All Posts
British Society of Gastroenterology guidelines on the management of irritable bowel syndrome
29 Apr, 2021 | 08:31h | UTCBritish Society of Gastroenterology guidelines on the management of irritable bowel syndrome – Gut
Commentary on Twitter (thread – click for more)
Here are the new @BritSocGastro guidelines for #IBS in @Gut_BMJ! I'll summarize in 🧵 ⬇️⬇️⬇️!
😖💩🦠🧠🥦🍞💊#GITwitter #GI #gut #braingut #motility #DGBI #FGID #microbiome #probiotics #MedTwitter #MedEd https://t.co/zbXoPbKgHO
— John Damianos, M.D. (@john_damianosMD) April 26, 2021
AHA Scientific Statement: Close monitoring for heart risk needed if breast, prostate cancer treatment includes hormonal therapies
29 Apr, 2021 | 08:33h | UTCNews release: Close monitoring for heart risk needed if breast, prostate cancer treatment includes hormones – American Heart Association
Top Things to Know: Impact of Hormonal Therapies for Treatment of Hormone-Dependent Cancers (Breast and Prostate) on the Cardiovascular System – American Heart Association
Commentaries: Hormonal Therapy for Breast and Prostate Cancer: Lessons and Opportunities – American Heart Association AND Hormonal Based Therapies in the Treatment of Breast and Prostate Cancer – balancing the risks! – American Heart Association AND Hormone Cancer Therapies Increase CV Risk: AHA Scientific Statement – TCTMD AND Closely Monitor Heart Health in Cancer Patients Who Get Hormonal Therapies: AHA – HealthDay
M-A: Extended thromboprophylaxis after hospital discharge for medically ill patients with cancer – Extended thromboprophylaxis is not associated with a reduced rate of venous thromboembolic events and is associated with increased risk of hemorrhage
29 Apr, 2021 | 08:28h | UTC
Review: Non-alcoholic fatty liver disease
29 Apr, 2021 | 08:30h | UTCNon-alcoholic fatty liver disease – The Lancet (free for a limited period)
M-A: Administration of vasopressor medications through a peripheral intravenous catheter is associated with low risk of adverse events
29 Apr, 2021 | 08:19h | UTCRelated Meta-Analysis: Complication of vasopressor infusion through peripheral venous catheter (study and commentary on Twitter)
Review: Systemic and organ-specific immune-related manifestations of COVID-19 – over 70 different systemic and organ-specific immune-related disorders have been reported
28 Apr, 2021 | 08:42h | UTCSystemic and organ-specific immune-related manifestations of COVID-19 – Nature Reviews Rheumatology
Pre-post study: A hospital quality improvement intervention significantly reduced the rates of cesarean delivery for nulliparous, term, singleton, vertex births
29 Apr, 2021 | 08:21h | UTCHospital Quality Improvement Interventions, Statewide Policy Initiatives, and Rates of Cesarean Delivery for Nulliparous, Term, Singleton, Vertex Births in California – JAMA (free for a limited period)
Editorial: Initiatives to Reduce Cesarean Delivery Rates for Low-risk First Births – JAMA
Commentary on Twitter (thread – click for more)
"Rates of cesarean delivery for NTSV births in California decreased [from 26% to 22.8%] in the setting of a coordinated hospital-level collaborative and statewide initiatives designed to support vaginal birth.
"The rest of the US had no change."https://t.co/jwKkQZ4nix @cmqcc
— Ben Harder #BlackLivesMatter (@benharder) April 27, 2021
CDC says fully vaccinated Americans can go outside without masks – but masks still needed in crowds
28 Apr, 2021 | 08:44h | UTCCDC Guidance: Choosing Safer Activities – Centers for Disease Control and Prevention
Commentaries: CDC: If You’re Vaccinated, You Don’t Need To Mask Outdoors (Unless You’re In A Crowd) – NPR AND CDC: Fully vaccinated Americans can go maskless outdoors – CIDRAP
Commentary on Twitter (thread – click for more)
If you are fully vaccinated against #COVID19, you can start doing many things that you had stopped doing because of the pandemic. If you haven’t been vaccinated yet, get a vaccine as soon as you can. See full details: https://t.co/s5kXwg65fB pic.twitter.com/fvhehUiiCi
— CDC (@CDCgov) April 27, 2021
Podcast: Congenital Heart Disease for the General Pediatrician
29 Apr, 2021 | 08:18h | UTC#24: Congenital Heart Disease for the General Pediatrician – The Cribsiders
Socioeconomic status determines COVID-19 incidence and related mortality in Santiago, Chile
28 Apr, 2021 | 08:41h | UTC
Commentary on Twitter
An analysis of #COVID19 incidence and mortality in Santiago, Chile, highlights major consequences of healthcare disparities in a highly segregated city, showing that these inequalities disproportionately affected younger people @OxfordStats @HarvardChanSPH https://t.co/8f2Q2PdqBj pic.twitter.com/Ip1cikxvi7
— Science Magazine (@ScienceMagazine) April 27, 2021
Covid-19 in India: Cases, deaths and oxygen supply
28 Apr, 2021 | 08:40h | UTCCovid-19 in India: Cases, deaths and oxygen supply – BBC
See also: In Covid’s grip, India gasps for air: ‘If there is an apocalypse, this has to be one’ – STAT
How the UK found the first effective Covid-19 treatment — and saved a million lives (about the RECOVERY trial and the effects of Dexamethasone)
28 Apr, 2021 | 08:36h | UTCHow the UK found the first effective Covid-19 treatment — and saved a million lives – Vox
Related: Covid-19: The Inside Story of the RECOVERY Trial AND Covid: The London bus trip that saved maybe a million lives – BBC
Scientists say the rush to do Covid research led to a whole lot of waste
28 Apr, 2021 | 08:34h | UTCScientists Say The Rush To Do COVID Research Led To A Whole Lot Of Waste – NPR
Original Article: How COVID-19 has fundamentally changed clinical research in global health – The Lancet Global Health
Related: Data Show Panic and Disorganization Dominate the Study of Covid-19 Drugs (other commentaries on the subject)
See also: The Lancet Series: Clinical Trials in Global Health
Commentary on Twitter (thread – click for more)
Quantity > quality? The magnitude of #COVID19 research of questionable methodological quality reveals an urgent need to optimise clinical trial research—but how?
A new @LancetGH Series discusses challenges and solutions. Read https://t.co/z4SluR3yuh 1/5 pic.twitter.com/94RRVT0qhF
— The Lancet (@TheLancet) April 16, 2021
Tracking the Evolution of a ‘Variant of Concern’ in Brazil – “P.1 may be 1.7 to 2.4 times more transmissible than earlier variants”
28 Apr, 2021 | 08:38h | UTCTracking the Evolution of a ‘Variant of Concern’ in Brazil – NIH Director’s Blog
Related: Genomics and epidemiology of the P.1 SARS-CoV-2 lineage in Manaus, Brazil – Science
Overview of SARS-CoV-2 infection in adults living with HIV – Low CD4 cell counts, or untreated HIV infection is associated a more severe clinical course
28 Apr, 2021 | 08:32h | UTCOverview of SARS-CoV-2 infection in adults living with HIV – The Lancet HIV
Commentary on Twitter
New Review: Overview of SARS-CoV-2 infection in adults living with HIV: https://t.co/xXTntfIYPF pic.twitter.com/6w6MUSbo3n
— The Lancet HIV (@TheLancetHIV) April 27, 2021
Pediatric intensive care challenges caused by indirect effects of the COVID-19 pandemic
28 Apr, 2021 | 08:33h | UTC
Commentary on Twitter
Impact of #COVID19 #pandemic on #PedsICU: less visible vs adult ICU but all-pervasive, substantial & likely long-lasting
➡️on children
➡️on families
➡️on organizations
➡️on PICU team@Dr_Hari_Krishna @PollakUri Shekerdemian L #FOAMcc #COVIDFOAM on @yourICM https://t.co/OyI9etm1a2 pic.twitter.com/1bqi1oKlMk— Intensive Care Medicine (@yourICM) April 27, 2021
Systematic review: Interventions for increasing solid organ donor registration
28 Apr, 2021 | 08:11h | UTCInterventions for increasing solid organ donor registration – Cochrane Library
Summary: Interventions for increasing solid organ donor registration – Cochrane Library
American Academy of Orthopedic Surgeons Clinical Practice Guideline Summary for Limb Salvage or Early Amputation
28 Apr, 2021 | 08:14h | UTC
USPSTF Statement recommends screening for hypertension in adults 18 years or older with office blood pressure measurement – diagnostic confirmation with blood pressure measurements outside of the clinical setting is advised before starting treatment
28 Apr, 2021 | 08:16h | UTCEvidence Report: Screening for Hypertension in Adults: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force – JAMA
Author Interview: USPSTF Recommendation: Screening for Hypertension in Adults
Editorials: The USPSTF Recommendation on Blood Pressure Screening: Making 2021 the Transformative Year in Controlling Hypertension AND USPSTF Recommendation Statement on Hypertension Screening in Adults—Where Do We Go From Here? – JAMA Network Open AND Will the 2021 USPSTF Hypertension Screening Recommendation Decrease or Worsen Racial/Ethnic Disparities in Blood Pressure Control? – JAMA Network Open AND USPSTF Recommendations for Screening for Hypertension in Adults: It Is Time to Unmask Hypertensive Risk – JAMA Cardiology
JAMA Patient Page: Screening for Hypertension in Adults
Systematic Review: Disease‐modifying treatments for primary autoimmune hemolytic anemia
28 Apr, 2021 | 08:09h | UTCDisease‐modifying treatments for primary autoimmune haemolytic anaemia – Cochrane Library
Summary: Treatment for primary autoimmune haemolytic anaemia – Cochrane Library
M-A: Effectiveness of intrapartum fetal surveillance to improve maternal and neonatal outcomes – “none of the newer surveillance methods seem to significantly reduce emergency cesarean deliveries in labor or neonatal morbidity compared with using simple intermittent auscultation of the fetal heart”
28 Apr, 2021 | 08:08h | UTC
ASCO Guideline: Management of Salivary Gland Malignancy
28 Apr, 2021 | 08:13h | UTCManagement of Salivary Gland Malignancy: ASCO Guideline – Journal of Clinical Oncology
Consensus on pre-operative total knee replacement education and prehabilitation recommendations: a UK-based modified Delphi study
28 Apr, 2021 | 08:01h | UTC
RCT: Closure vs. non-closure of mesenteric defects during laparoscopic gastric bypass surgery – In this single-center trial, routine closure of the mesenteric defects in laparoscopic Roux-en-Y gastric bypass with clips was associated with a lower rate of internal herniation
28 Apr, 2021 | 08:04h | UTCRandomized clinical trial on closure versus non-closure of mesenteric defects during laparoscopic gastric bypass surgery – British Journal of Surgery (link to abstract – $ for full-text)
Commentary on Twitter
Free in February's BJS: Randomized clinical trial on closure versus non-closure of mesenteric defects during laparoscopic gastric bypass surgery https://t.co/rFl0WdZI6v @AmyLightnerMD @bplwijn @des_winter @ksoreide @MalinASund @evanscolorectal @nfmkok @robhinchliffe1 @young_bjs pic.twitter.com/YnwUwDCWhB
— BJS (@BJSurgery) April 10, 2021
Safety of tranexamic acid in hip and knee arthroplasty in high-risk patients – this large observational study did not show an increased risk for venous thromboembolism, myocardial infarction, seizures, ischemic strokes, or transient ischemic attacks, irrespective of patient high-risk status at baseline
28 Apr, 2021 | 07:59h | UTCSafety of Tranexamic Acid in Hip and Knee Arthroplasty in High-risk Patients – Anesthesiology (link to abstract – $ for full-text)
Commentaries on Twitter
Our study online @_Anesthesiology today: safety of TXA in high-risk pts ➡️data from 500 hospitals shows no increased risks of VTE, MI, seizures, ischemic stroke or TIA. @HipKneeDoc @MountSinaiOrtho 🔗 https://t.co/za7SH8C7rj pic.twitter.com/J8hoW6stNm
— Jashvant Poeran (@jashvant_p) April 16, 2021
Safety of Tranexamic Acid in Hip and Knee Arthroplasty in High-risk Patients @_Anesthesiology
👉TXA in high risk pts is not associated w/ venous thromboembolism, myocardial infarction, seizures, ischemic strokes, or TIAshttps://t.co/DwZe0brJ9L pic.twitter.com/KGcRCftcOl
— Emily Sharpe, MD, FASA (@emilysharpe) April 22, 2021