All Posts
Vertical transmission of Zika virus and its outcomes: a Bayesian synthesis of prospective studies
20 Oct, 2020 | 01:30h | UTCCommentary: Desideratum: a developmentalist view of Zika virus infection – The Lancet Infectious Diseases
Plastic surgery complications: A review for emergency clinicians
20 Oct, 2020 | 01:32h | UTC
[Abstract Only] Systematic review and meta-analysis of native kidney biopsy complications
20 Oct, 2020 | 01:26h | UTCSystematic Review and Meta-Analysis of Native Kidney Biopsy Complications – Clinical Journal of the American Society of Nephrology (link to abstract – $ for full-text)
Commentary on Twitter
A meta-analysis found that although native kidney biopsy is an invasive diagnostic procedure, the rates of bleeding complications are low. Complications are more frequently seen after kidney biopsies of hospitalized patients with AKI. https://t.co/kxK6qxX1fc pic.twitter.com/SgCoI505cc
— CJASN (@CJASN) October 15, 2020
‘No evidence of effect’ versus ‘evidence of no effect’: how do they differ?
20 Oct, 2020 | 01:28h | UTC
Commentary on Twitter
What is the difference between ‘no evidence of effect’ vs ‘evidence of no effect’? @Elpida_Vnz discusses this important concept in a @Students4BE blog: https://t.co/0CCSclr0lH “Absence of evidence is not evidence of absence”.
— Cochrane (@cochranecollab) October 16, 2020
The Lancet: Latest global disease estimates reveal perfect storm of rising chronic diseases and public health failures fuelling COVID-19 pandemic
18 Oct, 2020 | 23:21h | UTCCommentaries: Global rise in chronic diseases combined with Covid-19 bodes ill for world health – CNN AND Global study shows deadly convergence of chronic disease, COVID-19 – CIDRAP
See report: NEW Special issue of The Global Burden of Disease Study 2019
Related Editorial: Global health: time for radical change? – The Lancet
Meta-analysis: Evidence-based prevention of Alzheimer’s disease
20 Oct, 2020 | 01:21h | UTCCommentaries: Biggest risk factors identified to try and prevent Alzheimer’s disease – BMJ AND Systematic review finds ten lifestyle factors that clearly impact the probability of developing Alzheimer’s disease (AD) – Sharp Brains
Commentary on Twitter
Evidence-based #prevention of #Alzheimers disease https://t.co/XOMiEoMlmI via @JNNP_BMJ #dementia @perryd43 @PennilessScribe @u3Y4BDE @SanWren @lfkraus @the_scholar1 @ktanimara @drsharwood @TargetLatino @LilithResists @Joseph_Santoro @liftdupbyangels @mrtom101 @SteveDitchfield pic.twitter.com/T5hqbzmIwi
— Ian Kremer (@LEAD_Coalition) July 24, 2020
[Abstract Only] Meta-analysis: Effect of urate-lowering therapy on cardiovascular and kidney outcomes
20 Oct, 2020 | 01:22h | UTCEffect of Urate-Lowering Therapy on Cardiovascular and Kidney Outcomes: A Systematic Review and Meta-Analysis – Clinical Journal of the American Society of Nephrology (link to abstract – $ for full-text)
Commentary on Twitter
Study found urate-lowering therapy didn't produce benefits on clinical outcomes including major adverse cardiovascular events, all-cause mortality & kidney failure. Insufficient evidence to support urate lowering to improve kidney & cardiovascular outcomes https://t.co/uifm4vikYe pic.twitter.com/3fV60V3Lcx
— CJASN (@CJASN) October 14, 2020
[Preprint] Multi-organ impairment in low-risk individuals with long COVID
18 Oct, 2020 | 23:18h | UTCMulti-organ impairment in low-risk individuals with long COVID – medRxiv
Related study (preprint): Persistent symptoms after Covid-19: qualitative study of 114 long Covid patients and draft quality criteria for services – medRxiv
Commentary on Twitter
"In a young, low-risk population with ongoing symptoms, almost 70% of individuals have impairment in 1 or more organs 4 months after initial symptoms of #SARSCoV2 infection" #LongCovid https://t.co/gPnDtacI1J by @amibanerjee1 and colleagues
via @ahandvanish<-🙏 pic.twitter.com/7mKEsQgq5l— Eric Topol (@EricTopol) October 17, 2020
Improving prone positioning for severe ARDS during the COVID-19 pandemic: An implementation mapping approach
18 Oct, 2020 | 23:17h | UTC
Commentary on Twitter
Improving Prone Positioning for Severe ARDS during the COVID-19 Pandemic: An Implementation Mapping Approach
✅ Just Accepted
🔗 https://t.co/V8K3MUdSWU pic.twitter.com/wPJCp2mKaE— Annals of the ATS (@AnnalsATS) October 13, 2020
WHO: Herd immunity, lockdowns and COVID-19
18 Oct, 2020 | 23:19h | UTCCoronavirus disease (COVID-19): Herd immunity, lockdowns and COVID-19 – World Health Organization
Commentary on Twitter
Herd immunity is a concept used for vaccination, in which a population can be protected from a virus if a threshold of vaccination is reached. Vaccinated people are protected from getting the disease & passing it on, breaking any chains of transmission.
👉https://t.co/X9N7zcyfOX pic.twitter.com/V22iA6OqOq
— World Health Organization (WHO) (@WHO) October 16, 2020
New studies show reduced prevalence and severity of SARS-CoV-2 infection in ABO blood group O
18 Oct, 2020 | 23:16h | UTCStudy 1: Reduced prevalence of SARS-CoV-2 infection in ABO blood group O – Blood Advances
Commentaries: People with blood type O may have lower risk of Covid-19 infection and severe illness, two new studies suggest – CNN AND Studies offer new evidence for possible link between blood type and COVID-19 susceptibility – American Society of Hematology
Answering key questions about COVID-19 vaccines
18 Oct, 2020 | 23:10h | UTCAnswering Key Questions About COVID-19 Vaccines – JAMA
Commentary on Twitter
Many individuals are hesitant about receiving #COVID19 vaccines. It is critical that clinicians stay well informed about emerging data so that they can help patients make sound decisions https://t.co/1QDwOKuDqc @JesseGoodmanMD @ImmunizeOrg @pharmacists
— JAMA (@JAMA_current) October 16, 2020
NIHR dynamic review of the evidence around ongoing Covid19 symptoms (often called Long Covid)
18 Oct, 2020 | 23:14h | UTCA dynamic review of the evidence around ongoing Covid19 symptoms (often called Long Covid) – National Institute for Health Research
News Release: Living with COVID: NIHR publishes dynamic themed review into ‘ongoing COVID’
Commentaries: Coronavirus: ‘Long Covid could be four different syndromes’ – BBC AND Long covid could be four different syndromes, review suggests – The BMJ AND ‘Long COVID’ may affect multiple parts of body and mind, doctors say – Reuters
Acute Respiratory Distress Syndrome: Contemporary management and novel approaches during COVID-19
18 Oct, 2020 | 23:11h | UTCSource: Grupo UTI Clínica HCFMUSP
Commentary on Twitter
Review article in @_Anesthesiology showing a summary of 25 yr of ARDS intervention trials and contemporary management and novel approaches during COVID-19 ✅#ICU #CriticalCare #COVID__19 #ARDS https://t.co/MjLGgoTGy6 pic.twitter.com/wkVoOikhKQ
— Alice Blet, MD, PhD 🩺🔬 (@BletAlice) October 9, 2020
Postlicensure evaluation of COVID-19 Vaccines
18 Oct, 2020 | 23:08h | UTCPostlicensure Evaluation of COVID-19 Vaccines – JAMA
Randomized trial: Effectiveness of pelvic floor muscle training with and without electromyographic biofeedback for urinary incontinence in women
18 Oct, 2020 | 23:06h | UTCCommentary: For Urinary Incontinence, No Need to Add Biofeedback to Pelvic Floor Exercises – NEJM Journal Watch
Commentary on Twitter
This RCT did not find a statistically significant or clinically important difference in severity of urinary incontinence between women randomised to electromyographic biofeedback plus pelvic floor muscle training or to pelvic floor muscle training alonehttps://t.co/z8nxLplT57
— The BMJ (@bmj_latest) October 17, 2020
Cytokine elevation in severe and critical COVID-19: A rapid systematic review, meta-analysis, and comparison with other inflammatory syndromes
18 Oct, 2020 | 23:07h | UTC
Commentary on Twitter
The cytokine storm of severe #COVID19 and how it differs from ARDS, sepsis, and CAR-T cytokine release syndrome. Best review to date on this ★
Today @LancetRespirMed https://t.co/BOUjvIOWLi @danleisman @Poietic_Justice @IcahnMountSinai @CDMD62
🙏 for pulling all this together pic.twitter.com/qZCPbrxvYU— Eric Topol (@EricTopol) October 16, 2020
New PLOS pricing test could signal end of scientists paying to publish free papers
18 Oct, 2020 | 23:02h | UTCNew PLOS pricing test could signal end of scientists paying to publish free papers – Science
Randomized trial: Targeting rehabilitation to improve outcomes after total knee arthroplasty in patients at risk of poor outcomes
18 Oct, 2020 | 23:04h | UTCCommentary: Self-Directed Physical Therapy Effective After Total Knee Arthroplasty – NEJM Journal Watch
Commentaries on Twitter
Outpatient therapist led rehabilitation was not superior to a single physiotherapist review and home exercise based regimen in patients at risk of poor outcomes after total knee arthroplasty, finds new research by @df_hamiltonhttps://t.co/DOTv1q8VJ6
— The BMJ (@bmj_latest) October 13, 2020
This study suggests that targeting postoperative physiotherapy to those most in need is a feasible delivery method, but that the actual content of the rehabilitation seems to have minimal influence on patient outcomes@df_hamiltonhttps://t.co/JISOQE4pMr
— The BMJ (@bmj_latest) October 17, 2020
SCCM International consensus conference on prediction and identification of long-term impairments after critical illness
18 Oct, 2020 | 22:59h | UTCSystematic review: Prediction Models for Physical, Cognitive, and Mental Health Impairments After Critical Illness: A Systematic Review and Critical Appraisal – Critical Care Medicine
Source: Grupo UTI Clínica HCFMUSP
Commentary on Twitter
https://twitter.com/Michael_Harhay/status/1316728913368952834
[Abstract Only] Study: Comparison of amisulpride, aripiprazole, and olanzapine in patients with schizophrenia-spectrum disorders
18 Oct, 2020 | 23:00h | UTCAmisulpride, aripiprazole, and olanzapine in patients with schizophrenia-spectrum disorders (BeSt InTro): a pragmatic, rater-blind, semi-randomised trial – The Lancet Psychiatry (link to abstract – $ for full-text)
Commentary on Twitter
https://twitter.com/TheLancetPsych/status/1317014163823104000
Guideline on anesthesia and sedation in breastfeeding women
18 Oct, 2020 | 23:01h | UTCGuideline on anaesthesia and sedation in breastfeeding women 2020 – Anaesthesia
Commentary: Guidelines Indicate Breastfeeding Is Safe After Maternal Anesthesia – Physician’s Briefing
Commentary on Twitter
🔐These new @Assoc_Anaes guidelines for anaesthesia and sedation in breastfeeding women are new for 2020 and #FOAMed forever!
An excellent read for #WorldAnaesthesiaDay!@jmitchelldoc @ElaineW14626897 @BfWendy @mikekinsella10
🔗https://t.co/nMAyWjdW0G pic.twitter.com/pRKzcUaNhY
— 𝘈𝘯𝘢𝘦𝘴𝘵𝘩𝘦𝘴𝘪𝘢 (@Anaes_Journal) October 16, 2020
Guideline: Management and prevention of anemia (acute bleeding excluded) in adult critical care patients
18 Oct, 2020 | 22:52h | UTC
Commentary on Twitter
Latest guidelines for anemia 🩸in critically ill patients by @SigLasocki published in @AccpmJ
📈 what threshold?
🩸 how many RBCs?
💉EPO as a substitute?➡️check the Full 📃 for the answers !https://t.co/sJIIbunwKB#CriticalCare #ICU #Anemia #MedTwitter #AnesthTwitter https://t.co/AMD5xZnWDr
— Alice Blet, MD, PhD 🩺🔬 (@BletAlice) October 15, 2020
[Preprint] WHO SOLIDARITY trial results published; Remdesivir, Hydroxychloroquine, Lopinavir, and Interferon do not improve outcomes in Covid-19
16 Oct, 2020 | 09:42h | UTCRepurposed antiviral drugs for COVID-19; interim WHO SOLIDARITY trial results – medRxiv
Commentary: Remdesivir and interferon fall flat in WHO’s megastudy of COVID-19 treatments – Science
Commentaries on Twitter
Results of the @WHO SOLIDARITY trial:
4 drugs tested in 11,266 patients with COVID in 405 hospitals in 30 countries:
– hydroxychloroquine
– lopinavir
– remdesevir
– interferonNo clear benefit of any of them on survival. https://t.co/ohtTAFaSnc pic.twitter.com/2fO9E8zs8h
— Martin Landray (@MartinLandray) October 16, 2020
This is blockbuster from @WHO: 'Remdesivir, Hydroxychloroquine, Lopinavir and Interferon regimens have little or no effect on hospitalized COVID-19, as indicated by mortality, initiation of ventilation and duration of hospital stay. @medrxivpreprint https://t.co/aNGLzLL5uW pic.twitter.com/daOAMVW62u
— Harlan Krumholz (@hmkyale) October 15, 2020
Scientific consensus on the COVID-19 pandemic: we need to act now
16 Oct, 2020 | 09:41h | UTCScientific consensus on the COVID-19 pandemic: we need to act now – The Lancet