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FDA: Stop SGLT2 Inhibitors Before Scheduled Surgery
20 Mar, 2020 | 10:52h | UTCCommentary: FDA advises stopping SGLT2 inhibitor treatment prior to surgery – The Hospitalist (free)
“- Canagliflozin, dapagliflozin, and empagliflozin should each be discontinued at least three days before scheduled surgery.
– Ertugliflozin should be discontinued at least four days before scheduled surgery.
– Blood glucose levels should be carefully monitored after discontinuation of the SGLT2 inhibitor and appropriately managed before surgery.”
Cohort Study: Associations of Fat and Carbohydrate Intake with Cardiovascular Disease and Mortality
20 Mar, 2020 | 10:48h | UTC
Video: Coronavirus Update with Anthony Fauci, MD
19 Mar, 2020 | 11:04h | UTCCoronavirus Update with Anthony Fauci, MD – March 18, 2020 – JAMA (free)
Study: SARS-CoV-2 Infection in Children
19 Mar, 2020 | 10:59h | UTCSARS-CoV-2 Infection in Children – New England Journal of Medicine (free)
Related Articles: Epidemiological Characteristics of 2143 Pediatric Patients With 2019 Coronavirus Disease in China – Peditrics (free) Detection of Covid-19 in Children in Early January 2020 in Wuhan, China – New England Journal of Medicine (free) AND Coronavirus Infections in Children Including COVID-19: An Overview of the Epidemiology, Clinical Features, Diagnosis, Treatment and Prevention Options in Children – The Pediatric Infectious Diseases Journal (free PDF) AND Characteristics of pediatric SARS-CoV-2 infection and potential evidence for persistent fecal viral shedding – Nature Medicine (free)
[Abstract Only] Randomized Trial: Surgery vs. Conservative Care for Persistent Sciatica Lasting 4 to 12 Months
19 Mar, 2020 | 11:03h | UTCSurgery versus Conservative Care for Persistent Sciatica Lasting 4 to 12 Months – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: What Works Best to Ease the Pain of Sciatica? – HealthDay News (free)
Randomized Trial: No Benefit from Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19
19 Mar, 2020 | 11:01h | UTCEditorial: Covid-19 — The Search for Effective Therapy (free)
See also: Interview with Dr. Eric Rubin and Dr. Lindsey Baden on new research on possible treatments for Covid-19 – New England Journal of Medicine (free)
Study: Diarrhea is a Prominent Symptom of COVID-19
19 Mar, 2020 | 10:56h | UTCCommentaries: Study from The American Journal of Gastroenterology Reveals Diarrhea is a Prominent Symptom of COVID-19 – American College of Gastroenterology (free) AND Diarrhea a key symptom in 1 of 4 COVID-19 patients, study finds – UPI (free)
Podcast: New Research on Possible Treatments for Covid-19
19 Mar, 2020 | 10:57h | UTC
Perspective: Confirmatory Trial for Drug to Prevent Preterm Birth Finds No Benefit, So Why Is It Still Prescribed?
19 Mar, 2020 | 10:52h | UTCConfirmatory Trial for Drug to Prevent Preterm Birth Finds No Benefit, So Why Is It Still Prescribed? – JAMA (free for a limited period)
Original Article: Randomized Trial: Injectable 17-α-hydroxyprogesterone Not Effective for the Prevention of Recurrent Preterm Birth (free study and commentaries)
Related Study: A Randomized Trial of Progesterone in Women with Recurrent Miscarriages – New England Journal of Medicine (free)
State of the Art Review: Management of ANCA Associated Vasculitis
19 Mar, 2020 | 10:54h | UTCManagement of ANCA associated vasculitis – The BMJ (free)
ACC: Catheterization Laboratory Considerations During the Coronavirus (COVID-19) Pandemic
19 Mar, 2020 | 10:46h | UTCCommentary: COVID-19 Poised to Upend the Cath Lab, ACC and SCAI Say – TCTMD (free)
Randomized Trial: Robotic Inguinal vs. Transabdominal Laparoscopic Inguinal Hernia Repair
19 Mar, 2020 | 10:50h | UTCRobotic Inguinal vs Transabdominal Laparoscopic Inguinal Hernia Repair: The RIVAL Randomized Clinical Trial – JAMA Surgery (free for a limited period)
Invited Commentary: Robotics vs Laparoscopy—Are They Truly Rivals? – JAMA Surgery (free for a limited period)
Author Interview: Robotic Approach vs Traditional Laparoscopic Approach and Postoperative Outcomes (free)
Calculating the Sample Size Required for Developing a Clinical Prediction Model
19 Mar, 2020 | 10:42h | UTCCalculating the sample size required for developing a clinical prediction model – The BMJ (free)
Coronaviruses and the Cardiovascular System: Acute and Long-term Implications
19 Mar, 2020 | 10:43h | UTC
Meta-Analysis: Psychotherapy for Depression Across Different Age Groups
19 Mar, 2020 | 10:41h | UTCEditorial: The Age of Depression and Its Treatments (free)
Commentary: Psychotherapy not as effective for kids, adolescents with depression, study says – UPI (free)
Report: 2020 Alzheimer’s Disease Facts and Figures
18 Mar, 2020 | 09:54h | UTC2020 Alzheimer’s disease facts and figures – Alzheimer’s & Dementia (free)
Report: Impact of Non-pharmaceutical Interventions to Reduce COVID19 Mortality and Healthcare Demand
18 Mar, 2020 | 09:53h | UTCSummary: Report 9 – Imperial College London (free)
Commentaries: US, UK coronavirus strategies shifted following UK epidemiologists’ ominous report – CNN (free) AND New Analysis Suggests Months Of Social Distancing May Be Needed To Stop Virus – NPR (free)
“…in an unmitigated epidemic, we would predict approximately 510,000 deaths in GB and 2.2 million in the US, not accounting for the potential negative effects of health systems being overwhelmed on mortality.”
KDOQI Clinical Practice Guideline for Vascular Access
18 Mar, 2020 | 09:56h | UTC
Study: Aerosol and Surface Stability of SARS-CoV-2
18 Mar, 2020 | 09:50h | UTCCommentaries: New coronavirus stable for hours on surfaces – NIH News Releases (free) AND How Long Will Coronavirus Live on Surfaces or in the Air Around You? – The New York Times (10 articles per month are free) AND New coronavirus can persist in air for hours and on surfaces for days: study – Reuters (free)
Randomized, Phase 2 Trial: Safety and Immunogenicity of a Tetravalent Dengue Vaccine in Children Aged 2–17 Years
18 Mar, 2020 | 09:47h | UTCSafety and immunogenicity of a tetravalent dengue vaccine in children aged 2–17 years: a randomised, placebo-controlled, phase 2 trial – The Lancet (link to abstract – $ for full-text)
[Abstract Only] Study: Consequences of Measles Undervaccination
18 Mar, 2020 | 09:49h | UTCConsequences of Undervaccination – Measles Outbreak, New York City, 2018-2019 – New England Journal of Medicine (link to abstract – $ for full-text)
Cohort Study: Proton Pump Inhibitors Linked to Small Increased Risk of Fracture in Children
18 Mar, 2020 | 09:46h | UTCAssociation Between Proton Pump Inhibitor Use and Risk of Fracture in Children – JAMA Pediatrics (free for a limited period)
Commentary: Proton-Pump Inhibitors: Small Increased Risk of Fractures in Children – MedicalResearch.com (free)
[Abstract Only] Study: Machine Learning for Early Prediction of Circulatory Failure in the Intensive Care Unit
18 Mar, 2020 | 09:43h | UTCEarly prediction of circulatory failure in the intensive care unit using machine learning – Nature Medicine (link to abstract – $ for full-text)
Commentary: Circulatory failure is predictable – ETH Zurich (free)
Radiology Department Preparedness for COVID-19: Radiology Scientific Expert Panel
17 Mar, 2020 | 08:47h | UTCRadiology Department Preparedness for COVID-19: Radiology Scientific Expert Panel – Radiology (free)
Commentary: Experts stress radiology preparedness for COVID-19 – Radiology Society of North America (free)
Study: Using Artificial Intelligence to Analyze CT Scans may Better Predict Cardiovascular Risk than Established Clinical Parameters
18 Mar, 2020 | 09:45h | UTCCommentaries: Artificial intelligence-derived imaging biomarkers to improve population health – The Lancet Digital Health (free) AND Artificial Intelligence Predicts Heart Disease Risk from CT Scans – NIH Research Matters (free)