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Covid-19: Four in 10 people with evidence of past infection had no classic symptoms, study finds

10 Feb, 2021 | 01:48h | UTC

Covid-19: Four in 10 people with evidence of past infection had no classic symptoms, study finds – The BMJ

 


CDC report: Mask mandates associated with decline in COVID-19 hospitalizations

10 Feb, 2021 | 01:43h | UTC

Decline in COVID-19 Hospitalization Growth Rates Associated with Statewide Mask Mandates — 10 States, March–October 2020 – CDC Morbidity and Mortality Weekly Report

Commentary: Mask mandates can work, CDC researchers say – CNN

 


What if we never reach herd immunity?

10 Feb, 2021 | 01:46h | UTC

What If We Never Reach Herd Immunity? – The Atlantic

Related: We May Never Get to Herd Immunity – Think Global Health

 


Defining the role of asymptomatic and pre-symptomatic SARS-CoV-2 transmission – a living systematic review

10 Feb, 2021 | 01:45h | UTC

Defining the role of asymptomatic and pre-symptomatic SARS-CoV-2 transmission – a living systematic review – Clinical Microbiology and Infection

Related: Infectivity of asymptomatic versus symptomatic COVID-19 – The Lancet AND Asymptomatic transmission of covid-19 – The BMJ

 


Face masks help control transmission of COVID-19, study finds

10 Feb, 2021 | 01:41h | UTC

Mask-wearing and control of SARS-CoV-2 transmission in the USA: a cross-sectional study – The Lancet Digital Health

Commentaries: Face masks help control transmission of COVID-19 – The Lancet Digital Health AND Mask-wearing together with social distancing has maximum impact on COVID-19, study finds – News Medical

 


Breast Cancer Risk Genes — Association Analysis in More than 113,000 Women

10 Feb, 2021 | 01:07h | UTC

Breast Cancer Risk Genes — Association Analysis in More than 113,000 Women – New England Journal of Medicine

Commentary: Protein-Truncating and Rare Missense Variants in Breast Cancer Risk Genes: Association With Disease Risk – The ASCO Post

 


Cohort study: Low risk of progression to diabetes among older adults with “prediabetes”

9 Feb, 2021 | 01:09h | UTC

Risk of Progression to Diabetes Among Older Adults With Prediabetes – JAMA Internal Medicine (free for a limited period)

Commentaries: “Prediabetes” Diagnosis Less Useful in Older Patients – Johns Hopkins Bloomberg School of Public Health AND Prediabetes—A Risk Factor Twice Removed – JAMA Internal Medicine (free for a limited period) AND How many pre-diabetics go on to develop diabetes? – MedicalResearch.com

Author Interview: Risk of Progression to Diabetes Among Older Adults With Prediabetes

Related: The war on ‘prediabetes’ could be a boon for pharma—but is it good medicine? – Science

 


A population-based study of genes previously implicated in breast cancer

10 Feb, 2021 | 01:05h | UTC

A Population-Based Study of Genes Previously Implicated in Breast Cancer – New England Journal of Medicine (link to abstract – $ for full-text)

 


EBM: “The sensitivity and specificity are lying to you”

9 Feb, 2021 | 01:01h | UTC

The sensitivity and specificity are lying to you – First10Em

 


Choosing Wisely for Critical Care: The Next Five

9 Feb, 2021 | 01:07h | UTC

Choosing Wisely For Critical Care: The Next Five – Critical Care Medicine

Related: Critical Care Societies Collaborative – Critical Care: Five Things Physicians and Patients Should Question – Choosing Wisely

See complete lists of low-value practices: Choosing Wisely U.S. / Choosing Wisely UK / Choosing Wisely Australia AND Choosing Wisely Canada

 

Commentary on Twitter

 


Review: Nosocomial infection in the ICU setting

9 Feb, 2021 | 01:05h | UTC

Nosocomial Infection – Critical Care Medicine

 


Canadians Win Again – Syncope Score Systematic Review

9 Feb, 2021 | 01:03h | UTC

Canadians Win Again – Syncope Score Systematic Review – Journal Feed

Original study: Multivariable risk scores for predicting short‐term outcomes for emergency department patients with unexplained syncope: A systematic review – Academic Emergency Medicine

See calculator: Canadian Syncope Risk Score – MdCalc

 


RCT: Dobutamine-sparing vs. dobutamine-to-all strategy in cardiac surgery

9 Feb, 2021 | 00:57h | UTC

Dobutamine-sparing versus dobutamine-to-all strategy in cardiac surgery: a randomized noninferiority trial – Annals of Intensive Care

 


RCT: Total Body Irradiation vs. Chemotherapy Conditioning in Childhood ALL

9 Feb, 2021 | 00:39h | UTC

Total Body Irradiation or Chemotherapy Conditioning in Childhood ALL: A Multinational, Randomized, Noninferiority Phase III Study – Journal of Clinical Oncology

Commentary: TBI Beats Chemoconditioning for ALL Transplants in Children – Medscape (free registration required)

 

Commentary on Twitter

 


FDA Drug Safety Communication: Initial safety trial results find Tofacitinib, used for arthritis and ulcerative colitis, may increase the risk of serious heart-related problems and cancer

9 Feb, 2021 | 01:00h | UTC

Xeljanz, Xeljanz XR (tofacitinib): Drug Safety Communication – Initial Safety Trial Results Find Increased Risk of Serious Heart-related Problems and Cancer with Arthritis and Ulcerative Colitis Medicine – U.S. Food & Drug Administration

Commentary: Arthritis, Colitis Drug Tied to Heart-Related Problems and Cancer – NEJM Journal Watch

 


Variant-proof vaccines — invest now for the next pandemic

9 Feb, 2021 | 01:39h | UTC

Variant-proof vaccines — invest now for the next pandemic – Nature

 


Thrombosis and COVID-19: Controversies and (Tentative) Conclusions

9 Feb, 2021 | 01:41h | UTC

Thrombosis and COVID-19: Controversies and (Tentative) Conclusions – Clinical Infectious Diseases

 

Commentary on Twitter

https://twitter.com/JohnRossMD/status/1357992429824081921

 


Small RCT: Peginterferon lambda increases viral clearance in outpatients with COVID-19

9 Feb, 2021 | 01:36h | UTC

Peginterferon lambda for the treatment of outpatients with COVID-19: a phase 2, placebo-controlled randomised trial – The Lancet Respiratory Medicine

 


Coronavirus vaccine strategy needs rethink after resistant variants emerge, say scientists

9 Feb, 2021 | 01:38h | UTC

Coronavirus vaccine strategy needs rethink after resistant variants emerge, say scientists – The Guardian

Related: South Africa halts AstraZeneca vaccine rollout over new variant – BBC AND ‘What other variants might be out there?’ An expert on viral evolution on what’s happening with coronavirus mutations – STAT AND Covid-19: Oxford vaccine offers less protection against South Africa variant (study and commentaries) AND South Africa suspends use of AstraZeneca’s COVID-19 vaccine after it fails to clearly stop virus variant – Science

 


Mitigating inequities and saving lives with ICU triage during the COVID-19 pandemic

9 Feb, 2021 | 01:29h | UTC

Mitigating Inequities and Saving Lives with ICU Triage during the COVID-19 Pandemic – American Journal of Respiratory and Critical Care Medicine

Commentary: More on the allocation of scarce medical resources during the pandemic, and a lack of consensus among bioethicists about how to proceed

 


Does taking Vitamin D prevent or treat COVID-19?

9 Feb, 2021 | 01:20h | UTC

Does Taking Vitamin D Prevent or Treat COVID-19? – HIV and ID Observations

 


ARDS: Contemporary management and novel approaches during COVID-19

9 Feb, 2021 | 01:31h | UTC

Acute Respiratory Distress Syndrome: Contemporary Management and Novel Approaches during COVID-19 – Anesthesiology

 

Commentary on Twitter

 


Perspective: Pregnancy, postpartum care, and COVID-19 vaccination in 2021

9 Feb, 2021 | 01:16h | UTC

Pregnancy, Postpartum Care, and COVID-19 Vaccination in 2021 – JAMA

 


Perspective: COVID-19 vaccination in pregnant and lactating women

9 Feb, 2021 | 01:18h | UTC

COVID-19 Vaccination in Pregnant and Lactating Women – JAMA

Related: Fauci says ‘no red flags’ seen in 10,000 pregnant women who’ve received Covid shots so far – CNBC

 


Patients with lymphoma receiving B-Cell–depleting therapies may be at greater risk for persistent COVID-19 infection

9 Feb, 2021 | 01:14h | UTC

Patients With Lymphoma Receiving B-Cell–Depleting Therapies May Be at Greater Risk for Persistent COVID-19 Infection – The ASCO Post

Related: Patients on Active Chemotherapy May Not Be at Increased Risk for COVID-19 Infection – The ASCO Post

See also: Anti-CD20 Drugs Tied to Severe COVID in Cancer Patients — Plus: Active chemo treatment may not be a COVID risk factor – MedPage Today (free registration required)

 


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