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Opinion: The Moral Imperative to Include Pregnant Women in Clinical Trials of Interventions for COVID-19

2 Jul, 2020 | 08:46h | UTC

The Moral Imperative to Include Pregnant Women in Clinical Trials of Interventions for COVID-19 – Annals of Internal Medicine

Related: Excluding pregnancy from COVID-19 trials: Protection from harm or the harm of protection? – Canadian Medical Association Journal

 


Evidence Does Not Support Vitamin D for Reducing Respiratory Infections, Reviews Conclude

2 Jul, 2020 | 08:42h | UTC

Evidence does not support vitamin D for reducing respiratory infections, reviews conclude – The BMJ

 


The Ethics of COVID-19 Treatment Studies: Too Many are Open, Too Few are Double-masked

2 Jul, 2020 | 08:43h | UTC

The ethics of COVID-19 treatment studies: too many are open, too few are double-masked – CEBM Oxford

 


Randomized Trial of Amoxicillin vs. Placebo for Pneumonia in Children from Low-Income Communities

2 Jul, 2020 | 08:40h | UTC

Randomized Trial of Amoxicillin for Pneumonia in Pakistan – New England Journal of Medicine

 


Randomized Trial: Amoxicillin for 3 Days Noninferior to Amoxicillin for 5 Days for Chest-Indrawing Pneumonia in Children

2 Jul, 2020 | 08:41h | UTC

Amoxicillin for 3 or 5 Days for Chest-Indrawing Pneumonia in Malawian Children – New England Journal of Medicine

Visual Abstract: Amoxicillin for 3 or 5 Days for Chest-Indrawing Pneumonia

Commentaries: Antibiotic use, duration questioned for kids’ pneumonia in low-resource areas – CIDRAP AND Three-day amoxicillin course effective for chest-indrawing pneumonia in Malawi children – 2 Minute Medicine

 


Microhematuria: AUA/SUFU Guideline

2 Jul, 2020 | 08:38h | UTC

Microhematuria: AUA/SUFU Guideline – American Urological Association

News Release: Leading Organizations Release Joint Clinical Guideline For Diagnosis And Evaluation Of Microhematuria – American Urological Association

 


[Abstract Only] Randomized Trial: Triple Inhaled Therapy at Two Glucocorticoid Doses in Moderate-to-Very-Severe COPD

2 Jul, 2020 | 08:39h | UTC

Triple Inhaled Therapy at Two Glucocorticoid Doses in Moderate-to-Very-Severe COPD – New England Journal of Medicine

Commentaries: Triple Therapy at 2 Doses Appears to Reduce COPD Exacerbations, Study Says – AJMC AND Triple Inhaled Therapy Aids in Moderate-to-Very Severe COPD – Physician’s Weekly

 


Update of the Treatment of Nosocomial Pneumonia in the ICU

2 Jul, 2020 | 08:37h | UTC

Update of the treatment of nosocomial pneumonia in the ICU – Critical Care

 


Meta-Analysis: Electronically Delivered vs. Face to Face Cognitive Behavioral Therapies in Depressive Disorders

2 Jul, 2020 | 08:35h | UTC

A comparison of electronically-delivered and face to face cognitive behavioural therapies in depressive disorders: A systematic review and meta-analysis – EClinicalMedicine

 


Global Variation in the Prevalence of Suicidal Ideation, Anxiety and their Correlates Among Adolescents

2 Jul, 2020 | 08:33h | UTC

Global variation in the prevalence of suicidal ideation, anxiety and their correlates among adolescents: A population based study of 82 countries – EclinicalMedicine

 


[Abstract Only] Randomized Trial: Early Vaginal Progesterone in Twin Pregnancies Does Not Prevent Spontaneous Preterm Birth

2 Jul, 2020 | 08:36h | UTC

Early vaginal progesterone versus Placebo in Twin Pregnancies for prevention of spontaneous preterm birth (EVENTS): A randomised double-blind trial – American Journal of Obstetrics & Gynecology (link to abstract – $ for full-text)

Related Studies: Randomized Trial: Progesterone in Women with Bleeding in Early Pregnancy (link to study and commentaries) AND Randomized Trial: Injectable 17-α-hydroxyprogesterone Not Effective for the Prevention of Recurrent Preterm Birth (link to study and commentaries)

 


Editorial: Is a “Cytokine Storm” Relevant to COVID-19?

1 Jul, 2020 | 07:59h | UTC

Is a “Cytokine Storm” Relevant to COVID-19? – JAMA Internal Medicine

 

Related Commentary on Twitter

 


Editorial: Will COVID-19 be Evidence-based Medicine’s Nemesis?

1 Jul, 2020 | 07:58h | UTC

Will COVID-19 be evidence-based medicine’s nemesis? – PLOS Medicine

“In the current fast-moving pandemic, where the cost of inaction is counted in the grim mortality figures announced daily, implementing new policy interventions in the absence of randomized trial evidence has become both a scientific and moral imperative.”

 

Related Commentary on Twitter

https://twitter.com/trishgreenhalgh/status/1278069554640543747

 


Systematic Review: Systemic Defenses to Prevent Intravenous Medication Errors in Hospitals

2 Jul, 2020 | 08:32h | UTC

Systemic Defenses to Prevent Intravenous Medication Errors in Hospitals: A Systematic Review – Journal of Patient Safety

Commentary: Systemic defenses to prevent intravenous medication errors in hospitals: a systematic review – PSNet

 


The Line is Forming for a COVID-19 Vaccine. Who Should be at the Front?

1 Jul, 2020 | 07:49h | UTC

The line is forming for a COVID-19 vaccine. Who should be at the front? – Science

 


Whole-town Study Reveals More than 40% of COVID-19 Infections Had no Symptoms

1 Jul, 2020 | 07:56h | UTC

Whole-town study reveals more than 40% of COVID-19 infections had no symptoms – Imperial College London

Original Study: Suppression of a SARS-CoV-2 outbreak in the Italian municipality of Vo’ – Nature

 


Meta-Analysis: Outcomes from Intensive Care in Patients with COVID‐19

1 Jul, 2020 | 07:46h | UTC

Outcomes from intensive care in patients with COVID‐19: a systematic review and meta‐analysis of observational studies – Anaesthesia

 


Why COVID-19 Silent Hypoxemia is Baffling to Physicians

1 Jul, 2020 | 07:48h | UTC

Why COVID-19 Silent Hypoxemia is Baffling to Physicians – American Journal of Respiratory and Critical Care Medicine

Commentary: Silent Hypoxemia from COVID-19 Explained – Journal Feed

 


AAP COVID-19 Planning Considerations: Guidance for School Re-entry

1 Jul, 2020 | 07:45h | UTC

COVID-19 Planning Considerations: Guidance for School Re-entry – American Academy of Pediatrics

Commentaries: U.S. Pediatricians Call For In-Person School This Fall – NPR AND Academic, mental and physical benefits of in-person school outweigh virus risks, pediatrics group says – CNN AND Why a Pediatric Group Is Pushing to Reopen Schools This Fall – The New York Times

 


Swine Flu Strain with Human Pandemic Potential Increasingly Found in Pigs in China

1 Jul, 2020 | 07:40h | UTC

Swine flu strain with human pandemic potential increasingly found in pigs in China – Science

Original Study: Prevalent Eurasian avian-like H1N1 swine influenza virus with 2009 pandemic viral genes facilitating human infection – Proceedings of the National Academy of Sciences

See also: ‘Pandemic potential’: New flu virus is found in Chinese pigs – World Economic Forum AND New Swine Flu Virus In China Has ‘Pandemic Potential,’ Here Are 7 Reasons Why – Forbes AND A new swine-flu strain with ‘pandemic potential’ was just found circulating in Chinese pigs – Business Insider

 


Editorial: Twin Epidemics of Covid-19 and Non-communicable Disease

1 Jul, 2020 | 07:42h | UTC

Twin epidemics of covid-19 and non-communicable disease – The BMJ

 


Meta-Analysis: No Survival Benefit with Routine Revascularization in Stable Ischemic Heart Disease

1 Jul, 2020 | 07:38h | UTC

Routine Revascularization versus Initial Medical Therapy for Stable Ischemic Heart Disease: A Systematic Review and Meta-Analysis of Randomized Trials – Circulation

Commentary: No Survival Benefit With Revascularization in Stable CAD, Meta-analysis Confirms – TCTMD

 

Related Commentary on Twitter

 


Meta-Analysis: Digital Mammography Does Not Improve Outcomes in Population Screening when Compared to Film Mammography

1 Jul, 2020 | 07:37h | UTC

Impact of Full-Field Digital Mammography versus Film-Screen Mammography in Population Screening: a Meta-analysis – JNCI: Journal of the National Cancer Institute

Commentaries: Digital breast cancer detection technology does not improve outcomes – Oxford University Press USA AND How Beneficial Is Digital Mammography? – MedicalResearch.com AND Meta-Analysis: Digital Mammography No Better Than Film – MedPage Today (free registration required)

 


Food is Medicine: Actions to Integrate Food and Nutrition into Healthcare

1 Jul, 2020 | 07:34h | UTC

Food is medicine: actions to integrate food and nutrition into healthcare – The BMJ

 

Related Commentary on Twitter

 


Guideline Summary: Major Consensus Statement on IV Contrast Nephropathy

1 Jul, 2020 | 07:33h | UTC

Major Consensus Statement on IV Contrast Nephropathy – Journal Feed

Original Guideline: ACR/NKF Consensus Statement: “The Risk of Acute Kidney Injury Developing in Patients with Reduced Kidney Function Following Exposure to Intravenous Iodinated Contrast Media has Been Overstated” (Guideline and commentaries)

 


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