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Cohort study: Increased consumption of refined grains linked to higher risk of mortality and major cardiovascular disease events
5 Feb, 2021 | 01:30h | UTCCommentaries: Refined carbs like white bread, pasta, and pastries could increase risk of early death, a study found – Insider AND High intake of refined grains linked to higher risk of heart disease and death – The BMJ
RCT: MRI-targeted biopsy safely reduces the need for biopsy in more than one-third of men at risk for prostate cancer
5 Feb, 2021 | 01:27h | UTCCommentary: Clinical trial: Using MRI for prostate cancer diagnosis equals or beats current standard – Ontario Institute for Cancer Research AND Another Win for MRI and Targeted Prostate Biopsy – MedPage Today (free registration required)
Related: MRI-Targeted, Systematic, and Combined Biopsy for Prostate Cancer Diagnosis – New England Journal of Medicine (study and commentaries) Negative Predictive Value of Multiparametric Magnetic Resonance Imaging in the Detection of Clinically Significant Prostate Cancer in the Prostate Imaging Reporting and Data System Era: A Systematic Review and Meta-analysis – European Urology AND Meta-Analysis: MRI plus Targeted Biopsy vs. Systematic Biopsy Alone for the Diagnosis of Prostate Cancer (studies and commentaries)
RCT: No difference in kidney allograft survival in kidney transplant patients allocated to early corticosteroid cessation vs. long-term corticosteroid therapy
5 Feb, 2021 | 01:26h | UTCEarly Corticosteroid Cessation vs Long-term Corticosteroid Therapy in Kidney Transplant Recipients: Long-term Outcomes of a Randomized Clinical Trial – JAMA Surgery (free for a limited period)
Commentary: Long-Term Corticosteroids Not Necessary After Kidney Transplant – Physician’s Weekly AND Is it OK to Cut Back on Prednisone After Kidney Transplant? – MedPage Today (free registration required)
Commentary on Twitter
16 years of follow up there was no difference in allograft or patient survival between kidney transplant patients treated with tacrolimus and MMF maintenance immunosuppression who were randomized to continue or withdraw #corticosteroids https://t.co/dQijSfgZJE #nosteroids pic.twitter.com/DbG6RFKFdp
— JAMA Surgery (@JAMASurgery) February 3, 2021
Opinion: Peer reviewers—time for mass rebellion?
5 Feb, 2021 | 01:24h | UTCRichard Smith: Peer reviewers—time for mass rebellion? – The BMJ Opinion
Health in dust belt cities and beyond
5 Feb, 2021 | 01:29h | UTCHealth in dust belt cities and beyond—an essay by Nick Middleton – The BMJ
Commentary on Twitter
Desert dust is associated with morbidity and mortality and has global ramifications. What are its health impacts and how can we mitigate the harms?https://t.co/e2oCKxU2GY#virtualWISH2020 @WISHQatar
— The BMJ (@bmj_latest) February 4, 2021
5 things we learned about peer review in 2020
5 Feb, 2021 | 01:25h | UTC5 Things We Learned About Peer Review in 2020 – Absolutely Maybe
Review: Dysphagia in older adults
5 Feb, 2021 | 01:22h | UTCDysphagia in Older Adults – Mayo Clinic Proceedings
Telemedicine and team-based care: The perils and the promise
5 Feb, 2021 | 01:23h | UTCTelemedicine and Team-Based Care – Mayo Clinic Proceedings
The Evolving Immunotherapy Landscape and the Epidemiology, Diagnosis, and Management of Cardiotoxicity: JACC: CardioOncology Primer
5 Feb, 2021 | 01:19h | UTC
SR/MA: Colistin nephrotoxicity
5 Feb, 2021 | 01:21h | UTC
Opinion: Vaccine Nationalism Harms Everyone and Protects No One
5 Feb, 2021 | 01:45h | UTCVaccine Nationalism Harms Everyone and Protects No One – Foreign Policy
Related: Jeremy Farrar: Until we are all safe, no one is safe. Covid is a global problem – The Guardian AND Covid-19: WHO warns against “vaccine nationalism” or face further virus mutations – The BMJ AND ‘Vaccine nationalism’ threatens global plan to distribute COVID-19 shots fairly – Science AND WHO chief warns against ‘catastrophic moral failure’ in COVID-19 vaccine access – United Nations
NIH Treatment Guideline Update: “there are insufficient data to recommend either for or against the use of tocilizumab or sarilumab for the treatment of COVID-19”
5 Feb, 2021 | 01:44h | UTC
Study: Adults between 20 and 49 years responsible for most Covid-19 spread
5 Feb, 2021 | 01:43h | UTCAge groups that sustain resurging COVID-19 epidemics in the United States – Science
Commentaries: Adults 20 to 49 may have driven 72% of US COVID-19 surges – CIDRAP AND Younger adults responsible for most of COVID-19 spread: Study – ABC News
Study: Single dose Pfizer Covid-19 vaccine effectiveness estimated at 90% after 21 days
5 Feb, 2021 | 01:43h | UTCCommentaries: One Pfizer/BioNTech jab gives ‘90% immunity’ from Covid after 21 days – The Guardian AND Expert reaction to preprint reanalysing study of real-world Pfizer vaccination outcomes after one dose from Israel – Science Media Centre
Commentary on Twitter
A study on "real world" effects of vaccination in Israel
🥳 Single dose 90% effective at 21d 🥳
"…results coming from Israel support the UK policy of extending the gap between doses by showing that a single dose can give a high level of protection."https://t.co/smnZUPJkZp
— Alasdair Munro (@apsmunro) February 4, 2021
Phase 1/2 Clinical Trial: CoronaVac is safe and well tolerated in older adults. Neutralizing antibodies were detected in over 90% of participants in all groups
5 Feb, 2021 | 01:41h | UTCCommentary: Inactivated COVID-19 vaccines to make a global impact – The Lancet Infectious Diseases
Commentary on Twitter
https://twitter.com/hildabast/status/1357281190198140929
New COVID-19 vaccines: here’s how the promising Novavax and Johnson & Johnson jabs work
5 Feb, 2021 | 01:41h | UTC
Impact of COVID-19 on cancer care has been ‘profound’, warns UN health agency
5 Feb, 2021 | 01:38h | UTCImpact of COVID-19 on cancer care has been ‘profound’, warns UN health agency – UN News
Dialysis patients have 4-fold greater risk of dying from COVID-19
5 Feb, 2021 | 01:39h | UTCNews Release: Dialysis patients have 4-fold greater risk of dying from COVID-19 – Canadian Medical Association Journal
Original Study: COVID-19 in patients undergoing long-term dialysis in Ontario – Canadian Medical Association Journal
Why the WHO won’t call it the ‘U.K. variant’, and you shouldn’t either
5 Feb, 2021 | 01:40h | UTCWhy the WHO won’t call it the ‘U.K. variant’, and you shouldn’t either – CTV News
Related: The world needs a single naming system for coronavirus variants – Nature
Policy Statement: Antibiotic Stewardship in Pediatrics
4 Feb, 2021 | 01:21h | UTCAntibiotic Stewardship in Pediatrics – Pediatrics
Commentary: Guidance Provided for Antibiotic Stewardship in Pediatrics
COVID’s mental-health toll: how scientists are tracking a surge in depression
5 Feb, 2021 | 01:36h | UTCCOVID’s mental-health toll: how scientists are tracking a surge in depression – Nature
Related: Trends in US Emergency Department Visits for Mental Health, Overdose, and Violence Outcomes Before and During the COVID-19 Pandemic – JAMA Psychiatry AND Mental Health, COVID-19, and the Invisible Pandemic on the Horizon – Mayo Clinic Proceedings
Randomized trial: Safety and efficacy of long-term mild hypothermia for severe traumatic brain injury with refractory intracranial hypertension
4 Feb, 2021 | 01:18h | UTC
Commentary on Twitter
Does induced hypothermia/targetted temp management improve outcomes in patients with traumatic brain injury?
Maybe or maybe not
But this trial slow to cool, not very cool, underpowered and mod rate of dropout
Prob does not answer questionhttps://t.co/UGRFmUVNV0 pic.twitter.com/c0iDqj2l2e
— Graham Nichol (@grahamnichol) January 29, 2021
Prevalence and trends in tobacco use among adolescents aged 13–15 years in 143 countries, 1999–2018: findings from the Global Youth Tobacco Surveys
4 Feb, 2021 | 01:20h | UTCPrevalence and trends in tobacco use among adolescents aged 13–15 years in 143 countries, 1999–2018: findings from the Global Youth Tobacco Surveys – The Lancet Child & Adolescent Health (link to abstract – $ for full-text)
Commentary on Twitter
NEW—Global Youth Tobacco Surveys data from 13–15-year-olds in 140 countries, suggests 40% of countries show no progress in reducing cigarette smoking in adolescents over the past 20 years. Read more findings from the @LancetChildAdol study: https://t.co/qlHzvHHdOD
— The Lancet (@TheLancet) February 3, 2021
State of the Art Review: Uveitis for the non-ophthalmologist
4 Feb, 2021 | 01:22h | UTCUveitis for the non-ophthalmologist – The BMJ (free for a limited period)
Consensus statement for perioperative care in lumbar spinal fusion: Enhanced Recovery After Surgery (ERAS®) Society recommendations
4 Feb, 2021 | 01:15h | UTC