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fMRI identifies smell and taste malfunction in COVID-19 patients

2 Feb, 2021 | 01:16h | UTC

fMRI Identifies Smell and Taste Malfunction in COVID-19 Patients – Clinical Imaging

Original study: Absent Blood Oxygen Level–Dependent Functional Magnetic Resonance Imaging Activation of the Orbitofrontal Cortex in a Patient With Persistent Cacosmia and Cacogeusia After COVID-19 Infection – JAMA Neurology

 

Commentary on Twitter

 

Post severe COVID-19, CT reveals potentially lifetime lung damage in one-thirds of patients

2 Feb, 2021 | 01:19h | UTC

Post-COVID-19, CT Reveals Potentially Lifetime Lung Damage in One-Thirds of Patients – Diagnostic Imaging

Original Study: Six-Month Follow-up Chest CT findings after Severe COVID-19 Pneumonia – Radiology

 

COVID-19 rarely spreads through surfaces. So why are we still deep cleaning?

2 Feb, 2021 | 01:20h | UTC

COVID-19 rarely spreads through surfaces. So why are we still deep cleaning? – Nature

 

COVID-19 vaccine-linked adenopathies could mimic breast malignancies

2 Feb, 2021 | 01:17h | UTC

COVID-19 Vaccine-Linked Adenopathies Could Mimic Breast Malignancies – Diagnostic Imaging

Original Study: Unilateral axillary Adenopathy in the setting of COVID-19 vaccine – Clinical Imaging

 

Commentaries on Twitter

 

Study estimates vaccines against 10 pathogens prevented 37 million deaths in low- and middle-income countries in the last 20 years

1 Feb, 2021 | 01:44h | UTC

Estimating the health impact of vaccination against ten pathogens in 98 low-income and middle-income countries from 2000 to 2030: a modelling study – The Lancet

Commentaries: Vaccines work: a reason for celebration and renewed commitment – The Lancet AND Study estimates that, without vaccination against 10 diseases, mortality in children under five would be 45% higher in low-income and middle-income countries – The Lancet AND Vaccines against 10 diseases prevented 37 million deaths in low- and middle-income countries in the last 20 years – London School of Hygiene & Tropical Medicine

 

Commentary on Twitter

 

Seven technologies to watch in 2021

1 Feb, 2021 | 01:42h | UTC

Seven technologies to watch in 2021 – Nature

 

WHO publishes new Essential Diagnostics List and urges countries to prioritize investments in testing

1 Feb, 2021 | 01:46h | UTC

WHO publishes new Essential Diagnostics List and urges countries to prioritize investments in testing – World Health Organization

WHO Report: The selection and use of essential in vitro diagnostics – TRS 1031

 

Randomized trial: Conservative fluid management strategy vs. usual care in participants after cardiac surgery

1 Feb, 2021 | 01:39h | UTC

A Multicenter, Open-Label, Randomized Controlled Trial of a Conservative Fluid Management Strategy Compared With Usual Care in Participants After Cardiac Surgery: The Fluids After Bypass Study – Critical Care Medicine

 

Association of dilated perivascular spaces with cognitive decline and incident dementia

1 Feb, 2021 | 01:38h | UTC

The Association of Dilated Perivascular Spaces with Cognitive Decline and Incident Dementia – Neurology (link to abstract – $ for full-text)

Commentaries: Large, Fluid-Filled Spaces Seen on Brain MRI Could Indicate Future Dementia – Diagnostic Imaging AND Perivascular Space Pathology Linked to Dementia in Seniors – HealthDay

 

Commentary on Twitter

 

Decentralized clinical trials: Collaboration is needed to drive their adoption and impact

1 Feb, 2021 | 01:40h | UTC

Decentralized clinical trials: Collaboration is needed to drive their adoption and impact – STAT

 

Blood test to detect psychogenic nonepileptic seizures shows promise

1 Feb, 2021 | 01:37h | UTC

Blood Test to Detect Psychogenic Nonepileptic Seizures Shows Promise – Physician’s Weekly

Original study: Association of Epileptic and Non-epileptic Seizures and Changes in Circulating Plasma Proteins Linked to Neuroinflammation – Neurology (link to abstract – $ for full-text)

 

An analysis of contemporary oncology randomized clinical trials from low/middle-income vs. high-income countries

1 Feb, 2021 | 01:36h | UTC

An Analysis of Contemporary Oncology Randomized Clinical Trials From Low/Middle-Income vs High-Income Countries – JAMA Oncology (free for a limited period)

Editorial: Aligning Cancer Clinical Trials With Cancer Burden: Need for Greater Global Leadership, Resources, and Vision – JAMA Oncology

 

ASCO Guideline: Neoadjuvant chemotherapy, endocrine therapy, and targeted therapy for breast cancer

1 Feb, 2021 | 01:34h | UTC

Neoadjuvant Chemotherapy, Endocrine Therapy, and Targeted Therapy for Breast Cancer: ASCO Guideline – Journal of Clinical Oncology

 

Consensus statement recommends individualizing surveillance mammography for older patients after treatment for early-stage breast cancer

1 Feb, 2021 | 01:33h | UTC

Individualizing Surveillance Mammography for Older Patients After Treatment for Early-Stage Breast Cancer: Multidisciplinary Expert Panel and International Society of Geriatric Oncology Consensus Statement – JAMA Oncology

Commentaries: First Mammography Guidelines Released for Older Breast Cancer Survivors – Diagnostic Imaging AND New Surveillance Mammography Screening Guidelines Issued for Breast Cancer Survivors Aged 75 and Older – The ASCO Post

 

[Not published yet] Full-dose Heparin best for moderate COVID-19 regardless of D-dimer — Data released from ACTIV-4a, ATTACC, and REMAP-CAP trials

1 Feb, 2021 | 01:58h | UTC

Full-Dose Heparin Best for Moderate COVID-19 Regardless of D-dimer — Data released from ACTIV-4a, ATTACC, and REMAP-CAP trials – MedPage Today (free registration required)

Trial results: ATTACC, ACTIV-4a & REMAP-CAP multiplatform RCT Results of interim analysis – ATTACC Trial

News release: Full-dose blood thinners decreased need for life support and improved outcome in hospitalized COVID-19 patients – National Institutes of Health

 

New Updates to the Surviving Sepsis Campaign COVID-19 Guidelines

1 Feb, 2021 | 01:56h | UTC

Surviving Sepsis Campaign Guidelines on the Management of Adults With Coronavirus Disease 2019 (COVID-19) in the ICU – Critical Care Medicine

Additional resources: COVID-19 Guidelines – Surviving Sepsis Campaign

 

Commentary on Twitter

 

Analysis: J&J and Novavax Data

1 Feb, 2021 | 01:54h | UTC

J&J and Novavax Data – In the Pipeline

 

[Press release – not published yet] Single-shot Janssen COVID-19 vaccine candidate met primary endpoints in interim analysis of its phase 3 trial

1 Feb, 2021 | 01:55h | UTC

News release: Johnson & Johnson Announces Single-Shot Janssen COVID-19 Vaccine Candidate Met Primary Endpoints in Interim Analysis of its Phase 3 ENSEMBLE Trial

Commentaries: J&J’s one-shot COVID vaccine offers hope for faster protection – Nature AND Johnson & Johnson Executive Says Vaccine Works Where It Counts: Preventing Deaths – NPR AND Novavax’s COVID Vaccine Shows High Efficacy In Trials; J&J One-Dose Shot Less So – As Europe Feuds With AstraZeneca – Health Policy Watch AND Covid vaccine: Single-dose Johnson & Johnson jab is 66% effective – BBC AND Johnson & Johnson’s COVID-19 Vaccine Results Are Better Than They May Sound – TIME AND Expert reaction to Johnson & Johnson announcing that the single-shot Janssen COVID-19 vaccine candidate met primary endpoints in the interim analysis of its phase 3 ENSEMBLE Trial – Science Media Centre AND Janssen Investigational COVID-19 Vaccine: Interim Analysis of Phase 3 Clinical Data Released – NIH News Releases AND J&J one-dose Covid vaccine is 66% effective, a weapon but not a knockout punch – STAT

 

SARS-CoV-2 vaccines and the growing threat of viral variants

1 Feb, 2021 | 01:50h | UTC

SARS-CoV-2 Vaccines and the Growing Threat of Viral Variants – JAMA

 

How to redesign COVID vaccines so they protect against variants: lineages that can evade immunity are spurring vaccine makers to explore ways to redesign their shots

1 Feb, 2021 | 01:52h | UTC

How to redesign COVID vaccines so they protect against variants – Nature

See also: Vaccine 2.0: Moderna and other companies plan tweaks that would protect against new coronavirus mutations – Science (a few articles per month are free)

 

The most worrying mutations in five emerging coronavirus variants

1 Feb, 2021 | 01:50h | UTC

The Most Worrying Mutations in Five Emerging Coronavirus Variants – Scientific American

 

Analysis: Covid-19 pandemic and the social determinants of health

1 Feb, 2021 | 01:49h | UTC

Covid-19 pandemic and the social determinants of health – The BMJ

 

Public health actions to control new SARS-CoV-2 variants

1 Feb, 2021 | 01:47h | UTC

Public health actions to control new SARS-CoV-2 variants – Cell

 

Commentary on Twitter (thread – click for more)

 

Explaining covid-19 performance: 10 factors might predict national responses

1 Feb, 2021 | 01:48h | UTC

Explaining covid-19 performance: what factors might predict national responses? – The BMJ

 

Commentary on Twitter

https://twitter.com/martinmckee/status/1355040216097165317

 

WHO issues new 10-year plan to end suffering from neglected tropical diseases

29 Jan, 2021 | 01:39h | UTC

News release: WHO issues new 10-year plan to end suffering from neglected tropical diseases – World Health Organization

Report, executive summary and more: Ending the neglect to attain the Sustainable Development Goals: A road map for neglected tropical diseases 2021–2030 – World Health Organization

Commentary: New WHO Roadmap Sets Ambitious Targets To Reduce By 90% Neglected Tropical Disease Burden Within Decade – Health Policy Watch

 

Commentary on Twitter (thread – click for more)

 

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