All Posts
RCT | Targeted hypoglossal nerve stimulation may benefit patients with obstructive sleep apnea
11 Apr, 2023 | 14:07h | UTC
Commentary on Twitter
In this study, proximal targeted hypoglossal nerve responses proved safe and effective in treating sleep apnea and improving sleep architecture and quality of life, while comparing favorably with those in distal hypoglossal nerve stimulation trials. https://t.co/yorNGW9uoi
— JAMA Otolaryngology – Head & Neck Surgery (@JAMAOto) April 6, 2023
Single-arm study | Effects of CAR-T therapy in children with relapsed or refractory high-risk neuroblastoma
11 Apr, 2023 | 14:09h | UTCGD2-CART01 for Relapsed or Refractory High-Risk Neuroblastoma – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: CAR-T Therapy Helps Kids Battling Deadly Nervous System Tumors – HealthDay
Commentary on Twitter
Patients with neuroblastoma received CAR-positive T cells targeting a disialoganglioside. Of 63% with a response, 33% had a complete response (some durable). Cytokine release syndrome was common. https://t.co/LDaIoeGfV7
Read the science behind the study: https://t.co/L4D5x1G6BF pic.twitter.com/VfsQKfSVFf
— NEJM (@NEJM) April 5, 2023
M-A | Noninvasive respiratory support after extubation
11 Apr, 2023 | 14:03h | UTC
Review | Pulmonary arterial hypertension in pregnancy
11 Apr, 2023 | 14:06h | UTCPulmonary arterial hypertension in pregnancy – Current Opinion in Cardiology
Preliminary study suggests a PEG-coated hemostatic patch reduces pancreatic fistula post-pancreatoduodenectomy
11 Apr, 2023 | 14:02h | UTC
Commentary on Twitter
POPF prevention ? any help from haemostatic patches?!
? Polyethylene glycol-coated haemostatic patch for prevention: RCT from ??
? POPF reduction 90% (!!!) regardless of other risk factors
? What is your practice?! https://t.co/Fn7OgFgwTR pic.twitter.com/ZjlxuUTZEN
— Giovanni Marchegiani (@Gio_Marchegiani) April 7, 2023
Review | Evaluation and management of chronic thromboembolic pulmonary hypertension
11 Apr, 2023 | 14:00h | UTCEvaluation and Management of Chronic Thromboembolic Pulmonary Hypertension – Chest
M-A | The risk of long-term cardiometabolic disease in women with premature or early menopause
11 Apr, 2023 | 13:59h | UTC
RCT | Augmented ablation fails to outperform standard ablation in paroxysmal AF patients
11 Apr, 2023 | 13:57h | UTCStandard vs Augmented Ablation of Paroxysmal Atrial Fibrillation for Reduction of Atrial Fibrillation Recurrence: The AWARE Randomized Clinical Trial – JAMA Cardiology (link to abstract – $ for full-text)
Commentary: Augmented Ablation Adds No Benefit in Prevention of Recurrent Atrial Arrhythmia – HCP Live
Commentary on Twitter
The AWARE Trial tested an augmented WACA in pts with paroxysmal AF. A high single procedure freedom from AF was noted without an improvement compared to single WACA. There might be a “ceiling effect” to catheter ablation in patients with paroxysmal AF. https://t.co/2ihyHwHlTA pic.twitter.com/waSbp0QF1a
— JAMA Cardiology (@JAMACardio) March 22, 2023
Study identifies top 3 anticancer drugs with highest atrial fibrillation rates
11 Apr, 2023 | 13:55h | UTCCommentary: More AF Surveillance Needed in Chemotherapy Trials, Meta-analysis Hints – TCTMD
WHO Report | Dengue & Chikungunya cases spreading beyond known transmission zones in the Americas
10 Apr, 2023 | 14:04h | UTCCommentary: WHO: Concerning Spread of Dengue, Chikungunya in Latin America – JAMA
M-A | Benefits and harms of drug treatment for type 2 diabetes
10 Apr, 2023 | 14:03h | UTC
Umbrella review unveils benefits of cutting free sugars to 6 teaspoons/day
10 Apr, 2023 | 14:00h | UTCDietary sugar consumption and health: umbrella review – The BMJ
News Release: Limit added sugar to six teaspoons a day to improve health, urge experts – BMJ Newsroom
Brief Review | Ten tips on fever in the ICU
10 Apr, 2023 | 14:02h | UTCTen tips on fever – Intensive Care Medicine
Cohort Study | Antiphospholipid antibodies’ prevalence & link to cardiovascular events
10 Apr, 2023 | 13:59h | UTCNews Release: Antiphospholipid antibodies may increase heart disease risk in healthy people – Michigan Medicine
RCT | Maternal RSVpreF vaccination protects infants from severe RSV illness
10 Apr, 2023 | 13:56h | UTCBivalent Prefusion F Vaccine in Pregnancy to Prevent RSV Illness in Infants – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Vaccination during pregnancy could prevent RSV illness in infants – Charité – Universitätsmedizin Berlin
Commentary on Twitter
In a phase 3 trial, adults (≥60 years of age) received one 120-μg dose of RSVpreF vaccine or placebo. Vaccine efficacy against RSV-associated lower respiratory tract illness was 67 to 86%. https://t.co/R9u77iWjF9 pic.twitter.com/iPU8VAMQ9M
— NEJM (@NEJM) April 5, 2023
RCT | RSVpreF vaccine successfully prevents RSV-associated respiratory illness in seniors
10 Apr, 2023 | 13:54h | UTCEfficacy and Safety of a Bivalent RSV Prefusion F Vaccine in Older Adults – New England Journal of Medicine (link to abstract – $ for full-text)
AHA/ASA Scientific Statement | The neurovasculome: key roles in brain health and cognitive impairment
10 Apr, 2023 | 13:53h | UTCTop Things to Know: The Neurovasculome: Roles in brain health and cognitive impairment – American Heart Association
News Release: Blood vessels – not just brain cells – can affect brain health, new report finds – American Heart Association
Commentary: The Brain Vasculome. What Is It and What Does It Do? – American Heart Association
Commentary on Twitter
The Neurovasculome: Key Roles in Brain Health and Cognitive Impairment: A Scientific Statement From the American Heart Association/American Stroke Association @American_Heart @American_Stroke @AHAScience @VCI_EricSmith @SusanneVanVeluwhttps://t.co/SrXuZS7tep pic.twitter.com/WRRR3kVQVQ
— Stroke AHA/ASA (@StrokeAHA_ASA) April 3, 2023
AAP Clinical Report | Health supervision for children and adolescents with Marfan syndrome
10 Apr, 2023 | 13:51h | UTCHealth Supervision for Children and Adolescents With Marfan Syndrome – Pediatrics
Commentary on Twitter
This @AmerAcadPeds clinical report is designed to assist pediatricians in recognizing the features of Marfan syndrome as well as caring for the individual with Marfan syndrome to maximize their health and quality of life: https://t.co/xo9m303yhJ #Pediatrics pic.twitter.com/L5USU0CdxJ
— AAP Pediatrics (@aap_peds) March 21, 2023
ESO expedited recommendation on tenecteplase for acute ischemic stroke
10 Apr, 2023 | 13:44h | UTCRelated:
RCT | Tenecteplase noninferior to alteplase in acute ischemic cerebrovascular events
RCT: Tenecteplase vs. alteplase for the management of acute ischemic stroke.
Randomized Controlled Trial: Tenecteplase vs Alteplase before Thrombectomy for Ischemic Stroke
Swiss recommendations for the treatment of type 2 diabetes mellitus
10 Apr, 2023 | 13:50h | UTCRelated: Guideline | ADA 2023 Standards of Medical Care in Diabetes.
Cohort Study | Long-term mortality in individuals diagnosed with cancer during pregnancy or postpartum
10 Apr, 2023 | 13:48h | UTCLong-term Mortality in Individuals Diagnosed With Cancer During Pregnancy or Postpartum – JAMA Oncology (free for a limited period)
Commentary on Twitter
Retrospective cohort study of 24,307 premenopausal women w/cancer shows higher risk of death w/pregnancy-assoc cancer than cancer remote from pregnancy, but results varied by site of cancer & in pregnancy vs. postpartum. https://t.co/7Eps4fUfLS
— JAMA Oncology (@JAMAOnc) April 7, 2023
Position Statement | Neuroprognostication in the post cardiac arrest patient
10 Apr, 2023 | 13:46h | UTC
Review | Cardiogenic shock classification and associated mortality risk
10 Apr, 2023 | 13:42h | UTCCardiogenic Shock Classification and Associated Mortality Risk – Mayo Clinic Proceedings
Perspective | ARDS complicating traumatic brain injury. Can opposite strategies converge?
10 Apr, 2023 | 13:39h | UTCAcute respiratory distress syndrome complicating traumatic brain injury. Can opposite strategies converge? – Intensive Care Medicine (free for a limited period)
Phase 2 RCT | Addition of metastasis-directed therapy to intermittent hormone therapy for oligometastatic prostate cancer
10 Apr, 2023 | 13:41h | UTCAddition of Metastasis-Directed Therapy to Intermittent Hormone Therapy for Oligometastatic Prostate Cancer: The EXTEND Phase 2 Randomized Clinical Trial – JAMA Oncology (free for a limited period)
Commentary on Twitter
Randomized trial of intermittent hormone therapy +/- radiation to oligometastatic sites of #prostatecancer shows significantly improved PFS & assoc time off hormone therapy & w/normal testosterone from combination. https://t.co/ZnmkQuqHZm #RadOnc #PCSM #GUCSM
— JAMA Oncology (@JAMAOnc) April 6, 2023