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Syphilis in Dermatology: Recognition and Management
This guide by Amor Khachemoune et al. discusses the current epidemiology of syphilis and focuses on practice aspects of diagnosis and management, including public health reporting.#Syphilis https://t.co/uLsVaw4jXP pic.twitter.com/sbXhFCk5De

— Kathy Fraser (@AmJClinDerma) January 23, 2023

SR | Fecal transplantation for treatment of inflammatory bowel disease

2 May, 2023 | 13:39h | UTC

Fecal transplantation for treatment of inflammatory bowel disease – Cochrane Library

Commentary: Expert reaction to two Cochrane reviews looking at stool transplants for recurrent Clostridium difficile infection, and for inflammatory bowel disease – Science Media Centre

Review | Helicobacter pylori infection

2 May, 2023 | 13:37h | UTC

Helicobacter pylori infection – Nature Reviews Disease Primers (if the link is paywalled, try this one)

Commentary on Twitter

A Primer published by @DiseasePrimers summarizes the epidemiology, pathophysiology, diagnosis and management of Helicobacter pylori infection, and discusses patient quality of life and open research questions. https://t.co/WawWpSGBU9 pic.twitter.com/ghFTbyp0ln

— Nature Portfolio (@NaturePortfolio) April 24, 2023

Cohort Study | Evaluation of brain-body health in individuals with common neuropsychiatric disorders

2 May, 2023 | 13:33h | UTC

Evaluation of Brain-Body Health in Individuals With Common Neuropsychiatric Disorders – JAMA Psychiatry (link to abstract – $ for full-text)

Interview: Evaluation of Brain-Body Health in Individuals With Common Neuropsychiatric Disorders – JAMA

Commentary from the author on Twitter (thread – click for more)

Mental illness is a brain disorder? Right?

We thought so.

Hang on though, our new study @JAMAPsych shows that poor body health is a more pronounced manifestation of mental illness than poor brain health.https://t.co/4TFlt7awEY

?1/9 pic.twitter.com/92ZJAQWQlb

— Ye Ella Tian (@yetianmed) April 27, 2023

RCT | Efficacy and safety of intraoperative hyperthermic intraperitoneal chemotherapy for locally advanced colon cancer

2 May, 2023 | 13:36h | UTC

Efficacy and Safety of Intraoperative Hyperthermic Intraperitoneal Chemotherapy for Locally Advanced Colon Cancer: A Phase 3 Randomized Clinical Trial – JAMA Surgery (free for a limited period)

Invited Commentary: Heated Intraperitoneal Chemotherapy for Locally Advanced Colon Cancer–Restarting the Fire – JAMA Surgery (free for a limited period)

Commentary on Twitter

Hyperthermic intraperitoneal chemotherapy with mitomycin C along with complete cytoreduction improved locoregional control in patients with locally advanced colorectal cancer and should be considered for treatment of locally advanced colorectal cancer. https://t.co/hOM4TvgILB

— JAMA Surgery (@JAMASurgery) April 26, 2023

Cohort Study | Infection-unrelated cancers are increasingly more common than infection-related cancers among individuals with HIV

2 May, 2023 | 13:32h | UTC

Age and Cancer Incidence in 5.2 Million People With Human Immunodeficiency Virus (HIV): The South African HIV Cancer Match Study – Clinical Infectious Diseases (free for a limited period)

Commentary: Infection-Unrelated Cancers Predominant Among Older Adults With HIV – Cancer Therapy Advisor

Commentary on Twitter

Age and Cancer Incidence in 5.2 Million People With Human Immunodeficiency Virus (HIV): The South African HIV Cancer Match Study

? Freely Availablehttps://t.co/LMlF30Zkry

— Clinical Infectious Diseases (@CIDJournal) April 30, 2023

RCT | Lung volume reduction surgery vs. endobronchial valves in patients with emphysema

2 May, 2023 | 13:29h | UTC

Lung volume reduction surgery versus endobronchial valves: a randomised controlled trial – European Respiratory Journal

Commentary on Twitter

ERJ: In this first randomised study to compare lung volume reduction surgery and endobronchial valve placement in people who are suitable for both treatments, surgery did not produce substantially superior outcomes at 1 year post-procedure https://t.co/cFIVZijSJg pic.twitter.com/ZqRCgxYwLS

— ERS publications (@ERSpublications) May 1, 2023

Clinical trial 2y update | Avelumab first-line maintenance for advanced urothelial carcinoma

2 May, 2023 | 13:30h | UTC

Avelumab First-Line Maintenance for Advanced Urothelial Carcinoma: Results From the JAVELIN Bladder 100 Trial After ≥2 Years of Follow-Up – Journal of Clinical Oncology

Original Article: Avelumab Maintenance Therapy for Advanced or Metastatic Urothelial Carcinoma – New England Journal of Medicine

RCT | Liso-cel, a CAR T-Cell therapy, significantly improves outcomes in large B-Cell lymphoma second-line treatment

2 May, 2023 | 13:28h | UTC

Lisocabtagene maraleucel as second-line therapy for large B-cell lymphoma: primary analysis of the phase 3 TRANSFORM study – Blood

Commentary: Lisocabtagene Maraleucel Bests Standard Care in LBCL – Cancer Therapy Advisor

M-A | Pain management interventions for the treatment of chronic low back pain

2 May, 2023 | 13:26h | UTC

Pain Management Interventions for the Treatment of Chronic Low Back Pain: A Systematic Review and Meta-Analysis – The Clinical Journal of Pain

CONSORT Harms 2022 statement, explanation, and elaboration: updated guideline for the reporting of harms in randomized trials

2 May, 2023 | 13:25h | UTC

CONSORT Harms 2022 statement, explanation, and elaboration: updated guideline for the reporting of harms in randomized trials – Journal of Clinical Epidemiology

RCT | Ventilation approaches in one-lung ventilation and pulmonary complications after major lung resection surgery

2 May, 2023 | 13:23h | UTC

One-lung ventilation and postoperative pulmonary complications after major lung resection surgery. A multicenter randomized controlled trial – Journal of Cardiothoracic and Vascular Anesthesia

Commentary on Twitter

One of the largest #RCTs on the management of one lung ventilation in #thoracicanesthesia (880 pts). https://t.co/ZVhTP5sv4o pic.twitter.com/KyLu4BE2yd

— Journal of Cardiothoracic and Vascular Anesthesia (@JCVAonline) April 30, 2023

Clinical aspects of snakebite envenoming and its treatment in low-resource settings

2 May, 2023 | 13:21h | UTC

Clinical aspects of snakebite envenoming and its treatment in low-resource settings – The Lancet (free registration required)

M-A | Low-dose triple and quadruple antihypertensives outperform monotherapy in blood pressure reduction

28 Apr, 2023 | 13:23h | UTC

Efficacy and Safety of Low-Dose Triple and Quadruple Combination Pills vs Monotherapy, Usual Care, or Placebo for the Initial Management of Hypertension: A Systematic Review and Meta-analysis – JAMA Cardiology (free for a limited period)

Commentary: Low-Dose Polypills Top Other Approaches for Initial BP Control: Meta-analysis – TCTMD

Oral anticoagulation in patients with advanced CKD and atrial fibrillation: beyond anticoagulation

2 May, 2023 | 13:20h | UTC

Oral Anticoagulation in Patients With Advanced Chronic Kidney Disease and Atrial Fibrillation: Beyond Anticoagulation – Mayo Clinic Proceedings

AHA Scientific Statement | Assessing popular diets in relation to 2021 American Heart Association dietary recommendations

28 Apr, 2023 | 13:21h | UTC

Top Things to Know: Popular Dietary Patterns: Alignment with AHA 2021 Dietary Guidance – American Heart Association

Commentary on Twitter

A ? scientific statement evaluates how well 10 popular eating patterns align with AHA nutrition guidance, offering a valuable tool for both clinicians and consumers to understand and adopt heart-healthy dietary patterns.
Read more ? https://t.co/PbGRqhF05p pic.twitter.com/sropKchRWx

— AHA Science (@AHAScience) April 27, 2023

Cohort Study | Risk of multiple morbidities across the lifespan in people with Down syndrome or intellectual disabilities

28 Apr, 2023 | 13:19h | UTC

Multiple morbidity across the lifespan in people with Down syndrome or intellectual disabilities: a population-based cohort study using electronic health records – The Lancet Public Health

Commentary from the author on Twitter (thread – click for more)

Our new report on Multiple morbidity across the lifespan in people with Down syndrome or intellectual disability is out today https://t.co/wkakUfjetn pic.twitter.com/fVyKZZPdOW

— Andre Strydom (@drandrestrydom) April 27, 2023

Global burden of chronic respiratory diseases and risk factors, 1990–2019

28 Apr, 2023 | 13:17h | UTC

Global burden of chronic respiratory diseases and risk factors, 1990–2019: an update from the Global Burden of Disease Study 2019 – eClinicalMedicine

News Release: Chronic respiratory disease is third leading cause of death globally with air pollution killing 1.3 million people – IHME

Commentary on Twitter (thread – click for more)

Modifiable risk factors like air pollution were responsible for roughly 70% of chronic respiratory disease (#CRD) deaths, finds new global burden of disease study published in @eClinicalMed @TheLancet ?

»https://t.co/uUVZFdNWVV pic.twitter.com/kgMXOePlfS

— Institute for Health Metrics and Evaluation (IHME) (@IHME_UW) April 25, 2023

RCT | Molecular point-of-care testing for gastroenteritis reduced isolation time but increased antibiotic use

28 Apr, 2023 | 13:15h | UTC

Clinical impact of syndromic molecular point-of-care testing for gastrointestinal pathogens in adults hospitalised with suspected gastroenteritis (GastroPOC): a pragmatic, open-label, randomised controlled trial – The Lancet Infectious Diseases

Commentary: Molecular testing in suspected infectious diarrhoea—the value of negative results – The Lancet Infectious Diseases

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