
Related: The Ebola outbreak in Eastern Congo is moving toward a major city. That’s not good. – Vox (free) AND Where are the Ebola diagnostics from last time? – Nature (free)
Canadian Clinical Practice Guideline for the Management of Irritable Bowel Syndrome (IBS)
22 Jan, 2019 | 18:02h | UTCRelated Guidelines: Clinical Practice Guidelines for Irritable Bowel Syndrome in Korea, 2017 (free) AND American College of Gastroenterology Monograph on Management of Irritable Bowel Syndrome (free) AND Evidence-based clinical practice guidelines for irritable bowel syndrome – Journal of Gastroenterology (free) AND Irritable bowel syndrome in adults: diagnosis and management – National Institute for Health and Care Excellence (NICE) (free)
New IASP Classification of Chronic Pain for the International Classification of Diseases (ICD-11)
22 Jan, 2019 | 00:29h | UTCCommentary: IASP Updates Classification of Chronic Pain – Clinical Advisor (free)
Related Commentary on Twitter
Chronic pain as a symptom or a disease: the IASP Classification of Chronic Pain for the International Classification of Diseases (ICD-11) #PainJournal https://t.co/Riegvjag5N pic.twitter.com/9hquW4dDa1
— PAIN Journal (@PAINthejournal) January 16, 2019
Obstructive Sleep Apnea in Cardiovascular Disease: A Review of the Literature and Proposed Multidisciplinary Clinical Management Strategy
22 Jan, 2019 | 12:40h | UTCRelated Reviews: Sleep Apnea and Cardiovascular Disease: Lessons from Recent Trials and Need for Team Science – Circulation (free) AND Sleep Apnea: Types, Mechanisms, and Clinical Cardiovascular Consequences – Journal of the American College of Cardiology (free)
Study: Patient Organizations and Conflicts of Interest
22 Jan, 2019 | 00:28h | UTCEditorial: Patient organizations and conflict of interest (free)
Commentaries: Jeremy Taylor: Financial interests of patient organisations – The BMJ Opinion (free) AND Financial interests common in patient reps on NICE appraisal – OnMedica (free)
Related Opinion: Why Big Pharma Must Disclose Payments to Patient Groups (free)
Perspective: Doing Things for No Reason in the Hospital
22 Jan, 2019 | 00:27h | UTCDoing things for no reason in the hospital – The BMJ Opinion (free)
“Many of the things we do as doctors continue simply because “that’s the way we’ve always done it,” says Abraar Karan”
NYT Editorial: How to Inoculate Against Anti-Vaxxers
21 Jan, 2019 | 23:58h | UTCHow to Inoculate Against Anti-Vaxxers – The New York Times (10 articles per month are free)
Related: WHO: Ten Threats to Global Health in 2019 (free statement) AND Measles Outbreaks Show Why Anti Vaxxers Made WHO’s 10 Global Health Threats – Forbes (free)
“Opioids Don’t Work for Most People with Chronic Pain. So Why do We Still Prescribe Them?”
22 Jan, 2019 | 00:26h | UTCRelated study: Meta-Analysis: Opioids for Chronic Noncancer Pain (link to abstract and commentaries)
See also: Opioid Wisely – Choosing Wisely Canada (free) AND Guideline for opioid therapy and chronic noncancer pain – Canadian Medical Association Journal (free)
Podcast: Sickle Cell Disease, Management & Complications
22 Jan, 2019 | 00:11h | UTC#136 Sickle Cell Disease, Management & Complications – The Curbsiders Internal Medicine Podcast (free)
Weaning Failure of Cardiovascular Origin: How to Suspect, Detect and Treat
21 Jan, 2019 | 23:38h | UTC
Study: Blood Test May Detect Presymptomatic Alzheimer’s Disease
21 Jan, 2019 | 22:39h | UTCCommentaries: Blood test detects Alzheimer’s damage before symptoms – Washington University in St. Louis (free) AND Early prediction of Alzheimer’s progression: Blood protein – DZNE – German Center for Neurodegenerative Diseases (free) AND Blood test could detect Alzheimer’s more than 10 years earlier – study – The Guardian (free)
Related: Elevated Brain Amyloid and Subsequent Cognitive Decline Among Cognitively Normal Persons (link to abstract and commentaries) AND Identifying incipient dementia individuals using machine learning and amyloid imaging (free study and commentaries) AND High performance plasma amyloid-β biomarkers for Alzheimer’s disease (link to abstract and commentaries) AND Amyloid PET Scan for Predicting Alzheimer’s Disease in Mild Cognitive Impairment (free study and commentaries) AND Retinal Nerve Fiber Layer Thinning and Future Cognitive Decline (link to abstract and commentaries) AND Artificial Intelligence may Predict Alzheimer’s Years Before Diagnosis (link to abstract and commentaries)
Study: Duration of Electrocardiographic Monitoring of Emergency Department Patients with Syncope
21 Jan, 2019 | 22:53h | UTCDuration of Electrocardiographic Monitoring of Emergency Department Patients with Syncope – Circulation (link to abstract – $ for full-text)
Commentaries: How long do people need to be monitored after fainting? Study reveals best ways to catch life-threatening conditions – The Ottawa Hospital (free) AND 2 hours in the ER enough to rule out risky arrhythmias in most syncope patients – Cardiovascular Business (free)
Systematic Review: Gonadotrophins for Ovulation Induction in Women with Polycystic Ovary Syndrome
21 Jan, 2019 | 16:08h | UTCGonadotrophins for ovulation induction in women with polycystic ovary syndrome – Cochrane Library (free)
Summary: Gonadotrophins to induce ovulation in women with polycystic ovary syndrome (PCOS) – Cochrane Library (free)
Related Commentary on Twitter
Latest @Cochranecgf Review compares the #effectiveness and #safety of #gonadotrophins for #ovulation induction in women with #PCOS who do not ovulate or conceive on #clomiphene citrate #blogshot #CochraneEvidence #Cochrane https://t.co/5yQmxM3YLN pic.twitter.com/aga0GilvSr
— The Cochrane Library (@CochraneLibrary) January 20, 2019
Systematic Review: Laparoscopic Entry Techniques
21 Jan, 2019 | 15:00h | UTCLaparoscopic entry techniques – Cochrane Library (free)
Summary: Laparoscopic entry techniques – Cochrane Library (free)
Overview of Cochrane Reviews: Rehabilitation for People with Multiple Sclerosis
21 Jan, 2019 | 14:55h | UTCRehabilitation for people with multiple sclerosis: an overview of Cochrane Reviews – Cochrane Library (free)
Summary: Rehabilitation for persons with multiple sclerosis – Cochrane Library (free)
Systematic Review: C‐reactive Protein for Diagnosing Late‐onset Infection in Newborn Infants
21 Jan, 2019 | 15:22h | UTCC‐reactive protein for diagnosing late‐onset infection in newborn infants – Cochrane Library (free)
Summary: C-reaction protein for diagnosing infection in newborn infants – Cochrane Library (free)
Related Commentary on Twitter
Serum CRP level not accurate enough to inform diagnosis or treatment of late-onset infection in newborns: https://t.co/Amn0zRuNUW @BAPM_Official @AmerAcadPeds @AAPneonatal @NIHR_DC @EBNEO @RCPCHtweets @Blisscharity @crd_york @JveWagner @JemmaCleminson pic.twitter.com/JBCjs6egzY
— The Cochrane Library (@CochraneLibrary) January 21, 2019
New Single-Dose Drug to Prevent Relapse of Plasmodium vivax Malaria
21 Jan, 2019 | 14:18h | UTCSingle-Dose Tafenoquine to Prevent Relapse of Plasmodium vivax Malaria – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: New one-dose drug prevents malaria relapse, studies show – CIDRAP (free)
New Concepts in Diagnostics for Invasive Mycoses: Non-Culture-Based Methodologies
21 Jan, 2019 | 14:28h | UTCNew Concepts in Diagnostics for Invasive Mycoses: Non-Culture-Based Methodologies – Journal of Fungi (free PDF)
This article belongs to the Special Issue Fungal Infections in Immunocompromised Hosts (free articles)
Review: Interstitial Lung Disease Associated with Systemic Sclerosis
21 Jan, 2019 | 14:12h | UTCInterstitial lung disease associated with systemic sclerosis (SSc-ILD) – Respiratory Research (free)
Exercise-induced Hypoalgesia: A Meta-analysis of Exercise Dosing for the Treatment of Chronic Pain
21 Jan, 2019 | 12:37h | UTC
Meta-Analysis: Interventions for Obesity Among Schoolchildren
21 Jan, 2019 | 12:29h | UTCInterventions for obesity among schoolchildren: A systematic review and meta-analyses – PLOS One (free)
WHO: Global Antimicrobial Resistance Surveillance System (GLASS) Report
21 Jan, 2019 | 10:20h | UTC
Patient Engagement Survey: Health Care Has a Lot to Learn from Consumer-Friendly Industries
21 Jan, 2019 | 10:15h | UTC