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[Abstract Only] Study: A Single Negative Screening Colonoscopy is Associated with Reduced Colorectal Cancer Incidence for up to 17.4 years

1 Jun, 2020 | 03:36h | UTC

Long-Term Colorectal Cancer Incidence and Mortality After a Single Negative Screening Colonoscopy – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentary: A single negative colonoscopy associated with long-lasting and significantly reduced cancer incidence – American College of Physicians

 


[Abstract Only] #ASCO20 – Randomized Trial: Enzalutamide and Survival in Nonmetastatic, Castration-Resistant Prostate Cancer

1 Jun, 2020 | 03:33h | UTC

Enzalutamide and Survival in Nonmetastatic, Castration-Resistant Prostate Cancer – New England Journal of Medicine

 


Editorial: Shielding from Covid-19 Should be Stratified by Risk

29 May, 2020 | 03:34h | UTC

Shielding from covid-19 should be stratified by risk – The BMJ

 


[Abstract Only] Meta-Analysis: Reappraisal of the Treatment Duration of Antibiotic Regimens for Acute Uncomplicated Cystitis in Adult Women

1 Jun, 2020 | 03:31h | UTC

Reappraisal of the treatment duration of antibiotic regimens for acute uncomplicated cystitis in adult women: a systematic review and network meta-analysis of 61 randomised clinical trials – The Lancet Infectious Diseases (link to abstract – $ for full-text)

 

Related Commentary on Twitter

 


Cohort Study: Clinical Characteristics, Etiology, and Initial Management Strategy of Newly Diagnosed Periprosthetic Joint Infection

1 Jun, 2020 | 03:29h | UTC

Clinical Characteristics, Etiology, and Initial Management Strategy of Newly Diagnosed Periprosthetic Joint Infection: A Multicenter, Prospective Observational Cohort Study of 783 Patients – Open Forum Infectious Diseases

 


Study in a Cruise Boat Showed 81% of Patients Infected with Covid-19 were Asymptomatic

29 May, 2020 | 03:31h | UTC

COVID-19: in the footsteps of Ernest Shackleton – Thorax

Commentaries: New Paper Finds Startling Number Of Asymptomatic Covid-19 Carriers – Forbes AND Asymptomatic COVID-19 cases may be more common than suspected – NBC News AND Cruise ship study hints at many ‘silent’ COVID-19 infections – The BMJ

 


Opinion: Using Controlled Trials to Resolve Key Unknowns About Policy During the COVID-19 Pandemic

29 May, 2020 | 03:27h | UTC

Using Controlled Trials to Resolve Key Unknowns About Policy During the COVID-19 Pandemic – JAMA

 


Conducting Clinical Research During the COVID-19 Pandemic: Protecting Scientific Integrity

29 May, 2020 | 03:26h | UTC

Conducting Clinical Research During the COVID-19 Pandemic: Protecting Scientific Integrity – JAMA

 


42% of Patients with Covid-19 Asymptomatic in Study from China

29 May, 2020 | 03:29h | UTC

Comparison of Clinical Characteristics of Patients with Asymptomatic vs Symptomatic Coronavirus Disease 2019 in Wuhan, China – JAMA Network Open

Commentaries: 40% of COVID-19 patients may be asymptomatic as disease progresses – UPI AND How Common Are Asymptomatic Cases of COVID-19? – U.S News

 


Perspective: For Seniors, COVID-19 Sets Off A Pandemic Of Despair

29 May, 2020 | 03:23h | UTC

For Seniors, COVID-19 Sets Off A Pandemic Of Despair – Kaiser Health News

 


Wastewater Testing Gains Traction as a Covid-19 Early Warning System

29 May, 2020 | 03:22h | UTC

Wastewater testing gains traction as a Covid-19 early warning system – STAT

Related: SARS-CoV-2 RNA in wastewater anticipated COVID-19 occurrence in a low prevalence area – Water Research AND New Research Examines Wastewater to Detect Community Spread of Covid-19

 


Observational Study: Many Patients with Covid-19 in the ICU Develop Thromboembolism Despite Routine Prophylaxis

29 May, 2020 | 03:17h | UTC

Routine Venous Thromboembolism Prophylaxis May Be Inadequate in the Hypercoagulable State of Severe Coronavirus Disease 2019 – Critical Care Medicine

 


Opinion: Ethical Guidelines for Deliberately Infecting Volunteers with COVID-19 to Speed Vaccine Development

29 May, 2020 | 03:19h | UTC

Ethical guidelines for deliberately infecting volunteers with COVID-19 – Journal of Medical Ethics

Commentary: COVID-19 vaccine development: New guidelines for ethical approach to infecting trial volunteers – University of Warwick

Related: Challenge trials can speed development of a Covid-19 vaccine. Planning for them needs to start now – STAT AND AstraZeneca says it may consider exposing vaccine trial participants to virus – Reuters

 


Ethical Guidelines for COVID-19 Tracing Apps

29 May, 2020 | 03:18h | UTC

Ethical guidelines for COVID-19 tracing apps – Nature

 


Small Study Shows No Evidence of Secondary Transmission of COVID-19 from Children Attending School

29 May, 2020 | 03:14h | UTC

No evidence of secondary transmission of COVID-19 from children attending school in Ireland, 2020 – Eurosurveillance

 


Randomized Trial: Gastrointestinal Complications After Pancreatoduodenectomy With Epidural vs. Patient-Controlled Intravenous Analgesia

29 May, 2020 | 03:05h | UTC

Gastrointestinal Complications After Pancreatoduodenectomy With Epidural vs Patient-Controlled Intravenous Analgesia: A Randomized Clinical Trial – JAMA Surgery

 

Related Commentary on Twitter

https://twitter.com/rosa_klotz/status/1265766559773065222

 


Study: Face Mask Use in Households May Reduce Secondary Transmission of SARS-CoV-2

29 May, 2020 | 03:15h | UTC

Reduction of secondary transmission of SARS-CoV-2 in households by face mask use, disinfection and social distancing: a cohort study in Beijing, China – The BMJ Global Health

Commentaries: Wearing face masks at home might help ward off COVID-19 spread among family members – BMJ AND Expert reaction to study looking at face masks in the home – Science Media Centre

 


International Consensus on the Diagnosis and Management of Dumping Syndrome

29 May, 2020 | 03:12h | UTC

International consensus on the diagnosis and management of dumping syndrome – Nature Reviews Endocrinology

 


[Abstract Only] Meta-Analysis: Postoperative Continuation of Antibiotic Prophylaxis Does Not Reduce the Incidence of Surgical Site Infections

29 May, 2020 | 03:09h | UTC

Effect of postoperative continuation of antibiotic prophylaxis on the incidence of surgical site infection: a systematic review and meta-analysis – The Lancet Infectious Diseases

 


A Deep Learning Algorithm to Detect Chronic Kidney Disease from Retinal Photographs

29 May, 2020 | 03:02h | UTC

A deep learning algorithm to detect chronic kidney disease from retinal photographs in community-based populations – The Lancet Digital Health

Commentary: Opportunistic deep learning of retinal photographs: the window to the body revisited – The Lancet Digital Health

 

Related Commentary on Twitter

 


[Abstract Only] Study: Repeat ANA Testing After a Negative Result has Low Utility and Results in High Cost

29 May, 2020 | 03:01h | UTC

Utility of repeated antinuclear antibody tests: a retrospective database study – The Lancet Rheumatology

 


Medicines with One Seller and Many Buyers: Strategies to Increase the Power of the Payer

29 May, 2020 | 03:00h | UTC

Medicines with one seller and many buyers: strategies to increase the power of the payer – The BMJ

 


Meta-Analysis: Direct Oral Anticoagulants vs. Low‐molecular‐weight Heparin for the Treatment of Cancer‐associated Thrombosis

29 May, 2020 | 03:03h | UTC

Direct oral anticoagulants compared to low‐molecular‐weight heparin for the treatment of cancer‐associated thrombosis: Updated systematic review and meta‐analysis of randomized controlled trials – Research and Practice in Thrombosis and Haemostasis

“In patients with cancer‐associated VTE, DOACs are more effective in preventing recurrent VTE compared to LMWH. However, risk of bleeding is increased with DOACs, especially in patients with GI cancer.”

 


WHO Interim Guidance: Clinical Management of COVID-19

28 May, 2020 | 10:02h | UTC

Clinical management of COVID-19 – World Health Organization

 


Face Coverings for the Public: Laying Straw Men to Rest, by Trisha Greenhalgh

28 May, 2020 | 09:57h | UTC

Face coverings for the public: Laying straw men to rest – Journal of Evaluation in Clinical Practice

Related: Face coverings for the lay public: an alternative view – CEBM Oxford AND Cloth Masks May Prevent Transmission of COVID-19: An Evidence-Based, Risk-Based Approach – Annals of Internal Medicine

 

https://twitter.com/EricTopol/status/1265640531016552449

 


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