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KDIGO Controversies Conference on onco-nephrology
30 Oct, 2020 | 01:03h | UTC
Commentary on Twitter
.@goKDIGO Controversies Conference on onco-nephrology: understanding kidney impairment and solid-organ malignancies, and managing kidney cancer ca. 2020 from @Kidney_Int #Nephpearls#Onconephrology 🦀
👉🏼 https://t.co/u6ANtXdKfy pic.twitter.com/4xJ0gGohoE— Edgar V. Lerma 🇵🇭 (@edgarvlermamd) October 28, 2020
Randomized phase 2 trial: SARS-CoV-2 neutralizing antibody LY-CoV555 in outpatients with Covid-19
29 Oct, 2020 | 09:16h | UTCAudio Interview: A New Monoclonal Antibody for Covid-19 – New England Journal of Medicine
Commentaries on Twitter
BLAZE-1🔥 – outpatient trial of LY-Cov555, mAb recently dropped from ACTIV-3 inpatient trial
Only 1 of the 3 mAb dosages (middle one 🤷♂️) ⬇️ VL by d11
mAb assoc with modest ⬇️ in healthcare visits (1.6% vs 6.3% for placebo)
😑 Far from a game changerhttps://t.co/zZMGlodaaF pic.twitter.com/ofs1UgN1ZA
— Ilan Schwartz is on🦋 (@GermHunterMD) October 28, 2020
Phase 2 Lilly #SARSCoV2 monoclonal antibody outpatient trial just published @NEJM
The lack of a dose response for viral load reduction +modest effects on symptoms do not make this look like a potent intervention https://t.co/oyRG8fUNHf pic.twitter.com/uobuCIznmD— Eric Topol (@EricTopol) October 28, 2020
Humoral immune response to SARS-CoV-2 in Iceland
29 Oct, 2020 | 09:18h | UTCHumoral Immune Response to SARS-CoV-2 in Iceland – New England Journal of Medicine
Editorial: The Power of Antibody-Based Surveillance – New England Journal of Medicine
Video: Coronavirus update with Anthony Fauci – October 28, 2020
29 Oct, 2020 | 09:11h | UTCCoronavirus Update With Anthony Fauci – October 28, 2020 – JAMA
Clinical practice: Mild or moderate Covid-19
29 Oct, 2020 | 09:12h | UTCMild or Moderate Covid-19 – New England Journal of Medicine
What defines an efficacious COVID-19 vaccine? A review of the challenges assessing the clinical efficacy of vaccines against SARS-CoV-2
29 Oct, 2020 | 09:09h | UTC
Commentary on Twitter
NEW—What defines an efficacious #COVID19 vaccine? Experts @JennerInstitute@OxfordVacGroup @OxPrimaryCare & @OxfordBRC outline key challenges for assessing clinical efficacy of vaccines against SARS-CoV-2 @TheLancetInfDis https://t.co/QsLnLdUiYE pic.twitter.com/skpb0rfSdF
— The Lancet (@TheLancet) October 28, 2020
Clinical Decisions: Elective surgery during the Covid-19 pandemic
29 Oct, 2020 | 09:14h | UTCElective Surgery during the Covid-19 Pandemic – New England Journal of Medicine
Randomized trial: Validation of an enhanced recovery after surgery protocol in gynecologic surgery
29 Oct, 2020 | 09:07h | UTCRelated Systematic Review: Multicomponent hospital-led interventions to reduce hospital stay for older adults following elective surgery: a systematic review – Health Services and Delivery Research AND Summary: People leave hospital after surgery sooner if hospitals follow ‘enhanced recovery protocols’ – NIHR
See also: Complete List of Enhanced Recovery After Surgery (ERAS) Society Guidelines (free articles)
Commentary on Twitter
Validation of an enhanced recovery after surgery protocol in gynecologic surgery: an Italian randomized study- https://t.co/VRZ1LKzEvJ pic.twitter.com/2G1InEcIEZ
— AJOG (@AJOG_thegray) October 27, 2020
Report: Robust neutralizing antibodies to SARS-CoV-2 infection persist for months
29 Oct, 2020 | 09:08h | UTCRobust neutralizing antibodies to SARS-CoV-2 infection persist for months – Science
Commentary on Twitter
Just published @ScienceMagazine. >30,000 people w/mild to moderate #COVID19 have excellent IgG antibody titers for several months. No disappearing act. Important👍👍https://t.co/4kCZY8qcmo @MountSinaiNYC @FatimaAmanat @DrDavidReich @florian_krammer @IcahnMountSinai et al
, pic.twitter.com/B3LJ6JaBDa— Eric Topol (@EricTopol) October 28, 2020
Randomized trial: Osimertinib in resected EGFR-Mutated non–small-cell lung cancer
29 Oct, 2020 | 09:04h | UTCOsimertinib in Resected EGFR-Mutated Non–Small-Cell Lung Cancer – New England Journal of Medicine
A systematic review of rehabilitation and exercise recommendations in oncology guidelines
29 Oct, 2020 | 09:02h | UTC
Commentary on Twitter
Improving the integration of rehabilitation into cancer care: A review of #oncology guidelines and their recommendations for #rehabilitation and #exercise https://t.co/QRerXhhGON #cancerehab #exerciseoncology @NicoleStoutPT @JulieSilverMD @KarenPhysio @DR_SantaMina @WVUCancer pic.twitter.com/kObsSMRN9A
— CA: A Cancer Journal for Clinicians (@CACancerJournal) October 27, 2020
Systematic review: PCSK9 monoclonal antibodies for the primary and secondary prevention of cardiovascular disease
29 Oct, 2020 | 08:57h | UTCSummary: PCSK9 inhibitors for prevention of cardiovascular disease – Cochrane Library
The ‘Ten Commandments’ in the new ESC Adult Congenital Heart Disease Guidelines
29 Oct, 2020 | 08:59h | UTCOriginal guideline and commentaries: 2020 ESC Guidelines for the management of adult congenital heart disease
Podcast – Sinusitis: It’s Not That Tricky
29 Oct, 2020 | 08:55h | UTC#239 Sinusitis: It’s Not That Tricky – The Curbsiders Internal Medicine Podcast
Ten tips to optimize weaning and extubation success in the critically ill
29 Oct, 2020 | 08:50h | UTCTen tips to optimize weaning and extubation success in the critically ill – Intensive Care Medicine
Commentary on Twitter
Wean/extubate critically ills
1⃣optimize (⬇️) sedation
2⃣diaphragm-protective MV
3⃣daily screen for SBT
4⃣best SBT?
5⃣weaning strategy
6⃣what if SBT fails
7⃣muscle load/efficiency ratio
8⃣weaning/extubation failure
9⃣post-extubation support
🔟 tracheostomyhttps://t.co/TaYdzMvisK pic.twitter.com/q9qQOVKioZ— Intensive Care Medicine (@yourICM) October 27, 2020
WHO warns giving up on efforts to control Covid-19 would be ‘dangerous’
28 Oct, 2020 | 09:09h | UTCWHO warns giving up on efforts to control Covid-19 would be ‘dangerous’ – STAT
[Preprint] Cognitive deficits in people who have recovered from COVID-19 relative to controls: An N=84,285 online study
28 Oct, 2020 | 09:14h | UTCCommentaries: Recovered COVID-19 patients exhibit cognitive deficits – News Medical AND Expert reaction to preprint suggesting patients who recovered from COVID-19 could suffer serious cognitive decline – Science Media Centre
CDC Report on health care personnel hospitalized with COVID-19
28 Oct, 2020 | 09:17h | UTCCommentary: Nurses Make Up Most Hospitalized Coronavirus Health Care Workers, CDC Finds – U.S. News
Commentary on Twitter (thread – click for more)
BREAKING—huge CDC report on hospitalized healthcare workers w/ #COVID19, which comprise 1 in 16.7 (6%) of all hospitalized cases!
📌10% hospitalized had zero risk factor! (Median age only 49, so not old at all)
📌Whopping 36% hospitalized were nurses! 🧵https://t.co/IFRQSgWD8T pic.twitter.com/RtMeaX0lIN
— Eric Feigl-Ding (@DrEricDing) October 26, 2020
Lilly antibody drug fails in a Covid-19 study; others go on
28 Oct, 2020 | 09:10h | UTCLilly antibody drug fails in a Covid-19 study; others go on – CNBC
Outpatient management of COVID-19: Rapid evidence review
28 Oct, 2020 | 09:11h | UTCOutpatient Management of COVID-19: Rapid Evidence Review – American Family Physician
Covid-19 and the athletic heart: Emerging perspectives on pathology, risks, and return to play
28 Oct, 2020 | 09:06h | UTCAuthor Interview: COVID-19 and the Athletic Heart: Emerging Perspectives on Pathology, Risks, and Return-to-Play
Commentary on Twitter
The heart in athletes with #Covid19.
Summary of knowledge base, which is limited, and recommendations for rest and return to play https://t.co/4JBVO7nvAE @JAMACardio— Eric Topol (@EricTopol) October 26, 2020
Perspective: Understanding COVID-19 vaccine efficacy
28 Oct, 2020 | 09:04h | UTCUnderstanding COVID-19 vaccine efficacy – Science
Commentary on Twitter
Having reliable evidence on direct & indirect protection #COVID19 candidate vaccines provide can help plan how to use approved vaccines in a coordinated way, write @mlipsitch & @nataliexdean in this #SciMagPerspective. https://t.co/AjAvrsGLb8 pic.twitter.com/CuKQ94NPE8
— Science Magazine (@ScienceMagazine) October 26, 2020
Study: Effectiveness of face masks in preventing airborne transmission of SARS-CoV-2
28 Oct, 2020 | 09:08h | UTCEffectiveness of Face Masks in Preventing Airborne Transmission of SARS-CoV-2 – mSphere
Commentary on Twitter
Study using actual #SARSCoV2, showing masks both prevent transmission and also protect uninfected people from inhaling the virus.
Both cotton and surgical masks blocked 50% of transmission, and even a cotton mask was able to reduce uptake by 20-40%.https://t.co/w3eLiVZ4CS pic.twitter.com/MlrgBL15Zl
— Dr Zoë Hyde (@DrZoeHyde) October 27, 2020
USPSTF draft statement now recommends starting colorectal cancer screening at 45
28 Oct, 2020 | 08:57h | UTCDraft Recommendation Statement: Colorectal Cancer Screening – U.S. Preventive Services Task Force
Commentaries: Colorectal cancer screening should start five years earlier — at 45 — expert panel says – STAT AND USPSTF Lowers Colorectal Cancer Screening Age to 45 in Draft Recommendation – NEJM Journal Watch
Latin America’s embrace of an unproven COVID treatment is hindering drug trials
28 Oct, 2020 | 09:01h | UTCLatin America’s embrace of an unproven COVID treatment is hindering drug trials – Nature